Aqueous extract of date fruit protects CA1 neurons against oxidative injury: An ultrastructural study

Current Topics in Nutraceutical Research

Volumn 6, Issue 3, 2008, Pages 125-130

  Marzieh, Panahi ^a   Majid, Asadi Shekaari ^b   Pari, Kalantari Pour Taj ^c   Ali, Safavi ^d  

^a AHVAZ JUNDISHAPUR UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b KERMAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c ISLAMIC AZAD UNIVERSITY   (Iran)

^d SHIRAZ UNIVERSITY   (Iran)

Author keywords

Antioxidant; CA1; Dates; Electron microscopy; Ischemia; Phoenix dactylifera

Indexed keywords

DATE EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; DATE (FRUIT); HIPPOCAMPUS; MALE; NERVE CELL; NEUROPROTECTION; NONHUMAN; RAT; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

ANIMALIA; PHOENIX DACTYLIFERA; RATTUS;

EID: 58149391322     PISSN: 15407535     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Al-Qarawi, A. A., Abdel-Rahman, H., Ali, B. H., Mousa, H. M. and El-Mougy. (2005) The ameliorative effect of dates (Phoenix dactylifera L.) On ethanol-induced gastric ulcer in rats. Journal of Ethnopharmacology 98: 313-317.
2. Al-Shahib, W. and Marshall, R. (2003) The fruit of the date palm: its possible use as the best food for the future? International Journal of food sciences and nutrition 54: 247-259.
3. Asadi-Shekaari, M. and Rajabalin, S. (2004) Antioxidative effect of aqueous date fruit extract in PC12 cell line. Iranian journal of pharmaceutical Research, 82, supplement 1: p72 abstracts of posters/Medicinal plants and the nervous system.
4. Biglari, F., Alkarkhi, F. M. and Mat Easa, A. (2008) Antioxidant activity and phenolic content of various date palm (Phoenix dactylifera) fruits from Iran. Food Chemistry 107: 1636-1641.
5. Chen, J., Nagayama, T., Jin, K., Stelter, R. A., Zhu, R. L., Grahm, S. H. and Simon, R. P. (1998) Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia. Journal Neuroscience 18: 4914-4928.
6. Choi, D. W. (1996) Ischemia-induced neuronal apoptosis. Current Opinions in Neurobiology 6:667-672.
7. Clark, W. M., Rinker, L. G., Lessov, N. S., Lowery, S. L. and Cipolla M.J. (2001) Efficacy of antioxidant therapies in transient focal ischemia in mice. Stroke 32:1000-1004.
8. Cui, K., Luo, X., Xu, K. and Ven Murthy, M.R. (2004) Role of oxidative stress in neurodegeneration: recent developments in assay methods for oxidative stress and nurraceutical antioxidants. Progress in Neuro-Pschychopharmacology & Biological Psychiatry 28:771-99.
9. Fukuda, T., Wang, H., Nakanishi, H., Yamamoto, K. and Kosaka, T (1999) Novel non-apoptotic morphological changes in neurons of the mouse hippocampus following transient hypoxic-ischemia. Neuroscience Research 33:49-55.
10. Garcia, J.H., Wagner, S., Liu, K.F. and Hu X.J. (1995) Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Stroke 26:627-635.
11. Ikeda, K., Negishi, H. and Yamori, Y. (2003) Antioxidant nutrients and hypoxia/ischemia brain injury in rodents. Toxicology 189:55-61.
12. Ishurd, O. and Kennedy J. F. (2005) The anti-cancer activity of polysaccharide prepared from Libyan dates (Phoenix dactylifera L.). Carbohydrate Polymers 59:531-535.
13. Leionen, J.S., Ahonen, J. P., Lonnort, K., Johkonen, M., Dastidar, P., Molinar, G. and Alho, H. (2000) Low plasma antioxidant activity is associated with high lesion volume and neurological impairment in stroke. Stroke 31:33-39.
14. Lukic-Panin, V., Kamiya, T., Zhang, H., Hayashi, T., Tsuchiya, A., Sehara, Y., Deguchi, K., Yamashita, T. and Abe K. (2007) Prevention of neuronal damage by calcium channel blockers with antioxidative effects after transient focal ischemia in rats. Brain research 1176:143-150.
15. Longa, E. Z., Weinstein, P.R., Carlson, S. and Cummins R. (1989) Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20:84-91.
