Comparison of effects of estradiol with those of octylmethoxycinnamate and 4-methylbenzylidene camphor on fat tissue, lipids and pituitary hormones

Toxicology and Applied Pharmacology

Volumn 214, Issue 1, 2006, Pages 1-7

  Seidlová Wuttke, Dana ^a   Christoffel, Julie ^a   Rimoldi, Guillermo ^a   Jarry, Hubertus ^a   Wuttke, Wolfgang ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

4MBC; Estradiol; Lipids; OMC; Pituitary hormones

Indexed keywords

4 METHYLBENZYLIDENE CAMPHOR; CHOLESTEROL; ENDOCRINE DISRUPTOR; ESTRADIOL; HYPOPHYSIS HORMONE; LEPTIN; LIPID; LOW DENSITY LIPOPROTEIN; OCTYLMETHOXYCINNAMATE; THYROID HORMONE; THYROTROPIN; THYROXINE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ESTROGEN ACTIVITY; FEMALE; HOMEOSTASIS; HORMONE BLOOD LEVEL; HORMONE SYNTHESIS; LIPID STORAGE; METABOLIC PARAMETERS; NONHUMAN; OVARIECTOMY; PROTEIN BLOOD LEVEL; RAT; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL; TRIACYLGLYCEROL BLOOD LEVEL; ULTRAVIOLET RADIATION; ULTRAVIOLET SPECTROSCOPY; UTERUS; WEIGHT GAIN;

ADIPOSE TISSUE; ANIMALS; CAMPHOR; CINNAMATES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCRINE DISRUPTORS; ESTRADIOL; FEMALE; LEPTIN; LIPIDS; OVARIECTOMY; PITUITARY HORMONES; RATS; RATS, SPRAGUE-DAWLEY; THYROXINE; UTERUS;

ANIMALIA; DRYOBALANOPS;

EID: 33744985283     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2005.11.002     Document Type: Article

References (34)

