메뉴 건너뛰기




Volumn 417, Issue 2, 2009, Pages 561-571

Functional analysis of rat liver citrate carrier promoter: Differential responsiveness to polyunsaturated fatty acids

Author keywords

Citrate carrier; Gene expression; Lipogenesis; Poly unsaturated fatty acids (PUFA); Rat liver; Sterol regulatory element binding protein 1 (SREBP 1)

Indexed keywords

CITRATE CARRIER; LIPOGENESIS; POLY-UNSATURATED FATTY ACIDS (PUFA); RAT LIVER; STEROL REGULATORY ELEMENT-BINDING PROTEIN-1 (SREBP-1);

EID: 58249093554     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20081082     Document Type: Article
Times cited : (27)

References (40)
  • 1
    • 1242317666 scopus 로고    scopus 로고
    • The mitochondrial transporter family (SLC25): Physiological and pathological implications
    • Palmieri, F. (2004) The mitochondrial transporter family (SLC25): physiological and pathological implications. Eur. J. Physiol. 447, 689-709
    • (2004) Eur. J. Physiol , vol.447 , pp. 689-709
    • Palmieri, F.1
  • 2
    • 0027142559 scopus 로고
    • Structure, function and regulation of the tricarboxylate transport protein from rat liver mitochondria
    • Kaplan, R. S. and Mayor, J. A. (1993) Structure, function and regulation of the tricarboxylate transport protein from rat liver mitochondria. J. Bioenerg. Biomembr. 25, 503-514
    • (1993) J. Bioenerg. Biomembr , vol.25 , pp. 503-514
    • Kaplan, R.S.1    Mayor, J.A.2
  • 4
    • 33745806177 scopus 로고    scopus 로고
    • Hypothyroidism reduces tricarboxylate carrier activity and expression in rat liver mitochondria by reducing nuclear transcription rate and splicing efficiency
    • Siculella, L., Sabetta, S., Giudetti, A. M. and Gnoni, G. V. (2006) Hypothyroidism reduces tricarboxylate carrier activity and expression in rat liver mitochondria by reducing nuclear transcription rate and splicing efficiency. J. Biol. Chem. 281, 19072-19080
    • (2006) J. Biol. Chem , vol.281 , pp. 19072-19080
    • Siculella, L.1    Sabetta, S.2    Giudetti, A.M.3    Gnoni, G.V.4
  • 5
    • 0344667490 scopus 로고    scopus 로고
    • Differential effects of coconut oil- and fish oil-enriched diets on tricarboxylate carrier in rat liver mitochondria
    • Giudetti, A. M., Sabetta, S., di Summa, R., Leo, M., Damiano, F., Siculella, L. and Gnoni, G. V. (2003) Differential effects of coconut oil- and fish oil-enriched diets on tricarboxylate carrier in rat liver mitochondria. J. Lipid Res. 44, 2135-2141
    • (2003) J. Lipid Res , vol.44 , pp. 2135-2141
    • Giudetti, A.M.1    Sabetta, S.2    di Summa, R.3    Leo, M.4    Damiano, F.5    Siculella, L.6    Gnoni, G.V.7
  • 6
    • 3042519207 scopus 로고    scopus 로고
    • n-6 PUFA down-regulate expression of the tricarboxylate carrier in rat liver by transcriptional and post-transcriptional mechanisms
    • Siculella, L., Damiano, F., Sabetta, S. and Gnoni, G. V. (2004) n-6 PUFA down-regulate expression of the tricarboxylate carrier in rat liver by transcriptional and post-transcriptional mechanisms. J. Lipid Res. 45, 1333-1340
    • (2004) J. Lipid Res , vol.45 , pp. 1333-1340
    • Siculella, L.1    Damiano, F.2    Sabetta, S.3    Gnoni, G.V.4
  • 7
    • 10044220811 scopus 로고    scopus 로고
    • Different dietary fatty acids have dissimilar effects on activity and gene expression of mitochondrial tricarboxylate carrier in rat liver
    • Siculella, L., Sabetta, S., Damiano, F., Giudetti, A. M. and Gnoni, G. V. (2004) Different dietary fatty acids have dissimilar effects on activity and gene expression of mitochondrial tricarboxylate carrier in rat liver. FEBS Lett. 578, 280-284
