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Volumn 364, Issue 9436, 2004, Pages 803-811

Clinical trials in children

Author keywords

[No Author keywords available]

Indexed keywords

CHILD; CLINICAL PRACTICE; CLINICAL RESEARCH; CLINICAL TRIAL; DECISION MAKING; FINANCIAL MANAGEMENT; FUTUROLOGY; HUMAN; INFORMATION PROCESSING; INFORMED CONSENT; MARKET; MEDICAL RESEARCH; METHODOLOGY; ONCOLOGY; PARENT; PHYSICIAN; POLICY; PRIORITY JOURNAL; RESEARCH ETHICS; REVIEW;

EID: 4444351808     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(04)16942-0     Document Type: Review
Times cited : (384)

References (113)
  • 1
    • 0027103631 scopus 로고
    • Treatment of childhood acute lymphoblastic leukemia: Present issues and future prospects
    • Chessells JM. Treatment of childhood acute lymphoblastic leukemia: present issues and future prospects. Blood Rev. 6:1992;193-203
    • (1992) Blood Rev , vol.6 , pp. 193-203
    • Chessells, J.M.1
  • 2
    • 0032887329 scopus 로고    scopus 로고
    • An update on the therapeutic orphan
    • Wilson JT. An update on the therapeutic orphan. Pediatrics. 104:1999;585-590
    • (1999) Pediatrics , vol.104 , pp. 585-590
    • Wilson, J.T.1
  • 3
    • 0042195862 scopus 로고    scopus 로고
    • Pediatric drug labeling. Improving the safety and efficacy of pediatric therapies
    • Roberts R, Rodriguez W, Murphy D, Crescenzi T. Pediatric drug labeling. Improving the safety and efficacy of pediatric therapies. JAMA. 290:2003;905-911
    • (2003) JAMA , vol.290 , pp. 905-911
    • Roberts, R.1    Rodriguez, W.2    Murphy, D.3    Crescenzi, T.4
  • 4
    • 0000022275 scopus 로고
    • A difference in mortality rate and incidence of kernicterus among premature infants allotted to two prophylactic antibacterial regimes
    • Silverman WA, Andersen DH, Blanc WA, Crozier DN. A difference in mortality rate and incidence of kernicterus among premature infants allotted to two prophylactic antibacterial regimes. Pediatrics. 18:1956;614-625
    • (1956) Pediatrics , vol.18 , pp. 614-625
    • Silverman, W.A.1    Andersen, D.H.2    Blanc, W.A.3    Crozier, D.N.4
  • 5
    • 0032844199 scopus 로고    scopus 로고
    • Research in children: Ethical and scientific aspects
    • Smyth RL, Weindling AM. Research in children: ethical and scientific aspects. Lancet 1999; 354 (suppl II): 2124.
    • (1999) Lancet , vol.354 , Issue.2 SUPPL. , pp. 2124
    • Smyth, R.L.1    Weindling, A.M.2
  • 6
    • 0037206361 scopus 로고    scopus 로고
    • Testing medications in children
    • Steinbrook R. Testing medications in children. N Engl J Med. 347:2002;1462-1470
    • (2002) N Engl J Med , vol.347 , pp. 1462-1470
    • Steinbrook, R.1
  • 8
    • 0026500461 scopus 로고
    • Redressing the balance: The ethics of not entering an eligible patient on a randomised clinical trial
    • Segelov E, Tattersall MHN, Coates AS. Redressing the balance: the ethics of not entering an eligible patient on a randomised clinical trial. Ann Oncol. 3:1992;103-105
    • (1992) Ann Oncol , vol.3 , pp. 103-105
    • Segelov, E.1    Tattersall, M.H.N.2    Coates, A.S.3
  • 10
    • 0028070548 scopus 로고
    • The continuing unethical use of placebo controls
    • Rothman KJ, Michels KB. The continuing unethical use of placebo controls. N Engl J Med. 331:1994;394-398
    • (1994) N Engl J Med , vol.331 , pp. 394-398
    • Rothman, K.J.1    Michels, K.B.2
  • 11
    • 0032826396 scopus 로고    scopus 로고
    • Doctors' participation in randomized trials of adjuvant systemic therapy in breast cancer: How does it relate to their recommendations for standard therapy in breast cancer?
    • Ellis PM, Butow PN, Simes RJ, Tattersall MHN, Dunn SM, MacLeod C. Doctors' participation in randomized trials of adjuvant systemic therapy in breast cancer: how does it relate to their recommendations for standard therapy in breast cancer? Breast. 8:1999;182-187
    • (1999) Breast , vol.8 , pp. 182-187
    • Ellis, P.M.1    Butow, P.N.2    Simes, R.J.3    Tattersall, M.H.N.4    Dunn, S.M.5    MacLeod, C.6
  • 12
    • 84975693646 scopus 로고    scopus 로고
    • Outcomes of patients who participate in randomised controlled trials versus those of similar patients who do not participate (protocol for a Cochrane methodology review)
    • Vist GE, Hagen KB, Devereaux PJ, Oxman AD. Outcomes of patients who participate in randomised controlled trials versus those of similar patients who do not participate (protocol for a Cochrane methodology review). In: The Cochrane Library, Issue 4, 2001.
