Exocytosis of insulin: In vivo maturation of mouse endocrine pancreas

Annals of the New York Academy of Sciences

Volumn 1152, Issue , 2009, Pages 53-62

  Rozzo, Aldo ^a,b   Meneghel Rozzo, Tiziana ^a   Delakorda, Saša Lipovšek ^c   Yang, Shi Bing ^a,d   Rupnik, Marjan ^a,c  

^a EUROPEAN NEUROSCIENCE INSTITUTE   (Germany)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF MARIBOR   (Slovenia)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Beta cell maturation; Developing pancreas; Embryo; Insulin release; Newborn

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CALCIUM CHANNEL; GLUCOSE; INSULIN; ION CHANNEL; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL TISSUE; CONFERENCE PAPER; ELECTRIC ACTIVITY; EMBRYO; EMBRYO DEVELOPMENT; ENDOCRINE PANCREAS MATURATION; EXOCYTOSIS; IN VIVO STUDY; INSULIN RELEASE; MOUSE; NONHUMAN; ORGANOGENESIS; PANCREAS ISLET BETA CELL; POSTNATAL DEVELOPMENT;

EID: 58549087956     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2008.04003.x     Document Type: Conference Paper

References (25)

1. Edlund, H. 2002. Pancreatic organogenesis-developmental mechanisms and implications for therapy. Nat. Rev. Genet. 3 : 524 32.
2. Lammert, E., O. Cleaver & D. Melton. 2003. Role of endothelial cells in early pancreas and liver development. Mech. Dev. 120 : 59 64.
3. Habener, J.F., D.M. Kemp & M.K. Thomas. 2005. Minireview: transcriptional regulation in pancreatic development. Endocrinology 146 : 1025 1034.
4. Bonner-Weir, S. et al. 2004. The pancreatic ductal epithelium serves as a potential pool of progenitor cells. Pediatr. Diabetes 5 (Suppl 2 16 22.
5. Murtaugh, L.C. & D.A. Melton. 2003. Genes, signals, and lineages in pancreas development. Annu. Rev. Cell Dev. Biol. 19 : 71 89.
6. Georgia, S. & A. Bhushan. 2004. Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass. J. Clin. Invest. 114 : 963 968.
7. Alvarez, C. et al. 1997. Contrasted impact of maternal rat food restriction on the fetal endocrine pancreas. Endocrinology 138 : 2267 2273.
8. Taniguchi, S., K. Tanigawa & I. Miwa. 2000. Immaturity of glucose-induced insulin secretion in fetal rat islets is due to low glucokinase activity. Horm. Metab. Res. 32 : 97 102.
9. Meneghel-Rozzo, T. et al. 2004. In vivo and in vitro development of mouse pancreatic beta-cells in organotypic slices. Cell Tissue Res. 316 : 295 303.
10. Montanya, E. et al. 2000. Linear correlation between beta-cell mass and body weight throughout the lifespan in Lewis rats: role of beta-cell hyperplasia and hypertrophy. Diabetes 49 : 1341 1346.
11. Detimary, P., J.C. Jonas & J.C. Henquin. 1995. Possible links between glucose-induced changes in the energy state of pancreatic B cells and insulin release. Unmasking by decreasing a stable pool of adenine nucleotides in mouse islets. J. Clin. Invest. 96 : 1738 1745.
12. Gopel, S. et al. 1999. Voltage-gated and resting membrane currents recorded from B-cells in intact mouse pancreatic islets. J. Physiol. 521 (Pt 3 717 728.
13. Pang, K., C. Mukonoweshuro & G.G. Wong. 1994. Beta cells arise from glucose transporter type 2 (Glut2)-expressing epithelial cells of the developing rat pancreas. Proc. Natl. Acad. Sci. USA 91 : 9559 9563.
14. Bonner-Weir, S. & A. Sharma. 2002. Pancreatic stem cells. J. Pathol. 197 : 519 526.
15. Henquin, J.C. et al. 1975. Quinine-induced modifications of insulin release and glucose metabolism by isolated pancreatic islets. FEBS Lett. 57 : 280 284.
16. Atwater, I. et al. 1984. Cooling dissociates glucose-induced insulin release from electrical activity and cation fluxes in rodent pancreatic islets. J. Physiol. 348 : 615 627.
17. Dean, P.M. & E.K. Matthews. 1970. Glucose-induced electrical activity in pancreatic islet cells. J. Physiol. 210 : 255 264.
18. Sussel, L. et al. 1998. Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells. Development 125 : 2213 2221.
19. Naya, F.J. et al. 1997. Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice. Genes Dev. 11 : 2323 2334.
20. Sosa-Pineda, B. et al. 1997. The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas. Nature 386 : 399 402.
21. Collombat, P. et al. 2005. The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the [alpha]- and [beta]-cell lineages in the mouse endocrine pancreas. Development 132 : 2969 2980.
22. Nakamura, T. et al. 2004. Genome-wide cDNA microarray analysis of gene expression profiles in pancreatic cancers using populations of tumor cells and normal ductal epithelial cells selected for purity by laser microdissection. Oncogene 23 : 2385 2400.
23. Smith, P.A., F.M. Ashcroft & P. Rorsman. 1990. Simultaneous recordings of glucose dependent electrical activity and ATP-regulated K(+)-currents in isolated mouse pancreatic beta-cells. FEBS Lett. 261 : 187 190.
24. Speier, S. et al. 2005. KATP-channels in beta-cells in tissue slices are directly modulated by millimolar ATP. Mol Cell Endocrinol. 230 : 51 58.
25. Blyszczuk, P. et al. 2004. Embryonic stem cells differentiate into insulin-producing cells without selection of nestin-expressing cells. Int. J. Dev. Biol. 48 : 1095 1104.