메뉴 건너뛰기




Volumn 10, Issue 5, 2008, Pages 410-414

Pharmacologic modulation of ACE2 expression

Author keywords

ACE2 Activity; ACE2 Protein; Eplerenone; Olmesartan; Telmisartan

Indexed keywords

ANGIOTENSIN CONVERTING ENZYME 2; ENALAPRIL; EPLERENONE; LISINOPRIL; LOSARTAN; OLMESARTAN; SPIRONOLACTONE; TELMISARTAN; VALSARTAN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN I; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR;

EID: 58149402305     PISSN: 15226417     EISSN: 15343111     Source Type: Journal    
DOI: 10.1007/s11906-008-0076-0     Document Type: Article
Times cited : (70)

References (45)
  • 1
    • 33645299090 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme II in the heart and the kidney
    • PID: 16514079, COI: 1:CAS:528:DC%2BD28Xhs1GqsL0%3D
    • Danilczyk U, Penninger JM: Angiotensin-converting enzyme II in the heart and the kidney. Circ Res 2006, 98:463–471.
    • (2006) Circ Res , vol.98 , pp. 463-471
    • Danilczyk, U.1    Penninger, J.M.2
  • 2
    • 0034721906 scopus 로고    scopus 로고
    • A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase
    • COI: 1:CAS:528:DC%2BD3cXnvVOqtbw%3D
    • Tipnis SR, Hooper NM, Hyde R, et al.: A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J Biol Chem 2000, 275:332 38–332 43.
    • (2000) J Biol Chem , vol.275 , pp. 332 38-332 43
    • Tipnis, S.R.1    Hooper, N.M.2    Hyde, R.3
  • 3
    • 0038053724 scopus 로고    scopus 로고
    • A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1–9
    • PID: 10969042, COI: 1:CAS:528:DC%2BD3MXhslOisr8%3D
    • Donoghue M, Hsieh F, Baronas E, et al.: A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1–9. Circ Res 2000, 87:E1–E9.
    • (2000) Circ Res , vol.87 , pp. E1-E9
    • Donoghue, M.1    Hsieh, F.2    Baronas, E.3
  • 4
    • 0037142101 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 is an essential regulator of heart function
    • PID: 12075344, COI: 1:CAS:528:DC%2BD38Xks1Wmurg%3D
    • Crackower MA, Sarao R, Oudit GY, et al.: Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature 2002, 417:822–828.
    • (2002) Nature , vol.417 , pp. 822-828
    • Crackower, M.A.1    Sarao, R.2    Oudit, G.Y.3
  • 5
    • 33645238126 scopus 로고    scopus 로고
    • Age-and gender-related difference of ACE2 expression in rat lung
    • PID: 16303146, COI: 1:CAS:528:DC%2BD28XivVOgsL8%3D
    • Xie X, Chen J, Wang X, et al.: Age-and gender-related difference of ACE2 expression in rat lung. Life Sci 2006, 78:2166–2171.
    • (2006) Life Sci , vol.78 , pp. 2166-2171
    • Xie, X.1    Chen, J.2    Wang, X.3
  • 6
    • 28844487526 scopus 로고    scopus 로고
    • Distribution of angiotensin-(1–7) and ACE2 in human placentas of normal and pathological pregnancies
    • PID: 16338465, COI: 1:CAS:528:DC%2BD2MXhtlags7%2FI
    • Valdes G, Neves LA, Anton L, et al.: Distribution of angiotensin-(1–7) and ACE2 in human placentas of normal and pathological pregnancies. Placenta 2006, 27:200–207.
    • (2006) Placenta , vol.27 , pp. 200-207
    • Valdes, G.1    Neves, L.A.2    Anton, L.3
  • 7
    • 28144453548 scopus 로고    scopus 로고
    • Chronic liver injury in rats and humans upregulates the novel enzyme angiotensin converting enzyme 2
    • PID: 16166274, COI: 1:CAS:528:DC%2BD2MXhtlWkur7J
    • Paizis G, Tikellis C, Cooper ME, et al.: Chronic liver injury in rats and humans upregulates the novel enzyme angiotensin converting enzyme 2. Gut 2005, 54:1790–1796.
