Antigenic complementarity between coxsackie virus and streptococcus in the induction of rheumatic heart disease and autoimmune myocarditis

Autoimmunity

Volumn 42, Issue 1, 2009, Pages 1-16

  Root Bernstein, Robert ^a   Vonck, Jessica ^a   Podufaly, Abigail ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Antigenic complementarity; Coxsackie virus; GAS; Myocarditis; Streptococcus A

Indexed keywords

ACTIN; BACTERIAL PROTEIN; BACTERIUM ANTIBODY; M PROTEIN; MYOSIN; VIRUS ANTIBODY; VIRUS PROTEIN;

AMINO ACID SEQUENCE; ANTIGEN RECOGNITION; ANTIGENICITY; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNE MYOCARDITIS; AUTOIMMUNITY; CONTROLLED STUDY; COXSACKIE VIRUS; CROSS REACTION; DISEASE SEVERITY; GENETIC COMPLEMENTATION; HUMAN; IMMUNOPATHOGENESIS; MIXED INFECTION; NONHUMAN; RHEUMATIC HEART DISEASE; SEQUENCE HOMOLOGY; STREPTOCOCCUS GROUP A;

ACTINS; AMINO ACID SEQUENCE; ANTIGENS, BACTERIAL; ANTIGENS, VIRAL; AUTOIMMUNE DISEASES; COXSACKIEVIRUS INFECTIONS; ENTEROVIRUS; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; MYOCARDITIS; RHEUMATIC HEART DISEASE; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS PYOGENES;

EID: 58149494419     PISSN: 08916934     EISSN: 1607842X     Source Type: Journal    
DOI: 10.1080/08916930802208540     Document Type: Article

References (84)

