The effect of combined thrombolysis with rtPA and tirofiban on ischemic brain lesions

Neurology

Volumn 62, Issue 11, 2004, Pages 2110-2112

  Seitz, Rüiger J ^a,b   Meisel, S ^a   Moll, M ^a   Wittsack, H J ^a   Junghans, U ^a   Siebler, M ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALTEPLASE; HEPARIN; TIROFIBAN;

ADULT; AGED; ARTICLE; BLOOD CLOT LYSIS; BRAIN ISCHEMIA; BRAIN PERFUSION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTINUOUS INFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIFFUSION; DRUG EFFECT; FEMALE; HUMAN; IMAGE ANALYSIS; MALE; NEUROLOGIC DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; OPEN STUDY; PRIORITY JOURNAL; TREATMENT OUTCOME; VOLUMETRY;

EID: 2942618974     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.WNL.0000129480.17345.4A     Document Type: Article

References (11)

1. Seitz RJ, Hamzawi M, Junghans U, et al. Thrombolysis with rtPA and tirofiban in acute stroke: a pilot study. Stroke 2003;34:1932-1935.
2. Kulkarni S, Dopheide SM, Yap CL, et al. A revised model of platelet aggregation. J Clin Invest 2000;105:783-791.
3. Junghans U, Seitz RJ, Aulich A, et al. Bleeding risk of tirofiban, a nonpeptide GPI//IIIa platelet receptor antagonist in progressive stroke: an open pilot study. Cerebrovasc Dis 2001;12:1-5.
4. Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms (PRISM-PLUS) Study Investigators. Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non-Q-wave myocardial infarction [erratum in N Engl J Med 1998;339: 415]. N Engl J Med 1998;338: 1488-1497.
5. Platelet Receptor Inhibition in Ischemic Syndrome Management in Patients Limited by Unstable Signs and Symptoms (PRISM-PLUS) Study Investigators. Inhibition of the platelet glycoprotein IIb/IIIa receptor with tirofiban in unstable angina and non-Q-wave myocardial infarction [erratum in N Engl J Med 1998;339: 415]. N Engl J Med 1998;338: 1488-1497.
6. Wittsack HJ, Ritzl A, Fink GR, et al. MR imaging in acute stroke: diffusion-weighted and perfusion imaging parameters for predicting infarct size. Radiology 2002;222:397-403.
7. Ostergaard L, Sorensen AG, Kwong KK, et al. High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part II: experimental comparison and preliminary results. Magn Reson Med 1996;36:726-736.
8. Rother J, Schellinger PD, Gass A, et al. Effect of intravenous thrombolysis on MRI parameters and functional outcome in acute stroke <6 hours. Stroke 2002;33:2438-2445.
9. Parsons MW, Barber PA, Chalk J, et al. Diffusion- and perfusion-weighted MRI response to thrombolysis in stroke. Ann Neurol 2002;51: 28-37.
10. Kidwell CS, Saver JL, Starkman S, et al. Late secondary ischemic injury in patients receiving intraarterial thrombolysis. Ann Neurol 2002;52:698-703.
11. Hantson L, De Weerdt W, De Keyser J, et al. The European Stroke Scale. Stroke 1994;25:2215-2219.