Beyond airflow limitation: Another look at COPD

Thorax

Volumn 64, Issue 1, 2009, Pages 2-4

  Pistolesi, Massimo ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AIRFLOW; AIRWAY OBSTRUCTION; BODY MASS; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL PRACTICE; COUGHING; EDITORIAL; EMPHYSEMA; EXPIRATORY FLOW; FORCED EXPIRATORY VOLUME; GENETIC DIFFERENCE; HIGH RESOLUTION COMPUTER TOMOGRAPHY; LUNG FUNCTION; LUNG PARENCHYMA; MORBIDITY; MORTALITY; MULTIVARIATE ANALYSIS; NEUTROPHIL COUNT; PATHOLOGY; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; RADIATION ATTENUATION; SPIROMETRY; THORAX RADIOGRAPHY; UNIVARIATE ANALYSIS;

EID: 58349104979     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thx.2008.106674     Document Type: Editorial

References (27)

1. Burrows B, Fletcher CM, Heard BE, et al. The emphysematous and bronchial types of chronic airways obstruction. A clinicopathological study of patients in London and Chicago. Lancet 1966;87:830-5.
2. Ogawa E, Nakano Y, Ohara T, et al. Body mass index in male patients with COPD: correlation with low attenuation area on CT. Thorax 2009;64:20-25.
3. Kitaguchi Y, Fujimoto K, Kubo K, et al. Characteristics of COPD phenotypes classified according to the findings of HRCT. Respir Med 2006;100:1742-52.
4. Makita H, Nasuhara Y, Nagai K, et al. Characterisation of phenotypes based on severity of emphysema in chronic obstructive pulmonary disease. Thorax 2007;62:932-7.
5. Lee YK, Oh YM, Lee JH, et al. Quantitative assessment of emphysema, air trapping, and airway thickening on computed tomography. Lung 2008;186:157-65.
6. Pistolesi M, Camiciottoli G, Paoletti M et al. Identification of a predominant phenotype of COPD in clinical practice. Respir Med 2008;102:367-76.
7. Madani A, Zanen J, de Maertelaer V, et al. Pulmonary emphysema: objective quantification at multidetector row CT. Comparison with macroscopic and microscopic morphometry. Radiology 2006;238:1036- 43.
8. Nakano Y, Wong JC, de Jong PA, et al. The prediction of small airway dimensions using computed tomography. Am J Respir Crit Care Med 2005;171:142-6.
9. Gelb AF, Hogg JC, Müller NL, et al. Contribution of emphysema and small airways in COPD. Chest 1996;109:353-9.
10. Nishimura K, Izumi T, Tsukino M, et al. Dyspnea is a better predictor of 5-year survival than airway obstruction in patients with COPD. Chest 2002;121:1434-40.
11. Vestbo J, Anderson W, Coxson HO, et al. Evaluation of COPD longitudinally to identify predictive surrogate end-points (ECLIPSE). Eur Respir J 2008;31:869-73.
12. Wedzicha JA. The heterogeneity of chronic obstructive pulmonary disease. Thorax 2000;55:631-2.
13. Friedlander AL, Linch D, Dyar LA, et al. Phenotypes of chronic obstructive pulmonary disease. COPD: J Chronic Obstructive Pulm Dis 2007;4:355-84.
14. Vestbo J. COPD, diagrams and traditions: time to move on? Thorax 2008;63:755-6.
15. Rennard SI, Vestbo J. The many "Small COPDs": COPD should be an orphan disease. Chest 2008;134:623-7.
16. 1-time to divide and conquer. N Engl J Med 2008;359:1616-18.
17. de Marco R. What evidence could validate the definition of COPD? Thorax 2008;63:756-7.
18. Burge PS. Euroscop, Isolde, and the Copenhagen City Lung Study. Thorax 1999;54:287-8.
19. Calverley PM, Anderson JA, Celli B, et al. Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N Engl J Med 2007:22:356:775-89.
20. Tashkin DP, Celli B, Senn S, et al. A 4-year trial of tiotropium in chronic obstructive pulmonary disease. N Engl J Med 2008;359:1548-54.
21. Nakano Y, Muro S, Sakai H, et al. Computed tomographic measurements of airway dimensions and emphysema in smokers. Correlation with lung function. Am J Respir Crit Care Med 2000;162:1102-8.
22. Hogg JC, Macklem PT, Thurlbeck WM. Site and nature of airways obstruction in chronic obstructive lung disease. N Engl J Med 1968;278:1355-60.
23. Orlandi I, Moroni C, Camiciottoli G, et al. Chronic obstructive pulmonary disease: thin-section CT measurement of airway wall thickness and lung attenuation. Radiology 2005;234:604-10.
24. O'Donnell RA, Peebles C, Ward JA, et al. Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD. Thorax 2004;59:837-42.
25. Croxton TL, Weinman GG, Senior RM, et al. Clinical research in chronic obstructive pulmonary disease. Needs and opportunities. Am J Respir Crit Care Med 2003;167:1142-9.
26. Marsh SE, Travers J, Weatherall M, et al. Proportional classification of COPD phenotypes. Thorax 2008;63:761-7.
27. Hogg JC, Pierce RA. Remodelling of peripheral lung tissue in COPD. Eur Respir J 2008;31:913-14.