Effect of interleukin-1 receptor antagonist gene deletion on male mouse fertility

Endocrinology

Volumn 150, Issue 1, 2009, Pages 295-303

  Ganaiem, Masaood ^a   AbuElhija, Mahmoud ^a   Lunenfeld, Eitan ^b   Cherniy, Nataly ^a   Weisze, Neomi ^b   Itach, Sarit Bar Sheshet ^c   Breitbart, Haiem ^c   Apte, Ronnie ^a   Huleihel, Mahmoud ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^c BAR ILAN UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM IONOPHORE; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA;

ACROSOME REACTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIDIDYMIS; FEMALE; FERTILIZATION; FERTILIZATION IN VITRO; GENE DELETION; IN VITRO STUDY; KNOCKOUT MOUSE; MALE; MALE FERTILITY; MATE CHOICE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROGENY; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR GENE; SEMEN ANALYSIS; SPECIES COMPARISON; SPERMATOGENESIS; SPERMATOZOON CAPACITATION; SPERMATOZOON DENSITY; SPERMATOZOON MOTILITY; SPERMATOZOON PENETRATION; TESTIS FUNCTION; TESTIS WEIGHT; WILD TYPE;

ACROSOME REACTION; ACTINS; ANIMALS; CALCIMYCIN; EPIDIDYMIS; FEMALE; FERTILITY; FERTILIZATION; FERTILIZATION IN VITRO; GENE DELETION; INTERLEUKIN-1; MALE; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; POLYMERASE CHAIN REACTION; PREGNANCY; RECEPTORS, INTERLEUKIN-1 TYPE I; SPERM COUNT; SPERMATOZOA; TESTIS;

EID: 58149478504     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2008-0848     Document Type: Article

References (67)

