Inhibition of gap junctional intercellular communication by the green tea polyphenol (-)-Epigallocatechin gallate in normal rat liver epithelial cells

Journal of Agricultural and Food Chemistry

Volumn 56, Issue 21, 2008, Pages 10422-10427

  Kang, Nam Joo ^a,b   Lee, Kyung Mi ^a   Kim, Jong Hun ^b   Lee, Bo Kyung ^b   Kwon, Jung Yeon ^b   Lee, Ki Won ^b   Lee, Hyong Joo ^a  

^a Seoul National University   (South Korea)

^b Konkuk University   (South Korea)

Author keywords

( ) Epigallocatechin gallate; Connexin 43; Extracellular signal regulated protein kinase; Gap junctional intercellular communication

Indexed keywords

RATTUS;

CATECHIN; CONNEXIN 43; DRUG DERIVATIVE; EPIGALLOCATECHIN GALLATE; FLAVONOID; MITOGEN ACTIVATED PROTEIN KINASE 3; PHENOL DERIVATIVE; POLYPHENOLS; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; CELL COMMUNICATION; CELL CULTURE; CELL JUNCTION; CHEMISTRY; DRUG EFFECT; EPITHELIUM CELL; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; RAT; TEA;

ANIMALS; CATECHIN; CELL COMMUNICATION; CELLS, CULTURED; CONNEXIN 43; EPITHELIAL CELLS; FLAVONOIDS; GAP JUNCTIONS; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHENOLS; PHOSPHORYLATION; RATS; TEA;

EID: 58149350133     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf801981w     Document Type: Article

References (38)

