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Volumn 83, Issue 1, 2009, Pages 87-94

Metallothionein attenuates carmustine-induced oxidative stress and protects against pulmonary fibrosis in rats

Author keywords

Glutathione; Glutathione reductase; Metallothionein; Oxidative stress; Pulmonary fibrosis; TNF

Indexed keywords

ALCOHOL; CARMUSTINE; COLLAGEN; GLUTATHIONE REDUCTASE; HYDROXYPROLINE; METALLOTHIONEIN; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA;

EID: 58149475489     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-008-0325-7     Document Type: Article
Times cited : (37)

References (38)
  • 1
    • 0036070549 scopus 로고    scopus 로고
    • Oxidative stress and inflammation contribute to lung toxicity after a common breast cancer chemotherapy regimen
    • 2
    • AM Abushamaa TA Sporn RJ Folz 2002 Oxidative stress and inflammation contribute to lung toxicity after a common breast cancer chemotherapy regimen Am J Physiol Lung Cell Mol Physiol 283 2 L336 L345
    • (2002) Am J Physiol Lung Cell Mol Physiol , vol.283
    • Abushamaa, A.M.1    Sporn, T.A.2    Folz, R.J.3
  • 2
    • 0034671886 scopus 로고    scopus 로고
    • Metallothionein inhibits peroxynitrite-induced DNA and lipoprotein damage
    • 50
    • L Cai JB Klein YJ Kang 2000 Metallothionein inhibits peroxynitrite- induced DNA and lipoprotein damage J Biol Chem 275 50 38957 38960
    • (2000) J Biol Chem , vol.275 , pp. 38957-38960
    • Cai, L.1    Klein, J.B.2    Kang, Y.J.3
  • 3
    • 0016808562 scopus 로고
    • Purification and characterization of the flavoenzyme glutathione reductase from rat liver
    • I Carlberg B Mannervik 1975 Purification and characterization of the flavoenzyme glutathione reductase from rat liver J Biol Chem 14 5475 5480
    • (1975) J Biol Chem , vol.14 , pp. 5475-5480
    • Carlberg, I.1    Mannervik, B.2
  • 4
    • 0028789569 scopus 로고
    • Metallothionein induction in cultured rat hepatocytes by arthritic rat serum, activated macrophages, interleukin-6, interleukin-1 and leukaemia inhibitory factor
    • P Coyle JC Philcox AM Rofe 1995 Metallothionein induction in cultured rat hepatocytes by arthritic rat serum, activated macrophages, interleukin-6, interleukin-1 and leukaemia inhibitory factor Inflamm Res 44 475 481
    • (1995) Inflamm Res , vol.44 , pp. 475-481
    • Coyle, P.1    Philcox, J.C.2    Rofe, A.M.3
  • 5
    • 0029858934 scopus 로고    scopus 로고
    • Metallothionein is a component of exocrine pancreas secretion: Implications for zinc homeostasis
    • RC De Lisle MP Sarras Jr J Hidalgo GK Andrews 1996 Metallothionein is a component of exocrine pancreas secretion: implications for zinc homeostasis Am J Physiol 271 C1103 C1110
    • (1996) Am J Physiol , vol.271
    • De Lisle, R.C.1    Sarras Jr, M.P.2    Hidalgo, J.3    Andrews, G.K.4
  • 6
    • 3042934967 scopus 로고
    • Tissue sulfhydryl groups
    • GL Ellman 1959 Tissue sulfhydryl groups Arch Biochem Biophys 82 70 77
    • (1959) Arch Biochem Biophys , vol.82 , pp. 70-77
    • Ellman, G.L.1
  • 7
    • 0034431511 scopus 로고    scopus 로고
    • Glutathione depletion is associated with augmenting a proinflammatory signal: Evidence for an antioxidant/pro-oxidant mechanism regulating cytokines in the alveolar epithelium