1. Dinarello CA 1996 Biologic basis for interleukin-1 in disease. Blood 87:2095-2147
2. Roux-Lombard P 1998 The interleukin-1 family. Eur Cytokine Netw 9:565-576
3. Dinarello CA 1998 Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist. Int Rev Immunol 16:457-499
4. Dinarello CA 2005 Blocking IL-1 in systemic inflammation. J Exp Med 201: 1355-1359
5. Skinner MK 1991 Cell-cell interactions in the testis. Endocr Rev 12:45-77
6. de Krester D, Loveland KL, Meinhardt A, Simorangkir D, Wreford N 1998 Sperrnatogenesis. Hum Reprod 13(Suppl 1):1-8
7. Huleihel M, AbuElhija M, Lunenfeld E 2007 In vitro culture of testicular germ cells: regulatory factors and limitations. Growth Factors 25:236-252
8. Lunenfeld E, Zeyse D, Huleihel M 1998 Cytokines in the testis, human sperm cells, and semen. Assist Reprod 9:157-165
9. Huleihel M, Lunenfeld E 2004 Regulation of spermatogenesis by paracrine/autocrine factors. Asian J Androl 6:259-268
10. Piquet-Pellorce C, Gomez E, Cudicini C, Stephan JP, Dejucq N, Jegou B 1995 Cytokines and spermatogenesis. In: Hedon B, Bringer J, Mares P, eds. Fertility and sterility today: a current overview: proceedings of the 15th World Congress on Fertility and Sterility, Montpellier, France, 17-22 September 1995. New York: Parthenon Publishing Group; 249
11. Khan S, Soder O, Syed V, Gustafsson K, Lindh M, Ritzen EM 1987 The rat testis produces large amounts of interleukin-1-like factor. Int J Androl 10: 495-503
12. Khan SA, Schmidt K, Hallin P, Di Pauli R, De Geyter C, Nieschlag E 1988 Human testis cytosol and ovarian follicular fluid contain high amounts of interleukin-1-like factors. Mol Cell Endocrinol 58:221-230
13. Huleihel M, Lunenfeld E, Blindman A, Prinsloo I, Potashnik G 2003 Over expression of interleukin-1 a, interleukin-1β and interleukin-1 receptor antagonist in testicular tissues from sexually immature mice as compared to adult mice. Eur Cytokine Netw 14:27-33
14. Cudicini C, Lejeune H, Gomez E, Bosnians E, Ballet F, Saez J, Jegou B 1997 Human Leydig cells and Sertoli cells are producers of interleukins-1 and - 6. J Clin Endocrinol Metab 82:1426-1433
15. Wang DL, Nagpal ML, Calkins JH, Chang WW, Sigel MM, Lin T 1991 Interleukin-1 β induces interleukin-1α messenger ribonucleic acid expression in primary cultures of Leydig cells. Endocrinology 129:2862-2866
16. Kem S, Robertson SA, Mau VJ, Maddocks S 1995 Cytokine secretion by macrophages in the rat testis. Biol Reprod 53:1407-1416
17. Huleihel M, Lunenfeld E, Zeyse D, Beck M, Prinsloo I, Potashnik G, Mazor M 2001 Immunohistochemical staining of IL-1 α and IL-1 receptor antagonist but not IL-1β in cultures of Sertoli cells. Am J Reprod Immunol 45:135-141
18. Zeyse D, Lunenfeld E, Beck M, Prinsloo I, Huleihel M 2000 Interleukin-1 receptor antagonist is produced by Seitoli cells in vitro. Endocrinology 141: 1521-1527
19. Wang JE, Josefsen GM, Hansson V, Haugen TB 1998 Residual bodies and 1L-Iα stimulate expression of mRNA for IL-lα and IL-1 receptor type I in cultured rat Sertoli cells. Mol Cell Endocrinol 137:139-144
20. Haugen TB, Landmark BF, Josefsen GM, Hansson V, Hogset A 1994 The mature form of interleukin-1 α is constitutively expressed in immature male germ cells from rat. Mol Cell Endocrinol 105:R19-R23
21. Huleihel M, Lunenfeld E, Horowitz S, Levy A, Poashnik G, Glezerman M 2000 Capacitation of mouse spermatozoa. 1. Correlation between the capacitation state and protein tyrosine phosphorylation Involvement of serum and LPS in the production of interleukin-1- and interleukin-6-like molecules by human sperm cells. Am J Reprod Immunol 43:41-46
22. Huleihel M, Lunenfeld E, Horowitz S, Levy A, Potashnik G, Glezerman M 2000 Production of 1L-1-Iike molecules by human sperm cells. Fertil Steril 73:1132-1137
23. Zeyse D, Lunenfeld E, Beck M, Prinsloo I, Huleihel M 2000 Induction of interleukin-1α production in murine Sertoli cells by interleukin-1. Biol Reprod 62:1291-1296
24. Takao T, Mitchell WM, Tracey DE, DeSouza EB 1990 Identification of interleukin-1 receptors in mouse testis. Endocrinology 127:251-258
