Anti-HSP auto-antibodies enhance HSP-induced pro-inflammatory cytokine production in human monocytic cells via Toll-like receptors

International Immunology

Volumn 18, Issue 4, 2006, Pages 573-580

  Yokota, Shin ichi ^a   Minota, Seiji ^b   Fujii, Nobuhiro ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Auto antibody; Heat shock protein; Proinflammatory cytokine; Rheumatic autoimmune disease; Toll like receptor

Indexed keywords

AUTOANTIBODY; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 60; HEAT SHOCK PROTEIN 70; IMMUNOGLOBULIN F(AB')2 FRAGMENT; IMMUNOGLOBULIN F(AB) FRAGMENT; INTERLEUKIN 8; MONOCLONAL ANTIBODY; PROTEIN ANTIBODY; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ANTIBODY TITER; ARTICLE; AUTOIMMUNE DISEASE; BLOOD SAMPLING; CONTROLLED STUDY; CROSS LINKING; CYTOKINE PRODUCTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MONOCYTE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RHEUMATIC DISEASE;

ANIMALS; AUTOANTIBODIES; AUTOIMMUNE DISEASES; CELL LINE; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEAT-SHOCK PROTEINS; HUMANS; INTERLEUKIN-8; MICE; MONOCYTES; TOLL-LIKE RECEPTORS; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33645223685     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxh399     Document Type: Article

References (35)