    • (2001) The Cochrane Library , Issue.4
    • Vist, G.E.1    Hagen, K.B.2    Devereaux, P.J.3    Oxman, A.D.4
  • 13
    • 0033036772 scopus 로고    scopus 로고
    • Do sick newborn infants benefit from participation in a randomized clinical trial?
    • Schmidt B, Gillie P, Caco C, Roberts J, Roberts R. Do sick newborn infants benefit from participation in a randomized clinical trial? J Pediatr. 134:1999;151-155
    • (1999) J Pediatr , vol.134 , pp. 151-155
    • Schmidt, B.1    Gillie, P.2    Caco, C.3    Roberts, J.4    Roberts, R.5
  • 14
    • 0021929933 scopus 로고
    • Participants in prospective, randomized clinical trials for resected non-small cell lung cancer have improved survival compared with nonparticipants in such trials
    • Davis S, Wright PW, Schulman SF, et al. Participants in prospective, randomized clinical trials for resected non-small cell lung cancer have improved survival compared with nonparticipants in such trials. Cancer. 56:1985;1710-1718
    • (1985) Cancer , vol.56 , pp. 1710-1718
    • Davis, S.1    Wright, P.W.2    Schulman, S.F.3
  • 16
    • 0032561868 scopus 로고    scopus 로고
    • Understanding controlled trials: What are pragmatic trials?
    • Roland M, Torgerson DJ. Understanding controlled trials: what are pragmatic trials? BMJ. 316:1998;285
    • (1998) BMJ , vol.316 , pp. 285
    • Roland, M.1    Torgerson, D.J.2
  • 17
    • 0037328996 scopus 로고    scopus 로고
    • When do the federal regulations allow placebo-controlled trials in children
    • Miller FG, Wendler D, Wilfond B. When do the federal regulations allow placebo-controlled trials in children. J Pediatr. 142:2003;102-107
    • (2003) J Pediatr , vol.142 , pp. 102-107
    • Miller, F.G.1    Wendler, D.2    Wilfond, B.3
  • 18
    • 0037329681 scopus 로고    scopus 로고
    • Do healthy children deserve greater protection in medical research?
    • Ross LF. Do healthy children deserve greater protection in medical research? J Pediatr. 142:2003;108-112
    • (2003) J Pediatr , vol.142 , pp. 108-112
    • Ross, L.F.1
  • 20
    • 0012111908 scopus 로고    scopus 로고
    • Health research with children: The New Zealand experience
    • Peart N. Health research with children: the New Zealand experience. Curr Legal Issues. 3:2000;421-439
    • (2000) Curr Legal Issues , vol.3 , pp. 421-439
    • Peart, N.1
  • 21
    • 0034021319 scopus 로고    scopus 로고
    • Royal College of Paediatrics and Child Health: Ethics advisory committee - Guidelines for the ethical conduct of medical research involving children
    • Royal College of Paediatrics and Child Health: ethics advisory committee - guidelines for the ethical conduct of medical research involving children. Arch Dis Child 2000; 82: 177-82.
    • (2000) Arch Dis Child , vol.82 , pp. 177-182
  • 22
    • 4444234166 scopus 로고    scopus 로고
    • Parents' attitudes to randomised controlled trials involving children
    • Caldwell PHY, Butow PN, Craig JC. Parents' attitudes to randomised controlled trials involving children. J Pediatr. 145:2003;555-560
    • (2003) J Pediatr , vol.145 , pp. 555-560
    • Caldwell, P.H.Y.1    Butow, P.N.2    Craig, J.C.3
  • 24
    • 0033837949 scopus 로고    scopus 로고
    • Pediatric drug development: The international conference on harmonization focus on clinical investigations in children
    • Simar MR. Pediatric drug development: the international conference on harmonization focus on clinical investigations in children. Drug Info J. 34:2000;809-819
    • (2000) Drug Info J , vol.34 , pp. 809-819
    • Simar, M.R.1
  • 27
    • 4444351915 scopus 로고    scopus 로고
    • Europa. Ethical Rules for FP6. http://europa.eu.int/comm/research/ science-society/ethics/rules_en.html (accessed Mar 30, 2004).
    • Ethical Rules for FP6
  • 29
    • 4444376284 scopus 로고    scopus 로고
    • National Health and Medical Research Council. http://www.health.gov.au/ nhmrc/ (accessed April, 2004)
  • 31
    • 4444345571 scopus 로고    scopus 로고
    • Best pharmaceuticals for children Act, S. 1789 109.
    • 107th Congress of the United States of America. Best pharmaceuticals for children Act, S. 1789 109. http://www.fda.gov/cder/pediatric/PL107-109.pdf (accessed Mar 30, 2004).
    • 107th Congress of the United States of America
  • 32
    • 0037264096 scopus 로고    scopus 로고
    • Drug research and children
    • January-February
    • US Food and Drug Administration. Drug research and children. FDA Consumer Magazine, January-February, 2003. http://www.fda.gov/fdac/features/2003/ 103_drugs.html (accessed Mar 30, 2004).
    • (2003) FDA Consumer Magazine
  • 33
    • 4244147382 scopus 로고    scopus 로고
    • Child play: Pharmaceutical firms win big on plan to test adult drugs on kids
    • Feb 5
    • Zimmerman R. Child play: pharmaceutical firms win big on plan to test adult drugs on kids. Wall Street Journal, Feb 5, 2001.
