cAMP-dependent and cholinergic regulation of the electrogenic intestinal/ pancreatic Na+/HCO3-cotransporter pNBC1 in human embryonic kidney (HEK293) cells

BMC Cell Biology

Volumn 9, Issue , 2008, Pages

  Bachmann, Oliver ^a   Franke, Kristin ^a,c   Yu, Haoyang ^a   Riederer, Brigitte ^a   Li, Hong C ^b   Soleimani, Manoocher ^a   Manns, Michael P ^a   Seidler, Ursula ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BICARBONATE; BICARBONATE SODIUM COTRANSPORTER; CARBACHOL; CARBON DIOXIDE; CYCLIC AMP; FORSKOLIN; GREEN FLUORESCENT PROTEIN; CHOLINERGIC RECEPTOR STIMULATING AGENT; SLC4A4 PROTEIN, HUMAN; SODIUM;

ARTICLE; CELL STRAIN HEK293; CELL TYPE; CHOLINERGIC ACTIVITY; CHOLINERGIC STIMULATION; COLON; CONFOCAL MICROSCOPY; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INCUBATION TIME; INTESTINE; ION TRANSPORT; NUCLEOTIDE SEQUENCE; PH; CELL LINE; GENETICS; METABOLISM;

MURINAE;

BICARBONATES; CARBACHOL; CELL LINE; CHOLINERGIC AGONISTS; CYCLIC AMP; HUMANS; INTESTINES; ION TRANSPORT; SODIUM; SODIUM-BICARBONATE SYMPORTERS;

EID: 58549083986     PISSN: None     EISSN: 14712121     Source Type: Journal    
DOI: 10.1186/1471-2121-9-70     Document Type: Article

References (38)