    • (2005) Gut , vol.54 , pp. 1790-1796
    • Paizis, G.1    Tikellis, C.2    Cooper, M.E.3
  • 8
    • 21844460785 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 protects from severe acute lung failure
    • PID: 16001071, COI: 1:CAS:528:DC%2BD2MXlvVGiu7Y%3D
    • Imai Y, Kuba K, Rao S, et al.: Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature 2005, 436:112–116.
    • (2005) Nature , vol.436 , pp. 112-116
    • Imai, Y.1    Kuba, K.2    Rao, S.3
  • 9
    • 2642539225 scopus 로고    scopus 로고
    • Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis
    • PID: 15141377, COI: 1:CAS:528:DC%2BD2cXlsVWktbY%3D
    • Hamming I, Timens W, Bulthuis ML, et al.: Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis. J Pathol 2004, 203:631–637.
    • (2004) J Pathol , vol.203 , pp. 631-637
    • Hamming, I.1    Timens, W.2    Bulthuis, M.L.3
  • 10
    • 33846183617 scopus 로고    scopus 로고
    • Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system
    • PID: 16946085, COI: 1:CAS:528:DC%2BD2sXisFGiu7k%3D
    • Doobay MF, Talman LS, Obr TD, et al.: Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system. Am J Physiol Regul Integr Comp Physiol 2007, 292:R373–R381.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.292 , pp. R373-R381
    • Doobay, M.F.1    Talman, L.S.2    Obr, T.D.3
  • 11
    • 42149131482 scopus 로고    scopus 로고
    • New aspects of the renin-angiotensin system: angiotensin-converting enzyme 2—a potential target for treatment of hypertension and diabetic nephropathy
    • PID: 18408475, COI: 1:CAS:528:DC%2BD1cXlsFSgu7k%3D
    • Batlle D, Soler MJ, Wysocki J: New aspects of the renin-angiotensin system: angiotensin-converting enzyme 2—a potential target for treatment of hypertension and diabetic nephropathy. Curr Opin Nephrol Hypertens 2008, 17:250–257.
    • (2008) Curr Opin Nephrol Hypertens , vol.17 , pp. 250-257
    • Batlle, D.1    Soler, M.J.2    Wysocki, J.3
  • 12
    • 42649108710 scopus 로고    scopus 로고
    • ACE2 and the kidney
    • PID: 18223023, COI: 1:CAS:528:DC%2BD1cXnvFCht7w%3D
    • Soler MJ, Wysocki J, Batlle D: ACE2 and the kidney. Exp Physiol 2008, 93:549–553.
    • (2008) Exp Physiol , vol.93 , pp. 549-553
    • Soler, M.J.1    Wysocki, J.2    Batlle, D.3
  • 13
    • 34548153521 scopus 로고    scopus 로고
    • ACE2 inhibition worsens glomerular injury in association with increased ACE expression in streptozotocin-induced diabetic mice
    • PID: 17579661, COI: 1:CAS:528:DC%2BD2sXpsVart7w%3D
    • Soler MJ, Wysocki J, Ye M, et al.: ACE2 inhibition worsens glomerular injury in association with increased ACE expression in streptozotocin-induced diabetic mice. Kidney Int 2007, 72:614–623.
    • (2007) Kidney Int , vol.72 , pp. 614-623
    • Soler, M.J.1    Wysocki, J.2    Ye, M.3
  • 14
    • 33745725913 scopus 로고    scopus 로고
    • Developmental expression of ACE2 in the SHR kidney: a role in hypertension?
    • PID: 16710353, COI: 1:CAS:528:DC%2BD28XmtlGltrs%3D
    • Tikellis C, Cooper ME, Bialkowski K, et al.: Developmental expression of ACE2 in the SHR kidney: a role in hypertension? Kidney Int 2006, 70:34–41.
