Does placement of a connective tissue graft improve the outcomes of coronally advanced flap for coverage of single gingival recessions in upper anterior teeth? A multi-centre, randomized, double-blind, clinical trial

Journal of Clinical Periodontology

Volumn 36, Issue 1, 2009, Pages 68-79

  Cortellini, Pierpaolo ^a,b,e   Tonetti, Maurizio ^b   Baldi, Carlo ^c   Francetti, Luca ^d   Rasperini, Giulio ^d   Rotundo, Roberto ^c   Nieri, Michele ^c   Franceschi, Debora ^c   Labriola, Antonella ^c   Pini Prato, Giovanpaolo ^c  

^a Accademia Toscana di Ricerca Odontostomatologica   (Italy)

^b European Research Group on Periodontology ERGOPerio   (Switzerland)

^c UNIVERSITY OF FLORENCE   (Italy)

^d UNIVERSITY OF MILAN   (Italy)

^e NONE   (Italy)

Author keywords

Clinical trial; Gingival recession; Periodontal surgery; Root coverage

Indexed keywords

ADULT; ARTICLE; CANINE TOOTH; CLASSIFICATION; CLINICAL TRIAL; CONNECTIVE TISSUE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; FOLLOW UP; GINGIVA DISEASE; GINGIVOPLASTY; HUMAN; INCISOR; MAXILLA; METHODOLOGY; MIDDLE AGED; MULTICENTER STUDY; MULTIMODALITY CANCER THERAPY; PLASTIC SURGERY; RANDOMIZED CONTROLLED TRIAL; TOOTH CROWN; TOOTH ROOT; TRANSPLANTATION; TREATMENT OUTCOME;

ADULT; COMBINED MODALITY THERAPY; CONNECTIVE TISSUE; CUSPID; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; GINGIVAL RECESSION; GINGIVOPLASTY; HUMANS; INCISOR; MAXILLA; MIDDLE AGED; SURGICAL FLAPS; TOOTH CROWN; TOOTH ROOT; TREATMENT OUTCOME;

EID: 58449090086     PISSN: 03036979     EISSN: 1600051X     Source Type: Journal    
DOI: 10.1111/j.1600-051X.2008.01346.x     Document Type: Article

References (43)

