Clinical effectiveness of autologous platelet-rich plasma and peptide-enhanced bone graft in the treatment of intrabony defects

Journal of Periodontology

Volumn 80, Issue 1, 2009, Pages 62-71

  Pradeep, A R ^a   Shetty, Sharath Kumara ^a   Garg, Garima ^a   Pai, Sujatha ^a  

^a GOVERNMENT DENTAL COLLEGE AND RESEARCH INSTITUTE   (India)

Author keywords

Platelet rich plasma; Spiral CT

Indexed keywords

CELL BINDING PEPTIDE P 15; CELL-BINDING PEPTIDE P-15; COLLAGEN; PEPTIDE FRAGMENT;

ADULT; ARTICLE; AUTOTRANSPLANTATION; BONE MATRIX; BONE REGENERATION; BONE TRANSPLANTATION; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; FOLLOW UP; GINGIVA BLEEDING; GINGIVA DISEASE; HUMAN; IMAGE PROCESSING; JAW; MALE; METHODOLOGY; MIDDLE AGED; OSTEOLYSIS; PERIODONTAL DISEASE; PERIODONTICS; PERIODONTITIS; PHYSIOLOGY; RADIOGRAPHY; RANDOMIZED CONTROLLED TRIAL; SPIRAL COMPUTER ASSISTED TOMOGRAPHY; THREE DIMENSIONAL IMAGING; THROMBOCYTE RICH PLASMA; TOOTH PLAQUE; TRANSPLANTATION; TREATMENT OUTCOME;

ADULT; ALVEOLAR BONE LOSS; ALVEOLAR PROCESS; BONE MATRIX; BONE REGENERATION; BONE TRANSPLANTATION; COLLAGEN; DENTAL PLAQUE INDEX; FEMALE; FOLLOW-UP STUDIES; GINGIVAL HEMORRHAGE; GINGIVAL RECESSION; GUIDED TISSUE REGENERATION, PERIODONTAL; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; MALE; MIDDLE AGED; PEPTIDE FRAGMENTS; PERIODONTAL ATTACHMENT LOSS; PERIODONTAL POCKET; PLATELET-RICH PLASMA; TOMOGRAPHY, SPIRAL COMPUTED; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 58349120848     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2009.080214     Document Type: Article

References (46)