1. Hartl, F. U. 1996. Molecular chaperones in cellular protein folding. Nature 381:571.
2. Srivastava, P. 2002. Roles of heat-shock proteins in innate and adaptive immunity. Nat. Rev. Immunol. 2:185.
3. Binder, R. J., Vatner, R. and Srivastava, P. 2004. The heat-shock protein receptors: Some answers and more questions. Tissue Antigens 64:442.
4. Ohashi, K., Burkart, V., Flohe, S. and Kolb, H. 2000. Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J. Immunol. 164:558.
5. Asea, A. 2003. Chaperokine-induced signal transduction pathways. Exerc. Immunol. Rev. 9:25.
6. Vabulas, R. M., Wagner, H. and Schild, H. 2002. Heat shock proteins as ligands of toll-like receptors. Curr. Top. Microbiol. Immunol. 270:169.
7. Takeda, K. and Akira, S. 2005. Toll-like receptors in innate immunity. Int. Immunol. 17:1.
8. Delneste, Y. 2004. Scavenger receptors and heat-shock protein-mediated antigen cross-presentation. Biochem. Soc. Trans. 32:633.
9. Gardai, S. J., Xiao, Y. Q., Dickinson, M. et al. 2003. By binding SIRPα or calreticulin/CD91, lung collectins act as dual function surveillance molecules to suppress or enhance inflammation. Cell 115:13.
10. Delneste, Y., Magistrelli, G., Gauchat, J. et al. 2002. Involvement of LOX-1 in dendritic cell-mediated antigen cross-presentation. Immunity 17:353.
11. Becker, T., Hartl, F. U. and Wieland, F. 2002. CD40, an extracellular receptor for binding and uptake of Hsp70-peptide complexes. J. Cell Biol. 158: 1277.
12. Winfield, J. B. and Jarjour, W. N. 1991. Stress proteins, autoimmunity, and autoimmune disease. Curr. Top. Microbiol. Immunol. 167:161.
13. Tishler, M. and Shoenfeld,Y. 1996. Anti-heat-shock protein antibodies in rheumatic and autoimmune diseases. Semin. Arthritis Rheum. 26:558.
14. Xu, Q. 2002. Role of heat shock proteins in atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 22:1547.
15. Yonekura, K., Yokota, S., Tanaka, S. et al. 2004. Prevalence of anti-heat shock protein antibodies in cerebrospinal fluids of patients with Guillain-Barre syndrome. J. Neuroimmunol. 156:204.
16. Chiba, S., Yokota, S., Yonekura, K. et al. 2006. Autoantibodies against HSP70 family proteins were detected in the cerebrospinal fluid from patients with multiple sclerosis. J. Neurol. Sci. 241:39.
17. Wahl, L. M. and Smith, P. D. 1995. Isolation of macrophage populations. In Coligan, J. E., Kruisbeek, A. M., Margulies, D. H., Shevach, E. M. and Strober, W., eds, Current Protocols in Immunology, Vol. 2, unit 7.6.1. John Wiley & Sons, Inc., Philadelphia.
18. Yokota, S., Hirata, D., Minota, S. et al. 2000. Autoantibodies against chaperonin CCT in human sera with rheumatic autoimmune diseases: comparison with antibodies against other Hsp60 family proteins. Cell Stress Chaperones 5:337.
19. Arnett, F. C., Edworthy, S. M., Bloch, D. A. et al. 1988. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 31:315.
20. Tan, E. M., Cohen, A. S., Fries, J. F., et al. 1982. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 25:1271.
21. Vitali, C., Bombardieri, S., Moutsopoulos, H. M. et al. 1993. Preliminary criteria for the classification of Sjögren's syndrome. Results of a prospective concerted action supported by the European Community. Arthritis Rheum. 36:340.
22. Smith, M. F., Jr, Mitchell, A., Li, G. et al. 2003. Toll-like receptor (TLR) 2 and TLR5, but not TLR4, are required for Helicobacter pylori-induced NF-κB activation and chemokine expression by epithelial cells. J. Biol. Chem. 278:32552.
23. Gao, B. and Tsan, M. F. 2004. Induction of cytokines by heat shock proteins and endotoxin in murine macrophages. Biochem. Biophys. Res. Commun. 317:1149.
24. Tsan, M. F. and Gao, B. 2004. Cytokine function of heat shock proteins. Am. J. Physiol. Cell Physiol. 286:C739.
25. Hirata, D., Hirai, I., Iwamoto, M. et al. 1997. Preferential binding with Escherichia coli hsp60 of antibodies prevalent in sera from patients with rheumatoid arthritis. Clin. Immunol. Immunopathol. 82:141.
26. Klimiuk, P. A., Sierakowski, S., Latosiewicz, R. et al. 2005. Histological patterns of synovitis and serum chemokines in patients with rheumatoid arthritis. J. Rheumatol. 32:1666.
27. Holcombe, R. F., Baethge, B. A., Wolf, R. E. et al. 1994. Correlation of serum interleukin-8 and cell surface lysosome-associated membrane protein expression with clinical disease activity in systemic lupus erythematosus. Lupus 3:97.
28. Schett, G., Xu, Q., Amberger, A. et al. 1995. Autoantibodies against heat shock protein 60 mediate endothelial cytotoxicity. J. Clin. Invest. 96:2569.
29. Lewthwaite, J., Owen, N., Coates, A., Henderson, B. and Steptoe, A. 2002. Circulating human heat shock protein 60 in the plasma of British civil servants: Relationship to physiological and psychosocial stress. Circulation 106:196.
30. Pockley, A. G., Wu, R., Lemne, C., Kiessling, R., de Faire, U. and Frostegard, J. 2000. Circulating heat shock protein 60 is associated with early cardiovascular disease. Hypertension 36:303.
31. Genth-Zotz, S., Bolger, A. P., Kalra, P. R. et al. 2004. Heat shock protein 70 in patients with chronic heart failure: Relation to disease severity and survival. Int. J. Cardiol. 96:397.
32. Pockley, A. G., Georgiades, A., Thulin, T., de Faire, U. and Frostegard, J. 2003. Serum heat shock protein 70 levels predict the development of atherosclerosis in subjects with established hypertension. Hypertension 42:235.
33. Wright, B. H., Corton, J. M., El-Nahas, A. M., Wood, R. F. and Pockley, A. G. 2000. Elevated levels of circulating heat shock protein 70 (Hsp70) in peripheral and renal vascular disease. Heart Vessels 15:18.
34. Dybdahl, B., Slordahl, S. A., Waage, A., Kierulf, P., Espevik, T. and Sundan, A. 2005. Myocardial ischaemia and the inflammatory response: release of heat shock protein 70 after myocardial infarction. Heart 91:299.
35. Seitz, M., Dewald, B., Ceska, M., Gerber, N. and Baggiolini, M. 1992. Interleukin-8 in inflammatory rheumatic diseases: Synovial fluid levels, relation to rheumatoid factors, production by mononuclear cells, and effects of gold sodium thiomalate and methotrexate. Rheumatol. Int. 12:159.