Formulation, characterization and evaluation of rotavirus encapsulated PLA and PLGA particles for oral vaccination

Journal of Microencapsulation

Volumn 26, Issue 2, 2009, Pages 154-165

  Nayak, Bismita ^a,b   Panda, Amulya K ^c   Ray, Pratima ^b   Ray, Alok R ^a,b  

^a INDIAN INSTITUTE OF TECHNOLOGY DELHI   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^c NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

Author keywords

Biodegradable polymers; IgA and IgG antibody titer; Immune response; Microparticle; Rotavirus

Indexed keywords

BICARBONATE; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; NANOPARTICLE; POLYGLACTIN; POLYLACTIDE; ROTAVIRUS VACCINE; SERUM ALBUMIN; SUCROSE;

ANIMAL EXPERIMENT; ANTIBODY TITER; ARTICLE; ATOMIC FORCE MICROSCOPY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG STABILITY; DRUG STRUCTURE; EMULSION; ENCAPSULATION; MOUSE; NONHUMAN; PARTICLE SIZE; ROTAVIRUS; SCANNING ELECTRON MICROSCOPY; SINGLE DRUG DOSE; SURFACE PROPERTY; ULTRASOUND;

ADMINISTRATION, ORAL; ANIMALS; CATTLE; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; CIRCULAR DICHROISM; DRUG COMPOUNDING; LACTIC ACID; PARTICLE SIZE; POLYGLYCOLIC ACID; POLYMERS; ROTAVIRUS; SERUM ALBUMIN, BOVINE; VACCINATION; VACCINES;

EID: 58149465364     PISSN: 02652048     EISSN: 14645246     Source Type: Journal    
DOI: 10.1080/02652040802211709     Document Type: Article

References (40)