    • (2004) FEBS Lett , vol.578 , pp. 280-284
    • Siculella, L.1    Sabetta, S.2    Damiano, F.3    Giudetti, A.M.4    Gnoni, G.V.5
  • 8
    • 0028855519 scopus 로고
    • Physiological and molecular mechanisms involved in nutritional regulation of fatty acid synthesis
    • Hillgartner, F. B., Salati, L. M. and Goodridge, A. G. (1995) Physiological and molecular mechanisms involved in nutritional regulation of fatty acid synthesis. Physiol. Rev. 75, 47-76
    • (1995) Physiol. Rev , vol.75 , pp. 47-76
    • Hillgartner, F.B.1    Salati, L.M.2    Goodridge, A.G.3
  • 9
    • 23944435868 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid regulation of genes of lipid metabolism
    • Sampath, H. and Ntambi, J. M. (2005) Polyunsaturated fatty acid regulation of genes of lipid metabolism. Annu. Rev. Nutr. 25, 317-340
    • (2005) Annu. Rev. Nutr , vol.25 , pp. 317-340
    • Sampath, H.1    Ntambi, J.M.2
  • 10
    • 0029797604 scopus 로고    scopus 로고
    • Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a
    • Shimano, H., Horton, J. D., Hammer, R. E., Shimomura, I., Brown, M. S. and Goldstein, J. L. (1996) Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. J. Clin. Invest. 98, 1575-1584
    • (1996) J. Clin. Invest , vol.98 , pp. 1575-1584
    • Shimano, H.1    Horton, J.D.2    Hammer, R.E.3    Shimomura, I.4    Brown, M.S.5    Goldstein, J.L.6
  • 12
    • 0030604717 scopus 로고    scopus 로고
    • Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment
    • Sakai, J., Duncan, E. A., Rawson, R. B., Hua, X., Brown, M. S. and Goldstein, J. L. (1996) Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment. Cell 85, 1037-1046
    • (1996) Cell , vol.85 , pp. 1037-1046
    • Sakai, J.1    Duncan, E.A.2    Rawson, R.B.3    Hua, X.4    Brown, M.S.5    Goldstein, J.L.6
  • 13
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • Brown, M. S. and Goldstein, J. L. (1997) The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89, 331-340
    • (1997) Cell , vol.89 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 14
    • 0033613147 scopus 로고    scopus 로고
    • A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood
    • Brown, M. S. and Goldstein, J. L. (1999) A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood. Proc. Natl. Acad. Sci. U.S.A. 96, 11041-11048
    • (1999) Proc. Natl. Acad. Sci. U.S.A , vol.96 , pp. 11041-11048
    • Brown, M.S.1    Goldstein, J.L.2
  • 15
    • 0027167918 scopus 로고
    • Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. II. Purification and characterization
    • Wang, X., Briggs, M. R., Hua, X., Yokoyama, C., Goldstein, J. L. and Brown, M. S. (1993) Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. II. Purification and characterization. J. Biol. Chem. 268, 14497-14504
    • (1993) J. Biol. Chem , vol.268 , pp. 14497-14504
    • Wang, X.1    Briggs, M.R.2    Hua, X.3    Yokoyama, C.4    Goldstein, J.L.5    Brown, M.S.6
  • 16
    • 0028963743 scopus 로고
    • Dual DNA binding specificity of ADD1/SREBP1 controlled by a single amino acid in the basic helix-loop-helix domain
    • Kim, J. B., Spotts, G. D., Halvorsen, Y. D., Shih, H. M., Ellenberger, T., Towle, H. C. and Spiegelman, B. M. (1995) Dual DNA binding specificity of ADD1/SREBP1 controlled by a single amino acid in the basic helix-loop-helix domain. Mol. Cell. Biol. 15, 2582-2588
    • (1995) Mol. Cell. Biol , vol.15 , pp. 2582-2588
    • Kim, J.B.1    Spotts, G.D.2    Halvorsen, Y.D.3    Shih, H.M.4    Ellenberger, T.5    Towle, H.C.6    Spiegelman, B.M.7