    • 4
    • JJ Haddad 2000 Glutathione depletion is associated with augmenting a proinflammatory signal: evidence for an antioxidant/pro-oxidant mechanism regulating cytokines in the alveolar epithelium Cytokines Cell Mol Ther 6 4 177 187
    • (2000) Cytokines Cell Mol Ther , vol.6 , pp. 177-187
    • Haddad, J.J.1
  • 8
    • 0036384284 scopus 로고    scopus 로고
    • Redox regulation of pro-inflammatory cytokines and IkappaB-alpha/NF-kappa B nuclear translocation and activation
    • 4
    • JJ Haddad 2002 Redox regulation of pro-inflammatory cytokines and IkappaB-alpha/NF-kappa B nuclear translocation and activation Biochem Biophys Res Commun 296 4 847 856
    • (2002) Biochem Biophys Res Commun , vol.296 , pp. 847-856
    • Haddad, J.J.1
  • 9
    • 0035126833 scopus 로고    scopus 로고
    • Thiol regulation of pro-inflammatory cytokines reveals a novel immunopharmacological potential of glutathione in the alveolar epithelium
    • 3
    • JJ Haddad B Safieh-Garabedian NE Saadé SC Land 2001 Thiol regulation of pro-inflammatory cytokines reveals a novel immunopharmacological potential of glutathione in the alveolar epithelium J Pharmacol Exp Ther 296 3 996 1005
    • (2001) J Pharmacol Exp Ther , vol.296 , pp. 996-1005
    • Haddad, J.J.1    Safieh-Garabedian, B.2    Saadé, N.E.3    Land, S.C.4
  • 10
    • 0345280793 scopus 로고    scopus 로고
    • Metallothionein induction attenuates the effects of glutathione depletors in rat hepatocytes
    • 2
    • K Haïdara P Moffatt F Denizeau 1999 Metallothionein induction attenuates the effects of glutathione depletors in rat hepatocytes Toxicol Sci 49 2 297 305
    • (1999) Toxicol Sci , vol.49 , pp. 297-305
    • Haïdara, K.1    Moffatt, P.2    Denizeau, F.3
  • 11
    • 0022555879 scopus 로고
    • Metallothionein
    • DH Hamer 1986 Metallothionein Annu Rev Biochem 55 913 951
    • (1986) Annu Rev Biochem , vol.55 , pp. 913-951
    • Hamer, D.H.1
  • 13
    • 0030909324 scopus 로고    scopus 로고
    • Elevated serum tumor necrosis factor-alpha levels in patients with systemic sclerosis: Association with pulmonary fibrosis
    • M Hasegawa M Fujimotom K Kikuchi K Takehara 1997 Elevated serum tumor necrosis factor-alpha levels in patients with systemic sclerosis: association with pulmonary fibrosis J Rheumatol 24 663 665
    • (1997) J Rheumatol , vol.24 , pp. 663-665
    • Hasegawa, M.1    Fujimotom, M.2    Kikuchi, K.3    Takehara, K.4
  • 15
    • 20444431515 scopus 로고    scopus 로고
    • Effects of exogenous metallothionein on acute cadmium toxicity in rats
    • 3
    • H Kara F Karatas H Canatan K Servi 2005 Effects of exogenous metallothionein on acute cadmium toxicity in rats Biol Trace Elem Res 104 3 223 232
    • (2005) Biol Trace Elem Res , vol.104 , pp. 223-232
    • Kara, H.1    Karatas, F.2    Canatan, H.3    Servi, K.4
  • 16
    • 0020608442 scopus 로고
    • The effect of BCNU (carmustine) on tissue glutathione reductase activity
    • 1-2
    • JP Kehrer 1983 The effect of BCNU (carmustine) on tissue glutathione reductase activity Toxicol Lett 17 1-2 63 68
    • (1983) Toxicol Lett , vol.17 , pp. 63-68
    • Kehrer, J.P.1
  • 17
    • 0022396809 scopus 로고
    • Enhanced acute lung damage in mice following administration of 1, 3-bis (2-chloroethyl)-1-nitrosourea