    • (2001) Wall Street Journal
    • Zimmerman, R.1
  • 34
    • 33845598736 scopus 로고    scopus 로고
    • FDAMA's Written request list: Medicines for children
    • Jong GW, van den Anker J, Choonara I. FDAMA's Written request list: medicines for children. Lancet. 357:2001;398
    • (2001) Lancet , vol.357 , pp. 398
    • Jong, G.W.1    Van Den Anker, J.2    Choonara, I.3
  • 35
    • 4444376285 scopus 로고    scopus 로고
    • United States Department of Health and Human Services. Statement by Tommy G Thompson, Secretary of Health and Human Services, and Mark B McClellan, Commissioner of Food and Drugs regarding passage of S.650: the Pediatric Research Equity Act of 2003.
    • United States Department of Health and Human Services. Statement by Tommy G Thompson, Secretary of Health and Human Services, and Mark B McClellan, Commissioner of Food and Drugs regarding passage of S.650: the Pediatric Research Equity Act of 2003. http://www.hhs.gov/news/press/2003pres/20030724. html (accessed Mar 30, 2004).
  • 37
    • 0032886561 scopus 로고    scopus 로고
    • Essential drugs for infants and children: North American perspective
    • Kauffman RE. Essential drugs for infants and children: North American perspective. Pediatrics. 104:1999;603-605
    • (1999) Pediatrics , vol.104 , pp. 603-605
    • Kauffman, R.E.1
  • 38
    • 0642341274 scopus 로고    scopus 로고
    • Minority children in pediatric research
    • Ross LF, Walsh C. Minority children in pediatric research. Am J Law Med 2003.
    • (2003) Am J Law Med
    • Ross, L.F.1    Walsh, C.2
  • 39
    • 0035488136 scopus 로고    scopus 로고
    • Balancing recruitment and protection: Children as research subjects
    • Meaux JB, Bell PL. Balancing recruitment and protection: children as research subjects. Iss Comp Pediatr Nursing. 24:2001;241-251
    • (2001) Iss Comp Pediatr Nursing , vol.24 , pp. 241-251
    • Meaux, J.B.1    Bell, P.L.2
  • 40
    • 0036916573 scopus 로고    scopus 로고
    • Paediatricians' attitudes to randomised controlled trials involving children
    • Caldwell PHY, Butow PN, Craig JC. Paediatricians' attitudes to randomised controlled trials involving children. J Pediatr. 141:2002;798-803
    • (2002) J Pediatr , vol.141 , pp. 798-803
    • Caldwell, P.H.Y.1    Butow, P.N.2    Craig, J.C.3
  • 41
    • 0031566681 scopus 로고    scopus 로고
    • Fifty years later: The significance of the Nuremburg Code
    • Shuster E. Fifty years later: the significance of the Nuremburg Code. N Engl J Med. 337:1997;1436-1440
    • (1997) N Engl J Med , vol.337 , pp. 1436-1440
    • Shuster, E.1
  • 43
    • 4444369942 scopus 로고    scopus 로고
    • Protections for children in research: A report to Congress in accord with Section 1003 of P.L. 106-310
    • Washington DC
    • Cheney R, Hastert D. Protections for children in research: a report to Congress in accord with Section 1003 of P.L. 106-310, Children's Health Act of 2000. Washington DC, 2001.
    • (2001) Children's Health Act of 2000
    • Cheney, R.1    Hastert, D.2
  • 44
    • 0036695859 scopus 로고    scopus 로고
    • The ethics of paying for children's participation in research
    • Wendler D, Rackoff JE, Emanuel EJ, Grady C. The ethics of paying for children's participation in research. J Pediatr. 141:2002;166-171
    • (2002) J Pediatr , vol.141 , pp. 166-171
    • Wendler, D.1    Rackoff, J.E.2    Emanuel, E.J.3    Grady, C.4
  • 45
    • 4444269499 scopus 로고    scopus 로고
    • Lump sums for children taking part in research may distort parents' judgement
    • Dobson R. Lump sums for children taking part in research may distort parents' judgement. BMJ. 325:2002;796
    • (2002) BMJ , vol.325 , pp. 796
    • Dobson, R.1
  • 47
    • 4444254424 scopus 로고    scopus 로고
    • The European Parliament and the Council of the European Union. Directive 2001/20/EC of the European Parliament and of the Council of Apr 4, 2001, on the approximation of the laws, regulations and administrative provisions of the Member States relating to the implementation of good clinical practice in the conduct of clinical trials on medicinal products for human use. Directive 2001/20/EC, Article 4(d), 14EN-15EN. 4-4-0001.
    • The European Parliament and the Council of the European Union. Directive 2001/20/EC of the European Parliament and of the Council of Apr 4, 2001, on the approximation of the laws, regulations and administrative provisions of the Member States relating to the implementation of good clinical practice in the conduct of clinical trials on medicinal products for human use. Directive 2001/20/EC, Article 4(d), 14EN-15EN. 4-4-0001.
