-
1
-
-
0024564718
-
The new mouse genetics: Altering the genome by gene targeting
-
Capecchi, M. R. (1989) The new mouse genetics: altering the genome by gene targeting. Trends Genet. 5, 70-76.
-
(1989)
Trends Genet
, vol.5
, pp. 70-76
-
-
Capecchi, M.R.1
-
2
-
-
0026770668
-
High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors
-
Thomas, K. R., Deng, C., and Capecchi, M. R. (1992) High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors. Mol. Cell. Biol. 12, 2919-2923.
-
(1992)
Mol. Cell. Biol
, vol.12
, pp. 2919-2923
-
-
Thomas, K.R.1
Deng, C.2
Capecchi, M.R.3
-
3
-
-
0028468570
-
The P1 cloning system: Past and future
-
Sternberg, N. (1994) The P1 cloning system: past and future. Mamm. Genome 5, 397-404.
-
(1994)
Mamm. Genome
, vol.5
, pp. 397-404
-
-
Sternberg, N.1
-
4
-
-
0022669622
-
The integrase family of site-specific recombinases: Regional similarities and global diversity
-
Argos, P., Landy, A., Abremsky, K., Egan, J. B., Haggard-Ljungquist, E., Hoess, R. H., et al. (1986) The integrase family of site-specific recombinases: regional similarities and global diversity. EMBO J. 5, 433-440.
-
(1986)
EMBO J
, vol.5
, pp. 433-440
-
-
Argos, P.1
Landy, A.2
Abremsky, K.3
Egan, J.B.4
Haggard-Ljungquist, E.5
Hoess, R.H.6
-
5
-
-
0024041732
-
Site-specific DNA recombination in mamalian cells by the Cre recombinase of bacteriophage P1
-
Sauer, B. and Henderson, N. (1988) Site-specific DNA recombination in mamalian cells by the Cre recombinase of bacteriophage P1. Proc. Natl. Acad. Sci. USA 85, 5166-5170.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 5166-5170
-
-
Sauer, B.1
Henderson, N.2
-
6
-
-
0022419150
-
Mechanism of strand cleavage and exchange in the Cre-lox site-specific recombination system
-
Hoess, R. H. snd Abremski, K. (1985) Mechanism of strand cleavage and exchange in the Cre-lox site-specific recombination system. J. Mol. Biol. 181, 351-362.
-
(1985)
J. Mol. Biol
, vol.181
, pp. 351-362
-
-
Hoess, R.H.1
snd Abremski, K.2
-
7
-
-
0022355093
-
The FLP protein of the 2-micron plasmid of yeast. Purification of the protein from Escherichia coli cells expressing the cloned FLP gene
-
Babineau, D., Vetter, D., Andrews, B. J., Gronostajski, R. M., Proteau, G. A., Beatty, L. G., et al. (1985) The FLP protein of the 2-micron plasmid of yeast. Purification of the protein from Escherichia coli cells expressing the cloned FLP gene. J. Biol. Chem. 260, 12,313-12,319.
-
(1985)
J. Biol. Chem
, vol.260
-
-
Babineau, D.1
Vetter, D.2
Andrews, B.J.3
Gronostajski, R.M.4
Proteau, G.A.5
Beatty, L.G.6
-
8
-
-
0010986686
-
-
Kucherlapati, R. and Smith, G. R, eds, American Society for Microbiology, Washington DC, pp
-
Cox, M. M. (1988) in Genetic Recombination (Kucherlapati, R. and Smith, G. R., eds.), American Society for Microbiology, Washington DC, pp. 429-443.
-
(1988)
Genetic Recombination
, pp. 429-443
-
-
Cox, M.M.1
-
9
-
-
0025847620
-
Recombinase-mediated gene activation and site-specific integration in mammalian cells
-
O'Gorman, S., Fox, D. T., and Wahl, G. M. (1991) Recombinase-mediated gene activation and site-specific integration in mammalian cells. Science 251, 1351-1355.