1. Ruiz OS Arruda JA Regulation of the renal Na-HCO3 cotransporter by cAMP and Ca-dependent protein kinases Am J Physiol 1992, 262:F560-F565. 1314505
2. Jacob P Christiani S Rossmann H Lamprecht G Vieillard-Baron D Muller R et al.: Role of Na(+)HCO(3)(-) cotransporter NBC1, Na(+)/H(+) exchanger NHE1, and carbonic anhydrase in rabbit duodenal bicarbonate secretion Gastroenterology 2000, 119:406-419. 10.1053/gast.2000.9358 10930376
3. Yun CH Oh S Zizak M Steplock D Tsao S Tse CM et al.: CAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory protein Proc Natl Acad Sci USA 1997, 94:3010-3015. 20313 9096337 10.1073/pnas.94.7.3010
4. Bachmann O Rossmann H Berger UV Colledge WH Ratcliff R Evans MJ et al.: cAMP-mediated regulation of murine intestinal/pancreatic Na+/ HCO3-cotransporter subtype pNBC1 Am J Physiol Gastrointest Liver Physiol 2003, 284:G37-G45. 12388213
5. Ruiz OS Qiu YY Cardoso LR Arruda JA et al.: Regulation of the renal Na-HCO3 cotransporter: VII. Mechanism of the cholinergic stimulation Kidney Int 1997, 51:1069-1077. 10.1038/ki.1997.149 9083272
6. Bachmann O Reichelt D Tuo B Manns MP Seidler U Carbachol increases Na+ -HCO3-cotransport activity in murine colonic crypts in a M3-, Ca2+/ calmodulin-, and PKC-dependent manner Am J Physiol Gastrointest Liver Physiol 2006, 291:G650-G657. 10.1152/ajpgi.00376.2005 16675744
7. Gross E Fedotoff O Pushkin A Abuladze N Newman D Kurtz I Phosphorylation-induced modulation of pNBC1 function: Distinct roles for the amino- and carboxy-termini J Physiol 2003, 549:673-682. 2342979 12730338 10.1113/jphysiol.2003.042226
8. Gross E Kurtz I Structural determinants and significance of regulation of electrogenic Na(+)-HCO(3)(-) cotransporter stoichiometry Am J Physiol Renal Physiol 2002, 283:F876-F887. 12372762
9. Abuladze N Lee I Newman D Hwang J Boorer K Pushkin A et al.: Molecular cloning, chromosomal localization, tissue distribution, and functional expression of the human pancreatic sodium bicarbonate cotransporter J Biol Chem 1998, 273:17689-17695. 10.1074/jbc.273.28.17689 9651366
10. Murtazina R Kovbasnjuk O Zachos NC Li X Chen Y Hubbard A et al.: Tissue specific regulation of sodium-proton exchanger isoform 3 (NHE3) activity in NA/H exchanger regulatory factor 1 (NHERF1) null mice: CAMP inhibition is differentially dependent on NHERF1 and exchange protein directly activated by cAMP(EPAC) in ileum versus proximal tubule J Biol Chem 2007. 17580307
11. Moe OW Miller RT Horie S Cano A Preisig PA Alpern RJ Differential regulation of Na/H antiporter by acid in renal epithelial cells and fibroblasts J Clin Invest 1991, 88:1703-1708. 295708 1658050 10.1172/ JCI115487
12. Rossmann H Bachmann O Wang Z Shull GE Obermaier B Stuart-Tilley A et al.: Differential expression and regulation of AE2 anion exchanger subtypes in rabbit parietal and mucous cells J Physiol 2001, 534:837-848. 2278731 11483713 10.1111/j.1469-7793.2001.00837.x
13. Kulka M Dery R Nahirney D Duszyk M Befus AD Differential regulation of cystic fibrosis transmembrane conductance regulator by interferon gamma in mast cells and epithelial cells J Pharmacol Exp Ther 2005, 315:563-570. 10.1124/jpet.105.087528 16051699
14. Cinar A Chen M Riederer B Bachmann O Wiemann M Manns M et al.: NHE3 inhibition by cAMP and Ca2+ is abolished in PDZ-domain protein PDZK1-deficient murine enterocytes J Physiol 2007, 581:1235-1246. 2170846 17395628 10.1113/jphysiol.2007.131722
15. Lang K Wagner C Haddad G Burnekova O Geibel J Intracellular pH activates membrane-bound Na(+)/H(+) exchanger and vacuolar H(+)-ATPase in human embryonic kidney (HEK) cells Cell Physiol Biochem 2003, 13:257-262. 10.1159/000074540 14586169
16. Willoughby D Masada N Crossthwaite AJ Ciruela A Cooper DM Localized Na+/ H+ exchanger 1 expression protects Ca2+-regulated adenylyl cyclases from changes in intracellular pH J Biol Chem 2005, 280:30864-30872. 10.1074/ jbc.M414355200 16002403
17. Luo J Busillo JM Benovic JL M3 Muscarinic Acetylcholine Receptor-Mediated Signaling is Regulated by Distinct Mechanisms Mol Pharmacol 2008, 74(2):338-347. 10.1124/mol.107.044750 18388243
18. Gross E Abuladze N Pushkin A Kurtz I Cotton CU The stoichiometry of the electrogenic sodium bicarbonate cotransporter pNBC1 in mouse pancreatic duct cells is 2 HCO(3)(-):1 Na(+) J Physiol 2001, 531:375-382. 2278477 11230510 10.1111/j.1469-7793.2001.0375i.x
19. Bok D Schibler MJ Pushkin A Sassani P Abuladze N Naser Z Immunolocalization of electrogenic sodium-bicarbonate cotransporters pNBC1 and kNBC1 in the rat eye Am J Physiol Renal Physiol 2001, 281:F920-F935. 11592950