  • 17
    • 0032475841 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids decrease expression of promoters with sterol regulatory elements by decreasing levels of mature sterol regulatory element-binding protein
    • Worgall, T. S., Sturley, S. L., Seo, T., Osborne, T. F. and Deckelbaum, R. J. (1998) Polyunsaturated fatty acids decrease expression of promoters with sterol regulatory elements by decreasing levels of mature sterol regulatory element-binding protein. J. Biol. Chem. 273, 25537-25540
    • (1998) J. Biol. Chem , vol.273 , pp. 25537-25540
    • Worgall, T.S.1    Sturley, S.L.2    Seo, T.3    Osborne, T.F.4    Deckelbaum, R.J.5
  • 18
    • 0032730324 scopus 로고    scopus 로고
    • Sterol response element-binding protein 1c (SREBP1c) is involved in the polyunsaturated fatty acid suppression of hepatic S14 gene transcription
    • Mater, M. K., Thelen, A. P., Pan, D. A. and Jump, D. B. (1999) Sterol response element-binding protein 1c (SREBP1c) is involved in the polyunsaturated fatty acid suppression of hepatic S14 gene transcription. J. Biol. Chem. 274, 32725-32732
    • (1999) J. Biol. Chem , vol.274 , pp. 32725-32732
    • Mater, M.K.1    Thelen, A.P.2    Pan, D.A.3    Jump, D.B.4
  • 19
    • 43249114663 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acid regulation of hepatic gene transcription
    • Jump, D. B. (2008) N-3 polyunsaturated fatty acid regulation of hepatic gene transcription. Curr. Opin. Lipidol. 19, 242-247
    • (2008) Curr. Opin. Lipidol , vol.19 , pp. 242-247
    • Jump, D.B.1
  • 20
    • 0035830840 scopus 로고    scopus 로고
    • Unsaturated fatty acids down-regulate SREBP isoforms 1a and 1c by two mechanisms in HEK-293 cells
    • Hannah, V. C., Ou, J., Luong, A., Goldstein, J. L. and Brown, M. S. (2001) Unsaturated fatty acids down-regulate SREBP isoforms 1a and 1c by two mechanisms in HEK-293 cells. J. Biol. Chem. 276, 4365-4372
    • (2001) J. Biol. Chem , vol.276 , pp. 4365-4372
    • Hannah, V.C.1    Ou, J.2    Luong, A.3    Goldstein, J.L.4    Brown, M.S.5
  • 21
    • 33751117989 scopus 로고    scopus 로고
    • Insulin activates human sterol-regulatory-element-binding protein-1c (SREBP-1c) promoter through SRE motifs
    • Dif, N., Euthine, V., Gonnet, E., Laville, M., Vidal, H. and Lefai, E. (2006) Insulin activates human sterol-regulatory-element-binding protein-1c (SREBP-1c) promoter through SRE motifs. Biochem. J. 400, 179-188
    • (2006) Biochem. J , vol.400 , pp. 179-188
    • Dif, N.1    Euthine, V.2    Gonnet, E.3    Laville, M.4    Vidal, H.5    Lefai, E.6
  • 22
    • 0037200066 scopus 로고    scopus 로고
    • Insulin inhibits hepatocellular glucose production by utilizing liver-enriched transcriptional inhibitory protein to disrupt the association of CREB-binding protein and RNA polymerase II with the phosphoenolpyruvate carboxykinase gene promoter
    • Duong, D. T., Waltner-Law, M. E., Sears, R., Sealy, L. and Granner, D. K. (2002) Insulin inhibits hepatocellular glucose production by utilizing liver-enriched transcriptional inhibitory protein to disrupt the association of CREB-binding protein and RNA polymerase II with the phosphoenolpyruvate carboxykinase gene promoter. J. Biol. Chem. 277, 32234-32242
    • (2002) J. Biol. Chem , vol.277 , pp. 32234-32242
    • Duong, D.T.1    Waltner-Law, M.E.2    Sears, R.3    Sealy, L.4    Granner, D.K.5
  • 23
    • 33947261702 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid suppression of fatty acid synthase (FASN): Evidence for dietary modulation of NF-Y binding to the Fasn promoter by SREBP-1c