1. Aichelmann-Reidy, M. E., Yukna, R. A., Evans, G. H., Nasr, H. F. Mayer, E. T. (2001) Clinical evaluation of acellular allograft dermis for the treatment of human gingival recession. Journal of Periodontology 72, 998 1005.
2. Allen, E. P. Miller, P. D. (1989) Coronal positioning of existing gingiva. Short term results in the treatment of shallow marginal tissue recession. Journal of Periodontology 60, 316 319.
3. Andrade, P. F., Felipe, M. E., Novaes, A. B. Jr., Souza, S. L., Taba, M. Jr., Palioto, D. B. Grisi, M. F. (2008) Comparison between two surgical techniques for root coverage with an acellular dermal matrix graft. Journal of Clinical Periodontology 35, 263 269.
4. Cairo, F., Pagliaro, U. Nieri, M. (2008) Treatment of gingival recession with coronally advanced flap procedures. A systematic review. Journal of Clinical Periodontology 35 (Suppl.), 141 167.
5. Castellanos, A. T., de la Rosa, M. R., de la Garza, M. Caffesse, R. G. (2006) Enamel matrix derivative and coronal flaps to cover marginal tissue recessions. Journal of Periodontology 77, 7 14.
6. Clauser, C., Nieri, M., Franceschi, D., Pagliaro, U. Pini-Prato, G. (2003) Evidence-based mucogingival therapy. Part 2: ordinary and individual patient data meta-analyses of surgical treatment of recession using complete root coverage as the outcome variable. Journal of Periodontology 74, 741 756.
7. Cortellini, P., Tonetti, M. S., Lang, N.P, Suvan, J. E., Zucchelli, G., Vangsted, T., Silvestri, M., Rossi, R., McClain, P., Fonzar, A., Dubravec, D. Adriaens, P. (2001) The simplified papilla preservation flap in the regenerative treatment of deep intrabony defects: clinical outcomes and postoperative morbidity. Journal of Periodontology 72, 1702 1712.
8. Côrtes Ade, Q., Martins, A. G., Nociti, F. H. Jr., Sallum, A. W., Casati, M. Z. Sallum, E. A. (2004) Coronally positioned flap with or without acellular dermal matrix graft in the treatment of Class I gingival recessions: a randomized controlled clinical study. Journal of Periodontology 75, 1137 1144.
9. da Silva, R. C., Joly, J. C., de Lima, A. F. Tatakis, D. N. (2004) Root coverage using the coronally positioned flap with or without a subepithelial connective tissue graft. Journal of Periodontology 75, 413 419.
10. Del Pizzo, M., Zucchelli, G., Modica, F., Villa, R. Debernardi, C. (2005) Coronally advanced flap with or without enamel matrix derivative for root coverage: a 2-year study. Journal of Clinical Periodontology 32, 1181 1187.
11. Dentino, A. R., Derderian, G., Wolf, M., Cugini, M., Johnson, R., Van Swol, R. L., King, D., Marks, P. Warren, P. (2002) Six-month comparison of powered versus manual toothbrushing for safety and efficacy in the absence of professional instruction in mechanical plaque control. Journal of Periodontology 73, 770 778.
12. de Queiroz Côrtes, A., Sallum, A. W., Casati, M. Z., Nociti, F. H. Jr. Sallum, E. A. (2006) A two-year prospective study of coronally positioned flap with or without acellular dermal matrix graft. Journal of Clinical Periodontology 33, 683 689.
13. de Sanctis, M. Zucchelli, G. (2007) Coronally advanced flap: a modified surgical approach for isolated recession-type defects: three-year results. Journal of Clinical Periodontology 34, 262 268.
14. Dupont, W. D. Plummer, W. D. Jr. (1990) Power and sample size calculations: a review and computer program. Controlled Clinical Trials 11, 116 128.
15. Harris, R. (2000) A comparative study of root coverage obtained with an acellular dermal matrix versus a connective tissue graft: results of 107 recession defects in 50 consecutively treated patients. International Journal of Periodontics and Restorative Dentistry 20, 51 59.
16. Hugoson, A., Sjödin, B. Norderyd, O. (2008) Trends over 30 years, 1973-2003, in the prevalence and severity of periodontal disease. Journal of Clinical Periodontology 35, 405 414.
17. Hyman, J. (2006) The importance of assessing confounding and effect modification in research involving periodontal disease and systemic diseases. Journal of Clinical Periodontology 33, 102 103.
18. Joly, J. C., Carvalho, A. M., da Silva, R. C., Ciotti, D. L. Cury, P. R. (2007) Root coverage in isolated gingival recessions using autograft versus allograft: a pilot study. Journal of Periodontology 78, 1017 1022.
19. Keceli, H. G., Sengun, D., Berberoǧlu, A. Karabulut, E. (2008) Use of platelet gel with connective tissue grafts for root coverage: a randomized-controlled trial. Journal of Clinical Periodontology 35, 255 262.
20. Kerner, S., Borghetti, A., Katsahian, S., Etienne, D., Malet, J., Mora, F., Monnet-Corti, V., Glise, J. M. Bouchard, P. (2008) A retrospective study of root coverage procedures using an image analysis system. Journal of Clinical Periodontology 35, 346 355.
21. Langer, B. Langer, L. (1985) Subepithelial connective tissue graft technique for root coverage. Journal of Periodontology 56, 715 720.
22. McGuire, M. K. Nunn, M. (2003) Evaluation of human recession defects treated with coronally advanced flaps and either enamel matrix derivative or connective tissue. Part 1: comparison of clinical parameters. Journal of Periodontology 74, 1110 1125.
23. Miller, P. D. (1985) A classification of marginal tissue recession. International Journal of Periodontics and Restorative Dentistry 5, 8 13.
