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Volumn 42, Issue 1, 2009, Pages 1-9

TGFβ inhibits GM-CSF-induced phosphorylation of ERK and MEK in human myeloid leukaemia cell lines via inhibition of phosphatidylinositol 3-kinase (PI3-k)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PHOSPHATIDYLINOSITOL 3 KINASE; TRANSFORMING GROWTH FACTOR BETA; MITOGEN ACTIVATED PROTEIN KINASE; RECOMBINANT PROTEIN;

EID: 58449087955     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/j.1365-2184.2008.00567.x     Document Type: Article
Times cited : (15)

References (33)
  • 1
    • 0027374766 scopus 로고
    • TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest
    • Ewen ME, Sluss HK, Whitehouse LL, Livingston DM (1993) TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest. Cell 74, 1009 1020.
    • (1993) Cell , vol.74 , pp. 1009-1020
    • Ewen, M.E.1    Sluss, H.K.2    Whitehouse, L.L.3    Livingston, D.M.4
  • 2
    • 0023029023 scopus 로고
    • Transforming growth factor-beta is an important immunomodulatory protein for human B lymphocytes
    • Kehrl JH, Roberts AB, Wakefield LM, Jakowlew S, Sporn MB, Fauci AS (1986) Transforming growth factor-beta is an important immunomodulatory protein for human B lymphocytes. J. Immunol. 137, 3855 3860.
    • (1986) J. Immunol. , vol.137 , pp. 3855-3860
    • Kehrl, J.H.1    Roberts, A.B.2    Wakefield, L.M.3    Jakowlew, S.4    Sporn, M.B.5    Fauci, A.S.6
  • 3
    • 0023625418 scopus 로고
    • Evidence that transforming growth factor-beta is a hormonally regulated negative growth factor in human breast cancer cells
    • Knabbe C, Lippman ME, Wakefield LM, Flanders KC, Kasid A (1987) Evidence that transforming growth factor-beta is a hormonally regulated negative growth factor in human breast cancer cells. Cell 48, 417 428.
    • (1987) Cell , vol.48 , pp. 417-428
    • Knabbe, C.1    Lippman, M.E.2    Wakefield, L.M.3    Flanders, K.C.4    Kasid, A.5
  • 4
    • 11844263366 scopus 로고    scopus 로고
    • Transforming growth factor-beta, cell signaling and cardiovascular disorders
    • Agrotis A, Kalinina N, Bobik A (2005) Transforming growth factor-beta, cell signaling and cardiovascular disorders. Curr. Vasc Pharmacol. 3, 55 61.
    • (2005) Curr. Vasc Pharmacol. , vol.3 , pp. 55-61
    • Agrotis, A.1    Kalinina, N.2    Bobik, A.3
  • 5
    • 0032929017 scopus 로고    scopus 로고
    • Transforming growth factor-β (TGFβ) inhibits growth of more differentiated myeloid leukemia cells and retinoblastoma protein phosphorylation at Ser795
    • Hu X, Moscinski LC, Zuckerman KS (1999) Transforming growth factor-β (TGFβ) inhibits growth of more differentiated myeloid leukemia cells and retinoblastoma protein phosphorylation at Ser795. Exp Hematol. 27, 605 614.
    • (1999) Exp Hematol. , vol.27 , pp. 605-614
    • Hu, X.1    Moscinski, L.C.2    Zuckerman, K.S.3
  • 6
    • 0031034589 scopus 로고    scopus 로고
    • Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway
    • Nakao A, Roijer E, Imamura T, Souchelnytskyi S, Stenman G, Heldin CH et al 1997) Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway. J. Biol. Chem. 272, 2896 2900.
    • (1997) J. Biol. Chem. , vol.272 , pp. 2896-2900
    • Nakao, A.1    Roijer, E.2    Imamura, T.3    Souchelnytskyi, S.4    Stenman, G.5    Heldin, C.H.6    Al, E.7
  • 7
    • 0030300115 scopus 로고    scopus 로고
    • MADR2 is a substrate of the TGFβ receptor and its phosphorylation is required for nuclear accumulation and signaling
    • Macias-Silva M, Abdollah S, Hoodless PA, Pirone R, Attisano L, Wrana JL (1996) MADR2 is a substrate of the TGFβ receptor and its phosphorylation is required for nuclear accumulation and signaling. Cell 87, 1215 1224.
