Nitric oxide decreases expression of osmoprotective genes via direct inhibition of TonEBP transcriptional activity

Pflugers Archiv European Journal of Physiology

Volumn 457, Issue 4, 2009, Pages 831-843

  Neuhofer, Wolfgang ^a,b   Fraek, Maria Luisa ^a   Beck, Franz X ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

Nitric oxide; Osmosensitive genes; Protein nitrosylation; TonEBP

Indexed keywords

8 BROMO CYCLIC GMP; ALDEHYDE REDUCTASE; BINDING PROTEIN; BIOTIN; NITRIC OXIDE; NITRIC OXIDE DONOR; PEROXYNITRITE; TONICITY RESPONSIVE ENHANCER BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; DOG; DOWN REGULATION; GENE ACTIVITY; GENE CONSTRUCT; GENE EXPRESSION REGULATION; KIDNEY MEDULLA; NITROSYLATION; NONHUMAN; NUCLEAR IMPORT; OSMOTIC STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DNA BINDING; PROTEIN INTERACTION; PROTEIN TRANSPORT; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL LINE; CELL SURVIVAL; CYCLIC GMP; DOGS; GENE EXPRESSION REGULATION; GENES, REPORTER; NFATC TRANSCRIPTION FACTORS; NITRIC OXIDE; NITRIC OXIDE DONORS; PEROXYNITROUS ACID; TRANSCRIPTION, GENETIC; WATER-ELECTROLYTE BALANCE;

EID: 58649113614     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-008-0540-3     Document Type: Article

References (49)