    • Teran-Garcia, M., Adamson, A. W., Yu, G., Rufo, C., Suchankova, G., Dreesen, T. D., Tekle, M., Clarke, S. D. and Gettys, T. W. (2007) Polyunsaturated fatty acid suppression of fatty acid synthase (FASN): evidence for dietary modulation of NF-Y binding to the Fasn promoter by SREBP-1c. Biochem. J. 402, 591-600
    • (2007) Biochem. J , vol.402 , pp. 591-600
    • Teran-Garcia, M.1    Adamson, A.W.2    Yu, G.3    Rufo, C.4    Suchankova, G.5    Dreesen, T.D.6    Tekle, M.7    Clarke, S.D.8    Gettys, T.W.9
  • 24
    • 12944259150 scopus 로고    scopus 로고
    • Nutritional regulation of the fatty acid synthase promoter in vivo: Sterol regulatory element binding protein functions through an upstream region containing a sterol regulatory element
    • Latasa, M. J., Moon, Y. S., Kim, K. H. and Sul, H. S. (2000) Nutritional regulation of the fatty acid synthase promoter in vivo: sterol regulatory element binding protein functions through an upstream region containing a sterol regulatory element. Proc. Natl. Acad. Sci. U.S.A. 97, 10619-10624
    • (2000) Proc. Natl. Acad. Sci. U.S.A , vol.97 , pp. 10619-10624
    • Latasa, M.J.1    Moon, Y.S.2    Kim, K.H.3    Sul, H.S.4
  • 26
    • 0023007801 scopus 로고
    • Purification and biochemical characterization of the promoter-specific transcription factor, Sp1
    • Briggs, M. R., Kadonaga, J. T., Bell, S. P. and Tjian, R. (1986) Purification and biochemical characterization of the promoter-specific transcription factor, Sp1. Science 234, 47-52
    • (1986) Science , vol.234 , pp. 47-52
    • Briggs, M.R.1    Kadonaga, J.T.2    Bell, S.P.3    Tjian, R.4
  • 28
    • 0036245227 scopus 로고    scopus 로고
    • Suppression of fatty acid synthase promoter by polyunsaturated fatty acids
    • Moon, Y. S., Latasa, M. J., Griffin, M. J. and Sul, H. S. (2002) Suppression of fatty acid synthase promoter by polyunsaturated fatty acids. J. Lipid Res. 43, 691-698
    • (2002) J. Lipid Res , vol.43 , pp. 691-698
    • Moon, Y.S.1    Latasa, M.J.2    Griffin, M.J.3    Sul, H.S.4
  • 29
    • 0021058853 scopus 로고
    • The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter
    • Dynan, W. S. and Tjian, R. (1983) The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter. Cell 35, 79-87
    • (1983) Cell , vol.35 , pp. 79-87
    • Dynan, W.S.1    Tjian, R.2
  • 31
    • 0021364584 scopus 로고
    • Structure, expression, and mutation of the hypoxanthine phosphoribosyltransferase gene
    • Melton, D. W., Konecki, D. S., Brennand, J. and Caskey, C. T. (1984) Structure, expression, and mutation of the hypoxanthine phosphoribosyltransferase gene. Proc. Natl. Acad. Sci U.S.A. 81, 2147-2151
    • (1984) Proc. Natl. Acad. Sci U.S.A , vol.81 , pp. 2147-2151
    • Melton, D.W.1    Konecki, D.S.2    Brennand, J.3    Caskey, C.T.4
  • 33
    • 33947137643 scopus 로고    scopus 로고
    • Transcription of the mitochondrial citrate carrier gene: Role of SREBP-1, upregulation by insulin and downregulation by PUFA
    • Infantino, V., Iacobazzi, V., De Santis, F., Mastrapasqua, M. and Palmieri, F. (2007) Transcription of the mitochondrial citrate carrier gene: role of SREBP-1, upregulation by insulin and downregulation by PUFA. Biochem. Biophys. Res. Commun. 356, 249-254
    • (2007) Biochem. Biophys. Res. Commun , vol.356 , pp. 249-254
    • Infantino, V.1    Iacobazzi, V.2    De Santis, F.3    Mastrapasqua, M.4    Palmieri, F.5
  • 34
    • 0036039741 scopus 로고    scopus 로고