-
(1991)
Science
, vol.251
, pp. 1351-1355
-
-
O'Gorman, S.1
Fox, D.T.2
Wahl, G.M.3
-
10
-
-
0027305095
-
An "in-out" strategy using gene targeting and FLP recombinase for the functional dissection of complex DNA regulatory elements: Analysis of the b-globin locus control region
-
Fiering, S., Kim, C. G., Epner, E. M., and Groudine, M. (1993) An "in-out" strategy using gene targeting and FLP recombinase for the functional dissection of complex DNA regulatory elements: analysis of the b-globin locus control region. Proc. Natl. Acad. Sci. USA 90, 8469-8473.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8469-8473
-
-
Fiering, S.1
Kim, C.G.2
Epner, E.M.3
Groudine, M.4
-
11
-
-
0029860719
-
Different thrermostabilities of FLP and Cre recombinases: Implications for applied site-specific recombination
-
Buchholz, F., Ringrose, L., Angrand, P.O., Rossi, F. and Stewart, A.F. (1996) Different thrermostabilities of FLP and Cre recombinases: implications for applied site-specific recombination. Nucleic Acids Res. 24, 4256-4262.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 4256-4262
-
-
Buchholz, F.1
Ringrose, L.2
Angrand, P.O.3
Rossi, F.4
Stewart, A.F.5
-
12
-
-
0029316784
-
Genome engineering: The new mouse genetics
-
Rossant, J. and Nagy, A. (1995) Genome engineering: the new mouse genetics. Nat. Med. 1, 592-594.
-
(1995)
Nat. Med
, vol.1
, pp. 592-594
-
-
Rossant, J.1
Nagy, A.2
-
13
-
-
60349086853
-
-
Lonai, P, ed, Harwood Academic Publishers, Amsterdam, pp
-
Nagy, A. (1996) in Mammalian Development (Lonai, P., ed.), Harwood Academic Publishers, Amsterdam, pp. 339-371.
-
(1996)
Mammalian Development
, pp. 339-371
-
-
Nagy, A.1
-
14
-
-
0032554783
-
-
Nagy, A., Moens, C., Ivanyi, E., Pawling, J. Gertsenstein, M,. Hadjantonakis, K., Pirity, M., and Rossant, J. (!998) Dissecting the role of N-myc in development using a single targeting vector to generate a series of alleles. Curr. Biol. 82, 661-664.
-
Nagy, A., Moens, C., Ivanyi, E., Pawling, J. Gertsenstein, M,. Hadjantonakis, K., Pirity, M., and Rossant, J. (!998) Dissecting the role of N-myc in development using a single targeting vector to generate a series of alleles. Curr. Biol. 82, 661-664.
-
-
-
-
15
-
-
0027280936
-
Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting
-
Gu, H., Zou, Y. R., and Rajewsky, K. (1993) Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting. Cell 73, 1155-1164.
-
(1993)
Cell
, vol.73
, pp. 1155-1164
-
-
Gu, H.1
Zou, Y.R.2
Rajewsky, K.3
-
16
-
-
0028950996
-
A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination
-
Smith, A. J. H., Sousa, M. A. D., Kwabi-Addo, B., Heppell-Parton, A., Impey, H., and Rabbitts, P. (1995) A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination. Nature Genetics 9, 376-385.
-
(1995)
Nature Genetics
, vol.9
, pp. 376-385
-
-
Smith, A.J.H.1
Sousa, M.A.D.2
Kwabi-Addo, B.3
Heppell-Parton, A.4
Impey, H.5
Rabbitts, P.6
-
17
-
-
0029562967
-
Chromosome engineering in mice
-
Ramirez-Solis, R., Liu, P., and Bradley, A. (1995) Chromosome engineering in mice. Nature 378, 720-724.