1. Angel, J., Franco, MA and Greenberg, HB (2007) Rotavirus vaccines: Recent developments and future considereations. Nat Rev Mocrobiol, 5, pp. 527-539.
2. Arias, CF, Dector, MA, Segovia, L., Lopez, T., Camacho, M., Isa, P., Espinosa, R. and Lopez, S. (2004) RNA silencing of rotavirus gene expression. Virus Res, 102, pp. 43-51.
3. Bhandari, N., Sharma, P., Glass, RI, Ray, P., Greenberg, H., Taneja, S., Saksena, M., Rao, CD, Gentsch, JR Parashar, U. et al. (2006) Safety and immunogenicity of two live attenuated human rotavirus vaccine candidates, 116E and I321, in infants: Results of a randomised controlled trial. Vaccine, 24, pp. 5817-5823.
4. Brayden, DJ and Baird, AW (2001) Microparticle vaccine approaches to stimulate mucosal immunization. Microbes Infect, 3, pp. 867-876.
5. Charles, MD, Holman, RC, Curns, AT, Parashar, U., Glass, R. and Bresee, J. (2006) Hospitalizations associated with rotavirus gastroenteritis in the united states 1993-2002. J Pediar Infect Dis, 25, pp. 489-493.
6. Chen, SC, Jones, DH and Fynan, EF (1998) Protective immunity induces by oral immunization with a rotavirus DNA vaccine encapsulated in microparticles. J Virol, 72, pp. 5757-5761.
7. Duncan, JD, Wang, PX, Harrington, CM, Schafer, DP, Matsuoka, Y., Mestecky, JF, Compans, RW and Novak, MJ (1996) Comparative analysis of oral delivery systems for live rotavirus vaccines. J Contr Rel, 3, pp. 237-247.
8. Eldridge, JH, Gilley, RM, Moldeveaunu, Z., Stass, JK, Meulbroek, JA and Tice, TR (1989) Biodegradable microspheres: Vaccine delivery system for oral immunization. Curr Top Microbiol Immunol, 146, pp. 59-66.
9. Eldridge, JH, Hammond, CJ, Meulbroek, JA, Stass, JK, Gilley, RM and Tice, TR (1990) Controlled vaccine release in the gut-associated lymphoid tissues. I. Orally administered biodegradable microspheres target the peyer's patches. J Contr Rel, 11, pp. 205-214.
10. Estes, MK, Kang, G., Zeng, CQ, Crawford, SE and Ciarlet, M. (2001) Pathogenesis of rotavirus gastroenteritis. Novartis Found Symp, 238, pp. 82-96.
11. Eldrige, JH, Stass, JK, Meulbroek, JA, Tice, TR and Gilley, RM (1991) Biodegradable and biocompatible poly(DL-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid which enhances the level of toxin-neutralizing antibodies. Infect Immun, 59, pp. 2978-2986.
12. Franco, MA, Angel, J. and Greenberg, HB (2006) Immunity and correlates of protection for rotavirus vaccines. Vaccine, 24, pp. 2718-2731.
13. Glass, RI, Gentsch, JR and Ivanoff, B. (1996) New lessons for Rotavirus vaccines. Science, 272, pp. 46-48.
14. Glass, RI, Parashar, UD, Bresee, JS, Turcios, R., Fischer, TK, Widdowson, MA, Jiang, B. and Gentsch, JR (2006) Rotavirus vaccines: Current prospects and future challenges. Lancet, 368, pp. 323-332.
15. Gutierro, I., Hernandez, RM, Igartua, M., Gascon, AR and Pedraz, JL (2002) Size dependent immune response after subcutaneous, oral and intranasal administration of BSA loaded nanospheres. Vaccine, 21, pp. 67-77.
16. O'Hagan, DT, Jeffery, H., Roberts, MJ, Mc Gee, JP and Davis, SS (1991) Controlled release microparticles for vaccine development. Vaccine, 9, pp. 768-771.
17. O'Hagan, DT, Singh, M. and Gupta, RK (1998) Poly (lactide-co-glycolide) microparticles for the development of single dose controlled release vaccines. Adv Drug Deliv Rev, 32, pp. 225-246.
18. Jeffery, LC (1999) Single-administration vaccines: C-release technology to mimic repeated immunizations. Trends Biotechnol, 17, pp. 25-29.
19. Johansen, P., Gander, B., Merkle, HP and Sesardic, D. (2000) Ambiguities in the preclinical quality assessment of microparticlulate vaccines. Trends Biotechnol, 18, pp. 203-211.
20. Kanchan, V. and Panda, AK (2007) Interactions of antigen-loaded polylactide particles with macrophages and their correlation with the immune response. Biomaterials, 28, pp. 5344-5357.
21. Katare, YK, Muthukumaran, T. and Panda, AK (2005) Influence of particle size, antigen load, dose and additional adjuvant on the immune response from antigen loaded PLA microparticles. Int J Pharm, 301, pp. 149-160.
22. Katare, YK and Panda, AK (2006) Effect of excipients on physical instability, in vitro release and in vivo performances of TT loaded biodegradable polymer microparticles. Eur J Pharm Sci, 28, pp. 179-188.
23. Khoury, CA, Moser, CA, Speaker, JJ and Offit, PA (1995) Oral inoculation of mice with low doses of microencapsulated, noninfectious rotavirus induces virus-specific antibodies in gut-associated lymphoid tissue. J Contr Rel, 172, pp. 870-874.
24. Kim, B., Bowersock, T., Griebel, P., Kidane, A., Babiuk, LA, Sanchez, M., Attah-Poku, S., Kaushik, RS and Mutwiri, GK (2002) Mucosal immune responses following oral immunization with rotavirus antigens encapsulated in alginate microspheres. J Contr Rel, 85, pp. 191-202.
25. Livinghood, JR (2001) Rotavirus intussusception among infants given an oral rotavirus vaccine. N Engl J Med, 344, pp. 546-572.
26. Malek, MA, Curns, AT and Holman, RC (2006) Diarrhea and rotavirus associated hospitalizations among children less than 5 years of age: United States, 1997 and 2002. Pediatrics, 117, pp. 1887-1892.
27. McNeal, MM, Rae, MN and Ward, RL (1999) Antibody responses and protection stimulated by sequential oral-parenteral immunization of mice with rotavirus. Vaccine, 17, pp. 639-645.
28. Murphy, TV, Gargiullo, PM, Massoudi, MS, Nelson, DB, Jumaan, AO, Okoro, CA, Zanardi, LR, Setia, S., Fair, E. LeBaron, CW et al. (2001) Rotavirus intussusception among infants given an oral rotavirus vaccine. N Engl J Med, 344, pp. 546-572.
29. Offit, PA, Khoury, CA, Moser, CA, Fred Clark, H, Kim, JE and Speaker, TJ (1994) Enhancement of Rotavirus immunogenicity by microencapsulation. Virology, 203, pp. 134-143.
30. Parashar, UD, Hummelman, EG, Bresee, JS, Miller, MA and Glass, RI (2003) Global illness and deaths caused by rotavirus disease in children. Emerg Infect Dis, 9, pp. 565-572.
31. Raghuvanshi, RS, Goyal, S., Singh, OM and Panda, AK (1998) Stabilization of dichloromethane-induced protein denaturation during microencapsulation. Pharm Dev Technol, 3, pp. 269-276.
32. Raghuvanshi, RS, Singh, OM and Panda, AK (2001) Formulation and characterization of immunoreactive tetanus toxoid biodegradable polymer particles. Drug Deliv, 2, pp. 99-106.
33. Raghuvanshi, RS, Singh, OM and Panda, AK (2002) Correlation between in vitro release and in vivo immune response from biodegradable polymer particles entrapping tetanus toxoid. Drug Deliv, 9, pp. 113-120.
34. Ray, P., Malik, J., Singh, RK, Bhatnagar, S., Bahl, R., Kumar, R. and Bhan, MK (2003) Rotavirus non-structural protein NSP4 includes heterotypic antibody responses during natural infection in children. J Infect Dis, 187, pp. 1786-1793.
35. Rin, R., Ng, LS and Wang, CH (2005) In vitro study of anticancer drug doxorubicin in PLGA-based microparticles. Biomaterials, 26, pp. 4476-4485.
36. Shaobing, Z., Xianmo, D., Xiaohong, L., Wenxiang, J. and Li, L. (2004) Synthesis and characterization of biodegradable low molecular weight aliphatic polyesters and their use in protein-delivery systems. J Appl Polym Sci, 91, pp. 1848-1856.
37. Sharma, S., Ray, P., Gentsch, JR, Glass, RI, Kalra, V. and Bhan, MK (2008) Emergence of G12 rotavirus strains in Delhi, India, in 2000 to 2007. J Clin Microbiol, 46, pp. 1343-1348.
38. Srinivasan, C., Katare, YK, Muthukumaran, T. and Panda, AK (2005) Effect of additives on encapsulation efficiency, stability and bioactivity of entrapped lysozyme from biodegradable polymer particles. J Microencapsulation, 2, pp. 127-138.
39. Sturesson, C., Artursson, P., Ghaderi, R., Johansen, K., Mirazimi, A., Uhnoo, I., Syensson, L., Albertsson, AC and Carlfors, J. (1999) Encapsulation of rotavirus into poly (lactide-co-glycolide) microspheres. J Contr Rel, 59, pp. 377-389.
40. Velazquez, FR, Matson, DO, Calva, JJ, Guerrero, L., Morroul, AL and Carter-Campbell, S. (1996) Rotavirus infection in infants as protection against subsequesnt infections. N Engl J Med, 335, pp. 1022-1028.