메뉴 건너뛰기




Volumn 2009, Issue , 2009, Pages

Characterization of a novel polymorphism in PPARG regulatory region associated with type 2 diabetes and diabetic retinopathy in italy

Author keywords

[No Author keywords available]

Indexed keywords

PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN;

EID: 58949092541     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2009/126917     Document Type: Article
Times cited : (36)

References (30)
  • 2
    • 0030951143 scopus 로고    scopus 로고
    • Identification, characterization, and tissue distribution of human peroxisome proliferator-activated receptor (PPAR) isoforms PPARγ2 versus PPARγ1 and activation with retinoid X receptor agonists and antagonists
    • Mukherjee R., Jow L., Croston G. E., Paterniti J. R. Jr., Identification, characterization, and tissue distribution of human peroxisome proliferator-activated receptor (PPAR) isoforms PPARγ2 versus PPARγ1 and activation with retinoid X receptor agonists and antagonists The Journal of Biological Chemistry 1997 272 12 8071 8076
    • (1997) The Journal of Biological Chemistry , vol.272 , Issue.12 , pp. 8071-8076
    • Mukherjee, R.1    Jow, L.2    Croston, G.E.3    Paterniti Jr., J.R.4
  • 3
    • 22544441159 scopus 로고    scopus 로고
    • A novel peroxisome proliferator-activated receptorγisoform with dominant negative activity generated by alternative splicing
    • Sabatino L., Casamassimi A., Peluso G., A novel peroxisome proliferator-activated receptorγisoform with dominant negative activity generated by alternative splicing The Journal of Biological Chemistry 2005 280 28 26517 26525
    • (2005) The Journal of Biological Chemistry , vol.280 , Issue.28 , pp. 26517-26525
    • Sabatino, L.1    Casamassimi, A.2    Peluso, G.3
  • 4
    • 0035851187 scopus 로고    scopus 로고
    • PPARγ: aa nuclear regulator of metabolism, differentiation, and cell growth
    • Rosen E. D., Spiegelman B. M., PPARγ: a nuclear regulator of metabolism, differentiation, and cell growth The Journal of Biological Chemistry 2001 276 41 37731 37734
    • (2001) The Journal of Biological Chemistry , vol.276 , Issue.41 , pp. 37731-37734
    • Rosen, E.D.1    Spiegelman, B.M.2
  • 5
    • 0035093082 scopus 로고    scopus 로고
    • Effect of the peroxisome proliferator-activated receptor-γ2 Pro12 Ala variant on obesity, glucose homeostasis, and blood pressure in members of familial type 2 diabetic kindreds
    • Hasstedt S. J., Ren Q.-F., Teng K., Elbein S. C., Effect of the peroxisome proliferator-activated receptor-γ2 Pro12 Ala variant on obesity, glucose homeostasis, and blood pressure in members of familial type 2 diabetic kindreds The Journal of Clinical Endocrinology and Metabolism 2001 86 2 536 541
    • (2001) The Journal of Clinical Endocrinology and Metabolism , vol.86 , Issue.2 , pp. 536-541
    • Hasstedt, S.J.1    Ren, Q.-F.2    Teng, K.3    Elbein, S.C.4
  • 6
    • 0345164399 scopus 로고    scopus 로고
    • Molecular scanning of the human peroxisome proliferator activated receptorγ(hPPARγ) gene in diabetic Caucasians: Identification of a Pro12Ala PPARγ2 missense mutation
    • Yen C.-J., Beamer B. A., Negri C., Molecular scanning of the human peroxisome proliferator activated receptorγ(hPPARγ) gene in diabetic Caucasians: identification of a Pro12Ala PPARγ2 missense mutation Biochemical and Biophysical Research Communications 1997 241 2 270 274
    • (1997) Biochemical and Biophysical Research Communications , vol.241 , Issue.2 , pp. 270-274
    • Yen, C.-J.1    Beamer, B.A.2    Negri, C.3
  • 8
    • 0034607051 scopus 로고    scopus 로고
    • Inhibitory effect of a proline-to-alanine substitution at codon 12 of peroxisome proliferator-activated receptor-γ2 on thiazolidinedione-induced adipogenesis
