-
1
-
-
0031856408
-
IL-6 functions in cynomolgus monkeys blocked by a humanized antibody to human IL-6 receptor
-
Imazeki I., Saito H., Hasegawa M., Shinkura H., Kishimoto T., and Ohsugi Y. IL-6 functions in cynomolgus monkeys blocked by a humanized antibody to human IL-6 receptor. Int. J. Immunopharmacol. 20 (1998) 345-357
-
(1998)
Int. J. Immunopharmacol.
, vol.20
, pp. 345-357
-
-
Imazeki, I.1
Saito, H.2
Hasegawa, M.3
Shinkura, H.4
Kishimoto, T.5
Ohsugi, Y.6
-
2
-
-
0037064550
-
The role of transsignalling via the agonistic soluble IL-6 receptor in human disease
-
Kallen K.J. The role of transsignalling via the agonistic soluble IL-6 receptor in human disease. Biochem. Biophys. Acta 1592 (2002) 323-343
-
(2002)
Biochem. Biophys. Acta
, vol.1592
, pp. 323-343
-
-
Kallen, K.J.1
-
3
-
-
45849120200
-
Early effects of tocilizumab on bone and bone marrow lesions in a collagen-induced arthritis monkey model
-
Kato A., Matsuo S., Takaia H., Uchiyama Y., Mihara M., and Suzuki M. Early effects of tocilizumab on bone and bone marrow lesions in a collagen-induced arthritis monkey model. Exp. Mol. Pathol. 84 (2008) 262-270
-
(2008)
Exp. Mol. Pathol.
, vol.84
, pp. 262-270
-
-
Kato, A.1
Matsuo, S.2
Takaia, H.3
Uchiyama, Y.4
Mihara, M.5
Suzuki, M.6
-
4
-
-
0035090840
-
Humanized antibody to human interleukin-6 receptor inhibits the development of collagen arthritis in cynomolgus monkeys
-
Mihara M., Kotoh M., Nishimoto N., Oda Y., Kumagai E., Takagi N., Tsunemi K., Ohsugi Y., Kishimoto T., Yoshizaki K., and Takeda Y. Humanized antibody to human interleukin-6 receptor inhibits the development of collagen arthritis in cynomolgus monkeys. Clin. Immunol. 98 (2001) 319-326
-
(2001)
Clin. Immunol.
, vol.98
, pp. 319-326
-
-
Mihara, M.1
Kotoh, M.2
Nishimoto, N.3
Oda, Y.4
Kumagai, E.5
Takagi, N.6
Tsunemi, K.7
Ohsugi, Y.8
Kishimoto, T.9
Yoshizaki, K.10
Takeda, Y.11
-
5
-
-
20344381320
-
The therapy of autoimmune diseases by anti-interleukin-6 receptor antibody
-
Mihara M., Nishimoto N., and Ohsugi Y. The therapy of autoimmune diseases by anti-interleukin-6 receptor antibody. Expert Opin. Biol. Ther. 5 (2005) 683-690
-
(2005)
Expert Opin. Biol. Ther.
, vol.5
, pp. 683-690
-
-
Mihara, M.1
Nishimoto, N.2
Ohsugi, Y.3
-
6
-
-
23644442893
-
Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine family
-
Mihara M., Kasutani K., Okazaki M., Nakamura A., Kawai S., Sugimoto M., Matsumoto Y., and Ohsugi Y. Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine family. Int. Immunopharmacol. 5 (2005) 1731-1740
-
(2005)
Int. Immunopharmacol.
, vol.5
, pp. 1731-1740
-
-
Mihara, M.1
Kasutani, K.2
Okazaki, M.3
Nakamura, A.4
Kawai, S.5
Sugimoto, M.6
Matsumoto, Y.7
Ohsugi, Y.8
-
7
-
-
84925549112
-
The paradigm of IL-6: from basic science to medicine
-
Naka T., Nishimoto N., and Kishimoto T. The paradigm of IL-6: from basic science to medicine. Arthritis Res. 4 (2002) S233-S242
-
(2002)
Arthritis Res.