1. KY Ahn MG Mohaupt KM Madsen BC Kone 1994 In situ hybridization localization of mRNA encoding inducible nitric oxide synthase in rat kidney Am J Physiol Renal Physiol 267 F748 F757
2. S Bachmann HM Bosse P Mundel 1995 Topography of nitric oxide synthesis by localizing constitutive NO synthases in mammalian kidney Am J Physiol 268 F885 898
3. K Bian K Davis J Kuret L Binder F Murad 1999 Nitrotyrosine formation with endotoxin-induced kidney injury detected by immunohistochemistry Am J Physiol 277 F33 40
4. DS Bredt 1999 Endogenous nitric oxide synthesis: biological functions and pathophysiology Free Radic Res 31 577 596
5. MA Carvalho-Filho M Ueno SM Hirabara AB Seabra JB Carvalheira MG de Oliveira LA Velloso R Curi MJ Saad 2005 S-nitrosation of the insulin receptor, insulin receptor substrate 1, and protein kinase B/Akt: a novel mechanism of insulin resistance Diabetes 54 959 967
6. S Chen L Cao HD Intengan M Humphreys DG Gardner 2002 Osmoregulation of endothelial nitric-oxide synthase gene expression in inner medullary collecting duct cells. Role in activation of the type A natriuretic peptide receptor J Biol Chem 277 32498 32504
7. DE Chou H Cai D Jayadevappa JG Porush 2002 Regional expression of inducible nitric oxide synthase in the kidney stimulated by lipopolysaccharide in the rat Exp Physiol 87 153 162
8. AW Cowley Jr. T Mori D Mattson AP Zou 2003 Role of renal NO production in the regulation of medullary blood flow Am J Physiol Regul Integr Comp Physiol 284 R1355 1369
9. A delaTorre RA Schroeder C Punzalan PC Kuo 1999 Endotoxin-mediated S-nitrosylation of p50 alters NF-kappa B-dependent gene transcription in ANA-1 murine macrophages J Immunol 162 4101 4108
10. DA Gomes WL Reis RR Ventura A Giusti-Paiva LL Elias FQ Cunha J Antunes-Rodrigues 2004 The role of carbon monoxide and nitric oxide in hyperosmolality-induced atrial natriuretic peptide release by hypothalamus in vitro Brain Res 1016 33 39
11. AJ Gow Q Chen DT Hess BJ Day H Ischiropoulos JS Stamler 2002 Basal and stimulated protein S-nitrosylation in multiple cell types and tissues J Biol Chem 277 9637 9640
12. U Hasler US Jeon JA Kim D Mordasini HM Kwon E Feraille PY Martin 2006 Tonicity-responsive enhancer binding protein is an essential regulator of aquaporin-2 expression in renal collecting duct principal cells J Am Soc Nephrol 17 1521 1531
13. DT Hess A Matsumoto SO Kim HE Marshall JS Stamler 2005 Protein S-nitrosylation: purview and parameters Nat Rev Mol Cell Biol 6 150 166
14. T Hla K Neilson 1992 Human cyclooxygenase-2 cDNA Proc Natl Acad Sci U S A 89 7384 7388
15. SR Jaffrey H Erdjument-Bromage CD Ferris P Tempst SH Snyder 2001 Protein S-nitrosylation: a physiological signal for neuronal nitric oxide Nat Cell Biol 3 193 197
16. US Jeon JA Kim MR Sheen HM Kwon 2006 How tonicity regulates genes: story of TonEBP transcriptional activator Acta Physiol (Oxf) 187 241 247
17. BC Ko B Ruepp KM Bohren KH Gabbay SS Chung 1997 Identification and characterization of multiple osmotic response sequences in the human aldose reductase gene J Biol Chem 272 16431 16437
18. HM Kwon A Yamauchi S Uchida AS Preston A Garcia-Perez MB Burg JS Handler 1992 Cloning of the cDNa for a Na+/myo-inositol cotransporter, a hypertonicity stress protein J Biol Chem 267 6297 6301
19. V Lahera MG Salom MJ Fiksen-Olsen L Raij JC Romero 1990 Effects of NG-monomethyl-l-arginine and l-arginine on acetylcholine renal response Hypertension 15 659 663
20. V Lahera MG Salom F Miranda-Guardiola S Moncada JC Romero 1991 Effects of NG-nitro-l-arginine methyl ester on renal function and blood pressure Am J Physiol 261 F1033 1037
21. AK Lam BC Ko S Tam R Morris JY Yang SK Chung SS Chung 2004 Osmotic response element-binding protein (OREBP) is an essential regulator of the urine concentrating mechanism J Biol Chem 279 48048 48054
22. SD Lee SK Woo HM Kwon 2002 Dimerization is required for phosphorylation and DNA binding of TonEBP/NFAT5 Biochem Biophys Res Commun 294 968 975
23. DS Majid SA Omoro SY Chin LG Navar 1998 Intrarenal nitric oxide activity and pressure natriuresis in anesthetized dogs Hypertension 32 266 272
24. JR Matthews CH Botting M Panico HR Morris RT Hay 1996 Inhibition of NF-kappaB DNA binding by nitric oxide Nucleic Acids Res 24 2236 2242