24. Oates, T. W., Robinson, M. Gunsolley, J. C. (2003) Surgical therapies for the treatment of gingival recession. A systematic review. Annals of Periodontology 8, 303 320.
25. Patters, M. R., Bland, P.S, Shiloah, J., Blankenship, J.A Scarbecz, M. (2005) Comparison of the hydrabrush powered toothbrush with two commercially-available powered toothbrushes. Journal of International Academic Periodontology 7, 80 89.
26. Pilloni, A., Paolantonio, M. Camargo, P. M. (2006) Root coverage with coronally positioned flap used in combination with enamel matrix derivative: 18-month clinical evaluation. Journal of Periodontology 77, 2031 2039.
27. Pini Prato, G. P., Baldi, C., Nieri, M., Franceschi, D., Cortellini, P., Clauser, C., Rotundo, R. Muzzi, L. (2005) Coronally advanced flap: the post-surgical position of the gingival margin is an important factor for achieving complete root coverage. Journal of Periodontology 76, 713 722.
28. Pini Prato, G., Pagliaro, U., Baldi, C., Nieri, M., Saletta, D., Cairo, F. Cortellini, P. (2000) Coronally advanced flap procedure for root coverage. Flap with tension versus flap without tension: a randomized controlled clinical study. Journal of Periodontology 71, 188 201.
29. Pini Prato, G., Tinti, C., Vincenzi, G., Magnani, C., Cortellini, P. Clauser, C. (1992) Guided tissue regeneration versus mucogingival surgery in the treatment of human buccal gingival recession. Journal of Periodontology 63, 919 928.
30. Rajapakse, P. S., McCracken, G. I., Gwynnett, E., Steen, N. D., Guentsch, A. Heasman, P. A. (2007) Does tooth brushing influence the development and progression of non-inflammatory gingival recession? A systematic review. Journal of Clinical Periodontology 34, 1046 1061.
31. Rasperini, G., Silvestri, M., Schenk, R. K. Nevins, M. L. (2000) Clinical and histologic evaluation of human gingival recession treated with a subepithelial connective tissue graft and enamel matrix derivative (Emdogain): a case report. International Journal of Periodontics and Restorative Dentistry 20, 269 275.
32. Robinson, P. G., Deacon, S. A., Deery, C., Heanue, M., Walmsley, A. D., Worthington, H. V., Glenny, A. M. Shaw, W. C. (2007) Manual versus powered toothbrushing for oral health. Cochrane Database of Systematic Reviews, issue 4.
33. Roccuzzo, M., Bunino, M., Needleman, I. Sanz, M. (2002) Periodontal plastic surgery for treatment of localized gingival recessions: a systematic review. Journal of Clinical Periodontology 29 (Suppl. 3), 178 194.
34. Roccuzzo, M., Lungo, M., Corrente, G. Gandolfo, S. (1996) Comparative study of a bioresorbable and a non-resorbable membrane in the treatment of human buccal gingival recessions. Journal of Periodontology 67, 7 14.
35. Röthlisberger, B., Kuonen, P., Salvi, G. E., Gerber, J., Pjetursson, B. E., Attström, R., Joss, A. Lang, N. P. (2007) Periodontal conditions in Swiss army recruits: a comparative study between the years 1985, 1996 and 2006. Journal of Clinical Periodontology 34, 860 866.
36. Spahr, A., Haegewald, S., Tsoulfidou, F., Rompola, E. Heijl, L. (2005) Coverage of Miller class I and II recession defects using enamel matrix proteins versus coronally advanced flap technique: a 2-year report. Journal of Periodontology 76, 1871 1880.
37. Sullivan, H. C. Atkins, J. H. (1968) Free autogenous gingival grafts. 3. Utilization of grafts in the treatment of gingival recession. Periodontics 6, 152 160.
38. Tonetti, M., Cortellini, P., Suvan, J. E., Adriaens, P., Baldi, C., Dubravec, D., Fonzar, A., Fourmosis, I., Magnani, C., Muller-Campanile, V., Patroni, S., Sanz, M., Vangsted, T., Zabalegui, I., Pini Prato, G. Lang, N. P. (1998) Generalizability of the added benefits of guided tissue regeneration in the treatment of deep intrabony defects. Evaluation in a multi-center randomized controlled clinical trial. Journal of Periodontology 69, 1183 1192.
39. Tonetti, M. S., Fourmousis, I., Suvan, J., Cortellini, P., Bragger, U. Lang, N. P. (2004) Healing, post-operative morbidity and patient perception of outcomes following regenerative therapy of deep intrabony defects. Journal of Clinical Periodontology 31, 1092 1098.
40. Tonetti, M. S., Lang, N. P., Cortellini, P., Suvan, J. E., Adriaens, P., Dubravec, D., Fonzar, A., Fourmousis, J., Mayfield, L., Rossi, R., Silvestri, M., Tiedemann, C., Topoll, H., Vangsted, T. Walkamm, B. (2002) Enamel matrix proteins I the regenerative therapy of deep intrabony defects. A multicenter randomized controlled clinical trial. Journal of Clinical Periodontology 29, 317 325.
41. Vandekerchkove, B., Quirynen, M., Warren, P. R., Strate, J. van Steenberghe, D. (2004) The safety and efficacy of a powered toothbrush on soft tissues in patients with implant-supported fixed prostheses. Clinical Oral Investigation 8, 206 210.
42. Yates, R. J., Newcombe, R. G. Addy, M. (2004) Dentine hypersensitivity: a randomised, double-blind placebo-controlled study of the efficacy of a fluoride-sensitive teeth mouthrinse. Journal of Clinical Periodontology 31, 885 889.
43. Zucchelli, G., Amore, C., Sforza, N. M., Montebugnoli, L. De Sanctis, M. (2003) Bilaminar techniques for the treatment of recession-type defects. A comparative clinical study. Journal of Clinical Periodontology 30, 862 870.