    • Masugi J., Tamori Y., Mori H., Koike T., Kasuga M., Inhibitory effect of a proline-to-alanine substitution at codon 12 of peroxisome proliferator- activated receptor-γ2 on thiazolidinedione-induced adipogenesis Biochemical and Biophysical Research Communications 2000 268 1 178 182
    • (2000) Biochemical and Biophysical Research Communications , vol.268 , Issue.1 , pp. 178-182
    • Masugi, J.1    Tamori, Y.2    Mori, H.3    Koike, T.4    Kasuga, M.5
  • 9
    • 10644251916 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γcalls for activation in moderation: Lessons from genetics and pharmacology
    • Knouff C., Auwerx J., Peroxisome proliferator-activated receptor-γcalls for activation in moderation: lessons from genetics and pharmacology Endocrine Reviews 2004 25 6 899 918
    • (2004) Endocrine Reviews , vol.25 , Issue.6 , pp. 899-918
    • Knouff, C.1    Auwerx, J.2
  • 10
    • 12944308811 scopus 로고    scopus 로고
    • Common polymorphisms of the PPAR-γ2 (Pro12Ala) and PGC -1α (Gly482Ser) genes are associated with the conversion from impaired glucose tolerance to type 2 diabetes in the STOP-NIDDM trial
    • Andrulionytè L., Zacharova J., Chiasson J.-L., Laakso M., Common polymorphisms of the PPAR-γ2 (Pro12Ala) and PGC -1α (Gly482Ser) genes are associated with the conversion from impaired glucose tolerance to type 2 diabetes in the STOP-NIDDM trial Diabetologia 2004 47 12 2176 2184
    • (2004) Diabetologia , vol.47 , Issue.12 , pp. 2176-2184
    • Andrulionytè, L.1    Zacharova, J.2    Chiasson, J.-L.3    Laakso, M.4
  • 11
    • 0036222003 scopus 로고    scopus 로고
    • Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-γ2 (PPARγ2) is associated with higher levels of total cholesterol and LDL-cholesterol in male caucasian type 2 diabetes patients
    • Zietz B., Barth N., Spiegel D., Schmitz G., Schölmerich J., Schöffler A., Pro12Ala polymorphism in the peroxisome proliferator- activated receptor-γ2 (PPARγ2) is associated with higher levels of total cholesterol and LDL-cholesterol in male caucasian type 2 diabetes patients Experimental and Clinical Endocrinology and Diabetes 2002 110 2 60 66
    • (2002) Experimental and Clinical Endocrinology and Diabetes , vol.110 , Issue.2 , pp. 60-66
    • Zietz, B.1    Barth, N.2    Spiegel, D.3    Schmitz, G.4    Schölmerich, J.5    Schöffler, A.6
  • 12
    • 0345275787 scopus 로고    scopus 로고
    • The human peroxisome proliferator-activated receptorγ2 (PPARγ2) Pro12Ala polymorphism is associated with decreased risk of diabetic nephropathy in patients with type 2 diabetes
    • Caramori M. L., Canani L. H., Costa L. A., Gross J. L., The human peroxisome proliferator-activated receptorγ2 (PPARγ2) Pro12Ala polymorphism is associated with decreased risk of diabetic nephropathy in patients with type 2 diabetes Diabetes 2003 52 12 3010 3013
    • (2003) Diabetes , vol.52 , Issue.12 , pp. 3010-3013
    • Caramori, M.L.1    Canani, L.H.2    Costa, L.A.3    Gross, J.L.4
  • 13
    • 24944550759 scopus 로고    scopus 로고
    • Gly482Ser polymorphism of the peroxisome proliferator-activated receptor-γcoactivator-1 gene might be a risk factor for diabetic retinopathy in Slovene population (Caucasians) with type 2 diabetes and the Pro12Ala polymorphism of the PPARγgene is not
    • Petrovič M. G., Kunej T., Peterlin B., Dovč P., Petrovič D., Gly482Ser polymorphism of the peroxisome proliferator-activated receptor-γcoactivator-1 gene might be a risk factor for diabetic retinopathy in Slovene population (Caucasians) with type 2 diabetes and the Pro12Ala polymorphism of the PPARγgene is not Diabetes/Metabolism Research and Reviews 2005 21 5 470 474
    • (2005) Diabetes/Metabolism Research and Reviews , vol.21 , Issue.5 , pp. 470-474