1. Rose, NR (1998) The role of infection in the pathogenesis of autoimmune disease. Semin Immunol, 10:1, pp. 5-13.
2. Cunningham, MW, Antone, SM, Gulizia, JM, McManus, BM, Fishetti, VA and Gauntt, CJ (1992) Cytotoxic and viral neutralizing antibodies crossreact with streptococcal M protein, enteroviruses, and human cardiac myosin. Proc Natl Acad Sci USA, 89:4, pp. 1320-1324.
3. Cunningham, MW (2004) T cell mimicry in inflammatory heart disease. Mol Immunol, 40, pp. 1121-1127.
4. Fairweather, D. and Rose, NR (2007) Coxsackivirus-induced myocarditis in mice: A model of autoimmune disease for studying immunotoxicity. Methods, 41, pp. 118-122.
5. Carapetis, JR, Steer, AC, Mulholland, EK and Weber, M. (2005) The global burden of group A streptococcal diseases. Lancet Infect Dis, 5:11, pp. 685-694.
6. Lee, GM and Wessels, MR (2006) Changing epidemiology of acute rheumatic fever in the United States. Clinical Infectious Diseases, 42, pp. 448-450.
7. Kaplan, EL and Bisno, AL (2006) Antecedent streptococcal infection in acute rheumatic fever. CID, 43, pp. 690-692.
8. Berrios, X., Qeusney, F., Morales, A., Blazquez, J., Lagomarsino, E. and Bisno, AL (1986) Acute rheumatic fever and poststreptococcal glomerulonephritis in an open population: Comparative studies of epidemiology and bacteriology. J Lab Clin Med, 108:6, pp. 535-542.
9. Centers for Disease Control and Prevention (2003) Outbreak of group A streptococcal pneumonia among Marine Corps Recruits, California. MMWR, 52:6, pp. 106-109.
10. Gorska, A., Urban, M., Glowinska, B. and Kowalewski, M. (1998) Czy zakazenie aciorkowcem grupy A jest wylaczna infekcyjna przyczyna goraczki reumatycznej?-opis przebiegu goraczki reumatycznej u 11-letniego chlopca ze wspolistniejaca infekcja wirusem Coxackie B1. Przegl Lek, 55:7, pp. 418-419.
11. Parasca, I., Damian, L. and Albu, A. (2006) Infectious muscle disease. Rom J Intern Med, 44:2, pp. 131-141.
12. Galvin, JE, Hemric, ME, Kosanke, SD, Factor, SM, Quinn, A. and Cunningham, MW (2002) Induction of myocarditis and valvulitis in Lewis rats by different epitopes of cardiac myosin and its implications in rheumatic carditis. Am J Pathol, 160, pp. 297-306.
13. Neu, N., Craig, S., Rose, NR, Alvarez, F. and Beisel, KW (1987) Coxsackievirus induced myocarditis in mice: Cardiac myosin autoantibodies do not cross-react with the virus. Clin Exp Immunol, 69, pp. 566-574.
14. Lang, SD and Singh, K. (1990) The sore throat. When to investigate and when to prescribe. Drugs, 40:6, pp. 854-862.
15. Soboleva, VD, Lozovskaya, LS, Alekseveva, VB, Belostotskaya, NP, Bushanskaya, NR and Kalinina, IN (1978) Coxsackie A 13 virus in the foci of rheumatism. J Hyg Epidemiol Microbiol Immunol, 22:2, pp. 195-202.
16. Pongpanich, B., Boonpucknavig, S., Wasi, C., Tanphaichitr, P. and Boonpucknavig, V. (1983) Immunopathology of acute rheumatic fever and rheumatic heart disease. The demonstration of coxsackie group B viral antigen in the myocardium. Clin Rheumatol, 2:3, pp. 217-222.
17. Boonpucknavig, S., Udomsangpetch, R. and Pongpanich, B. (1984) Immunological studies on acute rheumatic fever and rheumatic heart disease. J Clin Lab Immunol, 13:3, pp. 133-136.
18. Suresh, L., Chandrasekar, S., Rao, RS, Ravi, V. and Badrinath, S. (1981) Coxsackie virus and rheumatic fever. A correlative study. J Assoc Physicians India, 37:9, pp. 582-585.
19. Zaher, SR, Kassem, AS and Hughes, JJ (1993) Coxsackie virus infections in rheumatic fever. Indian J Pediatr, 60:2, pp. 289-298.
20. Vikerfors, T., Stjerna, A., Olcen, P., Malmcrona, R. and Magnius, L. (1988) Acute myocarditis. Serologic diagnosis, clinical findings and follow-up. Acta Med Scand, 223:1, pp. 45-52.
21. Higgins, PM (1992) Splenomegaly in acute infections due to group A streptococci and viruses. Epidemiol Infect, 109:2, pp. 199-209.
22. Novikov, I. (1983) O dignostike nervmaticheskikh miokarditov. Kardiologiia, 23:5, pp. 50-55.