  • 48
    • 0033565691 scopus 로고    scopus 로고
    • What's the price of a research subject? approaches to payment for research participation
    • Dickert N, Grady C. What's the price of a research subject? approaches to payment for research participation. N Engl J Med. 341:1999;198-203
    • (1999) N Engl J Med , vol.341 , pp. 198-203
    • Dickert, N.1    Grady, C.2
  • 50
    • 0034503543 scopus 로고    scopus 로고
    • Children as research subjects: A dilemma
    • Kopelman LM. Children as research subjects: a dilemma. J Med Philos. 25:2000;745-764
    • (2000) J Med Philos , vol.25 , pp. 745-764
    • Kopelman, L.M.1
  • 51
    • 4444222960 scopus 로고    scopus 로고
    • Institute of Medicine, Committee on Assessing the System for Protecting Human Research Participants. Responsible research. Federman D, Hanna K, Roderiguez L, eds. National Academies Press, 2003.
    • Institute of Medicine, Committee on Assessing the System for Protecting Human Research Participants. Responsible research. Federman D, Hanna K, Roderiguez L, eds. National Academies Press, 2003.
  • 52
    • 0037183012 scopus 로고    scopus 로고
    • Protecting research subjects
    • Kaufman JL. Protecting research subjects. N Engl J Med. 346:2002;2093-2095
    • (2002) N Engl J Med , vol.346 , pp. 2093-2095
    • Kaufman, J.L.1
  • 53
    • 0019511920 scopus 로고
    • Assessment of risk in research on children
    • Janofsky J, Starfield B. Assessment of risk in research on children. J Pediatr. 98:1981;842-846
    • (1981) J Pediatr , vol.98 , pp. 842-846
    • Janofsky, J.1    Starfield, B.2
  • 54
    • 0037417240 scopus 로고    scopus 로고
    • The therapeutic orientation to clinical trials
    • Miller FG, Rosenstein DL. The therapeutic orientation to clinical trials. N Engl J Med. 348:2003;1383-1386
    • (2003) N Engl J Med , vol.348 , pp. 1383-1386
    • Miller, F.G.1    Rosenstein, D.L.2
  • 56
    • 0032583827 scopus 로고    scopus 로고
    • Unlicensed and off label drug use in paediatric wards: Prospective study
    • Turner S, Longworth A, Nunn AJ, Choonara I. Unlicensed and off label drug use in paediatric wards: prospective study. BMJ. 316:1998;343-345
    • (1998) BMJ , vol.316 , pp. 343-345
    • Turner, S.1    Longworth, A.2    Nunn, A.J.3    Choonara, I.4
  • 59
    • 0028950350 scopus 로고
    • Guidelines for the ethical conduct of studies to evaluate drugs in pediatric populations
    • Committee on Drugs, American Academy of Pediatrics. Guidelines for the ethical conduct of studies to evaluate drugs in pediatric populations. Pediatrics 1995; 95: 286-94.
    • (1995) Pediatrics , vol.95 , pp. 286-294
  • 60
    • 0033129154 scopus 로고    scopus 로고
    • Pediatric drug studies: Protecting pint-sized patients
    • Nordenberg N. Pediatric drug studies: protecting pint-sized patients. FDA Consumer Magazine 33, 1999.
    • (1999) FDA Consumer Magazine , vol.33
    • Nordenberg, N.1
  • 61
    • 0033107756 scopus 로고    scopus 로고
    • Common errors of drug administration in infants: Causes and avoidance
    • Anderson BJ, Ellis JF. Common errors of drug administration in infants: causes and avoidance. Paediatr Drugs. 1:1999;93-107
    • (1999) Paediatr Drugs , vol.1 , pp. 93-107
    • Anderson, B.J.1    Ellis, J.F.2
  • 62
    • 0032885829 scopus 로고    scopus 로고
    • The Pediatric Pharmacology Research Unit (PPRU) Network and its role in meeting pediatric labeling needs
    • Cohen SN. The Pediatric Pharmacology Research Unit (PPRU) Network and its role in meeting pediatric labeling needs. Pediatrics. 104:1999;644-645
    • (1999) Pediatrics , vol.104 , pp. 644-645
    • Cohen, S.N.1
  • 63
    • 0035832567 scopus 로고    scopus 로고
    • Research with children: Paediatric practice needs better evidence - Gained in collaboration with parents and children
    • Smyth RL. Research with children: paediatric practice needs better evidence - gained in collaboration with parents and children. BMJ. 322:2001;1377-1378
    • (2001) BMJ , vol.322 , pp. 1377-1378
    • Smyth, R.L.1
  • 64
    • 0031880145 scopus 로고    scopus 로고
    • A review of randomised controlled trials published in Archives of Disease in Childhood from 1982-96
    • Campbell H, Surry SAM, Royle EM. A review of randomised controlled trials published in Archives of Disease in Childhood from 1982-96. Arch Dis Child. 79:1998;192-197
    • (1998) Arch Dis Child , vol.79 , pp. 192-197
    • Campbell, H.1    Surry, S.A.M.2    Royle, E.M.3
  • 65
    • 0035956480 scopus 로고    scopus 로고
    • Salmeterol and inhaled corticosteroids in patients with persistent asthma
    • Ross LF. Salmeterol and inhaled corticosteroids in patients with persistent asthma. JAMA. 286:2001;3076
    • (2001) JAMA , vol.286 , pp. 3076
    • Ross, L.F.1
  • 66
    • 0030594248 scopus 로고    scopus 로고
    • Re: Recruiting minorities into clinical trials: Toward a participant-friendly system
    • Bleyer WA. Re: recruiting minorities into clinical trials: toward a participant-friendly system. J Natl Cancer Inst. 88:1996;377
