Partial A 1 adenosine receptor agonist regulates cardiac substrate utilization in insulin-resistant rats in vivo

Journal of Pharmacology and Experimental Therapeutics

Volumn 328, Issue 1, 2009, Pages 306-311

  Shearer, Jane ^a,c   Severson, David L ^a   Su, Lin ^a   Belardinelli, Luiz ^b   Dhalla, Arvinder K ^b  

^a UNIVERSITY OF CALGARY   (Canada)

^b CV THERAPEUTICS INC   (United States)

^c UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 [6 [(2 HYDROXYCYCLOPENTYL)AMINO]PURIN 9 YL] 5 [(2 FLUOROPHENYLTHIO)METHYL]OXOLANE 3,4 DIOL; 2 BROMOPALMITIC ACID; ADENOSINE A1 RECEPTOR AGONIST; DEOXYGLUCOSE; FATTY ACID; GLUCOSE; INSULIN; PARTIAL AGONIST; UNCLASSIFIED DRUG; 2 (6 ((2 HYDROXYCYCLOPENTYL)AMINO)PURIN 9 YL) 5 ((2 FLUOROPHENYLTHIO)METHYL)OXOLANE 3,4 DIOL; 2-(6-((2-HYDROXYCYCLOPENTYL)AMINO)PURIN-9-YL)-5-((2-FLUOROPHENYLTHIO)METHYL)OXOLANE-3,4-DIOL; ADENOSINE; ADENOSINE A1 RECEPTOR; DRUG DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLEARANCE; CONTROLLED STUDY; GLUCOSE BLOOD LEVEL; GLUCOSE UTILIZATION; HEART MUSCLE METABOLISM; IN VIVO STUDY; INSULIN RESISTANCE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TREATMENT RESPONSE; ANIMAL; BLOOD; CAROTID ARTERY; DRUG EFFECT; DRUG POTENTIATION; FAT INTAKE; GENE EXPRESSION REGULATION; HEART; HEART MUSCLE; JUGULAR VEIN; LIPOLYSIS; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ADENOSINE; ANIMALS; CAROTID ARTERIES; DIETARY FATS; FATTY ACIDS, NONESTERIFIED; GENE EXPRESSION REGULATION; GLUCOSE; HEART; INSULIN; INSULIN RESISTANCE; JUGULAR VEINS; LIPOLYSIS; MALE; MODELS, ANIMAL; MYOCARDIUM; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ADENOSINE A1;

EID: 59149094795     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.143594     Document Type: Article

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