Farnesyltransferase inhibitors-induced autophagy: Alternative mechanisms?

Autophagy

Volumn 5, Issue 1, 2009, Pages 129-131

  Pan, Jingxuan ^a   Song, Enlin ^a   Cheng, Chao ^a   Lee, Mong Hong ^b   Yeung, Sai Ching Jim ^b  

^a SUN YAT SEN UNIVERSITY   (China)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Autophagy; DNA damage; Farnesyltransferase inhibitor; Ras; Reactive oxygen species; Rheb

Indexed keywords

3 METHYLADENINE; DNA; LONAFARNIB; MAMMALIAN TARGET OF RAPAMYCIN; N [[5 [(2 AMINO 3 MERCAPTOPROPYL)AMINO][1,1' BIPHENYL] 2 YL]CARBONYL]METHIONINE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN FARNESYLTRANSFERASE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; PROTEIN KINASE B; RAPAMYCIN; RAS PROTEIN; REACTIVE OXYGEN METABOLITE; RHEB PROTEIN; TEMOZOLOMIDE; TIOGUANINE;

ARTICLE; AUTOPHAGY; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; DRUG EFFECT; DRUG MECHANISM; DRUG TARGETING; ENZYME INHIBITION; HUMAN; INHIBITION KINETICS; NONHUMAN; PROTEIN TARGETING; RECEPTOR BINDING; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

EID: 58149384078     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.5.1.7329     Document Type: Article

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