-
(1995)
Nature
, vol.378
, pp. 720-724
-
-
Ramirez-Solis, R.1
Liu, P.2
Bradley, A.3
-
18
-
-
0027321548
-
Derivation of completely cell culture-derived mice from early-passage embryonic stem cells
-
Nagy, A., Rossant, J., Nagy, R., Abramow-Newerly, W., and Roder, J. (1993) Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc. Natl. Acad. Sci. USA 90, 8424-8428.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8424-8428
-
-
Nagy, A.1
Rossant, J.2
Nagy, R.3
Abramow-Newerly, W.4
Roder, J.5
-
19
-
-
0029993528
-
Targeted mutagenesis: Analysis of phenotype without germ line transmission
-
Nagy, A. and Rossant, J. (1996) Targeted mutagenesis: Analysis of phenotype without germ line transmission. J. Clin. Invest. 97, 1360-1365.
-
(1996)
J. Clin. Invest
, vol.97
, pp. 1360-1365
-
-
Nagy, A.1
Rossant, J.2
-
20
-
-
0343920277
-
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
-
Carmeliet, P., Ferreira, V., Breier, G., Pollefeyt, S., Kieckens, L., Gertsenstein, M., et al. (1996) Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380, 435-439.
-
(1996)
Nature
, vol.380
, pp. 435-439
-
-
Carmeliet, P.1
Ferreira, V.2
Breier, G.3
Pollefeyt, S.4
Kieckens, L.5
Gertsenstein, M.6
-
21
-
-
0029850112
-
Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development
-
Zhang, H. & Bradley, A. (1996) Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development. Development 122, 2977-2986.
-
(1996)
Development
, vol.122
, pp. 2977-2986
-
-
Zhang, H.1
Bradley, A.2
-
22
-
-
60349100287
-
T cell-specific disruption of Pig-a gene involved in glycosylphosphatidylinositol (GPI) biosynthesis: Generation and function of T cells deficient in GPI-anchored proteins
-
in press
-
Takahama, Y., Ohishi, K., Tokoro, K., Sugawara, T., Yoshimura, Y., Okabe, M., et al. (1997) T cell-specific disruption of Pig-a gene involved in glycosylphosphatidylinositol (GPI) biosynthesis: Generation and function of T cells deficient in GPI-anchored proteins. Proc. Natl. Acad. Sci. USA, in press.
-
(1997)
Proc. Natl. Acad. Sci. USA
-
-
Takahama, Y.1
Ohishi, K.2
Tokoro, K.3
Sugawara, T.4
Yoshimura, Y.5
Okabe, M.6
-
23
-
-
0030460425
-
Subregion- and cell type-restricted gene knockout in mouse brain
-
Tsien, J. Z., Chen, D. F., Gerber, D., Tom, C., Mercer, E. H., Anderson, D. J., et al. (1996) Subregion- and cell type-restricted gene knockout in mouse brain. Cell 87, 1317-1326.
-
(1996)
Cell
, vol.87
, pp. 1317-1326
-
-
Tsien, J.Z.1
Chen, D.F.2
Gerber, D.3
Tom, C.4
Mercer, E.H.5
Anderson, D.J.6
-
24
-
-
0026526179
-
Temperature-dependent regulation of heterologous transcriptional activation domain fused to yeast heat shock transcription factor
-
Bonner, J. J., Heyward, S., and Fackenthal, D. L. (1992) Temperature-dependent regulation of heterologous transcriptional activation domain fused to yeast heat shock transcription factor. Mol. Cell. Biol. 12, 1021-1030.
-
(1992)
Mol. Cell. Biol
, vol.12
, pp. 1021-1030
-
-
Bonner, J.J.1
Heyward, S.2
Fackenthal, D.L.3
-
25
-
-
0021075353
-
Metallothionein-human GH fusion genes stimulate growth of mice
-
Palmiter, R. D., Norstedt, G., Gelinas, R. E., Hammer, R. E., and Brinster, R. L. (1983) Metallothionein-human GH fusion genes stimulate growth of mice. Science 222, 809-814.
