Labisia pumila extract regulates body weight and adipokines in ovariectomized rats

Maturitas

Volumn 62, Issue 1, 2009, Pages 91-97

  Fazliana, Mansor ^a,b   Wan Nazaimoon, W M ^b   Gu, Harvest F ^a   Östenson, Claes Göran ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b Diabetes and Nutrition Research Centre   (Malaysia)

Author keywords

Adipokines; Body weight; Estrogen replacement; Labisia pumila; Ovariectomy

Indexed keywords

ADIPOCYTOKINE; CONJUGATED ESTROGEN; LABISIA PUMILA EXTRACT; LEPTIN; MESSENGER RNA; PLANT EXTRACT; RESISTIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG SYNTHESIS; ESTROGEN THERAPY; FAT BODY; FEMALE; HORMONE BLOOD LEVEL; LABISIA PUMILA; MEDICINAL PLANT; NONHUMAN; OVARIECTOMY; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; UTERUS WEIGHT; WEIGHT GAIN;

ADIPOKINES; ANIMALS; BODY WEIGHT; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTROGEN REPLACEMENT THERAPY; ESTROGENS; ESTROGENS, CONJUGATED (USP); FEMALE; MYRSINACEAE; ORGAN SIZE; OVARIECTOMY; PHYTOTHERAPY; PLANT EXTRACTS; RATS; UTERUS;

ANIMALIA; RATTUS;

EID: 58849087483     PISSN: 03785122     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.maturitas.2008.10.004     Document Type: Article

References (48)