    • (2006) Kidney Int , vol.70 , pp. 34-41
    • Tikellis, C.1    Cooper, M.E.2    Bialkowski, K.3
  • 15
    • 33747052918 scopus 로고    scopus 로고
    • ACE and ACE2 activity in diabetic mice
    • PID: 16804085, COI: 1:CAS:528:DC%2BD28XmvVChtb0%3D
    • Wysocki J, Ye M, Soler MJ, et al.: ACE and ACE2 activity in diabetic mice. Diabetes 2006, 55:2132–2139.
    • (2006) Diabetes , vol.55 , pp. 2132-2139
    • Wysocki, J.1    Ye, M.2    Soler, M.J.3
  • 16
    • 33750722109 scopus 로고    scopus 로고
    • Glomerular localization and expression of Angiotensin-converting enzyme 2 and Angiotensin-converting enzyme: implications for albuminuria in diabetes
    • PID: 17021266, COI: 1:CAS:528:DC%2BD28Xht1yjtbrP
    • Ye M, Wysocki J, William J, et al.: Glomerular localization and expression of Angiotensin-converting enzyme 2 and Angiotensin-converting enzyme: implications for albuminuria in diabetes. J Am Soc Nephrol 2006, 17:3067–3075.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 3067-3075
    • Ye, M.1    Wysocki, J.2    William, J.3
  • 17
    • 9644258509 scopus 로고    scopus 로고
    • Upregulation of angiotensin-converting enzyme 2 by all-trans retinoic acid in spontaneously hypertensive rats
    • PID: 15477383, COI: 1:CAS:528:DC%2BD2cXpvVGmu78%3D
    • Zhong JC, Huang DY, Yang YM, et al.: Upregulation of angiotensin-converting enzyme 2 by all-trans retinoic acid in spontaneously hypertensive rats. Hypertension 2004, 44:907–912.
    • (2004) Hypertension , vol.44 , pp. 907-912
    • Zhong, J.C.1    Huang, D.Y.2    Yang, Y.M.3
  • 18
    • 40849120442 scopus 로고    scopus 로고
    • Glomerular renin angiotensin system in streptozotocin diabetic and Zucker diabetic fatty rats
    • PID: 18355768, COI: 1:CAS:528:DC%2BD1cXjs1Sqt7g%3D
    • Leehey DJ, Singh AK, Bast JP, et al.: Glomerular renin angiotensin system in streptozotocin diabetic and Zucker diabetic fatty rats. Transl Res 2008, 151:208–216.
    • (2008) Transl Res , vol.151 , pp. 208-216
    • Leehey, D.J.1    Singh, A.K.2    Bast, J.P.3
  • 19
    • 2342472108 scopus 로고    scopus 로고
    • Increased ACE 2 and decreased ACE protein in renal tubules from diabetic mice: a renoprotective combination?
    • PID: 15078862, COI: 1:CAS:528:DC%2BD2cXjt1Gmt7s%3D
    • Ye M, Wysocki J, Naaz P, et al.: Increased ACE 2 and decreased ACE protein in renal tubules from diabetic mice: a renoprotective combination? Hypertension 2004, 43:1120–1125.
    • (2004) Hypertension , vol.43 , pp. 1120-1125
    • Ye, M.1    Wysocki, J.2    Naaz, P.3
  • 20
    • 39149145508 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2: possible role in hypertension and kidney disease
    • PID: 18367030, COI: 1:CAS:528:DC%2BD1cXivFGrsLg%3D
    • Wysocki J, Gonzalez-Pacheco FR, Batlle D: Angiotensin-converting enzyme 2: possible role in hypertension and kidney disease. Curr Hypertens Rep 2008, 10:70–77.
    • (2008) Curr Hypertens Rep , vol.10 , pp. 70-77
    • Wysocki, J.1    Gonzalez-Pacheco, F.R.2    Batlle, D.3
  • 21
    • 34548295365 scopus 로고    scopus 로고
    • Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury
    • PID: 17600118, COI: 1:CAS:528:DC%2BD2sXpsFaitbY%3D
    • Wong DW, Oudit GY, Reich H, et al.: Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury. Am J Pathol 2007, 171:438–451.