25. DL Mattson F Wu 2000 Control of arterial blood pressure and renal sodium excretion by nitric oxide synthase in the renal medulla Acta Physiol Scand 168 149 154
26. H Miyakawa SK Woo CP Chen SC Dahl JS Handler HM Kwon 1998 Cis- and trans-acting factors regulating transcription of the BGT1 gene in response to hypertonicity Am J Physiol 274 F753 761
27. H Miyakawa SK Woo SC Dahl JS Handler HM Kwon 1999 Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity Proc Natl Acad Sci U S A 96 2538 2542
28. MG Mohaupt JL Elzie KY Ahn WL Clapp CS Wilcox BC Kone 1994 Differential expression and induction of mRNAs encoding two inducible nitric oxide synthases in rat kidney Kidney Int 46 653 665
29. T Mori AW Cowley Jr. 2004 Renal oxidative stress in medullary thick ascending limbs produced by elevated NaCl and glucose Hypertension 43 341 346
30. Y Nakayama T Peng JM Sands SM Bagnasco 2000 The TonE/TonEBP pathway mediates tonicity-responsive regulation of UT-A urea transporter expression J Biol Chem 275 38275 38280
31. K Nash A Hafeez S Hou 2002 Hospital-acquired renal insufficiency Am J Kidney Dis 39 930 936
32. W Neuhofer H Bartels ML Fraek FX Beck 2002 Relationship between intracellular ionic strength and expression of tonicity-responsive genes in rat papillary collecting duct cells J Physiol 543 147 153
33. W Neuhofer FX Beck 2005 Cell survival in the hostile environment of the renal medulla Annu Rev Physiol 67 531 555
34. W Neuhofer D Steinert ML Fraek FX Beck 2007 Prostaglandin E2 stimulates expression of osmoprotective genes in MDCK cells and promotes survival under hypertonic conditions J Physiol 583 287 297
35. C Nishimura Y Matsuura Y Kokai T Akera D Carper N Morjana C Lyons TG Flynn 1990 Cloning and expression of human aldose reductase J Biol Chem 265 9788 9792
36. PA Ortiz JL Garvin 2002 Role of nitric oxide in the regulation of nephron transport Am J Physiol Renal Physiol 282 F777 F784
37. PA Ortiz NJ Hong JL Garvin 2001 NO decreases thick ascending limb chloride absorption by reducing Na(+)-K(+)-2Cl(-) cotransporter activity Am J Physiol Renal Physiol 281 F819 F825
38. SK Park HL Lin S Murphy 1997 Nitric oxide regulates nitric oxide synthase-2 gene expression by inhibiting NF-kappaB binding to DNA Biochem J 322 Pt 2 609 613
39. HH Schmidt TD Warner M Nakane U Forstermann F Murad 1992 Regulation and subcellular location of nitrogen oxide synthases in RAW264.7 macrophages Mol Pharmacol 41 615 624
40. JS Stamler S Lamas FC Fang 2001 Nitrosylation. The prototypic redox-based signaling mechanism Cell 106 675 683
41. BA Stoos NH Garcia JL Garvin 1995 Nitric oxide inhibits sodium reabsorption in the isolated perfused cortical collecting duct J Am Soc Nephrol 6 89 94
42. JC Stroud C Lopez-Rodriguez A Rao L Chen 2002 Structure of a TonEBP-DNA complex reveals DNA encircled by a transcription factor Nat Struct Biol 9 90 94
43. M Takenaka AS Preston HM Kwon JS Handler 1994 The tonicity-sensitive element that mediates increased transcription of the betaine transporter gene in response to hypertonic stress J Biol Chem 269 29379 29381
44. Y Terada K Tomita H Nonoguchi F Marumo 1992 Polymerase chain reaction localization of constitutive nitric oxide synthase and soluble guanylate cyclase messenger RNAs in microdissected rat nephron segments J Clin Invest 90 659 665
45. SK Woo SC Dahl JS Handler HM Kwon 2000 Bidirectional regulation of tonicity-responsive enhancer binding protein in response to changes in tonicity Am J Physiol Renal Physiol 278 F1006 1012
46. SK Woo SD Lee HM Kwon 2002 TonEBP transcriptional activator in the cellular response to increased osmolality Pflügers Arch 444 579 585
47. F Wu F Park AW Cowley Jr. DL Mattson 1999 Quantification of nitric oxide synthase activity in microdissected segments of the rat kidney Am J Physiol 276 F874 881
48. T Yang A Zhang A Pasumarthy L Zhang Z Warnock JB Schnermann 2006 Nitric oxide stimulates COX-2 expression in cultured collecting duct cells through MAP kinases and superoxide but not cGMP Am J Physiol Renal Physiol 291 F891 895
49. X Zhou JD Ferraris MB Burg 2005 Mitochondrial reactive oxygen species contribute to high NaCl-induced activation of the transcription factor TonEBP/OREBP Am J Physiol Renal Physiol 290 F1169 F1176