    • (1996) J Natl Cancer Inst , vol.88 , pp. 377
    • Bleyer, W.A.1
  • 67
    • 0025727297 scopus 로고
    • Group meetings for recruitment of children in a clinical trial
    • Collet JP, Floret D, Cochat P, et al. Group meetings for recruitment of children in a clinical trial. Therapie. 46:1991;139-142
    • (1991) Therapie , vol.46 , pp. 139-142
    • Collet, J.P.1    Floret, D.2    Cochat, P.3
  • 68
    • 0028813641 scopus 로고
    • Intensification of treatment and survival in all children with lymphoblastic leukemia: Results of UK Medical Research Council trial UKALL X
    • Chessells JM, Bailey C, Richards SM. Intensification of treatment and survival in all children with lymphoblastic leukemia: results of UK Medical Research Council trial UKALL X. Lancet. 345:1995;143-148
    • (1995) Lancet , vol.345 , pp. 143-148
    • Chessells, J.M.1    Bailey, C.2    Richards, S.M.3
  • 69
    • 0028881924 scopus 로고
    • Parental perceptions and attitudes about informed consent in clinical research involving children
    • Harth SC, Thong YH. Parental perceptions and attitudes about informed consent in clinical research involving children. Soc Sci Med. 41:1995;1647-1651
    • (1995) Soc Sci Med , vol.41 , pp. 1647-1651
    • Harth, S.C.1    Thong, Y.H.2
  • 70
    • 0028037136 scopus 로고
    • Behavioral aspects of clinical trials: An integrated framework from behavior theory
    • Morrow GR, Hickok JT, Burish TG. Behavioral aspects of clinical trials: an integrated framework from behavior theory. Cancer. 74:(suppl 9):1994;2676-2682
    • (1994) Cancer , vol.74 , Issue.SUPPL. 9 , pp. 2676-2682
    • Morrow, G.R.1    Hickok, J.T.2    Burish, T.G.3
  • 71
    • 0023550323 scopus 로고
    • Interpreting physician participation in randomized clinical trials: The Physician Orientation Profile
    • Taylor KM, Kelner M. Interpreting physician participation in randomized clinical trials: the Physician Orientation Profile. J Health Soc Behav. 28:1987;389-400
    • (1987) J Health Soc Behav , vol.28 , pp. 389-400
    • Taylor, K.M.1    Kelner, M.2
  • 72
    • 0031409279 scopus 로고    scopus 로고
    • Clinicians' attitudes to clinical trials of cancer therapy
    • Fallowfield L, Ratcliffe D, Souhami R. Clinicians' attitudes to clinical trials of cancer therapy. Eur J Cancer. 33:1997;2221-2229
    • (1997) Eur J Cancer , vol.33 , pp. 2221-2229
    • Fallowfield, L.1    Ratcliffe, D.2    Souhami, R.3
  • 73
    • 0026636643 scopus 로고
    • Integrating conflicting professional roles: Physician participation in randomized clinical trials
    • Taylor KM. Integrating conflicting professional roles: physician participation in randomized clinical trials. Soc Sci Med. 35:1992;217-224
    • (1992) Soc Sci Med , vol.35 , pp. 217-224
    • Taylor, K.M.1
  • 74
    • 0027169595 scopus 로고
    • Factors affecting general practitioners' recruitment of patients into a prospective study
    • Peto V, Coulter A, Bond A. Factors affecting general practitioners' recruitment of patients into a prospective study. Fam Pract. 10:1993;207-211
    • (1993) Fam Pract , vol.10 , pp. 207-211
    • Peto, V.1    Coulter, A.2    Bond, A.3
  • 75
    • 0032978081 scopus 로고    scopus 로고
    • Recruiting minority cancer patients into cancer clinical trials: A pilot project involving the Eastern Cooperative Oncology Group and the National Medical Association
    • McCaskill-Stevens W, Pinto H, Marcus AC, et al. Recruiting minority cancer patients into cancer clinical trials: a pilot project involving the Eastern Cooperative Oncology Group and the National Medical Association. J Clin Oncol. 17:1999;1029-1039
    • (1999) J Clin Oncol , vol.17 , pp. 1029-1039
    • McCaskill-Stevens, W.1    Pinto, H.2    Marcus, A.C.3
  • 76
    • 0021339672 scopus 로고
    • Physicians' reasons for not entering eligible patients in a randomized clinical trial of surgery for breast cancer
    • Taylor KM, Margolese RG, Soskolne CL. Physicians' reasons for not entering eligible patients in a randomized clinical trial of surgery for breast cancer. N Engl J Med. 310:1984;1363-1367
    • (1984) N Engl J Med , vol.310 , pp. 1363-1367
    • Taylor, K.M.1    Margolese, R.G.2    Soskolne, C.L.3
  • 77
    • 0021817891 scopus 로고
    • The doctor's dilemma: Physician participation in randomized clinical trials
    • Taylor KM. The doctor's dilemma: physician participation in randomized clinical trials. Cancer Treat Rep. 69:1985;1095-1100
    • (1985) Cancer Treat Rep , vol.69 , pp. 1095-1100
    • Taylor, K.M.1
  • 78
    • 0026428131 scopus 로고
    • Viability of cancer clinical research: Patient accrual, coverage, and reimbursement
    • American Medical Association Council on Scientific Affairs
    • Anon. Viability of cancer clinical research: patient accrual, coverage, and reimbursement. American Medical Association Council on Scientific Affairs. J Natl Cancer Inst 1991; 83: 0254-59.