1. Toth M.J., Tchernof A., Sites C.K., and Poehlman E.T. Effect of menopausal status on body composition and abdominal fat distribution. Int J Obes Relat Metab Disord 24 2 (2000) 226-231
2. Tchernof A., Calles-Escandon J., Sites C.K., and Poehlman E.T. Menopause, central body fatness, and insulin resistance: effects of hormone-replacement therapy. Coron Artery 9 8 (1998) 503-511
3. Lobo R.A. Metabolic syndrome after menopause and the role of hormones. Maturitas 60 1 (2008) 10-18
4. Hidaka S., Okamoto Y., and Arita M. A hot water extract of Chlorella pyrenoidosa reduces body weight and serum lipids in ovariectomized rats. Phytother Res 18 2 (2004) 164-168
5. Kim W.H., Park Y.J., Park M.R., et al. Estrogenic effects of Sedum sarmentosum Bunge in ovariectomized rats. J Nutr Sci Vitaminol (Tokyo) 50 2 (2004) 100-105
6. Vasconcellos L.S., Leite J.M., Sabino K.R., and Petroianu A. Influence of oophorectomy on weight variance in young and adult female rats. Arq Bras Endocrinol Metabol 48 2 (2004) 299-304
7. Saruhan B.G., Ozbag D., Gumusalan Y., and Ozdemir N. Influence of ovariectomy and flutamide treatment on vaginal tissue and body weight. Saudi Med J 26 12 (2005) 1897-1903
8. Roesch D.M. Effects of selective estrogen receptor agonists on food intake and body weight gain in rats. Physiol Behav 87 1 (2006) 39-44
9. Sanchez-Mateos S., Alonso-Gonzalez C., Gonzalez A., et al. Melatonin and estradiol effects on food intake, body weight, and leptin in ovariectomized rats. Maturitas 58 1 (2007) 91-101
10. Shinoda M., Latour M.G., and Lavoie J.M. Effects of physical training on body composition and organ weights in ovariectomized and hyperestrogenic rats. Int J Obes Relat Metab Disord 26 3 (2002) 335-343
11. Rachoń D., Vortherms T., Seidlová-Wuttke D., Menche A., and Wuttke W. Uterotropic effects of dietary equol administration in ovariectomized Sprague-Dawley rats. Climacteric 10 5 (2007) 416-426
12. D'Eon T.M., Souza S.C., Aronovitz M., Obin M.S., Fried S.K., and Greenberg A.S. Estrogen regulation of adiposity and fuel partitioning. Evidence of genomic and non-genomic regulation of lipogenic and oxidative pathways. J Biol Chem 280 43 (2005) 35983-35991
13. Burkill IH. A dictionary of the economic products of the Malay peninsula, vol. II (I-Z). 4 Millbank, London, S.W. 1: Publisher Crown Agents for the Colonies; 1935. p. 1290
14. Stone BC. Notes on the genus Labisia Lindl. (Myrsinaceae). Malayan Nat J 1988;42(1):43-51.
15. Zakaria M, Mohd MA. Traditional Malay medicinal plants. Kuala Lumpur: Penerbit Fajar Bakti Sdn. Bhd; 1994.
16. Husniza H. Estrogenic and androgenic activities of kacip fatimah (Labisia pumila). Abstracts of Research Project. Kuala Lumpur: Institute for Medical Research, Ministry of Health Malaysia; 2002. p. 8.
17. Fonseca-Alaniz M.H., Takada J., Alonso-Vale M.I., and Lima F.B. Adipose tissue as an endocrine organ: from theory to practice. J Pediatr (Rio J) 83 5 Suppl. (2007) S192-203
18. Matsuzawa Y. White adipose tissue and cardiovascular disease. Best Pract Res Clin Endocrinol Metab 4 (2005) 637-647
19. Tanaka M., Nakaya S., Kumai T., et al. Effects of estrogen on serum leptin levels and leptin mRNA expression in adipose tissue in rats. Horm Res 56 3-4 (2001) 98-104
20. Zhang Y., Proenca R., Maffei M., Barone M., Leopold L., and Friedman J.M. Positional cloning of the mouse obese gene and its human homologue. Nature 372 6505 (1994) 425-432
21. Saad M.F., Damani S., Gingerich R.L., et al. Sexual dimorphism in plasma leptin concentration. J Clin Endocrinol Metab 82 2 (1997) 579-584
22. Steppan C.M., Bailey S.T., Bhat S., et al. The hormone resistin links obesity to diabetes. Nature 409 6818 (2001) 307-312
23. McTernan P.G., McTernan C.L., Chetty R., et al. Increased resistin gene and protein expression in human abdominal adipose tissue. J Clin Endocrinol Metab 87 5 (2002) 2407
24. Machinal F., Dieudonne M.N., Leneveu M.C., Pecquery R., and Giudicelli Y. In vivo and in vitro ob gene expression and leptin secretion in rat adipocytes: evidence for a regional specific regulation by sex steroid hormones. Endocrinology 140 (1999) 1567-1574
25. Lu J.Y., Huang K.C., Chang L.C., et al. Adiponectin: a biomarker of obesity-induced insulin resistance in adipose tissue and beyond. J Biomed Sci 15 5 (2008) 565-576
26. Maeda N., Shimomura I., Kishida K., et al. Diet-induced insulin resistance in mice lacking adiponectin/ACRP30. Nat Med 8 7 (2002) 731-737
