A recurrent truncating germline mutation in the BRIP1/FANCJ gene and susceptibility to prostate cancer

British Journal of Cancer

Volumn 100, Issue 2, 2009, Pages 426-430

  Kote Jarai, Z ^a   Jugurnauth, S ^a   Mulholland, S ^a   Leongamornlert, D A ^a   Guy, M ^a   Edwards, S ^a   Tymrakiewitcz, M ^a   O'Brien, L ^a   Hall, A ^a,b   Wilkinson, R ^a   Al Olama, A A ^c   Morrison, J ^c   Muir, K ^d   Neal, D ^e,f   Donovan, J ^g   Hamdy, F ^h   Easton, D F ^c   Eeles, R ^a,b  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^f IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^g UNIVERSITY OF BRISTOL   (United Kingdom)

^h UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Deleterious mutation; FANCJ BRIP1; Prostate cancer predisposition; SNPs

Indexed keywords

BRIP 1 PROTEIN; DNA; DOUBLE STRANDED DNA; FANCJ PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BR1P/FANCJ GENE; CANCER GENETICS; CANCER RISK; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; DNA STRAND BREAKAGE; FAMILIAL CANCER; GENE; GENE FUNCTION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC SCREENING; GENOME; GENOMICS; GERM LINE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MOLECULAR INTERACTION; POPULATION BASED CASE CONTROL STUDY; PRIORITY JOURNAL; PROSTATE CANCER; SINGLE NUCLEOTIDE POLYMORPHISM; UNITED KINGDOM;

AGE OF ONSET; AGED; CASE-CONTROL STUDIES; DNA; DNA-BINDING PROTEINS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GERM-LINE MUTATION; HUMANS; MALE; MIDDLE AGED; PEDIGREE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; PROSTATIC NEOPLASMS; RNA HELICASES;

EID: 58749096682     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6604847     Document Type: Article

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