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Volumn 56, Issue 4, 2008, Pages 399-404

Platelet glycoprotein IIb/IIIa inhibitors in acute ischemic stroke

Author keywords

Abciximab; Acute ischemic stroke; Cerebrovascular disease; Platelet glycoprotein IIb IIIa inhibitors; Tirofiban

Indexed keywords

ABCIXIMAB; ALTEPLASE; FIBRINOGEN RECEPTOR; HEPARIN; PLACEBO; TIROFIBAN; UROKINASE; VITRONECTIN RECEPTOR;

EID: 58749107885     PISSN: 00283886     EISSN: 19984022     Source Type: Journal    
DOI: 10.4103/0028-3886.44571     Document Type: Review
Times cited : (7)

References (29)
  • 3
    • 0025201050 scopus 로고
    • Subtypes and proportions of cerebrovascular disease in an autopsy series in a Japanese geriatric hospital
    • Yamanouchi H, Shimada H, Kuramoto K. Subtypes and proportions of cerebrovascular disease in an autopsy series in a Japanese geriatric hospital. Klin Wochenschr 1990;68:1173-7.
    • (1990) Klin Wochenschr , vol.68 , pp. 1173-1177
    • Yamanouchi, H.1    Shimada, H.2    Kuramoto, K.3
  • 5
    • 33746876034 scopus 로고    scopus 로고
    • Thrombolytic therapy in acute ischemic stroke in Asia: The first prospective evaluation
    • Suwanwela NC, Phanthumchinda K, Likitjaroen Y. Thrombolytic therapy in acute ischemic stroke in Asia: The first prospective evaluation. Clin Neurol Neurosurg 2006;108:549-52.
    • (2006) Clin Neurol Neurosurg , vol.108 , pp. 549-552
    • Suwanwela, N.C.1    Phanthumchinda, K.2    Likitjaroen, Y.3
  • 7
    • 58749098122 scopus 로고    scopus 로고
    • Platelet glycoprotein IIb/IIIa receptor inhibitors-role in coronary artery disease
    • Neki NS. Platelet glycoprotein IIb/IIIa receptor inhibitors-role in coronary artery disease. J Indian Acad Community Med 2004;5:259-65.
    • (2004) J Indian Acad Community Med , vol.5 , pp. 259-265
    • Neki, N.S.1
  • 8
    • 0032566404 scopus 로고    scopus 로고
    • Randomized, placebo-controlled trial of platelet glycoprotein IIb/IIIa blockade with primary angioplasty for acute myocardial infarction
    • Brener SJ, Barr LA, Burchenal JE, Katz S, George BS, Jones AA, et al. Randomized, placebo-controlled trial of platelet glycoprotein IIb/IIIa blockade with primary angioplasty for acute myocardial infarction. Circulation 1998;98:734-41.
    • (1998) Circulation , vol.98 , pp. 734-741
    • Brener, S.J.1    Barr, L.A.2    Burchenal, J.E.3    Katz, S.4    George, B.S.5    Jones, A.A.6
  • 9
    • 0008926519 scopus 로고    scopus 로고
    • Inhibition of platelet glycoprotein IIb/IIIa with eptifibatide in patients with acute coronary syndromes
    • The PURSUIT Trial Investigators
    • The PURSUIT Trial Investigators. Inhibition of platelet glycoprotein IIb/IIIa with eptifibatide in patients with acute coronary syndromes. N Engl J Med 1998; 339:436-43.
    • (1998) N Engl J Med , vol.339 , pp. 436-443
  • 10
    • 0342514814 scopus 로고    scopus 로고
    • Abciximab in acute ischemic stroke: A randomized, double-blind, placebo-controlled, dose-escalation study
    • The Abciximab in Ischemic Stroke Investigators
    • The Abciximab in Ischemic Stroke Investigators. Abciximab in acute ischemic stroke: A randomized, double-blind, placebo-controlled, dose-escalation study. Stroke 2000;31:601-9.
    • (2000) Stroke , vol.31 , pp. 601-609
  • 11
    • 23844543072 scopus 로고    scopus 로고
    • MRI-guided, open trial of abciximab for ischemic stroke within a 3- to 24-hour window
    • Mitsias PD, Lu M, Silver B, Morris D, Ewing JR, Daley S, et al. MRI-guided, open trial of abciximab for ischemic stroke within a 3- to 24-hour window. Neurology 2005;65:612-5.
    • (2005) Neurology , vol.65 , pp. 612-615
    • Mitsias, P.D.1    Lu, M.2    Silver, B.3    Morris, D.4    Ewing, J.R.5    Daley, S.6
  • 12
    • 33646096747 scopus 로고    scopus 로고
    • MRI-guided, open trial of abciximab for ischemic stroke within a 3- to 24-hour window
    • Mandava P, Anderson JA, Kent TA. MRI-guided, open trial of abciximab for ischemic stroke within a 3- to 24-hour window. Neurology 2006;66:1132.
    • (2006) Neurology , vol.66 , pp. 1132
