Congenital pseudarthrosis of neurofibromatosis type 1: Impaired osteoblast differentiation and function and altered NF1 gene expression

Bone

Volumn 44, Issue 2, 2009, Pages 243-250

  Leskelä, Hannu Ville ^a   Kuorilehto, Tommi ^a,b   Risteli, Juha ^a   Koivunen, Jussi ^a   Nissinen, Marja ^a   Peltonen, Sirkku ^c   Kinnunen, Pentti ^d   Messiaen, Ludwine ^e   Lehenkari, Petri ^a   Peltonen, Juha ^a,b,d  

^a UNIVERSITY OF OULU   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c TURKU UNIVERSITY HOSPITAL   (Finland)

^d OULU UNIVERSITY HOSPITAL   (Finland)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Collagen; Congenital pseudarthrosis of the tibia; Mesenchymal stem cell; Neurofibromatosis type 1; Neurofibromin; Osteoblast; Skeletal

Indexed keywords

MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A;

ALLELE; ARTICLE; BONE MARROW; CASE REPORT; CELL DIFFERENTIATION; CELL FUNCTION; CHILD; CONGENITAL PSEUDARTHROSIS; CONTROLLED STUDY; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; FEMALE; GENE; GENE EXPRESSION; GENE LOCATION; GENE MUTATION; GENETIC ANALYSIS; HETEROZYGOSITY; HUMAN; HUMAN TISSUE; ILIAC CREST; IMMUNOCYTOCHEMISTRY; MALE; MESENCHYMAL STEM CELL; NEUROFIBROMATOSIS; NF1 GENE; ORTHOPEDIC SURGERY; OSTEOBLAST; OSTEOCLAST; TIBIA;

BONE MARROW CELLS; CELL DIFFERENTIATION; CHILD; CHILD, PRESCHOOL; DNA MUTATIONAL ANALYSIS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MESENCHYMAL STEM CELLS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEUROFIBROMATOSIS 1; NEUROFIBROMIN 1; OSTEOBLASTS; PSEUDARTHROSIS; RNA, MESSENGER; TIBIA;

EID: 58249098814     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2008.10.050     Document Type: Article

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