    • Petrovič, M.G.1    Kunej, T.2    Peterlin, B.3    Dovč, P.4    Petrovič, D.5
  • 14
    • 2342597134 scopus 로고    scopus 로고
    • Bifunctional properties of peroxisome proliferator-activated receptorγ1 in KDR gene regulation mediated via interaction with both Sp1 and Sp3
    • Sassa Y., Hata Y., Aiello L. P., Taniguchi Y., Kohno K., Ishibashi T., Bifunctional properties of peroxisome proliferator-activated receptorγ1 in KDR gene regulation mediated via interaction with both Sp1 and Sp3 Diabetes 2004 53 5 1222 1229
    • (2004) Diabetes , vol.53 , Issue.5 , pp. 1222-1229
    • Sassa, Y.1    Hata, Y.2    Aiello, L.P.3    Taniguchi, Y.4    Kohno, K.5    Ishibashi, T.6
  • 16
    • 0037677523 scopus 로고    scopus 로고
    • A functional variant in the peroxisome proliferator-activated receptorγ2 promoter is associated with predictors of obesity and type 2 diabetes in Pima Indians
    • Muller Y. L., Bogardus C., Beamer B. A., Shuldiner A. R., Baier L. J., A functional variant in the peroxisome proliferator-activated receptorγ2 promoter is associated with predictors of obesity and type 2 diabetes in Pima Indians Diabetes 2003 52 7 1864 1871
    • (2003) Diabetes , vol.52 , Issue.7 , pp. 1864-1871
    • Muller, Y.L.1    Bogardus, C.2    Beamer, B.A.3    Shuldiner, A.R.4    Baier, L.J.5
  • 17
    • 34548686797 scopus 로고    scopus 로고
    • Identification and expression analysis of novel Jakmip1 transcripts
    • Costa V., Conte I., Ziviello C., Identification and expression analysis of novel Jakmip1 transcripts Gene 2007 402 1-2 1 8
    • (2007) Gene , vol.402 , Issue.12 , pp. 1-8
    • Costa, V.1    Conte, I.2    Ziviello, C.3
  • 19
    • 0031466983 scopus 로고    scopus 로고
    • From genotypes to genes: Doubling the sample size
    • Sasieni P. D., From genotypes to genes: doubling the sample size Biometrics 1997 53 4 1253 1261
    • (1997) Biometrics , vol.53 , Issue.4 , pp. 1253-1261
    • Sasieni, P.D.1
  • 20
    • 1842866370 scopus 로고    scopus 로고
    • Association of the Pro12Ala and C1431T variants of PPARG and their haplotypes with susceptibility to type 2 diabetes
    • Doney A. S. F., Fischer B., Cecil J. E., Association of the Pro12Ala and C1431T variants of PPARG and their haplotypes with susceptibility to type 2 diabetes Diabetologia 2004 47 3 555 558
    • (2004) Diabetologia , vol.47 , Issue.3 , pp. 555-558
    • Doney, A.S.F.1    Fischer, B.2    Cecil, J.E.3
  • 21
    • 0036320727 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ2 polymorphism Pro12Ala is associated with nephropathy in type 2 diabetes: The Berlin Diabetes Mellitus (BeDiaM) Study
    • Herrmann S.-M., Ringel J., Wang J.-G., Staessen J. A., Brand E., Peroxisome proliferator-activated receptor-γ2 polymorphism Pro12Ala is associated with nephropathy in type 2 diabetes: The Berlin Diabetes Mellitus (BeDiaM) Study Diabetes 2002 51 8 2653 2657
    • (2002) Diabetes , vol.51 , Issue.8 , pp. 2653-2657
    • Herrmann, S.-M.1    Ringel, J.2    Wang, J.-G.3    Staessen, J.A.4    Brand, E.5
  • 22
    • 0033624575 scopus 로고    scopus 로고
    • The common PPARγPro12Ala polymorphism is associated with decreased risk of type 2 diabetes
    • Altshuler D., Hirschhorn J. N., Klannemark M., The common PPARγPro12Ala polymorphism is associated with decreased risk of type 2 diabetes Nature Genetics 2000 26 1 76 80
    • (2000) Nature Genetics , vol.26 , Issue.1 , pp. 76-80
    • Altshuler, D.1    Hirschhorn, J.N.2    Klannemark, M.3
  • 23
    • 0033304551 scopus 로고    scopus 로고
    • Two polymorphisms in the peroxisome proliferator-activated receptor-γgene are associated with severe overweight among obese women
