Isotype and IgG subclass distribution of autoantibody response to alpha-enolase protein in adult patients with severe Asthma

Yonsei Medical Journal

Volumn 49, Issue 6, 2008, Pages 923-930

  Lee, Hye Ah ^a   Kwon, Byul ^a   Hur, Gyu Young ^a   Choi, Sung Jin ^a   Nahm, Dong Ho ^a   Park, Hae Sim ^a  

^a Ajou University School of Medicine   (South Korea)

Author keywords

Asthma; Autoantibody; IgE; IgG; IgG subclass

Indexed keywords

ALPHA ENOLASE; AUTOANTIBODY; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G4; IMMUNOGLOBULIN M;

ADULT; AGED; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; ASTHMA; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HUMAN; IMMUNOBLOTTING; MALE; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; PROTEIN PURIFICATION;

ADULT; AGED; ASTHMA; AUTOANTIBODIES; AUTOANTIGENS; CASE-CONTROL STUDIES; COMPLEMENT ACTIVATION; FEMALE; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN ISOTYPES; MALE; MIDDLE AGED; PHOSPHOPYRUVATE HYDRATASE; RECOMBINANT PROTEINS; YOUNG ADULT;

EID: 58149470824     PISSN: 05135796     EISSN: None     Source Type: Journal    
DOI: 10.3349/ymj.2008.49.6.923     Document Type: Article

References (26)

1. Mechanisms of asthma. Global Initiative for Asthma: Global strategy for asthma management and prevention. Bethesda, Md., National Institutes of Health (NIH publication no. 02-3659). 2002. p.50-66.
2. The ENFUMOSA study group. The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma. Eur Respir J 2003; 22:470-7.
3. Busse WW, Banks-Schlegel S, Wenzel SE. Pathophysiology of severe asthma. J Allergy Clin Immunol 2000;106: 1033-42.
4. Rottem M, Shoenfeld Y. Asthma as a paradigm for autoimmune disease. Int Arch Allergy Immunol 2003;132: 210-4.
5. Virchow JC Jr, Kroegel C, Walker C, Matthys H. Inflammatory determinants of asthma severity: mediator and cellular changes in bronchoalveolar lavage fluid of patients with severe asthma. J Allergy Clin Immunol 1996;98:S27-33; discussion S33-40.
6. Wagner V, Tomsikova A, Sach J, Jankova J, Novackova D. Autoimmune mechanism in diseases of the respiratory tract. Acta Allergol 1965;20:1-9.
7. Nahm DH, Lee YE, Yim EJ, Park HS, Yim H, Kang Y et al. Identification of cytokeratin 18 as a bronchial epithelial autoantigen associated with nonallergic asthma. Am J Respir Crit Care Med 2002;165:1536-9.
8. Lassalle P, Delneste Y, Gosset P, Gras-Masse H, Wallaert B, Tonnel AB. T and B cell immune response to a 55-kDa endothelial cell-derived antigen in severe asthma. Eur J Immunol 1993;23:796-803.
9. Dekker JW, Nizankowska E, Schmitz-Schumann M, Pile K, Bochenek G, Dyczek A, et al. Aspirin-induced asthma and HLA-DRB1 and HLA-DPB1 genotypes. Clin Exp Allergy 1997;27:574-7.
10. Kero J, Gissler M, Hemminki E, Isolauri E. Could TH1 and TH2 diseases coexist? Evaluation of asthma incidence in children with coeliac disease, type 1 diabetes, or rheumatoid arthritis: a register study. J Allergy Clin Immunol 2001;108:781-3.
11. Holgate ST. Cytokine and anti-cytokine therapy for the treatment of asthma and allergic disease. Cytokine 2004;28:152-7.
12. Kon OM, Kay AB. Anti-T cell strategies in asthma. Inflamm Res 1999;48:516-23.
13. Nahm DH, Lee KH, Shin JY, Ye YM, Kang Y, Park HS. Identification of alpha-enolase as an autoantigen associated with severe asthma. J Allergy Clin Immunol 2006;118:376-81.
14. Lee KH, Chung HS, Kim HS, Oh SH, Ha MK, Baik JH, et al. Human alpha-enolase from endothelial cells as a target antigen of anti-endothelial cell antibody in Beh&et's disease. Arthritis Rheum 2003;48:2025-35.
15. Nahm DH, Park HS. Analysis of induced sputum for studying allergen-specific IgE antibodies in airway secretion from asthmatic patients. Clin Exp Allergy 1998;28:686-93.
16. Paul S, Said SI, Thompson AB, Volle DJ, Agrawal DK, Foda H, et al. Characterization of autoantibodies to vasoactive intestinal peptide in asthma. J Neuroimmunol 1989;23:133-42.
17. Terrier B, Degand N, Guilpain P, Servettaz A, Guillevin L, Mouthon L. Alpha-enolase: a target of antibodies in infectious and autoimmune diseases. Autoimmun Rev 2007;6:176-82.
18. Girard JP, Dami J. Antigenic properties of lung tissue. Presence of specific antibodies in certain chronic respiratory disorders. Poumon Coeur 1973;29:267-70.
19. Szczeklik A, Nizankowska E, Serafin A, Dyczek A, Duplaga M, Musial J. Autoimmune phenomena in bronchial asthma with special reference to aspirin intolerance. Am J Respir Crit Care Med 1995;152:1753-6.
20. Lee SH, Rhim T, Choi YS, Min JW, Kim SH, Cho SY, et al. Complement C3a and C4a increased in plasma of patients with aspirin-induced asthma. Am J Respir Crit Care Med 2006;173:370-8.
21. Wills-Karp M, Koehl J. New insights into the role of the complement pathway in allergy and asthma. Curr Allergy Asthma Rep 2005;5:362-9.
22. Callerame ML, Condemi JJ, Bohrod MG, Vaughan JH. Immunologic reactions of bronchial tissues in asthma. N Engl J Med 1971;284:459-64.
23. Fregonese L, Swan FJ, van Schadewijk A, Dolhnikoff M, Santos MA, Daha MR, et al. Expression of the anaphylatoxin receptors C3aR and C5aR is increased in fatal asthma. J Allergy Clin Immunol 2005;115:1148-54.
24. Wakui H, Imai H, Komatsuda A, Miura AB. Circulating antibodies against alpha-enolase in patients with primary membranous nephropathy (MN). Clin Exp Immunol 1999;118:445-50.
25. Holdsworth SR, Kitching AR, Tipping PG. Th1 and Th2 T helper cell subsets affect patterns of injury and outcomes in glomerulonephritis. Kidney Int 1999;55:1198-216.
26. Jenmalm MC, Björkstén B, Macaubas C, Holt BJ, Smallacombe TB, Holt PG. Allergen-induced cytokine secretion in relation to atopic symptoms and immunoglobulin E and immunoglobulin G subclass antibody responses. Pediatr Allergy Immunol 1999;10:168-77.