    • (2007) Am J Pathol , vol.171 , pp. 438-451
    • Wong, D.W.1    Oudit, G.Y.2    Reich, H.3
  • 22
    • 0141997294 scopus 로고    scopus 로고
    • Enhanced renal immunocytochemical expression of ANG-(1–7) and ACE2 during pregnancy
    • PID: 12874086, COI: 1:CAS:528:DC%2BD3sXosF2rt7Y%3D
    • Brosnihan KB, Neves LA, Joyner J, et al.: Enhanced renal immunocytochemical expression of ANG-(1–7) and ACE2 during pregnancy. Hypertension 2003, 42:749–753.
    • (2003) Hypertension , vol.42 , pp. 749-753
    • Brosnihan, K.B.1    Neves, L.A.2    Joyner, J.3
  • 23
    • 33748708412 scopus 로고    scopus 로고
    • Interferon-gamma and interleukin-4 downregulate expression of the SARS coronavirus receptor ACE2 in Vero E6 cells
    • PID: 16860835, COI: 1:CAS:528:DC%2BD28XpvV2lsr0%3D
    • de Lang A, Osterhaus AD, Haagmans BL: Interferon-gamma and interleukin-4 downregulate expression of the SARS coronavirus receptor ACE2 in Vero E6 cells. Virology 2006, 353:474–481.
    • (2006) Virology , vol.353 , pp. 474-481
    • de Lang, A.1    Osterhaus, A.D.2    Haagmans, B.L.3
  • 24
    • 27644585370 scopus 로고    scopus 로고
    • Mineralocorticoid receptor blocker increases angiotensin-converting enzyme 2 activity in congestive heart failure patients
    • PID: 16179584, COI: 1:CAS:528:DC%2BD2MXhtFCitr%2FN
    • Keidar S, Gamliel-Lazarovich A, Kaplan M, et al.: Mineralocorticoid receptor blocker increases angiotensin-converting enzyme 2 activity in congestive heart failure patients. Circ Res 2005, 97:946–953.
    • (2005) Circ Res , vol.97 , pp. 946-953
    • Keidar, S.1    Gamliel-Lazarovich, A.2    Kaplan, M.3
  • 25
    • 33644861536 scopus 로고    scopus 로고
    • Distinct roles for ANG II and ANG-(1–7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes
    • PID: 16176966, COI: 1:CAS:528:DC%2BD28XhsFKhsr8%3D
    • Gallagher PE, Chappell MC, Ferrario CM, Tallant EA: Distinct roles for ANG II and ANG-(1–7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes. Am J Physiol Cell Physiol 2006, 290:C420–C426.
    • (2006) Am J Physiol Cell Physiol , vol.290 , pp. C420-C426
    • Gallagher, P.E.1    Chappell, M.C.2    Ferrario, C.M.3    Tallant, E.A.4
  • 26
    • 43449084360 scopus 로고    scopus 로고
    • Angiotensin II up-regulates angiotensin I-converting enzyme (ACE), but down-regulates ACE2 via the AT1-ERK/p38 MAP kinase pathway
    • PID: 18403595, COI: 1:CAS:528:DC%2BD1cXmtFOntLw%3D
    • Koka V, Huang XR, Chung AC, et al.: Angiotensin II up-regulates angiotensin I-converting enzyme (ACE), but down-regulates ACE2 via the AT1-ERK/p38 MAP kinase pathway. Am J Pathol 2008, 172:1174–1183.
    • (2008) Am J Pathol , vol.172 , pp. 1174-1183
    • Koka, V.1    Huang, X.R.2    Chung, A.C.3
  • 27
    • 42649129357 scopus 로고    scopus 로고
    • Co-localization of angiotensin-converting enzyme 2-, octomer-4-and CD34-positive cells in rabbit atherosclerotic plaques
    • PID: 18192339
    • Zulli A, Rai S, Buxton BF, et al.: Co-localization of angiotensin-converting enzyme 2-, octomer-4-and CD34-positive cells in rabbit atherosclerotic plaques. Exp Physiol 2008, 93:564–569.
