Targeted disruption of the mouse Lipoma Preferred Partner gene

Biochemical and Biophysical Research Communications

Volumn 379, Issue 2, 2009, Pages 368-373

  Vervenne, Hilke B V K ^a   Crombez, Koen R M O ^a   Delvaux, Els L ^a   Janssens, Veerle ^a   Van de Ven, Wim J M ^a   Petit, Marleen M R ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Aberrant pregnancy; Female lethality; Fertility; Knockout; Lipoma Preferred Partner; LPP; Migration; TRIP6; ZRP 1; Zyxin

Indexed keywords

LIPOMA PREFERRED PARTNER PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CELL VIABILITY; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; FERTILITY; FIBROBLAST; GENE; GENE DISRUPTION; GENE EXPRESSION; GENE FUNCTION; KNOCKOUT MOUSE; LETHALITY; LIPOMA PREFERRED PARTNER GENE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROGENY; PROTEIN FUNCTION; TESTIS;

ANIMALS; CELL NUCLEUS; CYTOSKELETAL PROTEINS; EMBRYO LOSS; EMBRYONIC DEVELOPMENT; FEMALE; FERTILITY; FIBROBLASTS; GENE TARGETING; MALE; MICE; MICE, KNOCKOUT; PROMOTER REGIONS, GENETIC; PROTEIN BIOSYNTHESIS; REPRODUCTION; TESTIS; TRANSCRIPTION, GENETIC;

MUS;

EID: 58149501134     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.12.074     Document Type: Article

References (21)

1. Petit M.M.R., Mols R., Schoenmakers E.F., Mandahl N., and Van de Ven W.J. LPP, the preferred fusion partner gene of HMGIC in lipomas, is a novel member of the LIM protein gene family. Genomics 36 (1996) 118-129
2. Dahlen A., Mertens F., Rydholm A., Brosjo O., Wejde J., Mandahl N., and Panagopoulos I. Fusion, disruption, and expression of HMGA2 in bone and soft tissue chondromas. Mod. Pathol. 16 (2003) 1132-1140
3. Petit M.M.R., Swarts S., Bridge J.A., and Van de Ven W.J. Expression of reciprocal fusion transcripts of the HMGIC and LPP genes in parosteal lipoma. Cancer Genet. Cytogenet. 106 (1998) 18-23
4. Rogalla P., Lemke I., Kazmierczak B., and Bullerdiek J. An identical HMGIC-LPP fusion transcript is consistently expressed in pulmonary chondroid hamartomas with t(3;12)(q27-28;q14-15). Genes Chromosomes Cancer 29 (2000) 363-366
5. Daheron L., Veinstein A., Brizard F., Drabkin H., Lacotte L., Guilhot F., Larsen C.J., Brizard A., and Roche J. Human LPP gene is fused to MLL in a secondary acute leukemia with a t(3;11) (q28;q23). Genes Chromosomes Cancer 31 (2001) 382-389
6. Petit M.M.R., Fradelizi J., Golsteyn R.M., Ayoubi T.A., Menichi B., Louvard D., Van de Ven W.J., and Friederich E. LPP, an actin cytoskeleton protein related to zyxin, harbors a nuclear export signal and transcriptional activation capacity. Mol. Biol. Cell 11 (2000) 117-129
7. Petit M.M.R., Meulemans S.M., and Van de Ven W.J. The focal adhesion and nuclear targeting capacity of the LIM-containing lipoma-preferred partner (LPP) protein. J. Biol. Chem. 278 (2003) 2157-2168
8. Li B., Zhuang L., Reinhard M., and Trueb B. The lipoma preferred partner LPP interacts with alpha-actinin. J. Cell Sci. 116 (2003) 1359-1366
9. Guo B., Sallis R.E., Greenall A., Petit M.M.R., Jansen E., Young L., Van de Ven W.J., and Sharrocks A.D. The LIM domain protein LPP is a coactivator for the ETS domain transcription factor PEA3. Mol. Cell. Biol. 26 (2006) 4529-4538
10. Shepherd T.G., Kockeritz L., Szrajber M.R., Muller W.J., and Hassell J.A. The pea3 subfamily ets genes are required for HER2/Neu-mediated mammary oncogenesis. Curr. Biol. 11 (2001) 1739-1748
11. Laing M.A., Coonrod S., Hinton B.T., Downie J.W., Tozer R., Rudnicki M.A., and Hassell J.A. Male sexual dysfunction in mice bearing targeted mutant alleles of the PEA3 ets gene. Mol. Cell. Biol. 20 (2000) 9337-9345
12. Jin L., Kern M.J., Otey C.A., Wamhoff B.R., and Somlyo A.V. Angiotensin II, focal adhesion kinase, and PRX1 enhance smooth muscle expression of lipoma preferred partner and its newly identified binding partner palladin to promote cell migration. Circ. Res. 100 (2007) 817-825
13. Petit M.M.R., Lindskog H., Larsson E., Wasteson P., Athley E., Breuer S., Angstenberger M., Hertfelder D., Mattsson E., Nordheim A., Nelander S., and Lindahl P. Smooth muscle expression of lipoma preferred partner is mediated by an alternative intronic promoter that is regulated by serum response factor/myocardin. Circ. Res. 103 (2008) 61-69
14. Petit M.M.R., Meulemans S.M., Alen P., Ayoubi T.A., Jansen E., and Van de Ven W.J. The tumor suppressor Scrib interacts with the zyxin-related protein LPP, which shuttles between cell adhesion sites and the nucleus. BMC Cell Biol. 6 (2005) 1
15. Wada H., Iwasaki M., Sato T., Masai I., Nishiwaki Y., Tanaka H., Sato A., Nojima Y., and Okamoto H. Dual roles of zygotic and maternal Scribble1 in neural migration and convergent extension movements in zebrafish embryos. Development 132 (2005) 2273-2285
16. Montcouquiol M., Rachel R.A., Lanford P.J., Copeland N.G., Jenkins N.A., and Kelley M.W. Identification of Vangl2 and Scrb1 as planar polarity genes in mammals. Nature 423 (2003) 173-177
17. Murdoch J.N., Henderson D.J., Doudney K., Gaston-Massuet C., Phillips H.M., Paternotte C., Arkell R., Stanier P., and Copp A.J. Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse. Hum. Mol. Genet. 12 (2003) 87-98
18. Wang Y., and Nathans J. Tissue/planar cell polarity in vertebrates: new insights and new questions. Development 134 (2007) 647-658
19. Vervenne H.B., Crombez K.R., Lambaerts K., Carvalho L., Koppen M., Heisenberg C.P., Van de Ven W.J., and Petit M.M.R. Lpp is involved in Wnt/PCP signaling and acts together with Scrib to mediate convergence and extension movements during zebrafish gastrulation. Dev. Biol. 320 (2008) 267-277
20. Wakaguri H., Yamashita R., Suzuki Y., Sugano S., and Nakai K. DBTSS: database of transcription start sites, progress report 2008. Nucleic Acids Res. 36 (2008) D97-101
21. Hoffman L.M., Nix D.A., Benson B., Boot-Hanford R., Gustafsson E., Jamora C., Menzies A.S., Goh K.L., Jensen C.C., Gertler F.B., Fuchs E., Fassler R., and Beckerle M.C. Targeted disruption of the murine zyxin gene. Mol. Cell. Biol. 23 (2003) 70-79