    • (1996) Cell , vol.87 , pp. 1215-1224
    • MacIas-Silva, M.1    Abdollah, S.2    Hoodless, P.A.3    Pirone, R.4    Attisano, L.5    Wrana, J.L.6
  • 12
    • 0029874495 scopus 로고    scopus 로고
    • The role of MAP kinase kinase in Interleukin -3 stimulation of proliferation
    • Perkins GR, Marshall CJ, Collins MKL (1996) The role of MAP kinase kinase in Interleukin -3 stimulation of proliferation. Blood 87, 3669 3675.
    • (1996) Blood , vol.87 , pp. 3669-3675
    • Perkins, G.R.1    Marshall, C.J.2    Collins, M.K.L.3
  • 13
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • Marshall CJ (1995) Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80, 179 185.
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 14
    • 0026733002 scopus 로고
    • PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity
    • Qiu M, Green SH (1992) PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity. Neuron 9, 705 717.
    • (1992) Neuron , vol.9 , pp. 705-717
    • Qiu, M.1    Green, S.H.2
  • 15
    • 0034116561 scopus 로고    scopus 로고
    • Prolonged activation of the Mitogen-activated Protein Kinase pathway is required for macrophage-like differentiation of a Human Myeloid leukemic cell line
    • Hu X, Moscinski LC, Valkov NI, Fisher AB, Hill BJ, Zuckerman KS (2000) Prolonged activation of the Mitogen-activated Protein Kinase pathway is required for macrophage-like differentiation of a Human Myeloid leukemic cell line. Cell Growth Differ. 11, 191 200.
    • (2000) Cell Growth Differ. , vol.11 , pp. 191-200
    • Hu, X.1    Moscinski, L.C.2    Valkov, N.I.3    Fisher, A.B.4    Hill, B.J.5    Zuckerman, K.S.6
  • 16
    • 0025258898 scopus 로고
    • Interleukin 3 and granulocyte-macrophage colony stimulating factor mediate rapid phosphorylation and activation of cytosolic c-raf
    • Carroll MP, Clark-Iewis I, Rapp UR, May WS (1990) Interleukin 3 and granulocyte-macrophage colony stimulating factor mediate rapid phosphorylation and activation of cytosolic c-raf. J. Biol. Chem. 265, 19812 19817.
    • (1990) J. Biol. Chem. , vol.265 , pp. 19812-19817
    • Carroll, M.P.1    Clark-Iewis, I.2    Rapp, U.R.3    May, W.S.4
  • 17
    • 0026061602 scopus 로고
    • GMCSF and IL-3 induce rapid phosphorylation and activation of the proto-oncogene Raf-1 in a human factor-dependent myeloid cell line
    • Kanakura Y, Druker B, Wood K, Mamon H, Okuda K, Roberts T et al 1991) GMCSF and IL-3 induce rapid phosphorylation and activation of the proto-oncogene Raf-1 in a human factor-dependent myeloid cell line. Blood 77, 243 248.
    • (1991) Blood , vol.77 , pp. 243-248
    • Kanakura, Y.1    Druker, B.2    Wood, K.3    Mamon, H.4    Okuda, K.5    Roberts, T.6    Al, E.7
  • 18
    • 0026753999 scopus 로고
    • Granulocyte-macrophage colony-stimulating factor, interleukin-3, and steel factor induce rapid tyrosine phosphorylation of p42 and p44 MAP kinase
    • Okuda K, Sanghera JS, Pelech SL, Kanakura Y, Hallek M, Griffin JD et al 1992) Granulocyte-macrophage colony-stimulating factor, interleukin-3, and steel factor induce rapid tyrosine phosphorylation of p42 and p44 MAP kinase. Blood 79, 2880 2887.
    • (1992) Blood , vol.79 , pp. 2880-2887
    • Okuda, K.1    Sanghera, J.S.2    Pelech, S.L.3    Kanakura, Y.4    Hallek, M.5    Griffin, J.D.6    Al, E.7
  • 19
    • 0033605359 scopus 로고    scopus 로고
    • Granulocyte-macrophage colony-stimulating factor-activated signaling pathways in human neutrophils. Involvement of Jak2 in the stimulation of phosphatidylinositol 3-kinase
    • Al-shami A, Naccache PH (1999) Granulocyte-macrophage colony-stimulating factor-activated signaling pathways in human neutrophils. Involvement of Jak2 in the stimulation of phosphatidylinositol 3-kinase. J. Biol. Chem. 274, 5333 5338.