16. Lyden, P. and Wahlgren, N. G. (2000) Mechanisms of action of neuroprotectant in stroke. Journal of stroke and Cerebrovascular diseases 9:9-14.
17. MacManus, J. P and Linnik, M. D. (1997) Gene expression induced by cerebral ischemia: an apoptotic perspective. Journal of cerebral Blood Flow & Metabolism 17:825-832.
18. Mansuri, A., Embarek, G., Kokkalon, E. and Kefalas, P. (2005) Phenolic profile and antioxidant activity of the Algerian ripe date palm fruit (Phoenix dactylifera). Food chemistry 89:411-420.
19. Maynard, K. I., Ayoub, I. A. and Shen, C. C. (2001) Delayed treatment with nicotinamide extends the degree and duration of neuroprotection by reducing infarction and improving behavior scores up to two weeks following transient focal cerebral ischemia in Wistar rats. Annals of NY Academy of Sciences 939: 416-424.
20. Miller NJ, Rice-Evans C, Davis MJ, Gopinthan V, Milner A. (1993) A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates. Clinical Science (Lond) 84: 407-412.
21. Puri, A., Sahai, R., Singh, K. L., Saxena, R, P., Tandon, J. S. and Saxena K. C. (2000). "Immunostimulant activity of dry fruits and plant materials used in Indian traditional medical system for mothers after child birth and invalids", Journal of Ethnopharmacology 71: 89-92.
22. Saleem, S. A., Baloch, A. K., Baloch, M. K., Baloch, W. A. and Ghaffoor A. (2005) Accelerated ripening of Dhakki dates by artificial means: ripening by acetic acid and sodium chloride. Journal of Food Engineering 70: 61-66.
23. Sallal, A.K. and Ashkenani, A. (1989) Effect of date extract on growth and spore germination of Bacillus subtilis. Microbios 59: 203-210.
24. Sallal, A.K., El-Teen, K.H. and Abderahman, S. (1996) Effect of date extract on growth and morphology of Candida albicans. Biomed Letters 53: 119-123.
25. Schwartz-Bloom, R. D., Miller, A. D., Evenson, D. A., Grain, B. J. and Nadler, J. V. (2000) Benzodiazepines protect hippocampal neurons from degeneration after transient cerebral ischemia: an ultrastructural study. Neuroscience 98: 471-484.
26. Spielmeyer, W. (1925) Zür pathogenese orlich elektiven gehirnveranderungen. Z Ges Neurol Psychiatry 99: 756-776,
27. quoted by Lipton, P. (1999). "Ischemic cell death in brain neurons", Physiological Review 79: 1431-1568.
28. Sugawara, T., Fujimura, M., Morita-Fujimura, Y., Kawase, M. and Chan, P. H. (1999) Mitochondrial release of Cytochrome c corresponds to the selective vulnerability of hippocampal CA1 neurons in rats after transient global cerebral ischemia. Journal of Neuroscience 19: 1-6.
29. Tan, D. X., Chen, L. D., Poeggeler, B., Manchester, L. C. and Reiter, L. G. (1993) Melatonin: a potent endogenous hydroxyl radical scavenger. Endocrine Journal 1: 57-60.
30. Vajragupta O, Boonchoong P, Sumanot Y, Watanabe H, Wongkrajang Y, Kammasud N. (2003) Manganese-based complexes of radical scavengers as neuroprotective agents. Bioorganic Med Chemistry 15: 2329-2337.
31. Vayalil PK. (2002) Antioxidant and antimutagenic properties of aqueous extract of date fruit (Phoenix dactylifera L. Arecaceae). Journal of Agriculture and Food Chemistry 50:610-617.
32. Winkelmann, E. R., Charcansky, A., Faccioni-Heuser, M. C., Netto, C. A. and Achaval, M. (2006) An ultrastructural analysis of cellular death in the CA1 field in the rat hippocampus after transient forebrain ischemia followed by 2, 4 and 10 days of reperfusion. Anat Embryol (Berl) 211: 423-434.
33. Yousef S, Atif F, Ahmad M, Hoda MN, Khan MB, Ishrat T, Islam F. (2007) Selenium plays a modulatory role against cerebral ischemia-induced neuronal damage in rat hippocampus. Brain Research 25: 218-225.
34. Zeng, Y. S. and Xu, Z. C. (2000) Co-existence of necrosis and apoptosis in rat hippocampus following transient forebrain ischemia. Neuroscience Research 37: 113-125.