    • 11 Pt 2
    • JP Kehrer AJ Klein-Szanto 1985 Enhanced acute lung damage in mice following administration of 1, 3-bis (2-chloroethyl)-1-nitrosourea Cancer Res 45 11 Pt 2 5707 5713
    • (1985) Cancer Res , vol.45 , pp. 5707-5713
    • Kehrer, J.P.1    Klein-Szanto, A.J.2
  • 18
    • 16644384082 scopus 로고    scopus 로고
    • Modeling the function of tumor necrosis factor in immune pathophysiology
    • Suppl 1
    • G Kollias 2004 Modeling the function of tumor necrosis factor in immune pathophysiology Autoimmun Rev 3 Suppl 1 S24 S25
    • (2004) Autoimmun Rev , vol.3
    • Kollias, G.1
  • 19
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor super families: Integrating mammalian biology
    • RM Locksley N Killeen MJ Lenardo 2001 The TNF and TNF receptor super families: integrating mammalian biology Cell 104 487 501
    • (2001) Cell , vol.104 , pp. 487-501
    • Locksley, R.M.1    Killeen, N.2    Lenardo, M.J.3
  • 22
    • 0030632095 scopus 로고    scopus 로고
    • Antioxidant activity of metallothionein compared with reduced glutathione
    • T Miura S Muraoka T Ogiso 1997 Antioxidant activity of metallothionein compared with reduced glutathione Life Sci 60 301 309
    • (1997) Life Sci , vol.60 , pp. 301-309
    • Miura, T.1    Muraoka, S.2    Ogiso, T.3
  • 24
    • 0034602705 scopus 로고    scopus 로고
    • Role of metallothionein in nitric oxide signaling as revealed by a green fluorescent fusion protein
    • LL Pearce RE Gandley W Han 2000 Role of metallothionein in nitric oxide signaling as revealed by a green fluorescent fusion protein Proc Natl Acad Sci USA 97 477 482
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 477-482
    • Pearce, L.L.1    Gandley, R.E.2    Han, W.3
  • 25
    • 0034952985 scopus 로고    scopus 로고
    • Metallothionein treatment reduces proinflammatory cytokines IL-6 and TNF-alpha and apoptotic cell death during experimental autoimmune encephalomyelitis (EAE)
    • 1
    • M Penkowa J Hidalgo 2001 Metallothionein treatment reduces proinflammatory cytokines IL-6 and TNF-alpha and apoptotic cell death during experimental autoimmune encephalomyelitis (EAE) Exp Neurol 170 1 1 14
    • (2001) Exp Neurol , vol.170 , pp. 1-14
    • Penkowa, M.1    Hidalgo, J.2
  • 26
    • 0025211892 scopus 로고
    • Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis
    • PF Piguet MA Collart GE Grau AP Sappino P Vassalli 1990 Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis Nature 344 245 247
    • (1990) Nature , vol.344 , pp. 245-247
    • Piguet, P.F.1    Collart, M.A.2    Grau, G.E.3    Sappino, A.P.4    Vassalli, P.5
  • 27
    • 0029881336 scopus 로고    scopus 로고
    • Simplified method for the analysis of hydroxyproline in biological tissues
    • 3
    • GK Reddy CS Enwemeka 1996 Simplified method for the analysis of hydroxyproline in biological tissues Clin Biochem 29 3 225 229
    • (1996) Clin Biochem , vol.29 , pp. 225-229
    • Reddy, G.K.1    Enwemeka, C.S.2
  • 28
    • 0027533507 scopus 로고
    • Oxygen free radicals and metallothionein
    • M Sato I Bremner 1993 Oxygen free radicals and metallothionein Free Radic Biol Med 14 325 337
    • (1993) Free Radic Biol Med , vol.14 , pp. 325-337
    • Sato, M.1    Bremner, I.2
  • 30
    • 0021238361 scopus 로고
