Design and evaluation of pH-independent pulsatile release pellets containing isosorbide-5-mononitrate

Chemical and Pharmaceutical Bulletin

Volumn 57, Issue 1, 2009, Pages 55-60

  Liu, Yao ^a   Liu, Songqing ^a   Dai, Qing ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Box behnken experimental design; Isosorbide 5 mononitrate; Pulsatile release pellet

Indexed keywords

ISOSORBIDE 5 NITRATE; LACTOSE; MICROCRYSTALLINE CELLULOSE; UNCLASSIFIED DRUG; WYNDALE; XINKANG;

ANGINA PECTORIS; ANIMAL EXPERIMENT; ARTICLE; DOG; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; NONHUMAN; PELLET EXTRUSION; PULSATILE DRUG RELEASE; PULSATILE RELEASE PELLET; SINGLE DRUG DOSE; SPHERONIZATION; TABLET FORMULATION;

ADMINISTRATION, ORAL; ANIMALS; DELAYED-ACTION PREPARATIONS; DOGS; DRUG DESIGN; DRUG STABILITY; HYDROGEN-ION CONCENTRATION; ISOSORBIDE DINITRATE; NITRIC OXIDE DONORS; REFERENCE STANDARDS;

EID: 58849155195     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.57.55     Document Type: Article

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