20. Moser AJ Gangopadhyay A Bradbury NA Peters KW Frizzell RA Bridges RJ Electrogenic bicarbonate secretion by prairie dog gallbladder Am J Physiol Gastrointest Liver Physiol 2007, 292:G1683-G1694. 10.1152/ ajpgi.00268.2006 17363467
21. Kim YB Yang BH Piao ZG Oh SB Kim JS Park K Expression of Na+/ HCO3-cotransporter and its role in pH regulation in mouse parotid acinar cells Biochem Biophys Res Commun 2003, 304:593-598. 10.1016/ S0006-291X(03)00632-6 12727194
22. Pedrosa R Goncalves N Hopfer U Jose PA Soares-da-Silva P Activity and Regulation of Na+-HCO3-Cotransporter in Immortalized Spontaneously Hypertensive Rat and Wistar-Kyoto Rat Proximal Tubular Epithelial Cells Hypertension 2007, 49:1186-1193. 10.1161/HYPERTENSIONAHA.106.083444 17325238
23. Brandes A Oehlke O Schumann A Heidrich S Thevenod F Roussa E Adaptive redistribution of NBCe1-A and NBCe1-B in rat kidney proximal tubule and striated ducts of salivary glands during acid-base disturbances Am J Physiol Regul Integr Comp Physiol 2007, 293:R2400-R2411. 17855492
24. Khandoudi N Albadine J Robert P Krief S Berrebi-Bertrand I Martin X et al.: Inhibition of the cardiac electrogenic sodium bicarbonate cotransporter reduces ischemic injury Cardiovasc Res 2001, 52:387-396. 10.1016/S0008-6363(01)00430-8 11738055
25. Schmitt BM Biemesderfer D Romero MF Boulpaep EL Boron WF Immunolocalization of the electrogenic Na+-HCO-3 cotransporter in mammalian and amphibian kidney Am J Physiol 1999, 276:F27-F38. 9887077
26. Amlal H Wang Z Burnham C Soleimani M Functional characterization of a cloned human kidney Na+:HCO3-cotransporter J Biol Chem 1998, 273:16810-16815. 10.1074/jbc.273.27.16810 9642239
27. Osypiw JC Gleeson D Lobley RW Pemberton PW McMahon RF Acid-base transport systems in a polarized human intestinal cell monolayer: Caco-2 Exp Physiol 1994, 79:723-739. 7818862
28. Ramirez MA Toriano R Parisi M Malnic G Control of cell pH in the T84 colon cell line J Membr Biol 2000, 177:149-157. 10.1007/s002320001108 11003689
29. Zhu JX Yang N He Q Tsang LL Zhao WC Chung YW Differential Cl- and HCO3-mediated anion secretion by different colonic cell types in response to tetromethylpyrazine World J Gastroenterol 2004, 10:1763-1768. 15188502
30. Bernardo AA Kear FT Santos AV Ma J Steplock D Robey RB et al.: Basolateral Na(+)/HCO(3)(-) cotransport activity is regulated by the dissociable Na(+)/H(+) exchanger regulatory factor J Clin Invest 1999, 104:195-201. 408472 10411549 10.1172/JCI5344
31. Weinman EJ Evangelista CM Steplock D Liu MZ Shenolikar S Bernardo A Essential role for NHERF in cAMP-mediated inhibition of the Na+ -HCO3-co-transporter in BSC-1 cells J Biol Chem 2001, 276:42339-42346. 10.1074/jbc.M106153200 11535598
32. Shirakabe K Priori G Yamada H Ando H Horita S Fujita T et al.: IRBIT, an inositol 1,4,5-trisphosphate receptor-binding protein, specifically binds to and activates pancreas-type Na+/ Proc Natl Acad Sci USA 2006, 103:9542-9547. 1480443 16769890 10.1073/pnas.0602250103
33. Ando H Mizutani A Matsu-ura T Mikoshiba K IRBIT, a novel inositol 1,4,5-trisphosphate (IP3) receptor-binding protein, is released from the IP3 receptor upon IP3 binding to the receptor J Biol Chem 2003, 278:10602-10612. 10.1074/jbc.M210119200 12525476
34. Purkerson JM Schwartz GJ Expression of membrane-associated carbonic anhydrase isoforms IV, IX, XII, and XIV in the rabbit: Induction of CA IV and IX during maturation Am J Physiol Regul Integr Comp Physiol 2005, 288:R1256-R1263. 15821283
35. Alvarez BV Loiselle FB Supuran CT Schwartz GJ Casey JR Direct extracellular interaction between carbonic anhydrase IV and the human NBC1 sodium/bicarbonate co-transporter Biochemistry 2003, 42:12321-12329. 10.1021/bi0353124 14567693
36. Becker HM Deitmer JW Carbonic anhydrase II increases the activity of the human electrogenic Na+/HCO3-cotransporter J Biol Chem 2007, 282:13508-13521. 10.1074/jbc.M700066200 17353189
37. Piermarini PM Kim EY Boron WF Evidence against a direct interaction between intracellular carbonic anhydrase II and pure C-terminal domains of SLC4 bicarbonate transporters J Biol Chem 2007, 282:1409-1421. 10.1074/jbc.M608261200 17090540
38. Jordan M Schallhorn A Wurm FM Transfecting mammalian cells: Optimization of critical parameters affecting calcium-phosphate precipitate formation Nucleic Acids Res 1996, 24:596-601. 145683 8604299 10.1093/nar/24.4.596.