    • Preferential effects of 1, 3-bis (2-chloroethyl)-1-nitrosourea (BCNU) on pulmonary glutathione reductase and glutathione/glutathione disulfide ratios: Possible implications for lung toxicity
    • AC Smith MR Boyd 1984 Preferential effects of 1, 3-bis (2-chloroethyl)-1-nitrosourea (BCNU) on pulmonary glutathione reductase and glutathione/glutathione disulfide ratios: possible implications for lung toxicity J Pharmacol Exp Ther 229 658 663
    • (1984) J Pharmacol Exp Ther , vol.229 , pp. 658-663
    • Smith, A.C.1    Boyd, M.R.2
  • 31
    • 0021944046 scopus 로고
    • Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals
    • PJ Thornalley M Vasak 1985 Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals Biochim Biophys Acta 827 36 44
    • (1985) Biochim Biophys Acta , vol.827 , pp. 36-44
    • Thornalley, P.J.1    Vasak, M.2
  • 32
    • 0017078048 scopus 로고
    • Clinical studies in malignant gliomas and their treatment with the nitrosoureas
    • MD Walker EA Gehan 1976 Clinical studies in malignant gliomas and their treatment with the nitrosoureas Cancer Treat Rep 60 713 718
    • (1976) Cancer Treat Rep , vol.60 , pp. 713-718
    • Walker, M.D.1    Gehan, E.A.2
  • 35
    • 0035015920 scopus 로고    scopus 로고
    • Reduction of BCNU toxicity to lung cells by high-level expression of O(6)-methylguanine-DNA methyltransferase
    • 4
    • M Wu MR Kelley WK Hansen WJ Martin 2001 Reduction of BCNU toxicity to lung cells by high-level expression of O(6)-methylguanine-DNA methyltransferase Am J Physiol Lung Cell Mol Physiol 280 4 L755 L761
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.280
    • Wu, M.1    Kelley, M.R.2    Hansen, W.K.3    Martin, W.J.4
  • 36
    • 34047147323 scopus 로고    scopus 로고
    • Metallothionein in bladder cancer: Correlation of overexpression with poor outcome after chemotherapy
    • 2
    • C Wülfing H van Ahlen E Eltze H Piechota L Hertle KW Schmid 2007 Metallothionein in bladder cancer: correlation of overexpression with poor outcome after chemotherapy World J Urol 25 2 199 205
    • (2007) World J Urol , vol.25 , pp. 199-205
    • Wülfing, C.1    Van Ahlen, H.2    Eltze, E.3    Piechota, H.4    Hertle, L.5    Schmid, K.W.6
  • 37
    • 0033402179 scopus 로고    scopus 로고
    • Metallothionein induced suppression of cytotoxic T lymphocyte function: An important immunoregulatory control
    • 2
    • J Youn MA Lynes 1999 Metallothionein induced suppression of cytotoxic T lymphocyte function: an important immunoregulatory control Toxicol Sci 52 2 199 208
    • (1999) Toxicol Sci , vol.52 , pp. 199-208
    • Youn, J.1    Lynes, M.A.2
  • 38
    • 0036379353 scopus 로고    scopus 로고
    • Metallothionein suppresses collagen-induced arthritis via induction of TGF-β and down-regulation of proinflammatory mediators
    • 2
    • J Youn SH Hwang ZY Ryoo MA Lynes DJ Paik HS Chung HY Kim 2002 Metallothionein suppresses collagen-induced arthritis via induction of TGF-β and down-regulation of proinflammatory mediators Clin Exp Immunol 129 2 232 239
    • (2002) Clin Exp Immunol , vol.129 , pp. 232-239
    • Youn, J.1    Hwang, S.H.2    Ryoo, Z.Y.3    Lynes, M.A.4    Paik, D.J.5    Chung, H.S.6    Kim, H.Y.7


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