Impact of the addition of sufentanil 5 μg or clonidine 75 μg on the minimum local analgesic concentration of ropivacaine for epidural analgesia in labour: A randomized comparison

International Journal of Obstetric Anesthesia

Volumn 17, Issue 4, 2008, Pages 315-321

  Dewandre, P Y ^a   Kirsch, M ^a   Bonhomme, V ^a   Columb, M ^b   Hans, P ^a   Brichant, J F ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Analgesia; Clonidine; Epidural; Labour; MLAC; Ropivacaine; Sufentanil

Indexed keywords

AMIDE; CLONIDINE; LOCAL ANESTHETIC AGENT; NARCOTIC ANALGESIC AGENT; ROPIVACAINE; SUFENTANIL;

ADULT; ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; EPIDURAL ANESTHESIA; FEMALE; HUMAN; OBSTETRIC ANALGESIA; PREGNANCY; RANDOMIZED CONTROLLED TRIAL;

ADULT; AMIDES; ANALGESIA, EPIDURAL; ANALGESIA, OBSTETRICAL; ANALGESICS, OPIOID; ANESTHETICS, LOCAL; CLONIDINE; DOUBLE-BLIND METHOD; FEMALE; HUMANS; PREGNANCY; SUFENTANIL;

EID: 58849117718     PISSN: 0959289X     EISSN: 15323374     Source Type: Journal    
DOI: 10.1016/j.ijoa.2008.05.005     Document Type: Article

References (43)

