Pitfalls in the design and analysis of paediatric clinical trials: A case of a 'failed' multi-centre study, and potential solutions

Acta Paediatrica, International Journal of Paediatrics

Volumn 98, Issue 2, 2009, Pages 385-391

  Van Der Lee, Johanna H ^a,c   Tanck, Michael W T ^a   Wesseling, Judit ^a,b   Offringa, Martin ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b RED CROSS HOSPITAL   (Netherlands)

^c EMMA CHILDREN S HOSPITAL   (Netherlands)

Author keywords

Clinical trials; Paediatrics; Sample size; Statistics

Indexed keywords

DEXAMETHASONE; PLACEBO;

ARTERIAL GAS; ARTICLE; ARTIFICIAL VENTILATION; BRONCHIOLITIS; CLINICAL RESEARCH; CLINICAL TRIAL; DECISION MAKING; DRUG EFFICACY; HUMAN; INTENSIVE CARE UNIT; PNEUMONIA; PRIORITY JOURNAL; QUALITY CONTROL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; TREATMENT DURATION;

CHILD, PRESCHOOL; CLINICAL TRIALS AS TOPIC; DEXAMETHASONE; HUMANS; MULTICENTER STUDIES AS TOPIC; RESPIRATION, ARTIFICIAL; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; SAMPLE SIZE; TIME FACTORS;

EID: 58449135786     PISSN: 08035253     EISSN: 16512227     Source Type: Journal    
DOI: 10.1111/j.1651-2227.2008.01048.x     Document Type: Article

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