PARP-1 inhibits glycolysis in ischemic kidneys

Journal of the American Society of Nephrology

Volumn 20, Issue 1, 2009, Pages 95-103

  Devalaraja Narashimha, Kishor ^a   Padanilam, Babu J ^a,b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IODOACETIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL HYPOXIA; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; GLYCOLYSIS; KIDNEY ISCHEMIA; KIDNEY PROXIMAL TUBULE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 58149484055     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2008030325     Document Type: Article

References (49)

1. Molitoris BA, Sandoval R, Sutton TA: Endothelial injury and dysfunction in ischemic acute renal failure. Crit Care Med 30: S235-S240, 2002
2. Bonventre JV: Mechanisms of ischemic acute renal failure. Kidney Int 43: 1160-1178, 1993
3. Yamamoto K, Wilson DR, Baumal R: Outer medullary circulatory defect in ischemic acute renal failure. Am J Pathol 116: 253-261, 1984
4. Venkatachalam MA, Bernard DB, Donohoe JF, Levinsky NG: Ischemic damage and repair in the rat proximal tubule: Differences among the S1, S2, and S3 segments. Kidney Int 14: 31-49, 1978
5. Shanley PF, Rosen MD, Brezis M, Silva P, Epstein FH, Rosen S: Topography of focal proximal tubular necrosis after ischemia with reflow in the rat kidney. Am J Pathol 122: 462-468, 1986
6. Lieberthal W, Nigam SK: Acute renal failure: I. Relative importance of proximal vs. distal tubular injury. Am J Physiol 275: F623-F631, 1998
7. Witzgall R, Brown D, Schwarz C, Bonventre JV: Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney: Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells. J Clin Invest 93: 2175-2188, 1994
8. Safirstein R: Gene expression in nephrotoxic and ischemic acute renal failure. J Am Soc Nephrol 4: 1387-1395, 1994
9. Ueda N, Kaushal GP, Shah SV: Recent advances in understanding mechanisms of renal tubular injury. Adv Ren Replace Ther 4: 17-24, 1997
10. Walker LM, York JL, Imam SZ, Ali SF, Muldrew KL, Mayeux PR: Oxidative stress and reactive nitrogen species generation during renal ischemia. Toxicol Sci 63: 143-148, 2001
11. Chien CT, Lee PH, Chen CF, Ma MC, Lai MK, Hsu SM: De novo demonstration and co-localization of free-radical production and apoptosis formation in rat kidney subjected to ischemia/reperfusion. J Am Soc Nephrol 12: 973-982, 2001
12. Berger NA: Poly(ADP-ribose) in the cellular response to DNA damage. Radiat Res 101: 4-15, 1985
13. Zheng J, Devalaraja-Narashimha K, Singaravelu K, Padanilam BJ: Poly-(ADP-ribose) polymerase-1 gene ablation protects mice from ischemic renal injury. Am J Physiol Renal Physiol 288: F387-F398, 2005
14. Devalaraja-Narashimha K, Singaravelu K, Padanilam BJ: Poly(ADP-ribose) polymerase-mediated cell injury in acute renal failure. Pharmacol Res 52: 44-59, 2005
15. Martin DR, Lewington AJ, Hammerman MR, Padanilam BJ: Inhibition of poly(ADP-ribose) polymerase attenuates ischemic renal injury in rats. Am J Physiol Regul Integr Comp Physiol 279: R1834-R1840, 2000
16. Filipovic DM, Meng X, Reeves WB: Inhibition of PARP prevents oxidant-induced necrosis but not apoptosis in LLC-PK1 cells. Am J Physiol 277: F428-F436, 1999
17. Paschen W, Olah L, Mies G: Effect of transient focal ischemia of mouse brain on energy state and NAD levels: No evidence that NAD depletion plays a major role in secondary disturbances of energy metabolism. J Neurochem 75: 1675-1680, 2000
18. Wright SC, Wei QS, Kinder DH, Larrick JW: Biochemical pathways of apoptosis: Nicotinamide adenine dinucleotide-deficient cells are resistant to tumor necrosis factor or ultraviolet light activation of the 24-kD apoptotic protease and DNA fragmentation. J Exp Med 183: 463-471, 1996
19. Bagnasco S, Good D, Balaban R, Burg M: Lactate production in isolated segments of the rat nephron. Am J Physiol 248: F522-F526, 1985
20. Mohr S, Stamler JS, Brune B: Mechanism of covalent modification of glyceraldehyde-3-phosphate dehydrogenase at its active site thiol by nitric oxide, peroxynitrite and related nitrosating agents. FEBS Lett 348: 223-227, 1994
21. Zhang J, Snyder SH: Nitric oxide stimulates auto-ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase. Proc Natl Acad Sci U S A 89: 9382-9385, 1992
22. Dimmeler S, Lottspeich F, Brune B: Nitric oxide causes ADP-ribosylation and inhibition of glyceraldehyde-3-phosphate dehydrogenase. J Biol Chem 267: 16771-16774, 1992
23. Du X, Matsumura T, Edelstein D, Rossetti L, Zsengeller Z, Szabo C, Brownlee M: Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells. J Clin Invest 112: 1049-1057, 2003
24. Gobeil S, Boucher CC, Nadeau D, Poirier GG: Characterization of the necrotic cleavage of poly(ADP-ribose) polymerase (PARP-1): Implication of lysosomal proteases. Cell Death Differ 8: 588-594, 2001