23. Pearce, JM (1953) Effect of hemolytic toxin of streptococcus pyogenes on viral myocarditis in rabbit. AMA Arch Pathol, 56, pp. 113-122.
24. Kogut, EP, Livashova, NV, Bondarenk, AP, Zherdeva, AI and Shuvalova, IA (1978) Eksperimental'noe izuchenie koksaki-streptokokkovoi infektsii. Vopr Virusol, pp. 690-695.
25. Dale, JB and Beachey, EH (1985) Epitopes of streptococcal M proteins shared with cardiac myosin. J Exp Med, 162, pp. 583-592.
26. Krisher, K. and Cunningham, MW (1985) Myosin: A link between streptococci and heart. Science, 227, pp. 413-417.
27. Fae, KC, da Silva, DD, Oshiro, SE, Tanaka, AC, Pomerantzeff, PM, Douay, C., Chararon, D., Toubert, A., Cunningham, MW, Kalil, J. and Guilherme, L. (2006) Mimicry in recognition of cardiac myosin peptides by heart intralesional T cell clones from rheumatic heart disease. J Immunol, 176:9, pp. 5662-5670.
28. Cunningham, MW (2003) Autoimmunity and molecular mimicry in the pathogenesis of post-streptococcal heart disease. Front Biosci, 8, pp. s533-s544.
29. Wolfgram, LJ, Beisel, KW and Rose, NR (1985) Heart-specific autoantibodies following murine coxsackie B3 myocarditis. J Exp Med, 161, pp. 1112-1121.
30. Wolfgram, LJ, Beisel, KW, Herskowitz, A. and Rose, NR (1986) Variations in the susceptibility to coxsackie B3-induced myocarditis among different strains of mice. J Immunol, 136, pp. 1846-1853.
31. Takata, S., Nakamura, H., Umemoto, S., Yamaguchil, K., Sekine, T., Kato, T., Nishioka, K. and Matsuzaki, M. (2004) Identification of autoantibodies with the corresponding antigen for repetitive coxsackievirus infection-induced cardiomyopathy. Circ J, 68:7, pp. 677-682.
32. Latif, N., Zhang, H., Archard, LC, Yacoub, MH and Dunn, MJ (1999) Characterization of anti-heart antibodies in mice after infection with coxsackie B3 virus. Clin Immunol, 91:1, pp. 90-98.
33. Takeda, N. (2003) Cardiomyopathy: Molecular and immunological aspects (review). Int J Mol Med, 11:1, pp. 13-16.
34. De Scheerder, IK, De Buyzere, M., Delanghe, J., Maas, A., Clement, DL and Wieme, R. (1991) Humoral immune response against contractile proteins (actin and myosin) during cardiovascular disease. Eur Heart J, 12, pp. 88-94.
35. Huang, X. and Miller, W. (1991) A time-efficient, linear-space local similarity algorithm. Adv Appl Math, 12, pp. 337-357.
36. Rudensky, AY, Preston-Huriburt, P., Hoag, S-C, Balrow, A. and Janeway, CA (1991) Sequence analysis of peptides bound to MHC class II molecules. Nature, 353, pp. 622-627.
37. Root-Bernstein, RS (2002) Molecular complementarity III. Molecular complementarity as the basis for peptide hormone evolution. A bioinformatic case study of insulin, glucagon, and gastrin. J Theor Biol, 218, pp. 71-84.
38. Aydt, EM, Wolff, G. and Morano, I. (2007) Molecular modeling of the myosin-S1(A1) isoform. J Struct Biol, 159:1, pp. 158-163.
39. Gu, J., Xu, S. and Yu, LC (2002) A model of cross bridge attachment to actin in the A.M.ATP state based on X-ray diffraction from rabbit psoas muscle. Biophys J, 82:4, pp. 2123-2133.
40. Labbe, JP, Lelievre, S., Boyer, M. and Benyamin, Y. (1994) Interaction of skeletal-muscle myosin subfragment-1 with the actin-(338-348) peptide. Biochem J, 299:3, pp. 875-879.
41. Schroder, RR, Manstein, DJ, Jahn, W., Holden, H., Rayment, I., Holmes, KC and Spudich, JA (1993) Three-dimensional model of F-actin decorated with dichtostylium myosin S1. Nature, 364, pp. 171-174.
42. Agbulut, O., Huet, A., Neiderlander, N., Puceat, M., Menasche, P. and Colraut, C. (2007) Green fluorescent protein impairs actin-myosin interactions by binding to the actin binding site of myosin. JBC, 282:14, pp. 10465-10471.
43. Westall, FC and Root-Bernstein, RS (1983) An explanation of prevention and suppression of experimental allergic encephalomyelitis. Mol Immunol, 20, pp. 169-177.
44. Westall, FC and Root-Bernstein, RS (1986) The cause and prevention of postinfectious and postvaccinal encephalopathies in light of a new theory of autoimmunity. Lancet, 2, pp. 251-252.