    • (2008) Exp Physiol , vol.93 , pp. 564-569
    • Zulli, A.1    Rai, S.2    Buxton, B.F.3
  • 28
    • 42649144447 scopus 로고    scopus 로고
    • Role of angiotensin-converting enzyme 2 and angiotensin(1–7) in 17beta-oestradiol regulation of renal pathology in renal wrap hypertension
    • PID: 18296494, COI: 1:CAS:528:DC%2BD1cXnvFChtbs%3D
    • Ji H, Menini S, Zheng W, et al.: Role of angiotensin-converting enzyme 2 and angiotensin(1–7) in 17beta-oestradiol regulation of renal pathology in renal wrap hypertension. Exp Physiol 2008, 93:648–657.
    • (2008) Exp Physiol , vol.93 , pp. 648-657
    • Ji, H.1    Menini, S.2    Zheng, W.3
  • 29
    • 34548051791 scopus 로고    scopus 로고
    • Activated protein C ameliorates LPS-induced acute kidney injury and downregulates renal INOS and angiotensin 2
    • PID: 17409278, COI: 1:CAS:528:DC%2BD2sXovVygtLw%3D
    • Gupta A, Rhodes GJ, Berg DT, et al.: Activated protein C ameliorates LPS-induced acute kidney injury and downregulates renal INOS and angiotensin 2. Am J Physiol Renal Physiol 2007, 293:F245–F254.
    • (2007) Am J Physiol Renal Physiol , vol.293 , pp. F245-F254
    • Gupta, A.1    Rhodes, G.J.2    Berg, D.T.3
  • 30
    • 85082389872 scopus 로고    scopus 로고
    • ACE2 is preferentially localized in the tunica media layer in renal vasculature and its expression increases after administration of a type 1 receptor antagonist [abstract]
    • COI: 1:CAS:528:DC%2BD28XnsF2itL0%3D
    • Soler MJ, Wysocki J, William J, et al.: ACE2 is preferentially localized in the tunica media layer in renal vasculature and its expression increases after administration of a type 1 receptor antagonist [abstract]. Hypertension 2006, 48:E25–E103 LB 12.
    • (2006) Hypertension , vol.48 , pp. E25-E103
    • Soler, M.J.1    Wysocki, J.2    William, J.3
  • 31
    • 33750589885 scopus 로고    scopus 로고
    • Enalapril attenuates downregulation of angiotensin-converting enzyme 2 in the late phase of ventricular dysfunction in myocardial infarcted rat
    • PID: 16908757, COI: 1:CAS:528:DC%2BD28XpsFOrsr4%3D
    • Ocaranza MP, Godoy I, Jalil JE, et al.: Enalapril attenuates downregulation of angiotensin-converting enzyme 2 in the late phase of ventricular dysfunction in myocardial infarcted rat. Hypertension 2006, 48:572–578.
    • (2006) Hypertension , vol.48 , pp. 572-578
    • Ocaranza, M.P.1    Godoy, I.2    Jalil, J.E.3
  • 32
    • 23944472129 scopus 로고    scopus 로고
    • Angiotensin II AT1 receptors regulate ACE2 and angiotensin-(1–7) expression in the aorta of spontaneously hypertensive rats
    • PID: 15833808, COI: 1:CAS:528:DC%2BD2MXhtVWktr7I
    • Igase M, Strawn WB, Gallagher PE, et al.: Angiotensin II AT1 receptors regulate ACE2 and angiotensin-(1–7) expression in the aorta of spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol 2005, 289:H1013–H1019.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289 , pp. H1013-H1019
    • Igase, M.1    Strawn, W.B.2    Gallagher, P.E.3
  • 33
    • 30944453306 scopus 로고    scopus 로고
    • Effects of renin-angiotensin system blockade on renal angiotensin-(1–7) forming enzymes and receptors
    • PID: 16221218, COI: 1:CAS:528:DC%2BD2MXht1SgtbbE
    • Ferrario CM, Jessup J, Gallagher PE, et al.: Effects of renin-angiotensin system blockade on renal angiotensin-(1–7) forming enzymes and receptors. Kidney Int 2005, 68:2189–2196.