25. Gomez E, Morel G, Cavalier A, Lienard MO, Haour F, Courtens JL, Jegou, B 1997 Type I and type II interleukin-1 receptor expression in rat, mouse, and human testes. Biol Reprod 56:1513-1526
26. Durum S, Oppenheim JJ 1993 Pro-inflammatory cytokines and immunity. In: Paule WE, ed. Fundamental immunology. 3rded. New York: Raven Press; 801
27. Hedger MP, Meinhardt A 2003 Cytokines and immune-testicular axis. J Reprod Immunol 58:1-15
28. Jonsson CK, Setchell BP, Martinelle N, Svechnikov K, Soder O 2001 Endotoxin-induced interleukin 1 expression in testicular macrophages is accompanied by downregulation of the constitutive expression in Seitoli cells. Cytokine 14:283-288
29. Fijak M, Meinhardt A 2006 The testis in immune privelege. Immunol Rev 213:66-81
30. Yanagimachi R 1994 Mammalian fertilization. In: Knobil E, Neill JD, eds. The physiology of reproduction. New York: Raven Press; 189-317
31. Dimitrov DG, Petrovska M 1996 Effect of products of activated immune cells and recombinant cytokines on spontaneous and ionophore-induced acrosome reaction. Am J Reprod Immunol 36:150-156
32. Naz RK, Kaplan P 1994 Increased levels of interleukin-6 in seminal plasma of infertile men. J Androl 15:220-227
33. Horai R, Asano M, Sudo K, Kanuka H, Suzuki M, Nishihara M, Takahashi M, Iwakura Y 1998 Production of mice deficient in genes for interleukin (IL)-1α, IL-1β, IL-1α/β, and IL-1 receptor antagonist shows that IL-1β is crucial in turpentine-induced fever development and glucocorticoid secretion. J Exp Med 187:1463-1475
34. Brener E, Rubinstein S, Cohen G, Shternall K, Rivlin J, Breibart H 2003 Remodeling of the actin cytoskeleton during mammalian sperm capacitation and acrosome reaction. Biol Reprod 68:837-845
35. Visconti PE, Bailey JL, Moore GD, Pan D, Olds-Clarke P, Kopf GS 1995 Capacitation of mouse spermatozoa. 1. Correlation between the capacitation state and protein tyrosine phosphorylation. Development 121:1129-1137
36. Baker SS, Thomas M, Thaler CD 2004 Sperm membrane dynamics assessed by changes, in lectin fluorescence before and after capacitation. J Androl 25: 744-751
37. Schäfer S, Holzmann A 2000 The use of transmigration and spermac stain to evaluate epididymal cat spermatozoa. Anirn Reprod Sci 59:201-211
38. Bradford MM 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 7:248-255
39. Watson JM, Lofquist AK, Rinehart CA, Olsen JC, Makarov SS, Kaufman DG, Haskill JS 1995 The intracellular IL-1 receptor antagonist alters IL-1-inducible gene expression without blocking exogenous signaling by IL-1β. J Immunol 155:4467-4475
40. Granowitz EV, Clark BD, Vannier E, Callahan MV, Dinarello CA 1992 Effect of interleukin-1 (IL-1) blockade on cytokine synthesis: 1. IL-1 receptor antagonist inhibits IL-1-induced cytokine synthesis and blocks the binding of IL-1 to its type II receptor on human monocytes. Blood 79:2356-2363
41. Granowitz EV, Vannier E, Poutsiaka DD, Dinarello CA 1992 Effect of interleukin-1 (IL-1) blockade on cytokine synthesis: II. IL-1 receptor antagonist inhibits lipop olysaccha ride-induced cytokine synthesis by human monocytes. Blood 79:2364-2369
42. Hirsch E, Irikura VM, Paul SM, Hirsh D 1996 Functions of interleukin 1 receptor antagonist in gene knockout and overproducing mice. Proc Natl Acad Sci USA 93:11008-11013
43. Cohen PE, Pollard JW 1998 Normal sexual function in male mice lacking a functional type I interleukin-1 (IL-1) receptor. Endocrinology 139:815-818
44. Parvinen M, Soder O, Mali P, Froysa B, Ritzen EM 1991 In vitro stimulation of stage-specific deoxyribonucleic acid synthesis in rat seminiferous tubule segments by interleukin-1 α. Endocrinology 129:1614-1620
45. Soder O, Syed V, Callard GV, Toppari J, Pollanen P, Parvinen M, Froysa B, Ritzen EM 1991 Production and secretion of an interleukin-1-like factor is stage-dependent and correlates with spermatogonial DNA synthesis in the rat seminiferous epithelium, lnt J Androl 14:223-231