1. Park, O. J.; Surh, Y.-J. Chemopreventive potential of epigallo-catechin gallate and genistein: evidence from epidemiological and laboratory studies. Toxicol. Lett. 2004, 150 (1). 43-56.
2. Surh, Y.-J. Cancer chemoprevention with dietary phytochemicals. Nature Rev. Cancer 2003. 3 (10), 768-780.
3. Michels, K. B.; Willett, W. C.; Fuchs, C. S.; Giovannucci, E. Coffee, tea, and caffeine consumption and incidence of colon and rectal cancer. J. Natl. Cancer Inst. 2005, 97 (4), 282-292.
4. Tavani, A.; Vecchia, C. Coffee, decaffeinated coffee, tea and cancer of the colon and rectum: a review of epidemiological studies. 1990-2003. Cancer Causes Control. 2004, 15 (8), 743-757.
5. Hoshiyama, Y.; Kawaguchi, T.; Miura, Y.; Mizoue, T.; Tokui, N.; Yatsuya, H.; Sakata, K.; Kondo, T.; Kikuchi, S.; Toyoshima, H.; Hayakawa, N.: Tamakoshi, A.; Yoshimura, T. Green tea and stomach cancer-a short review of prospective studies. J. Epidemiol. 2005. 2, 109112).
6. Higdon, J. V.; Frei, B. Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions. Crit. Rev. Food Sci. Nutr. 2003. 43 (1), 89-143.
7. Furukawa, A.; Oikawa, S.; Murata, M.; Hiraku, Y.; Kawanishi. S. (-) -Epigallocatechin gallate causes oxidative damage to isolated and cellular DNA. Biochem. Pharmacol. 2003, 66 (9), 1769-1778.
8. Hirose, M.; Hoshiya, T.; Mizoguchi, Y.; Nakamura, A.; Akagi, K.; Shirai, T. Green tea catechins enhance tumor development in the colon without effects in the lung or thyroid after pretreatment with 1, 2-Dimethylhydrazine or 2, 2′-dihydroxy-di-n-propylnitro-samine in male F344 rats. Cancer Lett. 2001, 168 (1), 23-29.
9. Schmidt, M.; Schmitz, H. J.: Baumgart, A.; Guedon, D.; Netsch, M. 1.; Kreuter, M. H.; Schmidlin, C. B.; Schrenk, D. Toxicity of green tea extracts and their constituents in rat hepatocytes in primary culture. Food Chem. Toxicol. 2005, 43 (2), 307-314.
10. Galati, G.; Lin, A.; Sultan, A. M.; O'Brien, P. J. Cellular and in vivo hepatotoxicity caused by green tea phenolic acids and catechins. Free Radical Biol. Med. 2006, 40 (4), 570-580.
11. Galati. G.; O'Brien. P. J. Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties. Free. Radical Biol. Med. 2004. 37 (3), 287-303.
12. Trosko. J. E.; Chang. C. C. Modulation of cell-cell communication in the cause and chemoprevention/chemotherapy of cancer. BioFactors 2000, 12, 259-263.
13. Kumar, M. N.; Gilula, N. B. The gap junction communication channel. Cell 1996, 84, 381-388.
14. Trosko, J. E.; Chang, C. C.; Madhukar, B. V. The role of modulated gap junctional intercellular communication in epige-netic toxicology. Risk Anal. 1994, 14 (3), 303-12.
15. Sai, K.; Upham, B. L.; Kang, K. S.; Hasegawa, R.; Inoue, T.; Trosko. J. E. Inhibitory effect of pentachlorophenol on gap junctional intercellular communication in rat liver epithelial cells in vitro. Cancer Lett. 1998, 130 (1-2), 9-17.
16. Huang, R. P.; Peng, A.; Hossain, M. Z.; Fan, Y.; Jagdale, A.; Boynton. A. L. Tumor promotion by hydrogen peroxide in rat liver epithelial cells. Carcinogenesis 1999, 20 (3). 485-492.
17. Rivedal, E.; Opsahl, H. Role of PKC and MAP kinase in EGF-and TPA-induced connexin43 phosphorylation and inhibition of gap junction intercellular communication in rat liver epithelial cells. Carcinogenesis 2001, 22, 1543-1550.
18. Na, H. K.; Wilson, M. R.; Kang, K. S.: Chang, C. C: Grunberger, D.: Trosko, J. E. Restoration of gap junctional intercellular communication by caffeic acid phenethyl ester (CAPE) in a ras-transformed rat liver epithelial cell line. Cancer Lett. 2000. 157. 31-38.
19. Sai, K.; Kanno, J.; Hasegawa, R.; Trosko, J. E.; Inoue. T. Prevention of the down-regulation of gap junctional intercellular communication by green tea in the liver of mice fed pentachlorophenol. Carcinogenesis 2000, 21, 1671-1676.
20. Huang. R. P.; Peng, A.: Golard, A.; Hossain, M. Z.: Huang, R.: Liu, Y. G.; Boynton, A. L. Hydrogen peroxide promotes transformation of rat liver non-neoplastic epithelial cells through activation of epidermal growth factor receptor. Mol. Carcinog. 2001, 30 (4), 209-217.