1. Yukna RA, Krauser JT, Callan DP, Evans GH, Cruz R, Martin M. Multi-center clinical comparison of combination anorganic bovine-derived hydroxyapatite matrix (ABM)/cell binding peptide (P-15) and ABM in human periodontal osseous defects. 6-month results. J Periodontol 2000;71:1671-1679.
2. Yukna RA, Salinas TJ, Carr RF. Periodontal regeneration following use of ABM/P-15: A case report. Int J Periodontics Restorative Dent 2002;22:146-155.
3. Bhongade ML, Tiwari IR. A comparative evaluation of the effectiveness of an anorganic bone matrix/cell binding peptide with an open flap debridement in human infrabony defects: A clinical and radiographic study. J Contemp Dent Pract 2007;8:25-34.
4. Yukna RA, Callan DP, Krauser JT, et al. Multi-center clinical evaluation of combination anorganic bovine-derived hydroxyapatite matrix (ABM)/cell binding peptide (P-15) as a bone replacement graft material in human periodontal osseous defects. 6-month results. J Periodontol 1998;69:655-663.
5. Kiritsy CP, Lynch AB, Lynch SE. Role of growth factors in cutaneous wound healing: A review. Crit Rev Oral Biol Med 1993;4:729-760.
6. Oates TW, Rouse CA, Cochran DL. Mitogenic effects of growth factors on human periodontal ligament cells in vitro. J Periodontol 1993;64:142-148.
7. Howell TH, Fiorellini JP, Paquette DW, Offenbacher S, Giannobile WV, Lynch SE. A phase I/II clinical trial to evaluate a combination of recombinant human-derived growth factor-BB and recombinant human insulin like growth factor-I in patients with periodontal disease. J Periodontol 1997;68:1186-1193.
8. Sporn MB, Roberts AB. Transforming growth factor-β: Recent progress and new challenges. J Cell Biol 1992;119:1017-1021.
9. Assoian RK, Grotendorst GR, Miller DM, Sporn MB. Cellular transformation by coordinated action of three peptide growth factors from human platelets. Nature 1984;309:804-806.
10. Marx RE, Carlson ER, Eichstaedt RM, Schimmele SR, Strauss JE, Georgeff KR. Platelet-rich plasma: Growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998;85:638-646.
11. Silness J, Löe H. Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 1964;22:121-135.
12. Miller SC. Textbook of Periodontia, 3rd ed. Philadelphia: Blackstone; 1950:125.
13. Mühlemann HR, Son S. Gingival sulcus bleeding - A leading symptom in initial gingivitis. Helv Odontol Acta 1971;15:107-113.
14. Su CY, Chiang CC, Lai WF, Lin KW, Burnouf T. Platelet-derived growth factor-AB and transforming growth factor-β1 in platelet gels activated by single-donor human thrombin. Transfusion 2004;44:945.
15. Jeffcoat MK, Wang IC, Reddy M. Radiographic diagnosis in periodontics. Periodontol 2000 1995;7:54-68.
16. Armitage GC. Periodontal diseases: Diagnosis. Ann Periodontol 1996;1:37-215.
17. Hausmann E, Allen K, Christersson L, Genco R. Effect of x-ray beam vertical angulation on radiographic alveolar crest level measurements. J Periodontal Res 1989;24:8-19.
18. Reddy M. Radiographic evaluation of periodontal therapy. J Periodontol 1992;63:1078-1084.
19. Fuhrmann RAW, Biicker A, Diedrich PR. Assessment of alveolar bone loss with high resolution computed tomography. J Periodontal Res 1995;30:258-263.
20. Naito T, Hosokawa R, Yokota M. Three-dimensional alveolar bone morphology analysis using computed tomography. J Periodontol 1998;69:584-589.
21. de Obarrio JJ, Araúz-Dutari JI, Chamberlain TM, Croston A. The use of autologous growth factors in periodontal surgical therapy: Platelet gel biotechnology - Case reports. Int J Periodontics Restorative Dent 2000;20:486-497.
22. Okuda K, Kawase T, Momose M, et al. Platelet-rich plasma contains high levels of platelet-derived growth factor and transforming growth factor-beta and modulates the proliferation of periodontally related cells in vitro. J Periodontol 2003;74:849-857.
23. Kawase T, Okuda K, Saito Y, Yoshie H. In vitro evidence that the biological effects of platelet-rich plasma on periodontal ligament cells is not mediated solely by constituent transforming-growth factor-beta or platelet-derived growth factor. J Periodontol 2005;76:760-767.
24. Camargo PM, Lekovic V, Weinlaender M, Vasilic N, Madzarevic M, Kenney EB. A reentry study on the use of bovine porous bone mineral, GTR, and platelet-rich plasma in the regenerative treatment of intrabony defects in humans. Int J Periodontics Restorative Dent 2005;25:49-59.