    • (1999) J. Biol. Chem. , vol.274 , pp. 5333-5338
    • Al-Shami, A.1    Naccache, P.H.2
  • 20
    • 26444561822 scopus 로고
    • PI3-kinase activation by GM-CSF in endothelium is upstream of Jak/Stat pathway: Role of αgMR
    • Dhar-Mascareno M, Pedraza A, Golde DW (1993) PI3-kinase activation by GM-CSF in endothelium is upstream of Jak/Stat pathway: role of αGMR. BBRC 337 (551-556 2005.
    • (1993) BBRC , vol.337 , pp. 551-556
    • Dhar-Mascareno, M.1    Pedraza, A.2    Golde, D.W.3
  • 21
    • 0032859366 scopus 로고    scopus 로고
    • Transforming growth factor-beta stimulates articular chondrocyte cell growth through p44/42 MAP kinase (ERK) activation
    • Yonekura A, Osaki M, Hirota Y, Tsukazaki T, Miyazaki Y, Matsumoto T et al 1999) Transforming growth factor-beta stimulates articular chondrocyte cell growth through p44/42 MAP kinase (ERK) activation. Endocr J. 46, 545 553.
    • (1999) Endocr J. , vol.46 , pp. 545-553
    • Yonekura, A.1    Osaki, M.2    Hirota, Y.3    Tsukazaki, T.4    Miyazaki, Y.5    Matsumoto, T.6    Al, E.7
  • 22
    • 0036614369 scopus 로고    scopus 로고
    • Role of MAP kinases and their cross-talk in TGF-beta1-induced apoptosis in FaO rat hepatoma cell line
    • Park HJ, Kim BC, Kim SJ, Choi KS (2002) Role of MAP kinases and their cross-talk in TGF-beta1-induced apoptosis in FaO rat hepatoma cell line. Hepatology 35, 1360 1371.
    • (2002) Hepatology , vol.35 , pp. 1360-1371
    • Park, H.J.1    Kim, B.C.2    Kim, S.J.3    Choi, K.S.4
  • 23
    • 0042704734 scopus 로고    scopus 로고
    • Cross-talk between ERK MAP kinase and Smad signaling pathways enhances TGF-beta-dependent responses in human mesangial cells
    • Hayashida T, Decaestecker M, Schnaper HW (2003) Cross-talk between ERK MAP kinase and Smad signaling pathways enhances TGF-beta-dependent responses in human mesangial cells. FASEB J. 17, 1576 1578.
    • (2003) FASEB J. , vol.17 , pp. 1576-1578
    • Hayashida, T.1    Decaestecker, M.2    Schnaper, H.W.3
  • 24
    • 33746038942 scopus 로고    scopus 로고
    • The synthetic triterpenoid CDDO-imidazolide induces monocytic differentiation by activating the Smad and ERK signaling pathways in HL60 leukemia cells
    • Ji Y, Lee HJ, Goodman C, Uskokovic M, Liby K, Sporn M et al 2006) The synthetic triterpenoid CDDO-imidazolide induces monocytic differentiation by activating the Smad and ERK signaling pathways in HL60 leukemia cells. Mol. Cancer Ther. 5, 1452 1458.
    • (2006) Mol. Cancer Ther. , vol.5 , pp. 1452-1458
    • Ji, Y.1    Lee, H.J.2    Goodman, C.3    Uskokovic, M.4    Liby, K.5    Sporn, M.6    Al, E.7
  • 25
    • 19544368435 scopus 로고    scopus 로고
    • Smad7 induces tumorigenicity by blocking TGF-β-induced growth inhibition and apoptosis
    • Halder SK, Beauchamp RD, Datta PK (2005) Smad7 induces tumorigenicity by blocking TGF-β-induced growth inhibition and apoptosis. Exp Cell Res. 307, 231 246.