, vol.4
-
-
Naka, T.1
Nishimoto, N.2
Kishimoto, T.3
-
8
-
-
3342892420
-
Inhibition of IL-6 for the treatment of inflammatory diseases
-
Nishimoto N., and Kishimoto T. Inhibition of IL-6 for the treatment of inflammatory diseases. Curr. Opin. Pharmacol. 4 (2004) 386-391
-
(2004)
Curr. Opin. Pharmacol.
, vol.4
, pp. 386-391
-
-
Nishimoto, N.1
Kishimoto, T.2
-
9
-
-
36048991069
-
Recent advances in immunopathophysiology of interleukin-6: An innovative therapeutic drug, tocilzumab (recombinant humanized anti-human interleukin-6 receptor antibody), unveils the mysterious etiology of immune-mediated inflammatory diseases
-
Ohsugi Y. Recent advances in immunopathophysiology of interleukin-6: An innovative therapeutic drug, tocilzumab (recombinant humanized anti-human interleukin-6 receptor antibody), unveils the mysterious etiology of immune-mediated inflammatory diseases. Biol. Pharm. Bull. 30 (2007) 2001-2006
-
(2007)
Biol. Pharm. Bull.
, vol.30
, pp. 2001-2006
-
-
Ohsugi, Y.1
-
10
-
-
33750102235
-
Tocilizumab: blockade of interleukin-6 signaling pathway as a therapeutic strategy for inflammatory disorders
-
Paul-Pletzer K. Tocilizumab: blockade of interleukin-6 signaling pathway as a therapeutic strategy for inflammatory disorders. Drugs Today 42 (2006) 559-576
-
(2006)
Drugs Today
, vol.42
, pp. 559-576
-
-
Paul-Pletzer, K.1
-
11
-
-
0027502201
-
Reshaping a human antibody to inhibit the interleukin 6-dependent tumor cell growth
-
Sato K., Tsuchiya M., Saldanha J., Koishihara Y., Ohsugi Y., Kishimoto T., and Bendig M.M. Reshaping a human antibody to inhibit the interleukin 6-dependent tumor cell growth. Cancer Res. 53 (1993) 851-856
-
(1993)
Cancer Res.
, vol.53
, pp. 851-856
-
-
Sato, K.1
Tsuchiya, M.2
Saldanha, J.3
Koishihara, Y.4
Ohsugi, Y.5
Kishimoto, T.6
Bendig, M.M.7
-
12
-
-
0031812603
-
In vivo blocking effects of a humanized antibody to human interleukin-6 receptor on interleukin-6 functions in primates
-
Shinkura H., Imazeki I., Yamazaki M., Oda Y., Kotoh M., and Mihara M. In vivo blocking effects of a humanized antibody to human interleukin-6 receptor on interleukin-6 functions in primates. Anticancer Res. 18 (1998) 1217-1222
-
(1998)
Anticancer Res.
, vol.18
, pp. 1217-1222
-
-
Shinkura, H.1
Imazeki, I.2
Yamazaki, M.3
Oda, Y.4
Kotoh, M.5
Mihara, M.6
-
14
-
-
0023575852
-
Receptors for B cell stimulatory factor 2, quantitation, specificity, distribution, and regulation of their expression
-
Taga T., Kawanishi Y., Hardy R.R., Hirano T., and Kishimoto T. Receptors for B cell stimulatory factor 2, quantitation, specificity, distribution, and regulation of their expression. J. Exp. Med. 166 (1987) 967-981
-
(1987)
J. Exp. Med.
, vol.166
, pp. 967-981
-
-
Taga, T.1
Kawanishi, Y.2
Hardy, R.R.3
Hirano, T.4
Kishimoto, T.5
|