21. Cho, J. H.; Cho, S. D.; Hu, H.; Kim, S. H.; Lee, S. K.; Lee, Y. S.: Kang, K. S. The roles of ERK1/2 and p38 MAP kinases in the preventive mechanisms of mushroom Phellinus linteus against the inhibition of gap junctional intercellular communication by hydrogen peroxide. Carcinogenesis 2002, 23 (7). 1163-1169.
22. 2. Cancer Lett. 2000, 152 (1), 97-106.
23. Chun, K.-S.; Keum, Y. S.; Han, S. S.; Song, Y. S.; Kim, S. H.; Surh, Y.-J. Curcumin inhibits phorbol ester-induced expression of cyclooxygenase-2 in mouse skin through suppression of extracellular signal-regulated kinase activity and NF-kappaB activation. Carcinogenesis 2003, 24 (9), 1515-1524.
24. Nourooz-Zadeh. J. Ferrous ion oxidation in presence of xylenol orange for detection of lipid hydroperoxides in plasma. Methods Enzymol. 1999, 300, 58-62.
25. Trosko, J. E. Gap junctional intercellular communication as a biological "Rosetta stone" in understanding, in a systems biological manner, stem cell behavior, mechanisms of epigenetic toxicology, chemoprevention and chemotherapy. J. Membr. Biol. 2007, 218, 93-100.
26. Ale-Agha, N.; Stahl, W.; Sies, H. (-) -Epicatechin effects in rat liver epithelial cells: stimulation of gap junctional communication and counteraction of its loss due to the tumor promoter 12-0-tetradecanoylphorbol-13-acetate. Biochem. Pharmacol. 2002. 63 (12), 2145-2149.
27. Takahashi, H.; Nomata, K.; Mori, K; Matsuo, M.; Miyaguchi. T.; Noguchi, M.: Kanetake, H. The preventive effect of green tea on the gap junction intercellular communication in renal epithelial cells treated with a renal carcinogen. Anticancer Res. 2004, 24 (6), 3757-62.
28. Sigler, K.; Ruch, R. J. Enhancement of gap junctional intercellular communication in tumor promoter-treated cells by components of green tea. Cancer Lett 1993, 69 (1). 15-9.
29. Lee, S. J.; Lee, K. W.; Lee, H. J. Abies nephrolepis leaf phenolics prevent the inhibition of gap junction intercellular communication by hydrogen peroxide in rat liver epithelial cells. BioFactors 2004, 21 (1-4), 357-360.
30. Na, H. K.; Kim, E. H.; Jung, J. H.; Lee, H. H.; Hyun, J. W.; Surh, Y. J. (-) -Epigallocatechin gallate induces Nrf2-mediated antioxidant enzyme expression via activation of PDK and ERK in human mammary epithelial cells. Arch. Biochem. Biophys. 2008
31. Klotz, L. O.; Patak, P.; Ale-Agha, N.; Buchczyk, D. P.; Abdel-mohsen, K.; Gerber, P. A.; Montfort, C. v.; Sies, H. 2-Methyl-1, 4-naphthoquinone. vitamin K (3), decreases gap-junctional intercellular communication via activation of the epidermal growth factor receptor/extracellular signal-regulated kinase cascade. Cancer Res. 2002, 62 (17), 4922-4928.
32. Abdelmohsen, K.; Gerber, P. A.: Montfort, C. v. : Sies, H.; Klotz, L. O. Epidermal growth factor receptor is a common mediator of quinone-induced signaling leading to phosphorylation of connexin-43: role of glutathione and tyrosine phosphatases. J. Biol. Chem. 2003. 278 (40), 38360-38367.
33. Upham, B. L.; Kang, K. S.; Cho, H. Y.; Trosko, J. E. Hydrogen peroxide inhibits gap junctional intercellular communication in glutathione sufficient but not glutathione deficient cells. Carcinogenesis 1997, 18 (1). 37-42.
34. Sharov, V. S.; Briviba. K; Sies, H. Peroxynitrite diminishes gap junctional communication: protection by selenite supplementation. IUBMB Life 1999, 48, 379-384.
35. Huang, R. P.; Peng, A.; Hossain, M. Z.: Fan, Y.; Jagdale, A.; Boynton, A. L. Tumor promotion by hydrogen peroxide in rat liver epithelial cells. Carcinogenesis 1999, 20 (3). 485-92.
36. Huang. R. P.; Peng, A.: Golard, A.; Hossain, M. Z.: Huang, R.: Liu, Y. G.; Boynton, A. L. Hydrogen peroxide promotes transformation of rat liver non-neoplastic epithelial cells through activation of epidermal growth factor receptor. Mol Carcinog. 2001, 30 (4), 209-17.
37. Lee, K W.; Hur. H. J.; Lee. H. J.: Lee. C. Y. Antiproliferative effects of dietary phenolic substances and hydrogen peroxide. J. Agtic. Food Chem. 2005. 53 (6), 1990-1995.
38. Lambert, J. D.; Lee, M.-J.; Diamond, L.; Ju, J.; Hong, J.; Bose, M.; Newmark, H. L.; Yang, C. S. Dose-dependent levels of epigallocatechin-3-gallate in human colon cancer cells and mouse plasma and tissues. Drug Metab. Dispos. 2006, 34 (1), 8-11.