    • (2005) Exp Cell Res. , vol.307 , pp. 231-246
    • Halder, S.K.1    Beauchamp, R.D.2    Datta, P.K.3
  • 26
    • 0035909510 scopus 로고    scopus 로고
    • Differential effects of transforming growth factor on the cell cycle regulatory molecules in human myeloid leukemia cells
    • Hu X, Zhang X, Zhong Q, Fisher AB, Bryington M, Zuckerman KS (2001) Differential effects of transforming growth factor on the cell cycle regulatory molecules in human myeloid leukemia cells. Oncogene 20, 6840 6850.
    • (2001) Oncogene , vol.20 , pp. 6840-6850
    • Hu, X.1    Zhang, X.2    Zhong, Q.3    Fisher, A.B.4    Bryington, M.5    Zuckerman, K.S.6
  • 27
    • 0024318485 scopus 로고
    • Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin
    • Kitamura T, Tange T, Terasawa T, Chiba S, Kuwaki T, Miyagawa K et al 1989) Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin. J. Cell Physiol. 140, 323 334.
    • (1989) J. Cell Physiol. , vol.140 , pp. 323-334
    • Kitamura, T.1    Tange, T.2    Terasawa, T.3    Chiba, S.4    Kuwaki, T.5    Miyagawa, K.6    Al, E.7
  • 28
    • 0032171605 scopus 로고    scopus 로고
    • Characterization of a unique factor-independent variant derived from human factor-dependent TF-1 cells: A transformed event
    • Hu X, Moscinski LC, Hill BJ, Fisher AB, Zuckerman KS (1998) Characterization of a unique factor-independent variant derived from human factor-dependent TF-1 cells: a transformed event. Leukemia Res. 22, 817 826.
    • (1998) Leukemia Res. , vol.22 , pp. 817-826
    • Hu, X.1    Moscinski, L.C.2    Hill, B.J.3    Fisher, A.B.4    Zuckerman, K.S.5
  • 29
    • 0023272413 scopus 로고
    • Growth factor requirements of childhood acute leukemia: Establishment of GM-CSF-dependent cell lines
    • Lange B, Valtieri M, Santoli D, Caracciolo D, Mavilio F, Gemperlein I et al 1987) Growth factor requirements of childhood acute leukemia: establishment of GM-CSF-dependent cell lines. Blood 70, 192 199.
    • (1987) Blood , vol.70 , pp. 192-199
    • Lange, B.1    Valtieri, M.2    Santoli, D.3    Caracciolo, D.4    Mavilio, F.5    Gemperlein, I.6    Al, E.7
  • 30
    • 0030614715 scopus 로고    scopus 로고
    • The subcellular locations of p15ink4b and p27kip1 coordinate their inhibitory interactions with Cdk4 and cdk2
    • Reynisdottir I, Massague J (1997) The subcellular locations of p15ink4b and p27kip1 coordinate their inhibitory interactions with Cdk4 and cdk2. Genes Dev 11, 492 503.
    • (1997) Genes Dev , vol.11 , pp. 492-503
    • Reynisdottir, I.1    Massague, J.2
  • 31
    • 15444372825 scopus 로고    scopus 로고
    • Type i transforming growth factor beta receptor binds to and activates phosphatidylinositol 3-kinase
    • Yi JY, Shin I, Arteaga CL (2005) Type I transforming growth factor beta receptor binds to and activates phosphatidylinositol 3-kinase. J. Biol. Chem. 280, 10870 10876.
    • (2005) J. Biol. Chem. , vol.280 , pp. 10870-10876
    • Yi, J.Y.1    Shin, I.2    Arteaga, C.L.3
  • 32
    • 0031000626 scopus 로고    scopus 로고
    • Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase
    • Whalen AM, Galasinski SG, Shapiro P, Nahreini TS, Ahn NG (1997) Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase. Mol Cell Biol. 17, 1947 1958.
    • (1997) Mol Cell Biol. , vol.17 , pp. 1947-1958
    • Whalen, A.M.1    Galasinski, S.G.2    Shapiro, P.3    Nahreini, T.S.4    Ahn, N.G.5
  • 33
    • 31044448265 scopus 로고    scopus 로고
    • Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-β1-induced extracellular matrix expression
    • Jinnin M, Ihn H, Tamaki K (2006) Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-β1-induced extracellular matrix expression. Mol. Pharmacol. 69, 597 607.
    • (2006) Mol. Pharmacol. , vol.69 , pp. 597-607
    • Jinnin, M.1    Ihn, H.2    Tamaki, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.