    • Valve R., Sivenius K., Miettinen R., Two polymorphisms in the peroxisome proliferator-activated receptor-γgene are associated with severe overweight among obese women The Journal of Clinical Endocrinology and Metabolism 1999 84 10 3708 3712
    • (1999) The Journal of Clinical Endocrinology and Metabolism , vol.84 , Issue.10 , pp. 3708-3712
    • Valve, R.1    Sivenius, K.2    Miettinen, R.3
  • 25
    • 0035798713 scopus 로고    scopus 로고
    • The mechanisms by which both heterozygous peroxisome proliferator- activated receptorγ(PPARγ) deficiency and PPARγagonist improve insulin resistance
    • Yamauchi T., Kamon J., Waki H., The mechanisms by which both heterozygous peroxisome proliferator-activated receptorγ(PPARγ) deficiency and PPARγagonist improve insulin resistance The Journal of Biological Chemistry 2001 276 44 41245 41254
    • (2001) The Journal of Biological Chemistry , vol.276 , Issue.44 , pp. 41245-41254
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3
  • 26
    • 24344455975 scopus 로고    scopus 로고
    • Estrogen receptorα binds to peroxisome proliferator-activated receptor response element and negatively interferes with peroxisome proliferator-activated receptorγsignaling in breast cancer cells
    • Bonofiglio D., Gabriele S., Aquila S., Estrogen receptorα binds to peroxisome proliferator-activated receptor response element and negatively interferes with peroxisome proliferator-activated receptorγsignaling in breast cancer cells Clinical Cancer Research 2005 11 17 6139 6147
    • (2005) Clinical Cancer Research , vol.11 , Issue.17 , pp. 6139-6147
    • Bonofiglio, D.1    Gabriele, S.2    Aquila, S.3
  • 27
    • 45349084588 scopus 로고    scopus 로고
    • PPARγagonists: Potential as therapeutics for neovascular retinopathies
    • Pershadsingh H. A., Moore D. M., PPARγagonists: potential as therapeutics for neovascular retinopathies PPAR Research 2008 2008 13
    • (2008) PPAR Research , vol.2008 , pp. 13
    • Pershadsingh, H.A.1    Moore, D.M.2
  • 28
    • 33750598226 scopus 로고    scopus 로고
    • Effects of peroxisome proliferator-activated receptorγand its ligand on blood-retinal barrier in a streptozotocin-induced diabetic model
    • Muranaka K., Yanagi Y., Tamaki Y., Effects of peroxisome proliferator-activated receptorγand its ligand on blood-retinal barrier in a streptozotocin-induced diabetic model Investigative Ophthalmology and Visual Science 2006 47 10 4547 4552
    • (2006) Investigative Ophthalmology and Visual Science , vol.47 , Issue.10 , pp. 4547-4552
    • Muranaka, K.1    Yanagi, Y.2    Tamaki, Y.3
  • 29
    • 20544434995 scopus 로고    scopus 로고
    • Troglitazone reverses the inhibition of nitric oxide production by high glucose in cultured bovine retinal pericytes
    • Kim J., Oh Y.-S., Shinn S.-H., Troglitazone reverses the inhibition of nitric oxide production by high glucose in cultured bovine retinal pericytes Experimental Eye Research 2005 81 1 65 70
    • (2005) Experimental Eye Research , vol.81 , Issue.1 , pp. 65-70
    • Kim, J.1    Oh, Y.-S.2    Shinn, S.-H.3
  • 30
    • 8644275374 scopus 로고    scopus 로고
    • The 161TT genotype in the exon 6 of the peroxisome-proliferator-activated receptorγgene is associated with premature acute myocardial infarction and increased lipid peroxidation in habitual heavy smokers
    • Chao T.-H., Li Y.-H., Chen J.-H., The 161TT genotype in the exon 6 of the peroxisome-proliferator-activated receptorγgene is associated with premature acute myocardial infarction and increased lipid peroxidation in habitual heavy smokers Clinical Science 2004 107 5 461 466
    • (2004) Clinical Science , vol.107 , Issue.5 , pp. 461-466
    • Chao, T.-H.1    Li, Y.-H.2    Chen, J.-H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.