    • Mandava, P.1    Anderson, J.A.2    Kent, T.A.3
  • 13
    • 0347383750 scopus 로고    scopus 로고
    • Treatment of acute stroke with recombinant tissue plasminogen activator and abciximab
    • Morris DC, Silver B, Mitsias P, Lewandowski C, Patel S, Daley S, et al. Treatment of acute stroke with recombinant tissue plasminogen activator and abciximab. Acad Emerg Med 2003;10:1396-9.
    • (2003) Acad Emerg Med , vol.10 , pp. 1396-1399
    • Morris, D.C.1    Silver, B.2    Mitsias, P.3    Lewandowski, C.4    Patel, S.5    Daley, S.6
  • 14
    • 20444428287 scopus 로고    scopus 로고
    • Aggressive therapy with intravenous abciximab and intra-arterial rtPA and additional PTA/stenting improves clinical outcome in acute vertebrobasilar occlusion: Combined local fibrinolysis and intravenous abciximab in acute vertebrobasilar stroke treatment (FAST): Results of a multicenter study
    • Eckert B, Koch C, Thomalla G, Kucinski T, Grzyska U, Roether J, et al. Aggressive therapy with intravenous abciximab and intra-arterial rtPA and additional PTA/stenting improves clinical outcome in acute vertebrobasilar occlusion: Combined local fibrinolysis and intravenous abciximab in acute vertebrobasilar stroke treatment (FAST): Results of a multicenter study. Stroke 2005;36:1160-5.
    • (2005) Stroke , vol.36 , pp. 1160-1165
    • Eckert, B.1    Koch, C.2    Thomalla, G.3    Kucinski, T.4    Grzyska, U.5    Roether, J.6
  • 15
    • 0037799475 scopus 로고    scopus 로고
    • Immediate reocclusion following a successful thrombolysis in acute stroke: A pilot study
    • Heo JH, Lee KY, Kim SH, Kim DI. Immediate reocclusion following a successful thrombolysis in acute stroke: A pilot study. Neurology 2003;60:1684-7.
    • (2003) Neurology , vol.60 , pp. 1684-1687
    • Heo, J.H.1    Lee, K.Y.2    Kim, S.H.3    Kim, D.I.4
  • 16
    • 33644911452 scopus 로고    scopus 로고
    • The use of abciximab in the treatment of acute cerebral thromboembolic events during neuroendovascular procedures
    • discussion 358-9
    • Velat GJ, Burry MV, Eskioglu E, Dettorre RR, Firment CS, Mericle RA. The use of abciximab in the treatment of acute cerebral thromboembolic events during neuroendovascular procedures. Surg Neurol 2006;65:352-8, discussion 358-9.
    • (2006) Surg Neurol , vol.65 , pp. 352-358
    • Velat, G.J.1    Burry, M.V.2    Eskioglu, E.3    Dettorre, R.R.4    Firment, C.S.5    Mericle, R.A.6
  • 18
    • 16844383611 scopus 로고    scopus 로고
    • Emergency administration of abciximab for treatment of patients with acute ischemic stroke: Results of a randomized phase 2 trial
    • Abciximab Emergent Stroke Treatment Trial (AbESTT) Investigators
    • Abciximab Emergent Stroke Treatment Trial (AbESTT) Investigators. Emergency administration of abciximab for treatment of patients with acute ischemic stroke: results of a randomized phase 2 trial. Stroke 2005;36:880-90.
    • (2005) Stroke , vol.36 , pp. 880-890
  • 19
    • 38149053126 scopus 로고    scopus 로고
    • Emergency administration of abciximab for treatment of patients with acute ischemic stroke: Results of an international phase III trial: Abciximab in Emergency Treatment of Stroke Trial (AbESTT-II)
    • Adams HP Jr, Effron MB, Torner J, Frayne J, Teal P, Leclerc J, et al. Emergency administration of abciximab for treatment of patients with acute ischemic stroke: Results of an international phase III trial: Abciximab in Emergency Treatment of Stroke Trial (AbESTT-II). Stroke 2008;39:87-99.
    • (2008) Stroke , vol.39 , pp. 87-99
    • Adams Jr, H.P.1    Effron, M.B.2    Torner, J.3    Frayne, J.4    Teal, P.5    Leclerc, J.6
  • 20
    • 0035195619 scopus 로고    scopus 로고
    • Bleeding risk of tirofiban: A nonpeptide GPIIb/IIIa platelet receptor antagonist in progressive stroke: An open pilot study
    • Junghans U, Seitz RJ, Aulich A, Freund HJ, Siebler M. Bleeding risk of tirofiban: A nonpeptide GPIIb/IIIa platelet receptor antagonist in progressive stroke: An open pilot study. Cerebrovasc Dis 2001;12:308-12.
    • (2001) Cerebrovasc Dis , vol.12 , pp. 308-312