27. Ayida A.-Wahabi., Wan Nazaimoon W.M., Farihah H.S., and Azian A.L. Effect of ovariectomy, Labisia pumila var alata treatment and estrogen replacement therapy on the morphology of adipose tissue in ovariectomized Sprague Dawley rats. J Med Biol Sci 1 1 (2006)
28. Sivan E., Whittaker P.G., Sinha D., et al. Leptin in human pregnancy: the relationship with gestational hormones. Am J Obstet Gynecol 179 5 (1998) 1128-1132
29. Alonso A., Fernández R., Moreno M., Ordóñez P., Díaz F., and González C. Leptin and its receptor are controlled by 17beta-estradiol in peripheral tissues of ovariectomized rats. Exp Biol Med (Maywood) 232 4 (2007) 542-549
30. Gorzek J.F., Hendrickson K.C., Forstner J.P., Rixen J.L., Moran A.L., and Lowe D.A. Estradiol and tamoxifen reverse ovariectomy-induced physical inactivity in mice. Med Sci Sports Exerc 39 2 (2007) 248-256
31. Kishida T., Mizushige T., Ohtsu Y., et al. Dietary soy isoflavone-aglycone lowers food intake in female rats with and without ovariectomy. Obesity (Silver Spring) 16 2 (2008) 290-297
32. González C., Alonso A., Grueso N.A., Esteban M.M., Fernández S., and Patterson A.M. Effect of treatment with different doses of 17-beta-estradiol on the insulin receptor. Life Sci 70 14 (2002) 1621-1630
33. González C., Alonso A., Díaz F., and Patterson A.M. Dose- and time-dependent effects of 17beta-oestradiol on insulin sensitivity in insulin-dependent tissues of rat: implications of IRS-1. J Endocrinol 176 3 (2003) 367-379
34. Korinac G., Milosavljevic T., Stojiljkovic M., Zakula Z., Ribarac-Stepic N., and Isenovic E.R. Insulin signaling in the liver and uterus of ovariectomized rats treated with estradiol. J Steroid Biochem Mol Biol 108 1-2 (2008) 109-116
35. García-Pérez M.A., Del Val R., Noguera I., et al. Estrogen receptor agonists and immune system in ovariectomized mice. Int J Immunopathol Pharmacol 19 4 (2006) 807-819
36. Yoneda N., Saito S., Kimura M., et al. The influence of ovariectomy on ob gene expression in rats. Horm Metab Res 30 5 (1998) 263-265
37. Kristensen K., Pedersen S.B., and Richelsen B. Regulation of leptin by steroid hormones in rat adipose tissue. Biochem Biophys Res Commun 259 3 (1999) 624-630
38. Wu-Peng S., Rosenbaum M., Nicolson M., Chua S.C., and Leibel R.L. Effects of exogenous gonadal steroids on leptin homeostasis in rats. Obes Res 7 6 (1999) 586-592
39. Hozumi Y., Hakamata Y., and Nagai H. Plasma leptin concentration in tamoxifen-treated ovariectomized rats. Gynecol Obstet Invest 59 2 (2005) 70-74
40. Meli R., Pacilio M., Raso G.M., et al. Estrogen and raloxifene modulate leptin and its receptor in hypothalamus and adipose tissue from ovariectomized rats. Endocrinology 145 7 (2004) 3115-3121
41. Seidlová-Wuttke D., Christoffel J., Rimoldi G., Jarry H., and Wuttke W. Comparison of effects of estradiol with those of octylmethoxycinnamate and 4-methylbenzylidene camphor on fat tissue, lipids and pituitary hormones. Toxicol Appl Pharmacol 214 1 (2006) 1-7
42. Brann D.W., De Sevilla L., Zamorano P.L., and Mahesh V.B. Regulation of leptin gene expression and secretion by steroid hormones. Steroids 64 9 (1999) 659-663
43. Kimura M., Irahara M., Yasui T., et al. The obesity in bilateral ovariectomized rats is related to a decrease in the expression of leptin receptors in the brain. Biochem Biophys Res Commun 290 (2002) 1349-1353
44. Huang S.W., Seow K.M., Ho L.T., et al. Resistin mRNA levels are downregulated by estrogen in vivo and in vitro. FEBS Lett 579 2 (2005) 449-454
45. Gui Y., Silha J.V., and Murphy L.J. Sexual dimorphism and regulation of resistin, adiponectin, and leptin expression in the mouse. Obes Res 12 9 (2004) 1481-1491
46. Chen Y.H., Lee M.J., Chang H.H., Hung P.F., and Kao Y.H. 17 beta-estradiol stimulates resistin gene expression in 3T3-L1 adipocytes via the estrogen receptor, extracellularly regulated kinase, and CCAAT/enhancer binding protein-aLPvaha pathways. Endocrinology 147 9 (2006) 4496-4504
47. Nishizawa H., Shimomura I., Kishida K., et al. Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein. Diabetes 51 9 (2002) 2734-2741
48. Chalvatzas N, Dafopoulos K, Kosmas G, Kallitsaris A, Pournaras S, Messinis IE. Effect of ovarian hormones on serum adiponectin and resistin concentrations. Fertil Steril 2008 Mar 4. [Epub ahead of print].