    • (1991) J Natl Cancer Inst , vol.83 , pp. 0254-0259
  • 79
    • 0034116015 scopus 로고    scopus 로고
    • Factors that predict the referral of breast cancer patients onto clinical trials by their surgeons and medical oncologists
    • Siminoff LA, Zhang A, Colabianchi N, Sturm CM, Shen Q. Factors that predict the referral of breast cancer patients onto clinical trials by their surgeons and medical oncologists. J Clin Oncol. 18:2000;1203-1211
    • (2000) J Clin Oncol , vol.18 , pp. 1203-1211
    • Siminoff, L.A.1    Zhang, A.2    Colabianchi, N.3    Sturm, C.M.4    Shen, Q.5
  • 80
    • 0032985608 scopus 로고    scopus 로고
    • Barriers to participation in randomized clinical trials for early breast cancer among Australian cancer specialists
    • Ellis PM, Butow PN, Simes RJ, Tattersall MHN, Dunn SM. Barriers to participation in randomized clinical trials for early breast cancer among Australian cancer specialists. Aust N Z J Surg. 69:1999;486-491
    • (1999) Aust N Z J Surg , vol.69 , pp. 486-491
    • Ellis, P.M.1    Butow, P.N.2    Simes, R.J.3    Tattersall, M.H.N.4    Dunn, S.M.5
  • 81
    • 0026918984 scopus 로고
    • Physician participation in a randomized clinical trial for ocular melanoma
    • Taylor KM. Physician participation in a randomized clinical trial for ocular melanoma. Ann Ophthalmol. 24:1992;337-344
    • (1992) Ann Ophthalmol , vol.24 , pp. 337-344
    • Taylor, K.M.1
  • 82
    • 0023656185 scopus 로고
    • Physician response to informed consent regulations for randomized clinical trials
    • Taylor KM, Shapiro M, Soskolne CL, Margolese RG. Physician response to informed consent regulations for randomized clinical trials. Cancer. 60:1987;1415-1422
    • (1987) Cancer , vol.60 , pp. 1415-1422
    • Taylor, K.M.1    Shapiro, M.2    Soskolne, C.L.3    Margolese, R.G.4
  • 83
    • 0026094298 scopus 로고
    • Oncologists' reluctance to accrue patients onto clinical trials: An Illinois Cancer Center study
    • Benson AB, Pregler JP, Bean JA, Rademaker AW, Eshler B, Anderson K. Oncologists' reluctance to accrue patients onto clinical trials: an Illinois Cancer Center study. J Clin Oncol. 9:1991;2067-2075
    • (1991) J Clin Oncol , vol.9 , pp. 2067-2075
    • Benson, A.B.1    Pregler, J.P.2    Bean, J.A.3    Rademaker, A.W.4    Eshler, B.5    Anderson, K.6
  • 84
    • 0025652032 scopus 로고
    • Prerandomization: An alternative to classic randomization - The effects on recruitment in a controlled trial of arthroscopy for osteoarthrosis of the knee
    • Chang RW, Falconer J, Stulberg SD, Arnold WJ, Dyer AR. Prerandomization: an alternative to classic randomization - the effects on recruitment in a controlled trial of arthroscopy for osteoarthrosis of the knee. J Bone Joint Surg Am. 72:1990;1451-1455
    • (1990) J Bone Joint Surg Am , vol.72 , pp. 1451-1455
    • Chang, R.W.1    Falconer, J.2    Stulberg, S.D.3    Arnold, W.J.4    Dyer, A.R.5
  • 85
    • 0028791332 scopus 로고
    • Recruiting minorities into clinical trials: Toward a participant-friendly system
    • Swanson GM, Ward AJ. Recruiting minorities into clinical trials: toward a participant-friendly system. J Natl Cancer Inst. 87:1995;1747-1759
    • (1995) J Natl Cancer Inst , vol.87 , pp. 1747-1759
    • Swanson, G.M.1    Ward, A.J.2
  • 86
    • 0028130499 scopus 로고
    • Fundamental dilemmas of the randomized clinical trial process: Results of a survey of the 1,737 Eastern Cooperative Oncology Group investigators
    • Taylor KM, Feldstein ML, Skeel RT, Pandya KJ, Ng P, Carbone PP. Fundamental dilemmas of the randomized clinical trial process: results of a survey of the 1,737 Eastern Cooperative Oncology Group investigators. J Clin Oncol. 12:1994;1796-1805
    • (1994) J Clin Oncol , vol.12 , pp. 1796-1805
    • Taylor, K.M.1    Feldstein, M.L.2    Skeel, R.T.3    Pandya, K.J.4    Ng, P.5    Carbone, P.P.6
  • 87
    • 0025016965 scopus 로고
    • Informed consent: Influence on patient selection among critically ill premature infants
    • Walterspiel JN. Informed consent: influence on patient selection among critically ill premature infants. Pediatrics. 85:1990;119-121
    • (1990) Pediatrics , vol.85 , pp. 119-121
    • Walterspiel, J.N.1
  • 88
    • 0141543854 scopus 로고    scopus 로고
    • Participation of children in clinical research, factors that influence a parent's decision to consent
