Improved method to quantify intracellular zidovudine mono- and triphosphate in peripheral blood mononuclear cells by liquid chromatography-tandem mass spectrometry

Journal of Mass Spectrometry

Volumn 42, Issue 3, 2007, Pages 389-404

  Compain, Séverine ^a,b   Durand Gasselin, Lucie ^b   Grassi, Jacques ^b   Benech, Henri ^b  

^a Parc d'Activité du Pas du Lac ^*  (France)

^b CEA SACLAY   (France)

Author keywords

AZT triphosphate; d4T triphosphate; Intracellular; LC MS MS; Specificity

Indexed keywords

BLOOD MONONUCLEAR CELLS; INTRACELLULAR TRIPHOSPHATE METABOLITES; NUCLEOSIDE ANALOGS;

BLOOD; CELLS; DISEASE CONTROL; DRUG THERAPY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

METABOLITES;

DRUG METABOLITE; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG; ZIDOVUDINE DERIVATIVE; ZIDOVUDINE MONOPHOSPHATE; ZIDOVUDINE TRIPHOSPHATE;

ACCURACY; ARTICLE; CALIBRATION; CONTROLLED STUDY; DRUG DETERMINATION; ELECTROSPRAY; HUMAN; HUMAN CELL; INTRACELLULAR SPACE; LIQUID CHROMATOGRAPHY; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; QUALITY CONTROL; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; VALIDATION STUDY;

CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; LEUKOCYTES, MONONUCLEAR; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; THYMINE NUCLEOTIDES; ZIDOVUDINE;

EID: 33947219897     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1176     Document Type: Article

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