25. Yoon YS, Kim JW, Kang KW, Kim YS, Choi KH, Joe CO: Poly(ADPribosyl) ation of histone H1 correlates with internucleosomal DNA fragmentation during apoptosis. J Biol Chem 271: 9129-9134, 1996
26. Lash LH, Tokarz JJ, Chen Z, Pedrosi BM, Woods EB: ATP depletion by iodoacetate and cyanide in renal distal tubular cells. J Pharmacol Exp Ther 276: 194-205, 1996
27. Lemasters JJ, DiGuiseppi J, Nieminen AL, Herman B: Blebbing, free Ca2+ and mitochondrial membrane potential preceding cell death in hepatocytes. Nature 325: 78-81, 1987
28. Hernandez-Fonseca K, Cardenas-Rodriguez N, Pedraza-Chaverri J, Massieu L: Calcium-dependent production of reactive oxygen species is involved in neuronal damage induced during glycolysis inhibition in cultured hippocampal neurons. J Neurosci Res 86: 1768-1780, 2008
29. Hurst RD, Azam S, Hurst A, Clark JB: Nitric-oxide-induced inhibition of glyceraldehyde-3-phosphate dehydrogenase may mediate reduced endothelial cell monolayer integrity in an in vitro model blood-brain barrier. Brain Res 894: 181-188, 2001
30. Shanley PF, Brezis M, Spokes K, Silva P, Epstein FH, Rosen S: Differential responsiveness of proximal tubule segments to metabolic inhibitors in the isolated perfused rat kidney. Am J Kidney Dis 7: 76-83, 1986
31. Fukuhara Y, Yamamoto S, Yano F, Orita Y, Fujiwara Y, Ueda N, Kamada T, Noguchi T, Tanaka T: Changes in activities and mRNA levels of glycolytic enzymes of ischemia-reperfused rat kidney. Contrib Nephrol 95: 222-228, 1991
32. Ruegg CE, Mandel LJ: Bulk isolation of renal PCT and PST: II. Differential responses to anoxia or hypoxia. Am J Physiol 259: F176-F185, 1990
33. Vandewalle A, Wirthensohn G, Heidrich HG, Guder WG: Distribution of hexokinase and phosphoenolpyruvate carboxykinase along the rabbit nephron. Am J Physiol 240: F492-F500, 1981
34. Knight RJ, Kofoed KF, Schelbert HR, Buxton DB: Inhibition of glyceraldehyde-3-phosphate dehydrogenase in post-ischaemic myocardium. Cardiovasc Res 32: 1016-1023, 1996
35. Gstraunthaler G, Seppi T, Pfaller W: Impact of culture conditions, culture media volumes, and glucose content on metabolic properties of renal epithelial cell cultures: Are renal cells in tissue culture hypoxic? Cell Physiol Biochem 9: 150-172, 1999
36. Ruegg CE, Mandel LJ: Bulk isolation of renal PCT and PST: I. Glucose-dependent metabolic differences. Am J Physiol 259: F164-F175, 1990
37. Didlake R, Kirchner KA, Lewin J, Bower JD, Markov AK: Attenuation of ischemic renal injury with fructose 1,6-diphosphate. J Surg Res 47: 220-226, 1989
38. Kacser H, Burns JA: Molecular democracy: Who shares the controls? Biochem Soc Trans 7: 1149-1160, 1979
39. Polosukhina D, Singaravelu K, Padanilam BJ: Activation of protein kinase C isozymes protects LLCPK1 cells from H2O2 induced necrotic cell death. Am J Nephrol 23: 380-389, 2003
40. Kim BS, Chen J, Weinstein T, Noiri E, Goligorsky MS: VEGF expression in hypoxia and hyperglycemia: Reciprocal effect on branching angiogenesis in epithelial-endothelial co-cultures. J Am Soc Nephrol 13: 2027-2036, 2002
41. Saikumar P, Dong Z, Patel Y, Hall K, Hopfer U, Weinberg JM, Venkatachalam MA: Role of hypoxia-induced Bax translocation and cytochrome c release in reoxygenation injury. Oncogene 17: 3401-3415, 1998
42. Wei Q, Alam MM, Wang MH, Yu F, Dong Z: Bid activation in kidney cells following ATP depletion in vitro and ischemia in vivo. Am J Physiol Renal Physiol 286: F803-F809, 2004
43. Tentori L, Leonetti C, Scarsella M, D'Amati G, Vergati M, Portarena I, Xu W, Kalish V, Zupi G, Zhang J, Graziani G: Systemic administration of GPI 15427, a novel poly(ADP-ribose) polymerase-1 inhibitor, increases the antitumor activity of temozolomide against intracranial melanoma, glioma, lymphoma. Clin Cancer Res 9: 5370-5379, 2003
44. Di Paola R, Mazzon E, Xu W, Genovese T, Ferrraris D, Muia C, Crisafulli C, Zhang J, Cuzzocrea S: Treatment with PARP-1 inhibitors, GPI 15427 or GPI 16539, ameliorates intestinal damage in rat models of colitis and shock. Eur J Pharmacol 527: 163-171, 2005
45. Tao Y, Howlett A, Klein C: Nitric oxide regulation of glyceraldehyde-3-phosphate dehydrogenase activity in Dictyostelium discoideum cells and lysates. Eur J Biochem 224: 447-454, 1994
46. Zhang J: Use of biotinylated NAD to label and purify ADP-ribosylated proteins. Methods Enzymol 280: 255-265, 1997
47. Smith S, Giriat I, Schmitt A, de Lange T: Tankyrase, a poly(ADP-ribose) polymerase at human telomeres. Science 282: 1484-1487, 1998
48. Ditsworth D, Zong WX, Thompson CB: Activation of poly(ADP)-ribose polymerase (PARP-1) induces release of the pro-inflammatory mediator HMGB1 from the nucleus. J Biol Chem 282: 17845-17854, 2007
49. Uliasz TF, Hewett SJ: A microtiter Trypan blue absorbance assay for the quantitative determination of excitotoxic neuronal injury in cell culture. J Neurosci Methods 100: 157-163, 2000