45. Kion, TA and Hoffmann, GW (1991) Anti-HIV and anti-anti-MHC antibodies in alloimmune and autoimmune mice. Science, 253:5024, pp. 1138-1140.
46. Hoffmann, GW, Kion, TA and Grant, MD (1991) An idiotypic network model of AIDS immunopathogenesis. Proc Natl Acad Sci USA, 88:8, pp. 3060-3064.
47. Root-Bernstein, RS (1990) Multiple antigen-mediated autoimmunity (MAMA) in AIDS: A possible model for post-infectious autoimmunity. Res Immunol, 141, pp. 321-339.
48. Root-Bernstein, RS (1991) Self, nonself, and the paradoxes of autoimmunity. Organism and the development of self, pp. 159-209. Kluwer, Boston
49. Root-Bernstein, RS (2004) Antigenic complementarity among AIDS-associated infectious agents and molecular mimicry of lymphocyte proteins as inducers of lmphocytotoxic antibodies and circulating immune complexes. J Clin Virol, 315, pp. S16-S25.
50. Root-Bernstein, RS (2005) Antigenic complementarity between HIV and other AIDS-associated infections results in idiotype-antiidiotype antibody complexes that cross react with lymphocyte proteins. Vaccine, 23, pp. 2160-2163.
51. Root-Bernstein, RS (2007) Antigenic complementarity in the induction of autoimmunity: A general theory and review. Autoimmunity Rev, 6:5, pp. 272-277.
52. Root-Bernstein, RS and Dobbelstein, C. (2001) Insulin binds to glucagon forming a complex that is hyper-antigenic and inducing complementary antibodies having an idiotype-antiidiotype relationship. Autoimmunity, 33, pp. 153-169.
53. Root-Bernstein, RS and Couturier, J. (2006) Antigenic complementarity in the origins of autoimmunity: A general theory illustrated with a case study of idiopathic thrombocytopenia purpura. Clin Develop Immunol, 13, pp. 49-65.
54. Root-Bernstein, RS and Rallo, A. (2004) Antigenic complementarity resulting in idiotype-antiidiotype immune complexes: Possible contributor to AIDS pathogenesis and autoimmunity. Autoimmunity, 37, pp. 203-210.
55. Fujinami, RS, Oldstone, MB, Wroblewska, Z., Frankel, ME and Koprowski, H. (1983) Molecular mimicry in virus infection: Cross-reaction of measles virus phosphoprotein or of herpes simplex virus protein with human intermediate filaments. Proc Natl Acad Sci USA, 80:8, pp. 2346-2350.
56. Fujinami, RS and Oldstone, MB (1985) Amino acid homology between the encephalitogenic site of myelin basic protein and virus: Mechanism for autoimmunity. Science, 230, pp. 1043-1045.
57. Fuinami, RS, von Herrath, MG, Christen, U. and Whitton, JL (2006) Molecular mimicry, bystander activation, or viral persistence: Infections and autoimmune disease. Clin Microbiol Rev, 19:1, pp. 80-94.
58. McCoy, L., Tsunoda, I. and Fujinami, RS (2006) Multiple sclerosis and virus induced immune responses: Autoimmunity can be primed by molecular mimicry and augmented by bystander activation. Autoimmunity, 39:1, pp. 9-19.
59. Tsunoda, I., Libbey, JE and Fujinami, RS (2007) Sequential polymicrobial infections lead to CNS inflammatory disease: Possible involvement of bystander activation in heterologous immunity. J Neuroimmunol, 188:1, pp. 22-33.
60. Guilherm, L., Kalil, J. and Cunningham, M. (2006) Molecular mimicry in the autoimmune pathogenesis of rheumatic heart disease. Autoimmunity, 39, pp. 31-39.
61. Plotz, PH (1983) Autoantibodies are anti-idiotype antibodies to antiviral antibodies. Lancet, 2:8354, pp. 824-826.
62. Isenberg, D. and Shoenfeld, Y. (1986) Autoantibodies, idiotypes, anti-idiotypes and autoimmunity. Acta Haematolog, 76:2, pp. 95-100.
63. Pendergraft 3rd, WF, Preston, GA, Shah, RR, Tropsha, A., Carater Jr, CW, Jennette, JC and Falk, RJ (2004) Autoimmunity is triggered by cPR-3 (105-201), a protein complementary to human autoantigen proteinase-3. Nat Med, 10, pp. 72-79.
64. Pendergraft 3rd, WF, Jennette, JC, Ralk, RJ and Preston, GA (2005) Autoantigen complementarity: A new theory implicating complementary proteins as initiators of autoimmune disease. J Mol Med, 83, pp. 12-25.