    • (2005) Kidney Int , vol.68 , pp. 2189-2196
    • Ferrario, C.M.1    Jessup, J.2    Gallagher, P.E.3
  • 34
    • 34548822986 scopus 로고    scopus 로고
    • Effects of aldosterone and angiotensin II receptor blockade on cardiac angiotensinogen and angiotensin-converting enzyme 2 expression in Dahl salt-sensitive hypertensive rats
    • PID: 17903697, COI: 1:CAS:528:DC%2BD2sXhtFSnt7%2FN
    • Takeda Y, Zhu A, Yoneda T, et al.: Effects of aldosterone and angiotensin II receptor blockade on cardiac angiotensinogen and angiotensin-converting enzyme 2 expression in Dahl salt-sensitive hypertensive rats. Am J Hypertens 2007, 20:1119–1124.
    • (2007) Am J Hypertens , vol.20 , pp. 1119-1124
    • Takeda, Y.1    Zhu, A.2    Yoneda, T.3
  • 35
    • 33751188726 scopus 로고    scopus 로고
    • Effect of angiotensin II blockade on a new congenic model of hypertension derived from transgenic Ren-2 rats
    • PID: 16766648, COI: 1:CAS:528:DC%2BD28Xht1GnsLbN
    • Jessup JA, Gallagher PE, Averill DB, et al.: Effect of angiotensin II blockade on a new congenic model of hypertension derived from transgenic Ren-2 rats. Am J Physiol Heart Circ Physiol 2006, 291:H2166–H2172.
    • (2006) Am J Physiol Heart Circ Physiol , vol.291 , pp. H2166-H2172
    • Jessup, J.A.1    Gallagher, P.E.2    Averill, D.B.3
  • 36
    • 33846043074 scopus 로고    scopus 로고
    • Olmesartan is an angiotensin II receptor blocker with an inhibitory effect on angiotensin-converting enzyme
    • PID: 17345786, COI: 1:CAS:528:DC%2BD2sXhsFantL0%3D
    • Agata J, Ura N, Yoshida H, et al.: Olmesartan is an angiotensin II receptor blocker with an inhibitory effect on angiotensin-converting enzyme. Hypertens Res 2006, 29:865–874.
    • (2006) Hypertens Res , vol.29 , pp. 865-874
    • Agata, J.1    Ura, N.2    Yoshida, H.3
  • 37
    • 33845372803 scopus 로고    scopus 로고
    • Oxidative stress and glomerular filtration barrier injury: role of the renin-angiotensin system in the Ren2 transgenic rat
    • PID: 16788142, COI: 1:CAS:528:DC%2BD2sXktV2n
    • Whaley-Connell AT, Chowdhury NA, Hayden MR, et al.: Oxidative stress and glomerular filtration barrier injury: role of the renin-angiotensin system in the Ren2 transgenic rat. Am J Physiol Renal Physiol 2006, 291:F1308–F1314.
    • (2006) Am J Physiol Renal Physiol , vol.291 , pp. F1308-F1314
    • Whaley-Connell, A.T.1    Chowdhury, N.A.2    Hayden, M.R.3
  • 38
    • 33645834948 scopus 로고    scopus 로고
    • Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II
    • PID: 16505206, COI: 1:CAS:528:DC%2BD28XitlSgtLc%3D
    • Yamamoto K, Ohishi M, Katsuya T, et al.: Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II. Hypertension 2006, 47:718–726.
    • (2006) Hypertension , vol.47 , pp. 718-726
    • Yamamoto, K.1    Ohishi, M.2    Katsuya, T.3
  • 39
    • 34249900226 scopus 로고    scopus 로고
    • Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice
    • PID: 17499227, COI: 1:CAS:528:DC%2BD2sXmt1yntLc%3D
    • Oudit GY, Kassiri Z, Patel MP, et al.: Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice. Cardiovasc Res 2007, 75:29–39.