1. Olofsson C, Ekblom A, Ekman-Ordeberg G, Irestedt L. Obstetric outcome following epidural analgesia with bupivacaine-adrenaline 0.25% or bupivacaine 0.125% with sufentanil: a prospective randomized controlled study in 1000 parturients. Acta Anaesthesiol Scand 1998; 42: 284-92. (Pubitemid 28131376)
2. Murphy J D, Henderson K, Bowden M I, Lewis M, Cooper G M. Bupivacaine versus bupivacaine plus fentanyl for epidural analgesia: effect on maternal satisfaction. BMJ 1991; 302: 564-7.
3. Chestnut D H, Owen C L, Bates J N, Ostman L G, Choi W W, Geiger M W. Continuous infusion epidural analgesia during labor: a randomized, double-blinded comparison of 0.0625% bupivacaine/0.0002% fentanyl versus 0.125% bupivacaine. Anesthesiology 1988; 68: 754-9.
4. Vertommen J D, Vandermeulen E, Van Aken H et al. The effects of the addition of sufentanil to 0.125% bupivacaine on the quality of analgesia during labor and on the incidence of instrumental deliveries. Anesthesiology 1991; 74: 809-14.
5. Comparative obstetric mobile epidural trial (COMET) Study Group UK. Randomized controlled trial comparing traditional with two "mobile" epidural techniques. Anesthetic and Analgesic Efficacy. Anesthesiology 2002; 97: 1567-75.
6. Comparative obstetric mobile epidural trial (COMET) Study Group UK. Effect of low-dose mobile versus traditional epidural techniques on mode of delivery: a randomised controlled trial. Lancet 2001, 358: 19-23.
7. Landau R, Schiffer E, Morales M, Savoldelli G, Kern C. The dosesparing effect of clonidine added to ropivacaine for labor epidural analgesia. Anesth Analg 2002; 95: 728-34. (Pubitemid 35006866)
8. Gogarten W, Van De Velde M, Soetens F et al. A multicenter trial comparing different concentrations of ropivacaine plus sufentanil with bupivacaine plus sufentanil for patient-controlled epidural analgesia in labour. Eur J Anaesthesiol 2004; 21: 38-45. (Pubitemid 38029421)
9. Burnstein R, Buckland R, Pickett J A. A survey of epidural analgesia for labour in the United Kingdom. Anaesthesia 1999; 54: 634-40. (Pubitemid 29353856)
10. O'Meara M E, Gin T. Comparison of 0.125% bupivacaine with 0.125% bupivacaine and clonidine as extradural analgesia in the first stage of labour. Br J Anaesth 1993; 71: 651-6. (Pubitemid 23330991)
11. Cigarini I, Kaba A, Bonnet F et al. Epidural clonidine combined with bupivacaine for analgesia in labor. Effects on mother and neonate. Reg Anesth 1995; 20: 113-20.
12. Chassard D, Mathon L, Dailler F, Golfier F, Tournade J P, Bouletreau P. Extradural clonidine combined with sufentanil and 0.0625% bupivacaine for analgesia in labour. Br J Anaesth 1996; 77: 458-62. (Pubitemid 26341031)
13. Eisenach J C, De Kock M, Kimscha W. Alpha sub 2-adrenergic agonists for regional anaesthesia: a clinical review of clonidine (1984-1995). Anesthesiology 1996; 85: 655-74. (Pubitemid 26332620)
14. Tremlett M R, Kelly P J, Parkins J, Hughes D, Redfern N. Lowdose clonidine infusion during labour. Br J Anaesth 1999; 83: 257-61.
15. Aveline C, El Metaoua S, Masmoudi A, Boelle P Y, Bonet F. The effect of clonidine on the minimum local analgesic concentration of epidural ropivacaine during labor. Anesth Analg 2002; 95: 735-40. (Pubitemid 35006867)
16. D'Angelo R. Should we administer epidural or spinal clonidine during labor? Reg Anesth Pain Med 2000; 25: 3-4.
17. Lyons G, Columb M, Hawthorne L, Dresner M. Extradural pain relief in labour: bupivacaine sparing by extradural fentanyl is dose dependent. Br J Anaesth 1997; 78: 493-7. (Pubitemid 27226358)
18. Polley L S, Columb M O, Wagner D S, Naughton N N. Dosedependent reduction of the minimum local analgesic concentration of bupivacaine by sufentanil for epidural analgesia in labor. Anesthesiology 1998; 89: 626-32. (Pubitemid 28423959)
19. Phillips G. Continuous infusion epidural analgesia in labor: the effect of adding sufentanil to 0.125% bupivacaine. Anesth Analg 1988; 67: 462-5.
20. Vertommen J D, Lemmens E, Van Aken H. Comparison of the addition of three different doses of sufentanil to 0.125% bupivacaine given epidurally during labour. Anaesthesia 1994; 49: 678-81. (Pubitemid 24241012)
21. Columb M O, Lyons G. Determination of the minimum local analgesic concentrations of epidural bupivacaine and lidocaine in labor. Anesth Analg 1995; 81: 833-7.
22. Capogna G, Celleno D, Fusco P, Lyons G, Columb M. Relative potencies of bupivacaine and ropivacaine for analgesia in labour. Br J Anaesth 1999; 82: 371-3. (Pubitemid 29112538)
