Bio-assay guided isolation and identification of anti-Alzheimer active compounds from the root of Angelica sinensis

Food Chemistry

Volumn 114, Issue 1, 2009, Pages 246-252

  Ho, Cheng Chang ^a   Kumaran, Alaganandam ^a   Hwang, Lucy Sun ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Amyloid peptide; Angelica sinensis; Anti Alzheimer; dPC 12 cells; DPPH

Indexed keywords

EID: 58149485189     PISSN: 03088146     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.foodchem.2008.09.046     Document Type: Article

References (30)

1. 1-42. Journal of Neuroinflammation 1 (2004) 4
2. Beck J.J., and Stermitz F.R. Addition of methyl thioglycolate and benzylamine to (Z)-ligustilide, a bioactive unsaturated lactone constituent of several herbal medicines. An improved synthesis of (Z)-ligustilide. Journal of Natural Products 58 (1995) 1047-1055
3. Choi S.J., Kim M.J., Heo H.J., Kim H.K., Hong B., Kim C.J., et al. Protective effect of Rosa laevigata against amyloid beta peptide-induced oxidative stress. Amyloid 13 (2006) 6-12
4. Deng S., Chen S.N., Yao P., Nikolic D., van Breemen R.B., Bolton J.L., et al. Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis. Journal of Natural Products 69 (2006) 536-541
5. Durairajan S.S., Yuan Q., Xie L., Chan W.S., Kum W.F., Koo I., et al. Salvianolic acid B inhibits Aβ fibril formation and disaggregates preformed fibrils and protects against Aβ-induced cytotoxicity. Neurochemistry International 52 (2008) 741-750
6. Heo H.J., Kim D.O., Choi S.J., Shin D.H., and Lee C.Y. Potent inhibitory effect of flavonoids in Scutellaria baicalensis on amyloid β protein-induced neurotoxicity. Journal of Agricultural and Food Chemistry 52 (2004) 4128-4132
7. Huang, S. H., Lin, C. M., & Chiang, B. H. (in press). Protective effects of Angelica sinensis extract on amyloid β-peptide-induced neurotoxicity. Phytomedicine. doi:10.1016/j.phymed.2008.02.022.
8. Kanski J., Aksenova M., Stoyanova A., and Butterfield D.A. Ferulic acid antioxidant protection against hydroxyl and peroxyl radical oxidation in synaptosomal and neuronal cell culture system in vitro: structure-activity studies. Journal of Nutritional Biochemistry 13 (2002) 273-281
9. Kim D.S.H.L., Park S.Y., and Kim J.K. Curcuminoids from Curcuma longa L. (Zingiberaceae) that protect PC12 rat pheochromocytoma and normal human umbilical vein endothelial cells from βA(1-42) insult. Neuroscience Letters 303 (2001) 57-61
10. Kuang X., Yao Y., Du J.R., Liu Y.X., Wang C.Y., and Qian Z.M. Neuroprotective role of Z-ligustilide against forebrain ischemic injury in ICR mice. Brain Research 1102 (2006) 145-153
11. Kumar U., Dunlop D.M., and Richardson J.S. The acute neurotoxic effect of β-amyloid on mature cultures of rat hippocampal neurons is attenuated by the anti-oxidant U-78517F. International Journal of Neuroscience 79 (1994) 185-190
12. Leung H.W., Kuo C.L., Yang W.H., Lin C.H., and Lee H.Z. Antioxidant enzymes activity involvement in luteolin-induced human lung squamous carcinoma CH27 cell apoptosis. European Journal of Pharmacology 534 (2006) 12-18
13. Li X.D., and Buccafusco J.J. Effect of β-amyloid peptide 1-42 on the cytoprotective action mediated by α7 nicotinic acetylcholine receptors in growth factor-deprived differentiated PC-12 cells. Journal of Pharmacology and Experimental Therapeutics 307 (2003) 670-675
14. Lu X.H., Liang H., and Zhao Y.Y. Isolation and identification of the ligustilide compounds from the root of Angelica sinensis. Zhongguo Zhong Yao Za Zhi 28 (2003) 423-425
15. McKeage M.J. Gold opens mitochondrial pathways to apoptosis. British Journal of Pharmacology 136 (2002) 1081-1082
16. Oken B.S., Storzbach D.M., and Kaye J.A. The efficacy of Ginkgo biloba on cognitive function in Alzheimer disease. Archives of Neurology 55 (1998) 1409-1415
17. Ono K., Hamaguchi T., Naiki H., and Yamada M. Anti-amyloidogenic effects of antioxidants: implications for the prevention and therapeutics of Alzheimer's disease. Biochimica et Biophysica Acta 1762 (2006) 575-586
18. Ou S., and Kwok K.C. Ferulic acid: pharmaceutical functions, preparation and applications in foods. Journal of the Science of Food and Agriculture 84 (2004) 1261-1269
19. Peng H.Y., Du J.R., Zhang G.Y., Kuang X., Liu Y.X., Qian Z.M., et al. Neuroprotective effect of Z-ligustilide against permanent focal ischemic damage in rats. Biological & Pharmaceutical Bulletin 30 (2007) 309-312
20. Skolnick A.A. Old Chinese herbal medicine used for fever yields possible new Alzheimer disease therapy. Journal American Medical Association 277 (1997) 776
21. Smith J.V., and Luo Y. Elevation of oxidative free radicals in Alzheimer's disease models can be attenuated by Ginkgo biloba extract EGb 761. Journal of Alzheimer's Disease 5 (2003) 287-300
22. Tieraona L.D. Menopause: a review of botanical dietary supplements. The American Journal of Medicine 118 (2005) 98S-108S
23. Vaudry D., Stork P.J., Lazarovici P., and Eiden L.E. Signaling pathways for PC12 cell differentiation: making the right connections. Science 296 (2002) 1648-1649
24. Wagner H., Bladt S., and Zgainski E.M. Plant drug analysis. A thin layer chromatography atlas (1984), Springer-Verlag, New York
25. Yan J.J., Cho J.Y., Kim H.S., Kim K.L., Jung J.S., Huh S.O., et al. Protection against β-amyloid peptide toxicity in vivo with long-term administration of ferulic acid. British Journal of Pharmacology 133 (2001) 89-96
26. Yang X., Zhao Y., Li G., Wang Z., and Lv Y. Chemical composition and immuno-stimulating properties of polysaccharide biological response modifier isolated from Radix Angelica sinensis. Food Chemistry 106 (2008) 269-276
27. Yu Y., Du J.R., Wang C.Y., and Qian Z.M. Protection against hydrogen peroxide-induced injury by Z-ligustilide in PC12 cells. Experimental Brain Research 184 (2008) 307-312
28. Zhao G.R., Zhang H.M., Ye T.X., Xiang Z.J., Yuan Y.J., Guo Z.X., et al. Characterization of the radical scavenging and antioxidant activities of danshensu and salvianolic acid B. Food and Chemical Toxicology 46 (2008) 73-81
29. Zhu X., Raina A.K., Lee H.G., Chao M., Nunomura A., Tabaton M., et al. Oxidative stress and neuronal adaptation in Alzheimer disease: The role of SAPK pathways. Antioxidants & Redox Signaling 5 (2003) 571-576
30. Zschocke S., Liu J.H., Stuppner H., and Bauer R. Comparative study of roots of Angelica sinensis and related umbelliferous drugs by thin layer chromatography, high-performance liquid chromatography, and liquid chromatography-mass spectrometry. Phytochemical analysis 9 (1998) 283-290