Tiagabine increases [11C]flumazenil binding in cortical brain regions in healthy control subjects

Neuropsychopharmacology

Volumn 34, Issue 3, 2009, Pages 624-633

  Frankle, W Gordon ^a,b   Cho, Raymond Y ^a   Narendran, Rajesh ^a   Mason, N Scott ^a   Vora, Shivangi ^a   Litschge, Maralee ^a   Price, Julie C ^a   Lewis, David A ^a   Mathis, Chester A ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

band; 11C flumazenil; GABA; GABA shift; Oscillations; PET

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID CARRIER; BENZODIAZEPINE RECEPTOR; CARBON 11; FLUMAZENIL; TIAGABINE; NEUROTRANSMITTER UPTAKE INHIBITOR; NIPECOTIC ACID DERIVATIVE; SLC6A1 PROTEIN, HUMAN;

ADULT; ARTICLE; ASSOCIATION CORTEX; BRAIN CORTEX; DRUG RECEPTOR BINDING; ELECTROENCEPHALOGRAM; FEMALE; HUMAN; HUMAN EXPERIMENT; IN VIVO STUDY; LIMBIC CORTEX; MALE; NEUROTRANSMISSION; NORMAL HUMAN; OSCILLATION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SENSORY CORTEX; BLOOD; BRAIN MAPPING; COGNITION; CORTICAL SYNCHRONIZATION; DRUG ANTAGONISM; DRUG EFFECT; FEASIBILITY STUDY; METABOLISM; METHODOLOGY; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSIOLOGY; SCINTISCANNING;

ADULT; BRAIN MAPPING; CEREBRAL CORTEX; COGNITION; CORTICAL SYNCHRONIZATION; FEASIBILITY STUDIES; FEMALE; FLUMAZENIL; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GAMMA-AMINOBUTYRIC ACID; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEUROTRANSMITTER UPTAKE INHIBITORS; NIPECOTIC ACIDS; POSITRON-EMISSION TOMOGRAPHY; RECEPTORS, GABA-A;

EID: 58149461146     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/npp.2008.104     Document Type: Article

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