    • (2007) Cardiovasc Res , vol.75 , pp. 29-39
    • Oudit, G.Y.1    Kassiri, Z.2    Patel, M.P.3
  • 40
    • 1542547460 scopus 로고    scopus 로고
    • Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity
    • PID: 15007034, COI: 1:CAS:528:DC%2BD2cXjt1GmtrY%3D
    • Benson SC, Pershadsingh HA, Ho CI, et al.: Identification of telmisartan as a unique angiotensin II receptor antagonist with selective PPARgamma-modulating activity. Hypertension 2004, 43:993–1002.
    • (2004) Hypertension , vol.43 , pp. 993-1002
    • Benson, S.C.1    Pershadsingh, H.A.2    Ho, C.I.3
  • 41
    • 11144313062 scopus 로고    scopus 로고
    • Telmisartan is a promising cardiometabolic sartan due to its unique PPAR-gamma-inducing property
    • PID: 15617852, COI: 1:CAS:528:DC%2BD2cXhtFGhsrjJ
    • Yamagishi S, Takeuchi M: Telmisartan is a promising cardiometabolic sartan due to its unique PPAR-gamma-inducing property. Med Hypotheses 2005, 64:476–478.
    • (2005) Med Hypotheses , vol.64 , pp. 476-478
    • Yamagishi, S.1    Takeuchi, M.2
  • 42
    • 42549153011 scopus 로고    scopus 로고
    • Cardioprotective mechanism of telmisartan via PPAR-gamma-eNOS pathway in dahl salt-sensitive hypertensive rats
    • PID: 18437150, COI: 1:CAS:528:DC%2BD1cXltFeisrw%3D
    • Kobayashi N, Ohno T, Yoshida K, et al.: Cardioprotective mechanism of telmisartan via PPAR-gamma-eNOS pathway in dahl salt-sensitive hypertensive rats. Am J Hypertens 2008, 21:576–581.
    • (2008) Am J Hypertens , vol.21 , pp. 576-581
    • Kobayashi, N.1    Ohno, T.2    Yoshida, K.3
  • 43
    • 42449140640 scopus 로고    scopus 로고
    • ACE2 deficiency modifies renoprotection afforded by ACE inhibition in experimental diabetes
    • PID: 18235039, COI: 1:CAS:528:DC%2BD1cXksVGku78%3D
    • Tikellis C, Bialkowski K, Pete J, et al.: ACE2 deficiency modifies renoprotection afforded by ACE inhibition in experimental diabetes. Diabetes 2008, 57:1018–1025.
    • (2008) Diabetes , vol.57 , pp. 1018-1025
    • Tikellis, C.1    Bialkowski, K.2    Pete, J.3
  • 44
    • 42349105833 scopus 로고    scopus 로고
    • Structure-based identification of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents
    • PID: 18391097, COI: 1:CAS:528:DC%2BD1cXktlylsbY%3D
    • Hernandez Prada JA, Ferreira AJ, Katovich MJ, et al.: Structure-based identification of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents. Hypertension 2008, 51:1312–1317.
    • (2008) Hypertension , vol.51 , pp. 1312-1317
    • Hernandez Prada, J.A.1    Ferreira, A.J.2    Katovich, M.J.3
  • 45
    • 85082402485 scopus 로고    scopus 로고
    • Recombinant ACE2 attenuates angiotensin II induced hypertension [abstract]
    • COI: 1:CAS:528:DC%2BD2sXhtVCrtL3L
    • Ye M, Wysocki J, Rodriguez E, et al.: Recombinant ACE2 attenuates angiotensin II induced hypertension [abstract]. Hypertension 2007, 50:e75–e155.
    • (2007) Hypertension , vol.50 , pp. e75-e155
    • Ye, M.1    Wysocki, J.2    Rodriguez, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.