    • Junghans, U.1    Seitz, R.J.2    Aulich, A.3    Freund, H.J.4    Siebler, M.5
  • 21
    • 1442274797 scopus 로고    scopus 로고
    • Systemic thrombolysis with recombinant tissue plasminogen activator and tirofiban in acute middle cerebral artery occlusion
    • Straub S, Junghans U, Jovanovic V, Wittsack HJ, Seitz RJ, Siebler M. Systemic thrombolysis with recombinant tissue plasminogen activator and tirofiban in acute middle cerebral artery occlusion. Stroke 2004;35:705-9.
    • (2004) Stroke , vol.35 , pp. 705-709
    • Straub, S.1    Junghans, U.2    Jovanovic, V.3    Wittsack, H.J.4    Seitz, R.J.5    Siebler, M.6
  • 22
    • 0042122432 scopus 로고    scopus 로고
    • Thrombolysis with recombinant tissue plasminogen activator and tirofiban in stroke: Preliminary observations
    • Seitz RJ, Hamzavi M, Junghans U, Ringleb PA, Schranz C, Siebler M. Thrombolysis with recombinant tissue plasminogen activator and tirofiban in stroke: Preliminary observations. Stroke 2003;34:1932-5.
    • (2003) Stroke , vol.34 , pp. 1932-1935
    • Seitz, R.J.1    Hamzavi, M.2    Junghans, U.3    Ringleb, P.A.4    Schranz, C.5    Siebler, M.6
  • 23
    • 33644842907 scopus 로고    scopus 로고
    • Intravenous glycoprotein IIb/IIIa inhibitor (tirofiban) followed by intra-arterial urokinase and mechanical thrombolysis in stroke
    • Mangiafico S, Cellerini M, Nencini P, Gensini G, Inzitari D. Intravenous glycoprotein IIb/IIIa inhibitor (tirofiban) followed by intra-arterial urokinase and mechanical thrombolysis in stroke. AJNR Am J Neuroradiol 2005;26:2595-601.
    • (2005) AJNR Am J Neuroradiol , vol.26 , pp. 2595-2601
    • Mangiafico, S.1    Cellerini, M.2    Nencini, P.3    Gensini, G.4    Inzitari, D.5
  • 25
    • 0035181196 scopus 로고    scopus 로고
    • Treatment of acute basilar artery thrombosis with a combination of systemic alteplase and tirofiban, a nonpeptide platelet glycoprotein IIb/IIIa inhibitor: Report of four cases
    • Junghans U, Seitz RJ, Wittsack HJ, Aulich A, Siebler M. Treatment of acute basilar artery thrombosis with a combination of systemic alteplase and tirofiban, a nonpeptide platelet glycoprotein IIb/IIIa inhibitor: Report of four cases. Radiology 2001;221:795-801.
    • (2001) Radiology , vol.221 , pp. 795-801
    • Junghans, U.1    Seitz, R.J.2    Wittsack, H.J.3    Aulich, A.4    Siebler, M.5
  • 26
    • 0037065834 scopus 로고    scopus 로고
    • Ischemic brain tissue salvaged from infarction by the GP IIb/IIIa platelet antagonist tirofiban
    • Junghans U, Seitz RJ, Ritzl A, Wittsack HJ, Fink GR, Freund HJ, et al. Ischemic brain tissue salvaged from infarction by the GP IIb/IIIa platelet antagonist tirofiban. Neurology 2002;58:474-6.
    • (2002) Neurology , vol.58 , pp. 474-476
    • Junghans, U.1    Seitz, R.J.2    Ritzl, A.3    Wittsack, H.J.4    Fink, G.R.5    Freund, H.J.6
  • 27
    • 2942618974 scopus 로고    scopus 로고
    • The effect of combined thrombolysis with rtPA and tirofiban on ischemic brain lesions
    • Seitz RJ, Meisel S, Moll M, Wittsack HJ, Junghans U, Siebler M. The effect of combined thrombolysis with rtPA and tirofiban on ischemic brain lesions. Neurology 2004;62:2110-2.
    • (2004) Neurology , vol.62 , pp. 2110-2112
    • Seitz, R.J.1    Meisel, S.2    Moll, M.3    Wittsack, H.J.4    Junghans, U.5    Siebler, M.6
  • 28
    • 0038580661 scopus 로고    scopus 로고
    • Cerebral microembolism is blocked by tirofiban: A selective nonpeptide platelet glycoprotein IIb/IIIa receptor antagonist
    • Junghans U, Siebler M. Cerebral microembolism is blocked by tirofiban: A selective nonpeptide platelet glycoprotein IIb/IIIa receptor antagonist. Circulation 2003;107:2717-21.
    • (2003) Circulation , vol.107 , pp. 2717-2721
    • Junghans, U.1    Siebler, M.2
  • 29
    • 58749084374 scopus 로고    scopus 로고
    • Available from:, last accessed on 2008 Jun 7
    • Available from: http://www.docguide.com/news/content.nsf/news/ 852571020057CCF685257178005861A6. [last accessed on 2008 Jun 7].


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.