46. Sultana T, Svechnikov K, Weber G, Soder O 2000 Molecular cloning and expression of a functionally different alternative splice variant of prointerleukin-la from the rattestis. Endocrinology 141:4413-4418
47. Naz RK, Kaplan P 1994 Interleukin-6 enhances the fertilization capacity of human sperm increasing capacitation and acrosome reaction, J Androl 15: 228-233
48. Fedder J, Ellerman-Eriksen S 1995 Effect of cytokines on sperm motility and ionophore-stimulated acrosome reaction. Arch Androl 35:173-185
49. Sikka SC, Champion HC, Bivalacqua, TJ, Estrada IS, Wang R, Rajasekaran M, Aggarwal BB, Hellstrom WJ 2001 Role of genitourinary inflammation in infertility: synergistic effect of lipopolysaccharide and interferone-γ on human spermatozoa. In J Androl 241:136-141
50. Estrada LS, Champion HC, Wang R, Rajasekaran M, Hellstrom WJ, Aggarwal B, Sikka SC 1997 Effect of tumour necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) on human sperm motility, viability and motion parameters. lnt J Androl 20:237-242
51. Faber BM, Chegini N, Mahony MC, Coddington III CC 2001 Macrophages secretory products and sperm zona pellucida binding. Obstet Gynecol 98: 668-673
52. Sueldo CE, Kelly E, Subias, Baccaro M, Swanson JA, Steinleitner A, Lambert H 1990 Effect of interleukin-1 on gamete interaction and mouse embryo development. J Reprod Med 35:868-872
53. Hill JA, Cohen J, Anderson DJ 1998 The effects of lymphokines and monokines on human sperm fertilizing ability in the zona-free hamster egg penetration test. Am J Obstet Gynecol 160:1154-1159
54. de los Santos MJ, Anderson DJ, Racowsky C, Simon C, Hill JA 1995 Expression of interleukin-1 system genes in human gametes. Biol Reprod 59:1419-1424
55. Naz RK, Sellamuthu R 2006 Receptors in spermatozoa: are they real? J Androl 27:627-636
56. Hullstrom WJ, Schachter J, Sweet RL, McClure RD 1987 Is there a role for Chlamydid trdch omdtis and genital mycoplasrna in male infertility? Fertil Steril 48:337-339
57. Hales DB, Diemer T, Hales KH 1999 Role of cytokines in testicular function. Endocrinology 10:201-217
58. Berger RE, Karp LE, Williamson RA, Kochler J, Moore DE, Holmes KK 1982 The relationship of pyospermia and seminal fluid bacteriology to sperm function as reflected in the sperm penetration assay. Fertil Steril 37:557-564
59. Maruyama DK, Hale RW, Rogers BJ 1985 Effects of white blood cells on the in vitro penetration of zona-free hamster eggs by human spermatozoa. J Androl 6:127-135
60. Keck C, Gerber-Schafer C, Clad A, Wilhelm C, Breckwoldt M 1998 Seminal tract infections: impact on male fertility and treatment options. Hum Reprod Update 4:891-903
61. Hill JA, Haimovici F, Politch JA, Anderson DJ 1987 Effects of soluble products of activated lymphocytes and macrophages (lymphokines and monokines) on human sperm motion parameters. Fertil Steril 47:460-465
62. Comhaire FH, Mahmoud AM, Depuydt CE, Zalata AA, Christopher AB 1999 Mechanisms and effects of male genital infection on sperm quality and fertilizing potential: the andrologist's viewpoint. Hum Reprod Update 5:393-398
63. Rajasekaran M, Hellstrom WJ, Naz RK, Sikka SC 1995 Oxidative stress and interleukins in seminal plasma during leukocytospermia. Fertil Steril 64:166-171
64. Rajasekaran M, Hellstrom WJ, Sikka SC 1996 Quantitative assessment of cytokines (GRO α and IL-10) in human seminal plasma during genitourinary inflammation. Am J Reprod Immunol 36:90-95
65. Huleihel M, Lunenfeld E, Levy A, Potashnik G, Glezerman M 1996 Distinct expression levels of cytokines and soluble cytokine receptors in seminal plasma of human fertile and infertile males. Fertil Steril 66:135-139
66. Hussenet F, Dousset B, Cordonnier JL, Jacob C, Foliguet B, Grignon G, Nabet P 1993 Tumour necrosis factor α and interleukin 2 in normal and infected human seminal fluid. Hum Reprod 8:409-411
67. Shimoya K, Matsuzaki N, Tsutsui T, Taniguchi T, Saji F, Tanizawa O 1993 Detection of interleukin-8 (1L-8) in seminal plasma and elevated IL-8 in seminal plasma of infertile patients with leukospermia. Fertil Steril 59:885-888