23. Palm S, Gertzen W, Ledowski T, Gleim M, Wulf H. Minimum local analgesic dose of plain ropivacaine vs ropivacaine combined with sufentanil during epidural analgesia for labour. Anaesthesia 2001; 56: 526-9. (Pubitemid 32529614)
24. Polley L S, Columb M O, Naughton N N, Wagner D S, van de Ven C J. Effect of epidural epinephrine on the minimum local analgesic concentration of epidural bupivacaine in labor. Anesthesiology 2002; 96: 1123-8. (Pubitemid 34462573)
25. Polley L S, Columb M O, Naughton N N, Wagner D S, van de Ven C J M, Goralski K H. Relative analgesic potencies of levobupivacaine and ropivacaine for epidural analgesia in labor. Anesthesiology 2003; 99: 1354-8. (Pubitemid 37475180)
26. Buyse I, Stockman W, Columb M, Vandermeersch E, Van De Velde M. Effect of sufentanil on minimum local analgesic concentrations of epidural bupivacaine, ropivacaine and levobupivacaine in nullipara in early labour. Int J Obstet Anesth 2007; 16: 22-8. (Pubitemid 44909453)
27. Dixon W J, Massey F J. Introduction to statistical analysis. 4th ed. New York: McGraw-Hill, 1983.
28. Lee B B, Ngan KeeWD, Wong E L, Liu J Y. Dose-response study of epidural ropivacaine for labor analgesia. Anesthesiology 2001; 94: 767-72. (Pubitemid 32429745)
29. Van Steenberge A, Debroux H C, Noorduin H. Extradural bupivacaine with sufentanil for vaginal delivery. A double-blind trial. Br J Anaesth 1987; 59: 1518-22. (Pubitemid 18002570)
30. Ledin Eriksson S, Frykholm P, Stenlund P M, Olofsson C. A comparison of three doses of sufentanil in combination with bupivacaine-adrenaline in continuous epidural analgesia during labour. Acta Anaesthesiol Scand 2000; 44: 919-23.
31. Debon R, Allaouchiche B, Duflo F, Boselli E, Chassard D. The analgesic effects of sufentanil combined with ropivacaine 0.2% for labor analgesia: a comparison of three sufentanil doses. Anesth Analg 2001; 92: 180-3. (Pubitemid 32039200)
32. Graft B M, Zauzig Y, Zink W. Current status and clinical relevance of studies of minimum local-anaesthetic concentration (MLAC). Curr Opin Anesthesiol 2005; 18: 241-5. (Pubitemid 40806675)
33. Benhamou D, Mercier F J, Ben Ayed M, Auroy Y. Continuous epidural analgesia with bupivacaine 0.125% or bupivacaine 0.0625% plus sufentanil 0.25 lg/ml: a study in singleton breech presentation. Int J Obstet Anesth 2002; 11: 13-8. (Pubitemid 34130659)
34. Panni M K, Segal S. Local anesthetic requirements are greater in dystocia than in normal labor. Anesthesiology 2003; 98: 957-63. (Pubitemid 36373232)
35. Capogna G, Celleno D, Lyons G, Columb M, Fusco P. Minimum local analgesic concentration of extradural bupivacaine increases with progression of labour. Br J Anaesth 1998; 80: 11-3. (Pubitemid 28029716)
36. Panni M K, Columb M O. Obese parturients have lower epidural local anaesthetic requirements for analgesia in labour. Br J Anaesth 2006; 96: 106-10. (Pubitemid 43124540)
37. Capogna G, Parpaglioni R, Lyons G, Columb M, Celleno D. Minimum analgesic dose of epidural sufentanil for first-stage labor analgesia: a comparison between spontaneous and prostaglandin- induced labors in nulliparous women. Anesthesiology 2001; 94: 740-4. (Pubitemid 32429741)
38. Melzack R. Labour is still painful after prepared childbirth training. Can Med Assoc J 1981; 125: 357-63. (Pubitemid 11000133)
39. Lowe N K. The nature of labor pain. Am J Obstet Gynecol 2002; 186: S16-24. (Pubitemid 34634257)
40. Olayemi O, Adeniji R A, Udoh Es, Aimakhu C O, Shoretire K A. Determinants of pain perception in labour among parturients at the university college hospital, Ibadan. J Obstet Gynaecol 2005; 25: 128-30. (Pubitemid 43323025)
41. Polley L, Columb M, Naughton N, Wagner D. Comparison of the minimum local analgesic concentration of bupivacaine for nulliparous and multiparous women in labor. Anesthesiology 2002; 96(Suppl 1): P-54.
42. Rafati J, Bonhomme V, Dewandre P Y, Hans P, Brichant J F. The minimum local analgesic concentration of ropivacaine in the first stage of labor is similar in primiparas and multiparas. Anesthesiology 2004; 101: A1215.
43. Polley L, Columb M, Naughton N, Wagner D, van de Ven C. Relative analgesic potencies of ropivacaine and bupivacaine for epidural analgesia in labor: implications for therapeutic indexes. Anesthesiology 1999; 90: 944-50. (Pubitemid 29159747)