Resuscitation with the hemoglobin-based oxygen carrier, hboc-201, in a swine model of severe uncontrolled hemorrhage and traumatic brain injury

Shock

Volumn 31, Issue 1, 2009, Pages 64-79

  Stern, Susan ^a,f   Rice, Jennifer ^b   Philbin, Nora ^b   McGwin, Gerald ^c   Arnaud, Francoise ^b   Johnson, Todd ^b   Shannon Flournoy, W ^d   Ahlers, Stephen ^b   Bruce Pearce, L ^e   McCarron, Richard ^b   Freilich, Daniel ^b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b NAVAL MEDICAL RESEARCH CENTER   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^e Biopure Corporation   (United States)

^f UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

HBOC 201; Hemoglobin based oxygen carrier; Hemorrhagic shock; Resuscitation; Traumatic brain injury

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; LACTIC ACID; MICROTUBULE ASSOCIATED PROTEIN; POLYMERIZED HEMOGLOBIN; RINGER LACTATE SOLUTION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEEDING; BLOOD TRANSFUSION; BRAIN BLOOD FLOW; BRAIN OXYGEN TENSION; BRAIN PERFUSION; BRAIN TISSUE; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFICACY; FEMALE; FLUID RESUSCITATION; HEART INDEX; HEMORRHAGIC SHOCK; IMMUNOHISTOCHEMISTRY; LIVER INJURY; MEAN ARTERIAL PRESSURE; MICROSCOPY; NONHUMAN; PERFUSION PRESSURE; SUBARACHNOID HEMORRHAGE; SURVIVAL TIME; SWINE; TRAUMATIC BRAIN INJURY;

ANIMALS; BLOOD FLOW VELOCITY; BLOOD PRESSURE; BLOOD SUBSTITUTES; BRAIN; BRAIN INJURIES; DISEASE MODELS, ANIMAL; FEMALE; HEMOGLOBINS; HEMORRHAGE; HUMANS; ISOTONIC SOLUTIONS; LIVER; LIVER DISEASES; RESUSCITATION; SWINE;

EID: 58849087593     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3181778dc3     Document Type: Article

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