-
(1983)
Science
, vol.222
, pp. 809-814
-
-
Palmiter, R.D.1
Norstedt, G.2
Gelinas, R.E.3
Hammer, R.E.4
Brinster, R.L.5
-
26
-
-
0029865151
-
Ecdysone-inducible gene expression in mammalian cells and transgenic mouse
-
No, D., Yao, T. P., and Evans, R. M. (1996) Ecdysone-inducible gene expression in mammalian cells and transgenic mouse. Proc. Natl. Acad. Sci. USA 93, 3346-3351.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 3346-3351
-
-
No, D.1
Yao, T.P.2
Evans, R.M.3
-
27
-
-
0026772125
-
Ecdysteroid-dependent regulation of genes in mammalian cells by a Drosophila ecdysone receptor and chimeric transactivators
-
Christopherson, K. S., Mark, M. R., Bajaj, V., and Godowski, P. J. (1992) Ecdysteroid-dependent regulation of genes in mammalian cells by a Drosophila ecdysone receptor and chimeric transactivators. Proc. Natl. Acad. Sci. USA 89, 6314-6318.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 6314-6318
-
-
Christopherson, K.S.1
Mark, M.R.2
Bajaj, V.3
Godowski, P.J.4
-
28
-
-
0026720075
-
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
-
Gossen, M. and Bujard, H. (1992) Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. USA 89, 5547-5551.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 5547-5551
-
-
Gossen, M.1
Bujard, H.2
-
29
-
-
9544226448
-
A humanized system for pharmacologic control of gene expression
-
Rivera, V. M., Clackson, T., Natesan, S., Pollock, R., Amara, J., Keenan, T., et al. (1996) A humanized system for pharmacologic control of gene expression. Nat. Med. 2, 1028-1032.
-
(1996)
Nat. Med
, vol.2
, pp. 1028-1032
-
-
Rivera, V.M.1
Clackson, T.2
Natesan, S.3
Pollock, R.4
Amara, J.5
Keenan, T.6
-
30
-
-
0023627388
-
Cell fate, morphogenetic movement and population kinetics of embryonic endoderm at the time of germ layer formation in the mouse
-
Lawson, K. A. and Pedersen, R. A. (1987) Cell fate, morphogenetic movement and population kinetics of embryonic endoderm at the time of germ layer formation in the mouse. Development 101, 627-652.
-
(1987)
Development
, vol.101
, pp. 627-652
-
-
Lawson, K.A.1
Pedersen, R.A.2
-
31
-
-
0028090122
-
Prospective fate map of the mouse primitive streak at 7.5 days of gestation
-
Smith, J. L., Gesteland, K. M., and Schoenwolf, G. C. (1994) Prospective fate map of the mouse primitive streak at 7.5 days of gestation. Dev. Dyn. 201, 279-289.
-
(1994)
Dev. Dyn
, vol.201
, pp. 279-289
-
-
Smith, J.L.1
Gesteland, K.M.2
Schoenwolf, G.C.3
-
32
-
-
0024542052
-
Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes
-
Gossler, A., Joyner, A. L., Rossant, J., and Skarnes, W. C. (1989) Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes. Science 244, 463-465.
-
(1989)
Science
, vol.244
, pp. 463-465
-
-
Gossler, A.1
Joyner, A.L.2
Rossant, J.3
Skarnes, W.C.4
-
33
-
-
0026493364
-
-
Joyner, A. L., Auerbach, A., and Scarnes.W.C. (1992) The gene trap approach in embryonic stem cells: the potential for genetic screens in mice. Ciba Foundation Symp. 165, 277-288.
-
Joyner, A. L., Auerbach, A., and Scarnes.W.C. (1992) The gene trap approach in embryonic stem cells: the potential for genetic screens in mice. Ciba Foundation Symp. 165, 277-288.
-
-
-
-
34
-
-
0029926149
-
An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro
-
Forrester, L. M., Nagy, A., Sam, M., Watt, A., Stevenson, L., Bernstein, A., et al. (1996) An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro. Proc. Natl. Acad. Sci. USA 93, 1677-1682.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 1677-1682
-
-
Forrester, L.M.1
Nagy, A.2
Sam, M.3
Watt, A.4
Stevenson, L.5
Bernstein, A.6
-
35
-
-
0024509412
-
Cre-stimulated recombination at loxP-containing DNA equences placed into the mammalian genome
-
Sauer, B. and Henderson, N. (1989) Cre-stimulated recombination at loxP-containing DNA equences placed into the mammalian genome. Nucleic Acids Res. 17, 147-161.
