Quantitative determination of zidovudine diaryl phosphate triester pro-drugs in rat plasma by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis

Volumn 48, Issue 5, 2008, Pages 1417-1424

  Zhu, Meixiang ^a   Xie, Baoying ^b   Tang, Guo ^a   Hu, Anfu ^a   Fang, Meijuan ^b   Wu, Zhen ^a,b   Zhao, Yufen ^a  

^a Key Laboratory for Chemical Biology of Fujian Province   (China)

^b XIAMEN UNIVERSITY   (China)

Author keywords

Diaryl phosphate triesters of zidovudine; Multiple reaction monitoring; Pro drugs; Quantitative determination; Rat plasma

Indexed keywords

ESTER DERIVATIVE; PHOSPHATE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; PRODRUG; STAVUDINE; ZIDOVUDINE DERIVATIVE;

ACCURACY; ANALYTIC METHOD; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG CLEARANCE; DRUG DETERMINATION; DRUG HALF LIFE; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

ANIMALS; ANTI-HIV AGENTS; AREA UNDER CURVE; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; FEMALE; FREEZING; HALF-LIFE; MALE; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; PRODRUGS; QUALITY CONTROL; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; TIME FACTORS; ZIDOVUDINE;

EID: 58149503738     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2008.11.023     Document Type: Article

References (22)

1. Kolata G. Science 235 (1987) 1570
2. Kim J., Park S., Tretyakova N.Y., and Wagner C.R. Mol. Pharm. 2 (2005) 233-241
3. Van Aerschot A., Ni Z.G., Rozenski J., Claes P., De Clercq E., and Herdewijn P. Nucleos. Nucleot. 13 (1994) 1791-1800
4. Herdewijn P. Drug Discov. Today 2 (1997) 235-242
5. Ledneva R.K., Preobrazhenskaya N.N., Shinskii N.G., Shabarova Z.A., and Prokofev M.A. Dokl. Akad. Nauk. SSSR 193 (1970) 1308-1310
6. Manouilov K.K., Fedorov I.I., Boudinot F.D., White C.A., Kotra L.P., Schinazi R.F., Hong C.I.I., and Chu C.K. Antivir. Chem. Chemother. 6 (1995) 230-238
7. Manouilov K.K., White C.A., Boudinot F.D., Fedorov I.I., and Chu C.K. Drug Metab. Dispos. 23 (1995) 655-658
8. Moore K.H.P., Raasch R.H., Brouwer K.L.R., Opheim K., Cheeseman S.H., Eyster E., Lemon S.M., and Horst C.M. Antimicrob. Agents Chemother. 39 (1995) 2732-2737
9. McGuigan C., Davies M., Pathirana R.N., Mahmood N., and Hay A.J. Antivir. Res. 24 (1994) 69-77
10. Parang K., Wiebe L.I., and Knaus E.E. Curr. Med. Chem. 7 (2000) 995-1039
11. Wagner C.R., Iyer V.V., and McIntee E.J. Med. Res. Rev. 20 (2000) 417-451
12. McGuigan C., Pathirana R.N., Mahmood N., and Hay A.J. Bioorg. Med. Chem. Lett. 2 (1992) 701-704
13. McGuigan C., Nickson C., Petrik J., and Karpas A. FEBS Lett. 310 (1992) 171-174
14. McGuigan C., Pathirana R.N., Davies M.P.H., Balzarini J., and De Clercq E. Bioorg. Med. Chem. Lett. 4 (1994) 427-430
15. Compain S., Schlemmer D., Levi M., Pruvost A., Goujard C., Grassi J., and Benech H. J. Mass Spectrom. 40 (2005) 9-18
16. Uslu B., and Özkan S.A. Anal. Chim. Acta 466 (2002) 175-185
17. Perrin C., Coussot G., Lefebvre I., Périgaud C., and Fabre H. J. Chromatogr. A 1111 (2006) 139-146
18. Compain S., Durand-Gasselin L., Grassi J., and Benech H. J. Mass Spectrom. 42 (2007) 389-404
19. Rezk N.L., Abdel-Megeed M.F., and Kashuba A.D. Ther. Drug Monit. 29 (2007) 429-436
20. Lefebvre I., Puy J.Y., Perrin C., and Périgaud C. J. Chromatogr. B 858 (2007) 2-7
21. Goossens J.F., Foulon C., Villard A.L., Puy J.Y., Lefebvre I., Perigaud C., Vaccher C., and Bonte J.P. Biomed. Chromatogr. 19 (2005) 415-425
22. Robbins B.L., Poston P.A., Neal E.F., Slaughter C., and Rodman J.H. J. Chromatogr. B 850 (2006) 310-317