Antibiotics LL-Z1272 identified as novel inhibitors discriminating bacterial and mitochondrial quinol oxidases

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1787, Issue 2, 2009, Pages 129-133

  Mogi, Tatsushi ^a   Ui, Hideaki ^b   Shiomi, Kazuro ^b   Omura, Satoshi ^b   Miyoshi, Hideto ^c   Kita, Kiyoshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b KITASATO UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Alternative oxidase; Escherichia coli; Inhibitor; Natural antibiotic; Quinol oxidase; Trypanosoma brucei

Indexed keywords

ANTIBIOTIC AGENT; LL Z1272 BETA; LL Z1272 DELTA; LL Z1272 EPSILON; LL Z1272 GAMMA; LL Z1272 ZETA; OXIDOREDUCTASE; PHENOL DERIVATIVE; QUINOL OXIDASE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; DRUG MECHANISM; DRUG STRUCTURE; ENZYME INHIBITION; ESCHERICHIA COLI; IC 50; OXIDATION; PRIORITY JOURNAL;

ANIMALS; ANTI-BACTERIAL AGENTS; BENZALDEHYDES; CELL MEMBRANE; CYTOCHROME B GROUP; CYTOCHROMES; CYTOPLASMIC VESICLES; ELECTRON TRANSPORT CHAIN COMPLEX PROTEINS; ENZYME INHIBITORS; ESCHERICHIA COLI PROTEINS; MITOCHONDRIA; OXIDOREDUCTASES; TRYPANOSOMA BRUCEI BRUCEI; VERTICILLIUM;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MAMMALIA; TRYPANOSOMA BRUCEI;

EID: 58649098300     PISSN: 00052728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbabio.2008.11.016     Document Type: Article

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