25. Polson AM, Proye MP. Fibrin linkage: A precursor for new attachment. J Periodontol 1983;54:141-147.
26. Wikesjo UME, Nilveus RE, Selvig KE. Significance of early healing events on periodontal repair. A review. J Periodontol 1992;63:158-165.
27. Gottlow J. Periodontal regeneration. In: Lang NP, Karring T, eds. Proceedings of the 1st European Workshop in Periodontology. London: Quintessence Publishing; 1994:172-192.
28. El-Sharkawy H, Kantarci A, Deady J, et al. Platelet-rich plasma: Growth factors and pro- and anti-inflammatory properties. J Periodontol 2007;78:661-669.
29. Dallari D, Fini M, Stagni C, et al. In vivo study on the healing of bone defects treated with bone marrow stromal cells, platelet-rich plasma and freeze-dried bone allografts, alone and in combination. J Orthop Res 2006;24:877-888.
30. Aghaloo TL, Moy PK, Freymiller EG. Evaluation of platelet-rich plasma in combination with freeze-dried bone in the rabbit cranium. A pilot study. Clin Oral Implants Res 2005;16:250-257.
31. Yamada Y, Ueda M, Naiki T, Takahashi M, Hata K, Nagasaka T. Autogenous injectable bone for regeneration with mesenchymal stem cells and platelet-rich plasma: Tissue-engineered bone regeneration. Tissue Eng 2004;10:955-964.
32. Anitua E. Plasma rich in growth factors: Preliminary results of use in the preparation of future sites for implants. Int J Oral Maxillofac Implants 1999;14:529-535.
33. Sammartino G, Tia M, Marenzi G, di Lauro AE, D'Agostino E, Claúdio PP. Use of autologous platelet-rich plasma (PRP) in periodontal defect treatment after extraction of impacted mandibular third molars. J Oral Maxillofac Surg 2005;63:766-770.
34. Simon D, Manuel S, Geetha V, Naik BR. Potential for osseous regeneration of platelet-rich plasma - A comparative study in mandibular third molar sockets. Indian J Dent Res 2004;15:133-136.
35. Whitman DH, Berry RL, Green DM. Platelet gel: An autologous alternative to fibrin glue with applications in oral and maxillofacial surgery. J Oral Maxillofac Surg 1997;55:1294-1299.
36. Landesberg R, Roy M, Glickman RS. Quantification of growth factor levels using a simplified method of platelet-rich plasma gel preparation. J Oral Maxillofac Surg 2000;58:297-300.
37. Sonnleitner D, Huemer P, Sullivan DY. A simplified technique for producing platelet-rich plasma and platelet concentrate for intraoral bone grafting techniques: A technical note. Int J Oral Maxillofac Implants 2000;15:879-882.
38. Kassolis JD, Rosen PS, Reynolds MA. Alveolar ridge and sinus augmentation utilizing platelet-rich plasma in combination with freeze-dried bone allograft: Case series. J Periodontol 2000;71:1654-1661.
39. Gonshor A. Technique for producing platelet-rich plasma and platelet concentrate: Background and process. Int J Periodontics Restorative Dent 2002;22:547-557.
40. Robiony M, Polini F, Costa F, Politi M. Osteogenesis distraction and platelet rich plasma for bone restoration of the severely atrophic mandible: Preliminary results. J Oral Maxillofac Surg 2002;60:630-635.
41. Banninger H, Hardegger T, Tobler A, et al. Fibrin glue in surgery: Frequent development of inhibitors of bovine thrombin and human factor V. Br J Haematol 1993;85:528-532.
42. Thorn JJ, Sorensen H, Weis-Fogh U, Andersen M. Autologous fibrin glue with growth factors in reconstructive maxillofacial surgery. Int J Oral Maxillofac Surg 2004;33:95-100.
43. Lekovic V, Camargo PM, Weinlenden M, Vasilic N, Kenney B. Comparison of platelet rich plasma, bovine porous bone mineral and guided tissue regeneration versus platelet rich plasma, bovine porous bone mineral in the treatment of intrabony defects: A reentry study. J Periodontol 2002;73:198-205.
44. Okuda K, Tai H, Tanabe K, et al. Platelet-rich plasma combined with a porous hydroxyapatite graft for the treatment of intrabony periodontal defects in humans: A comparative controlled clinical study. J Periodontol 2005;76:890-898.
45. Demir B, Sengün D, Berberoglu A. Clinical evaluation of platelet-rich plasma and bioactive glass in the treatment of intra-bony defects. J Clin Periodontol 2007;34:709-715.
46. Hanna R, Trejo PM, Weltman RL. Treatment of intrabony defects with bovine-derived xenograft alone and in combination with platelet-rich plasma: A randomized clinical trial. J Periodontol 2004;75:1668-1677.