The role of intra- and extragenic compensatory mutations in the suppression of fluoroquinolone resistance in a Salmonella Typhimurium gyrA mutant (D87G)

Journal of Antimicrobial Chemotherapy

Volumn 63, Issue 2, 2009, Pages 290-294

  Preisler, Antje ^a   Heisig, Peter ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

Author keywords

Fitness; Gyrase; Multidrug transporters; Vaccines

Indexed keywords

ANTIBIOTIC AGENT; BACTERIAL PROTEIN; DNA TOPOISOMERASE (ATP HYDROLYSING) A; LIVE VACCINE; MACROLIDE; NALIDIXIC ACID; PHENYLALANYL ARGINYL BETA NAPHTHYLAMIDE; PROTEIN ACRA; PROTEIN ACRB; QUINOLONE DERIVATIVE; RIFAMPICIN; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; CONTROLLED STUDY; DNA SEQUENCE; DNA SUPERCOILING; DRUG DETERMINATION; GENE DELETION; GENE FUNCTION; GENE MUTATION; GENETIC COMPLEMENTATION; HOMOLOGOUS RECOMBINATION; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; MUTAGENESIS; MUTANT; NONHUMAN; PHENOTYPE; SALMONELLA TYPHIMURIUM; SEQUENCE ANALYSIS; WILD TYPE;

AMINO ACID SUBSTITUTION; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; DNA GYRASE; DNA MUTATIONAL ANALYSIS; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; FLUOROQUINOLONES; GENETIC COMPLEMENTATION TEST; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; PROTEIN STRUCTURE, QUATERNARY; SALMONELLA TYPHIMURIUM; SEQUENCE ANALYSIS, DNA; SEQUENCE DELETION; SUPPRESSION, GENETIC;

EID: 58849118049     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkn480     Document Type: Article

References (13)

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