-
(1989)
Nucleic Acids Res
, vol.17
, pp. 147-161
-
-
Sauer, B.1
Henderson, N.2
-
36
-
-
0025360095
-
Targeted insertion of exogenous DNA into the eukaryotic genome by the Cre recombinase
-
Sauer, B. and Henderson, N. (1990) Targeted insertion of exogenous DNA into the eukaryotic genome by the Cre recombinase. New Biologist 2, 441-449.
-
(1990)
New Biologist
, vol.2
, pp. 441-449
-
-
Sauer, B.1
Henderson, N.2
-
37
-
-
0027485834
-
-
Wasserman, P. M. and DePamphilis, M. L, eds, Academic, San Diego, pp
-
Sauer, B. (1993) in Guide to Techniques in Mouse Development, Methods in Embryology, vol 225 (Wasserman, P. M. and DePamphilis, M. L., eds.), Academic, San Diego, pp. 890-900.
-
(1993)
Guide to Techniques in Mouse Development, Methods in Embryology
, vol.225
, pp. 890-900
-
-
Sauer, B.1
-
38
-
-
0021891053
-
The in vitro development of blastocyst-derived embryonic stem cell lines: Formation of visceral yolk sac, blood islands and myocardium
-
Doetschman, T. C., Eistetter, H., Katz, M., Schmidt, W., and Kemler, R. (1985) The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium. J. Embryol. Exp. Morph. 87, 27-45.
-
(1985)
J. Embryol. Exp. Morph
, vol.87
, pp. 27-45
-
-
Doetschman, T.C.1
Eistetter, H.2
Katz, M.3
Schmidt, W.4
Kemler, R.5
-
39
-
-
0024205842
-
Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells
-
Williams, R. L., Hilton, D. J., Pease, S., Willson, T. A., Stewart, C. L., Gearing, D. P., et al. (1988) Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature 336, 684-687.
-
(1988)
Nature
, vol.336
, pp. 684-687
-
-
Williams, R.L.1
Hilton, D.J.2
Pease, S.3
Willson, T.A.4
Stewart, C.L.5
Gearing, D.P.6
-
40
-
-
0003483954
-
-
Joyner, A. L, ed, Oxford University Press, Oxford, p
-
Wurst, W. and Joyner, A. L. (1993) Gene Targeting: A Practical Approach. (Joyner, A. L., ed.), Oxford University Press, Oxford, p. 33.
-
(1993)
Gene Targeting: A Practical Approach
, pp. 33
-
-
Wurst, W.1
Joyner, A.L.2
-
41
-
-
60349099803
-
Developmetal potential of mouse embryonic stem cells and inner cell mass: A comparison. [Abstract]
-
Heidelberg, August 21-25
-
Nagy, A., Merentes, E., Gocza, E., Ivanyi, E., and Rossant, J. (1991) Developmetal potential of mouse embryonic stem cells and inner cell mass: a comparison. [Abstract] Symposium of Mouse Molecular Genetics, Heidelberg, August 21-25, 1991.
-
(1991)
Symposium of Mouse Molecular Genetics
-
-
Nagy, A.1
Merentes, E.2
Gocza, E.3
Ivanyi, E.4
Rossant, J.5
-
42
-
-
0029566108
-
A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells
-
Schwenk, F., Baron, U., and Rajewsky, K. (1995) A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells. Nucleic Acids Res. 23, 5080,5081.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 5080-5081
-
-
Schwenk, F.1
Baron, U.2
Rajewsky, K.3
-
43
-
-
0028928854
-
Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase
-
Araki, K., Araki, M., Miyazaki, J., and Vassalli, P. (1995) Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase. Proc. Natl. Acad. Sci. USA 92, 160-164.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 160-164
-
-
Araki, K.1
Araki, M.2
Miyazaki, J.3
Vassalli, P.4
|