1. Albertazzi P., and Purdie D.W. The life and times of the estrogen receptors: an interim report. Climacteric 4 (2001) 194-202
2. Anwar A., McTernan P.G., Anderson L.A., Askaa J., Moody C.G., Barnett A.H., Eggo M.C., and Kumar S. Site-specific regulation of oestrogen receptor-alpha and -beta by oestradiol in human adipose tissue. Diabetes Obes. Metab. 3 (2001) 338-349
3. Boado R., Ulloa E., and Zaninovich A.A. Effects of oestradiol benzoate on the pituitary-thyroid axis of male and female rats. Acta. Endocrinol. (Copenh) 102 (1983) 386-391
4. Caltagirone S., Ranelletti F.O., Rinelli A., Maggiano N., Colasante A., Musiani P., Aiello F.B., and Piantelli M. Interaction with type II estrogen binding sites and antiproliferative activity of tamoxifen and quercetin in human non-small-cell lung cancer. Am. J. Respir. Cell Mol. Biol. 17 (1997) 51-59
5. Couse J.F., and Korach K.S. Contrasting phenotypes in reproductive tissues of female estrogen receptor null mice. Ann. N. Y. Acad. Sci. 948 (2001) 1-8
6. Evans N.P., Richter T.A., Skinner D.C., and Robinson J.E. Neuroendocrine mechanisms underlying the effects of progesterone on the oestradiol-induced GnRH/LH surge. Reprod., Suppl. 59 (2002) 57-66
7. Franklyn J.A., Wood D.F., Balfour N.J., Ramsden D.B., Docherty K., and Sheppard M.C. Modulation by oestrogen of thyroid hormone effects on thyrotrophin gene expression. J. Endocrinol. 115 (1987) 53-59
8. Ginci G., Arezzini L., Terzuoli L., Pizzichini M., and Marinello E. Effect of estradiol on serum triglyceride lipoprotein levels and fatty acid composition in castrated rats. Horm. Metab. Res. 29 (1997) 504-506
9. Holbech H., Norum U., Korsgaard B., and Poul B. The chemical UV-filter 3-benzylidene camphor causes an oestrogenic effect in an in vivo fish assay. Pharmacol. Toxicol. 91 (2002) 204-208
10. Inui M., Adachi T., Takenaka S., Inui H., Nakazawa M., Ueda M., Watanabe H., Mori C., Iguchi T., and Miyatake K. Effect of UV screens and preservatives on vitellogenin and choriogenin production in male medaka (Oryzias latipes). Toxicology 194 (2003) 43-50
11. Jacobson K.A., Moro S., Manthey J.A., West P.L., and Ji X.D. Interactions of flavones and other phytochemicals with adenosine receptors. Adv. Exp. Med. Biol. 505 (2002) 163-171
12. Janjua N.R., Mogensen B., Andersson A.M., Petersen J.H., Henriksen M., Skakkebaek N.E., and Wulf H.C. Systemic absorption of the sunscreens benzophenone-3, octyl-methoxycinnamate, and 3-(4-methyl-benzylidene) camphor after whole-body topical application and reproductive hormone levels in humans. J. Invest. Dermatol. 123 (2004) 57-61
13. Jarry H., Metten M., Spengler B., Christoffel V., and Wuttke W. In vitro effects of the Cimicifuga racemosa extract BNO 1055. Maturitas 44 Suppl. 1 (2003) S31-S38
14. Joyner J.M., Hutley L.J., and Cameron D.P. Estrogen receptors in human preadipocytes. Endocrine 15 (2001) 225-230
15. Katzenellenbogen B.S., Sun J., Harrington W.R., Kraichely D.M., Ganessunker D., and Katzenellenbogen J.A. Structure-function relationships in estrogen receptors and the characterization of novel selective estrogen receptor modulators with unique pharmacological profiles. Ann. N. Y. Acad. Sci. 949 (2001) 6-15
16. Korach K.S., Emmen J.M., Walker V.R., Hewitt S.C., Yates M., Hall J.M., Swope D.L., Harrell J.C., and Couse J.F. Update on animal models developed for analyses of estrogen receptor biological activity. J. Steroid Biochem. Mol. Biol. 86 (2003) 387-391
17. Kuiper G.G., Carlsson B., Grandien K., Enmark E., Haggblad J., Nilsson S., and Gustafsson J.A. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology 138 (1997) 863-870
18. Lisboa P.C., Curty F.H., Moreira R.M., and Pazos-Moura C.C. Effects of estradiol benzoate on 5′-iodothyronine deiodinase activities in female rat anterior pituitary gland, liver and thyroid gland. Braz. J. Med. Biol. Res. 30 (1997) 1479-1484
19. Ma R., Cotton B., Lichtensteiger W., and Schlumpf M. UV filters with antagonistic action at androgen receptors in the MDA-kb2 cell transcriptional-activation assay. Toxicol. Sci. 74 (2003) 43-50
20. Maffei M., Halaas J., Ravussin E., Pratley R.E., Lee G.H., Zhang Y., Fei H., Kim S., Lallone R., Ranganathan S., et al. Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat. Med. 1 (1995) 1155-1161
21. Markaverich B.M., Roberts R.R., Alejandro M.A., Johnson G.A., Middleditch B.S., and Clark J.H. Bioflavonoid interaction with rat uterine type II binding sites and cell growth inhibition. J. Steroid. Biochem. 30 (1988) 71-78
22. Meli R., Pacilio M., Raso G.M., Esposito E., Coppola A., Nasti A., Di Carlo C., Nappi C., and Di Carlo R. Estrogen and raloxifene modulate leptin and its receptor in hypothalamus and adipose tissue from ovariectomized rats. Endocrinology 145 (2004) 3115-3121
23. Misso M.L., Murata Y., Boon W.C., Jones M.E., Britt K.L., and Simpson E.R. Cellular and molecular characterization of the adipose phenotype of the aromatase-deficient mouse. Endocrinology 144 (2003) 1474-1480
24. Mueller S.O., Kling M., Arifin Firzani P., Mecky A., Duranti E., Shields-Botella J., Delansorne R., Broschard T., and Kramer P.J. Activation of estrogen receptor alpha and ERbeta by 4-methylbenzylidene-camphor in human and rat cells: comparison with phyto- and xenoestrogens. Toxicol. Lett. 142 (2003) 89-101
25. Nilsson S., Makela S., Treuter E., Tujague M., Thomsen J., Andersson G., Enmark E., Pettersson K., Warner M., and Gustafsson J.A. Mechanisms of estrogen action. Physiol. Rev. 81 (2001) 1535-1565
26. Palin S.L., McTernan P.G., Anderson L.A., Sturdee D.W., Barnett A.H., and Kumar S. 17Beta-estradiol and anti-estrogen ICI: compound 182,780 regulate expression of lipoprotein lipase and hormone-sensitive lipase in isolated subcutaneous abdominal adipocytes. Metabolism 52 (2003) 383-388
27. Parini P., Angelin B., Stavreus-Evers A., Freyschuss B., Eriksson H., and Rudling M. Biphasic effects of the natural estrogen 17beta-estradiol on hepatic cholesterol metabolism in intact female rats. Arterioscler. Thromb. Vasc. Biol. 20 (2000) 1817-1823
28. Schlumpf M., Cotton B., Conscience M., Haller V., Steinmann B., and Lichtensteiger W. In vitro and in vivo estrogenicity of UV screens. Environ. Health Perspect. 109 (2001) 239-244
29. Schlumpf M., Jarry H., Wuttke W., Ma R., and Lichtensteiger W. Estrogenic activity and estrogen receptor beta binding of the UV filter 3-benzylidene camphor. Comparison with 4-methylbenzylidene camphor. Toxicology 199 (2004) 109-120
30. Seidlova-Wuttke D., Becker T., Christoffel V., Jarry H., and Wuttke W. Silymarin is a selective estrogen receptor beta (ERbeta) agonist and has estrogenic effects in the metaphysis of the femur but no or antiestrogenic effects in the uterus of ovariectomized (ovx) rats. J. Steroid Biochem. Mol. Biol. 86 (2003) 179-188
31. Seidlova-Wuttke D., Jarry H., Becker T., Christoffel V., and Wuttke W. Pharmacology of Cimicifuga racemosa extract BNO 1055 in rats: bone, fat and uterus. Maturitas 44 Suppl. 1 (2003) S39-S50
32. Suetsugi M., Su L., Karlsberg K., Yuan Y.C., and Chen S. Flavone and isoflavone phytoestrogens are agonists of estrogen-related receptors. Mol. Cancer Res. 1 (2003) 981-991
33. Thomas D.K., Storlien L.H., Bellingham W.P., and Gillette K. Ovarian hormone effects on activity, glucoregulation and thyroid hormones in the rat. Physiol. Behav. 36 (1986) 567-573
34. Tinwell H., Lefevre P.A., Moffat G.J., Burns A., Odum J., Spurway T.D., Orphanides G., and Ashby J. Confirmation of uterotrophic activity of 3-(4-methylbenzylidine)camphor in the immature rat. Environ. Health Perspect. 110 (2002) 533-536