    • The E-box like sterol regulatory element mediates the suppression of human Delta-6 desaturase gene by highly unsaturated fatty acids
    • Nara, T. Y., He, W. S., Tang, C., Clarke, S. D. and Nakamura, M. T. (2002) The E-box like sterol regulatory element mediates the suppression of human Delta-6 desaturase gene by highly unsaturated fatty acids. Biochem. Biophys. Res. Commun. 296, 111-117
    • (2002) Biochem. Biophys. Res. Commun , vol.296 , pp. 111-117
    • Nara, T.Y.1    He, W.S.2    Tang, C.3    Clarke, S.D.4    Nakamura, M.T.5
  • 35
    • 0040799893 scopus 로고    scopus 로고
    • Identification of conserved cis-elements and transcription factors required for sterol-regulated transcription of stearoyl-CoA desaturase 1 and 2
    • Tabor, D. E., Kim, J. B., Spiegelman, B. M. and Edwards, P. A. (1999) Identification of conserved cis-elements and transcription factors required for sterol-regulated transcription of stearoyl-CoA desaturase 1 and 2. J. Biol. Chem. 274, 20603-20610
    • (1999) J. Biol. Chem , vol.274 , pp. 20603-20610
    • Tabor, D.E.1    Kim, J.B.2    Spiegelman, B.M.3    Edwards, P.A.4
  • 36
    • 0034730504 scopus 로고    scopus 로고
    • The roles of sterol regulatory element-binding proteins in the transactivation of the rat ATP citrate-lyase promoter
    • Moon, Y. A., Lee, J. J., Park, S. W., Ahn, Y. H. and Kim, K. S. (2000) The roles of sterol regulatory element-binding proteins in the transactivation of the rat ATP citrate-lyase promoter. J. Biol. Chem. 275, 30280-30286
    • (2000) J. Biol. Chem , vol.275 , pp. 30280-30286
    • Moon, Y.A.1    Lee, J.J.2    Park, S.W.3    Ahn, Y.H.4    Kim, K.S.5
  • 37
    • 0036291404 scopus 로고    scopus 로고
    • NF-Y involvement in the polyunsaturated fat inhibition of fatty acid synthase gene transcription
    • Teran-Garcia, M., Rufo, C., Nakamura, M. T., Osborne, T. F. and Clarke, S. D. (2002) NF-Y involvement in the polyunsaturated fat inhibition of fatty acid synthase gene transcription. Biochem. Biophys. Res. Commun. 290, 1295-1299
    • (2002) Biochem. Biophys. Res. Commun , vol.290 , pp. 1295-1299
    • Teran-Garcia, M.1    Rufo, C.2    Nakamura, M.T.3    Osborne, T.F.4    Clarke, S.D.5
  • 38
    • 0039842456 scopus 로고    scopus 로고
    • Different sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase
    • Magaña, M. M., Koo, S. H., Towle, H. C. and Osborne, T. F. (2000) Different sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase. J. Biol. Chem. 275, 4726-4733
    • (2000) J. Biol. Chem , vol.275 , pp. 4726-4733
    • Magaña, M.M.1    Koo, S.H.2    Towle, H.C.3    Osborne, T.F.4
  • 39
    • 0034636014 scopus 로고    scopus 로고
    • Different sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase
    • Xiong, S., Chirala, S. S. and Wakil, S. J. (2000) Different sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase. Proc. Natl. Acad. Sci. U.S.A. 97, 3948-3953
    • (2000) Proc. Natl. Acad. Sci. U.S.A , vol.97 , pp. 3948-3953
    • Xiong, S.1    Chirala, S.S.2    Wakil, S.J.3
  • 40
    • 33745128696 scopus 로고    scopus 로고
    • How dietary arachidonic- and docosahexaenoic-acid rich oils differentially affect the murine hepatic transcriptome
    • Berger, A., Roberts, M. A. and Hoff, B. (2006) How dietary arachidonic- and docosahexaenoic-acid rich oils differentially affect the murine hepatic transcriptome. Lipids Health Dis. 5, 10
    • (2006) Lipids Health Dis , vol.5 , pp. 10
    • Berger, A.1    Roberts, M.A.2    Hoff, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.