Correlation of Bmi-1 expression and telomerase activity in human ovarian cancer

British Journal of Biomedical Science

Volumn 65, Issue 4, 2008, Pages 172-177

  Zhang, F B ^a   Sui, L H ^a   Xin, Tao ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

BMI1 protein, human; Ovarian neoplasms; Telomerase

Indexed keywords

BMI1 PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER STAGING; CARCINOGENESIS; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; ENZYME ACTIVITY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TELOMERIC REPEAT AMPLIFICATION PROTOCOL; TISSUE SECTION; WESTERN BLOTTING;

EID: 58149496634     PISSN: 09674845     EISSN: None     Source Type: Journal    
DOI: 10.1080/09674845.2008.11732824     Document Type: Article

References (26)

1. van Lohuizen M, Frasch M, Wientjens E, Berns A. Sequence similarity between the mammalian bmi-1 proto-oncogene and the Drosophila regulatory genes Psc and Su(z) 2 Nature 1991; 353 (6342): 353-5.
2. Jacobs JJ, Kieboom K, Marino S, DePinho RA, van Lohuizen M. The oncogene and polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink-4a locus. Nature 1999; 397 (6715): 164-8.
3. Mihara K, Chowdhury M, Nakaju N et al. Bmi-1 is useful as a novel molecular marker for predicting of myelodysplastic syndrome and patient prognosis. Blood 2006; 107 (1): 305-8.
4. ARF proteins. Cancer Lett 2004; 203 (2): 217-24.
5. Gerider CW, Blackburn EH. Identification of a specific telomere terminal transferase activity in Tetrehymena extracts. Cell 1985; 43 (5): 405-13.
6. Tahara H, Ya Sui W, Tahara F et al. Immunohistochemical detection of human telomerase catalytic component, hTERT, in human colorectal tumor and non-tumor tissue sections. Oncogene 1999; 18 (8): 1561-7.
7. Saito M, Handa K, Kiyono T et al. Immortalization of cementoblast progenitor cells with Bmi-1 and TERT. J Bone Miner Res 2005; 20 (1): 50-7.
8. Kim NW, Piatyszek MA, Prowse KR et al. Specific association of human telomerase activity with immortal cells and cancer. Science 1994; 266 (5193): 2011-5.
9. Arias AM. Epithelial mesenchymal interactions in cancer and development. Cell 2001; 105 (4): 425-31.
10. Park IK, Qian D, Kiel M et al. Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 2003; 423 (6937): 302-5.
11. Molosky AV, Pardal R, Iwashita T, Park IK, Clarke MF, Morrison SJ. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 2003; 425 (6961): 962-7.
12. Jacobs JJ, Scheijen B, Voncken JW, Kieboom K, Berns A, van Lohuizen M. Bmi-1 collaborates with c-myc in tumorigenesis by inhibiting c-myc-induced apoptosis via INK4/ARF. Genes Dev 1999; 13 (20): 2678-90.
13. Haupt Y, Alexander WS, Barri G, Klinken SP, Adams JM. Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E μ-myc transgenic mice. Cell 1991; 65 (5): 753?63.
14. Dimri GP, Martinez JL, Jacobs JJ et al. The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells. Cancer Res 2002; 62 (16): 4736-45.
15. Song LB, Zeng MS, Liao WT et al. Bmi-1 is a novel molecular marker of nasopharyngeal carcinoma progression and immortalizes primary human nasopharyngeal epithelial cells. Cancer Res 2006; 66 (12): 6225-32.
16. Datar RH, Naritoku WY, Li P et al. Analysis of telomerase activity in ovarian cystadenomas, low-malignant-potential tumors and invasive carcinomas. Gynecol Oncol 1999; 74 (3): 338-45.
17. Park TW, Riethdorf S, Riethdorf L, Löning T, Jänicke F. Differenrial telomerase activity expression of the telomerase catalytic sub-unit and telomerase-RNA in ovarian tumors. Int J Cancer 1999; 84 (4): 426-31.
18. Takeda Y, Mori T, Imabayashi H et al. Can the life span of human marrow stromal cells be prolonged by bmi-1, E6, E7 and/or telomerase without affecting cardiomyogenic differentiation. J Gene Med 2004; 6 (8): 833-45.
19. Ball AJ, Levine F. Telomere-independent cellular senescence in human fetal cardiomyocytes. Aging Cell 2005; 4 (1): 21-30.
20. Itahana K, Zou Y, Itahana Y et al. Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1. Mol Cell Biol 2003; 23 (1): 389-401.
21. Silva J, Garcia JM, Pena C et al. Implication of polycomb members Bmi-1, Mel-18 and Hpc-2 in the regulation of p16INK4a, p14ARF, h-TERT and c-Myc expression in primary breast carcinomas. Clin Cancer Res 2006; 12: 6929-36.
22. Liu L, Andrews LG, Tollefsbol TO. Loss of the human polycomb group protein BMI1 promotes cancer-specific cell death. Oncogene 2006; 25: 4370-5.
23. Ma Y, Cui W, Yang J et al. SALL4, a novel oncogene, is constitutively expressed in human acute myeloid leukemia (AML) and induces AML in transgenic mice. Blood 2006; 108: 2726-35.
24. Nowak K, Kerl K, Fehr D et al. BMI1 is a target gene of E2F-1 and is strongly expressed in primary neuroblastomas. Nucleic Acids Res 2006; 34: 1745-54.
25. Cui H, Hu B, Li T et al. Bmi-1 is essential for the tumorigenicity of neuroblastoma cells. Am J Pathol 2007; 170 (4): 1370-8.
26. Guo WJ, Datta S, Band V, Dimri GP. Mel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteins. Mol Biol Cell 2007; 18 (2): 536-46.