    • Tait AR, Voepel-Lewis T, Malviya S. Participation of children in clinical research, factors that influence a parent's decision to consent. Anesthesiology. 99:2003;819-825
    • (2003) Anesthesiology , vol.99 , pp. 819-825
    • Tait, A.R.1    Voepel-Lewis, T.2    Malviya, S.3
  • 89
    • 0030622486 scopus 로고    scopus 로고
    • Determinants of parental authorization for involvement of newborn infants in clinical trials
    • Zupancic JAF, Gillie P, Streiner DL, Watts JL, Schmidt B. Determinants of parental authorization for involvement of newborn infants in clinical trials. Pediatrics. 99:1997;E6
    • (1997) Pediatrics , vol.99 , pp. 6
    • Zupancic, J.A.F.1    Gillie, P.2    Streiner, D.L.3    Watts, J.L.4    Schmidt, B.5
  • 90
    • 0031951175 scopus 로고    scopus 로고
    • Parental willingness to enter a child in a controlled vaccine trial
    • Langley JM, Halperin SA, Mills EL, Eastwood B. Parental willingness to enter a child in a controlled vaccine trial. Med Clin Exp. 21:1998;12-16
    • (1998) Med Clin Exp , vol.21 , pp. 12-16
    • Langley, J.M.1    Halperin, S.A.2    Mills, E.L.3    Eastwood, B.4
  • 91
    • 0033001058 scopus 로고    scopus 로고
    • Recruitment of participants in the childhood asthma management program (CAMP). I. Description of methods
    • Childhood Asthma Management Program Research Group. Recruitment of participants in the childhood asthma management program (CAMP). I. Description of methods. J Asthma 1999; 36: 217-37.
    • (1999) J Asthma , vol.36 , pp. 217-237
  • 93
    • 0026101907 scopus 로고
    • The social filter effect of informed consent in clinical research
    • Thong YH, Harth SC. The social filter effect of informed consent in clinical research. Pediatrics. 87:1991;568-569
    • (1991) Pediatrics , vol.87 , pp. 568-569
    • Thong, Y.H.1    Harth, S.C.2
  • 94
    • 0030039783 scopus 로고    scopus 로고
    • Is informed consent in neonatal randomised controlled trials ritual?
    • Levene M, Wright I, Griffiths G. Is informed consent in neonatal randomised controlled trials ritual? Lancet. 347:1996;475
    • (1996) Lancet , vol.347 , pp. 475
    • Levene, M.1    Wright, I.2    Griffiths, G.3
  • 96
    • 2642620566 scopus 로고    scopus 로고
    • Offering a randomized trial of intensive therapy for IDDM to adolescents. Reasons for refusal, patient characteristics, and recruiter effects
    • Tercyak KPJ, Johnson SB, Kirkpatrick KA, Silverstein JH. Offering a randomized trial of intensive therapy for IDDM to adolescents. Reasons for refusal, patient characteristics, and recruiter effects. Diabetes Care. 21:1998;213-215
    • (1998) Diabetes Care , vol.21 , pp. 213-215
    • Tercyak, K.P.J.1    Johnson, S.B.2    Kirkpatrick, K.A.3    Silverstein, J.H.4
  • 97
    • 0037373103 scopus 로고    scopus 로고
    • Do they understand? (Part 1), Parental consent for children participating in clinical anesthesia and surgery research
    • Tait AR, Voepel-Lewis T, Malviya S. Do they understand? (Part 1), Parental consent for children participating in clinical anesthesia and surgery research. Anesthesiol. 98:2003;603-608
    • (2003) Anesthesiol , vol.98 , pp. 603-608
    • Tait, A.R.1    Voepel-Lewis, T.2    Malviya, S.3
  • 98
    • 0030839611 scopus 로고    scopus 로고
    • Making sense of randomization; Responses of parents of critically ill babies to random allocation of treatment in a clinical trial
    • Snowdon C, Garcia J, Elbourne D. Making sense of randomization; responses of parents of critically ill babies to random allocation of treatment in a clinical trial. Soc Sci Med. 45:1997;1337-1355
    • (1997) Soc Sci Med , vol.45 , pp. 1337-1355
    • Snowdon, C.1    Garcia, J.2    Elbourne, D.3
  • 99
    • 0032879579 scopus 로고    scopus 로고
    • Parents' perceptions of randomization in pediatric clinical trials
    • Wiley FM, Ruccione K, Moore IM, et al. Parents' perceptions of randomization in pediatric clinical trials. Cancer Pract. 7:1999;248-256
    • (1999) Cancer Pract , vol.7 , pp. 248-256
    • Wiley, F.M.1    Ruccione, K.2    Moore, I.M.3
  • 100
    • 0032585195 scopus 로고    scopus 로고
    • Random allocation or allocation at random? patients' perspectives of participation in a randomised controlled trial
    • Featherstone K, Donovan JL. Random allocation or allocation at random? patients' perspectives of participation in a randomised controlled trial. BMJ. 317:2002;1177-1180