65. Preston, GA, Pendergraft 3rd, WF and Falk, RJ (2005) New insights that link microbes with the generation of antineutrophil cytoplasmic autoantibodies: The theory of autoantigen complementarity. Curr Opin Nephrol Hypertens, 14:3, pp. 217-222.
66. McGuire, KL and Holmes, DS (2005) Role of complementary proteins in autoimmunity. Trends Immunol, 26, pp. 367-372.
67. Shoenfeld, Y. (2004) The idiotypic network in autommunity. Nat Med, 10, pp. 17-18.
68. Paque, RE (1992) Role of anti-idiotypic antibodies in inductin, regulation, and expression of coxsackievirus-induced myocarditis. Prog Med Virol, 39, pp. 204-227.
69. Paque, RE and Miller, R. (1988) Modulation of murine-coxsackie virus induced myocarditis using anti-idiotypes. Viral Immunol, 1, pp. 391-397.
70. Paque, RE and Miller, R. (1989) Polyclonal anti-idiotypes influence macrophage chemotaxis in coxsackie-virus induced murine myocarditis. J Leukocyte Biol, 45, pp. 79-86.
71. Paque, RE and Miller, R. (1991) Auto-antiidiotypes exhibit mimicry of myocyte antigens in autoimmune myocarditis. J Virol, 65:1, pp. 16-22.
72. Paque, RE and Miller, R. (1992) Adoptively transferred anti-idiotype pulsed B cells mediate autoimmune myocarditis. Inf Immun, 60:8, pp. 3396-3404.
73. Weremeichik, H., Moraska, A., Herzum, M., Weller, A. and Huber, SA (1991) Naturally occurring anti-idiotypic antibodies-mechanisms for autoimmunity and immunoregulation?. Eur Heart J, 12, pp. 154-157.
74. Karjalainen, J., Heikkila, J., Nieminen, MS, Jalanko, H., Kleemola, M., Lapinleimu, K. and Sahi, T. (1983) Etiology of mild acute infectious myocarditis. Relation to clinical features. Acta Med Scand, 213:1, pp. 65-73.
75. Iasakova, OI, Gorbunova, ZV, Reneva, TG, Khovanova, AM and Ivanova, AV (1976) Rezul'taty lecheniia revmatizma gama-globulinom, titrovannym k ekzofermentam beta-gemiliticheskogo Streptokokka i virusam Koksaki A13, A18 i B3. Ter Arkh, 48:11, pp. 93-99.
76. Meshalkin, EN, Khovanova, AM, Iavorovskaia, VE, Kelin, EP and Korotkova, MP (1979) Techenie revmaticheskogo protsessa u bol'nykh mitral'nymi porokami serdtsa posle pervichnykh i povtornykh kursov lecheniia titrovannym gamma-globulinom. Kardiologiia, 19:6, pp. 31-34.
77. Petelenz, T., Koziol, M., Friedek, D., Slominska-Petelenz, T., Trzeciak, J., Drazkiewicz, U., Tustanowski, J., Nolewajka, E. and Elertowicz, M. (1988) Determination of immune complexes in patients with acquired valvular heart disease. Cor Vasa, 30:4, pp. 23-271.
78. Gorina, LG and Vul'fovich, IuV (1996) Differentsiatsiia antigenov v sostave tsirkuliruiushchikh immunnykh kompleksov. Zh Mikrobiol Epidemiol Immunobiol, pp. 58-61.
79. Cristea, A., Rus, H., Niculescu, F., Bedeleanu, D. and Vlaicu, R. (1986) Characterization of circulating immune complexes in heart disease. Immunol Lett, 13:12, pp. 45-49.
80. Root-Bernstein, RS and Hobbs, SH (1993) Does HIV "piggyback" on viruses, bacteria, and sperm? Implications for transmission, synergism, and autoimmunity in AIDS. J Theor Biol, 160, pp. 249-264.
81. Huhn, GD, Gross, C., Schnurr, D., Preas, C., Yagi, S., Reagan, S., Paddock, C., Passaro, D. and Dworkin, MS (2003) Myocarditis outbreak among adults, Illinois. Emerg Infect Dis, 11, pp. 1621-1624.
82. Johnson, DR, Stevens, DL and Kaplan, EL (1992) Epidemiologic analysis of group A streptococcal serotypes associated with severe systemic infections, rheumatic fever, or uncomplicated pharyngitis. J Infec Dis, 166, pp. 374-382.
83. Veasy, LG, Wiedmeier, Se, Orsmond, GS, Ruttenberg, HD, Boucek, MM, Roth, SJ, Tait, VF, Thompson, JA, Daly, JA and Kaplan, EL (1987) Resurgence of acute rheumatic fever in the intermountain area of the United States. N Engl J Med, 316, pp. 421-427.
84. Wang, HY, Zhao, H., Song, LF, Huang, WL, Niu, CL, Li, ZX, Yang, CF, Liu, XB, Liu, JH, Yang, L., Zhao, S., Ren, JM, Shi, GQ, Zhang, J., Pu, JL, Yang, YJ and Zeng, G. (2007) Pathological study of unexpected sudden death clustered in family or village in Yunnan province: Report of 29 cases of autopsy. Zhonghua Yi Xue Za Zhi, 87, pp. 2209-2214.