    • (2002) BMJ , vol.317 , pp. 1177-1180
    • Featherstone, K.1    Donovan, J.L.2
  • 101
    • 0033599791 scopus 로고    scopus 로고
    • Is recruitment more difficult with a placebo arm in randomised controlled trials? a quasirandomised, interview based study
    • Welton AJ, Vickers MR, Cooper JA, Meade TW, Marteau TM. Is recruitment more difficult with a placebo arm in randomised controlled trials? A quasirandomised, interview based study. BMJ. 318:1999;1114-1117
    • (1999) BMJ , vol.318 , pp. 1114-1117
    • Welton, A.J.1    Vickers, M.R.2    Cooper, J.A.3    Meade, T.W.4    Marteau, T.M.5
  • 102
    • 0036042898 scopus 로고    scopus 로고
    • Physicians' preferences for active-controlled versus placebo-controlled trials of new antihypertensive drugs
    • Halpern SD, Ubel PA, Berlin JA, Townsend RR, Asch DA. Physicians' preferences for active-controlled versus placebo-controlled trials of new antihypertensive drugs. J Gen Intern Med. 17:2002;689-695
    • (2002) J Gen Intern Med , vol.17 , pp. 689-695
    • Halpern, S.D.1    Ubel, P.A.2    Berlin, J.A.3    Townsend, R.R.4    Asch, D.A.5
  • 103
    • 0031950501 scopus 로고    scopus 로고
    • Informed consent, parental awareness, and reasons for participating in a randomised controlled study
    • van Stuijvenberg M, Suur MH, de Vos S, et al. Informed consent, parental awareness, and reasons for participating in a randomised controlled study. Arch Dis Child. 79:1998;120-125
    • (1998) Arch Dis Child , vol.79 , pp. 120-125
    • Van Stuijvenberg, M.1    Suur, M.H.2    De Vos, S.3
  • 104
    • 0025157233 scopus 로고
    • Readability of pediatric biomedical research informed consent forms
    • Tarnowski KJ, Allen DM, Mayall C, Kelly PA. Readability of pediatric biomedical research informed consent forms. Pediatrics. 85:1990;58-62
    • (1990) Pediatrics , vol.85 , pp. 58-62
    • Tarnowski, K.J.1    Allen, D.M.2    Mayall, C.3    Kelly, P.A.4
  • 105
    • 0025094328 scopus 로고
    • Trends in survival for childhood cancer in Britian diagnosed 1971-85
    • Stiller CA, Bunch KJ. Trends in survival for childhood cancer in Britian diagnosed 1971-85. Br J Cancer. 62:1990;806-815
    • (1990) Br J Cancer , vol.62 , pp. 806-815
    • Stiller, C.A.1    Bunch, K.J.2
  • 107
    • 0030044423 scopus 로고    scopus 로고
    • Childhood cancer in the United States: A geographical analysis of cases from the pediatric cooperative clinical trials groups
    • Ross JA, Severson RK, Pollock BH, Robison LL. Childhood cancer in the United States: a geographical analysis of cases from the pediatric cooperative clinical trials groups. Cancer. 77:1996;201-207
    • (1996) Cancer , vol.77 , pp. 201-207
    • Ross, J.A.1    Severson, R.K.2    Pollock, B.H.3    Robison, L.L.4
  • 108
    • 0028899165 scopus 로고
    • The national impact of Clinical Cooperative Group Trials for pediatric cancer
    • Murphy SB. The national impact of Clinical Cooperative Group Trials for pediatric cancer. Med Pediatr Oncol. 24:1995;279-280
    • (1995) Med Pediatr Oncol , vol.24 , pp. 279-280
    • Murphy, S.B.1
  • 109
    • 0035691113 scopus 로고    scopus 로고
    • Cancer clinical trials: Risks and benefits
    • Murphy SB. Cancer clinical trials: risks and benefits. J Pediatr Hematol Oncol. 3:2001;546-567
    • (2001) J Pediatr Hematol Oncol , vol.3 , pp. 546-567
    • Murphy, S.B.1
  • 110
    • 0033391948 scopus 로고    scopus 로고
    • Improving recruitment to cancer clinical trials
    • Ellis P. Improving recruitment to cancer clinical trials. Cancer Forum. 23:1999;153-155
    • (1999) Cancer Forum , vol.23 , pp. 153-155
    • Ellis, P.1
  • 111
    • 0031697779 scopus 로고    scopus 로고
    • The evolution of cancer care for children and adults
    • Simone JV, Lyons J. The evolution of cancer care for children and adults. J Clin Oncol. 7:1998;2904-2905
    • (1998) J Clin Oncol , vol.7 , pp. 2904-2905
    • Simone, J.V.1    Lyons, J.2
  • 112
    • 4444281141 scopus 로고    scopus 로고
    • The Medical Research Council General Practice Research Framework. http://www.mrc-gprf.ac.uk (accessed April, 2004).
  • 113
    • 4444381529 scopus 로고    scopus 로고
    • The Central Institutional Review Board Initiative.
    • National Cancer Institute. The Central Institutional Review Board Initiative. http://www.ncicirb.org (accessed Mar 30, 2004).


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