Dysregulation of neurosteroids in obsessive compulsive disorder

Journal of Psychiatric Research

Volumn 43, Issue 4, 2009, Pages 442-445

  Bigos, K L ^a   Folan, M M ^a   Jones, M R ^b   Haas, G L ^b,c   Kroboth, F J ^b   Kroboth, P D ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Cortisol; Dehydroepiandrosterone; DHEA; Hormones; Obsessive compulsive disorder; OCD

Indexed keywords

HYDROCORTISONE; NEUROSTEROID; PRASTERONE; PRASTERONE SULFATE;

ADULT; ANDROGEN BLOOD LEVEL; CASE REPORT; CIRCADIAN RHYTHM; CONTROLLED STUDY; DISEASE ASSOCIATION; HUMAN; HYDROCORTISONE BLOOD LEVEL; LETTER; MALE; OBSESSIVE COMPULSIVE DISORDER; PRIORITY JOURNAL;

ADULT; CIRCADIAN RHYTHM; DEHYDROEPIANDROSTERONE; DEHYDROEPIANDROSTERONE SULFATE; HUMANS; HYDROCORTISONE; MALE; OBSESSIVE-COMPULSIVE DISORDER; RADIOIMMUNOASSAY; TIME FACTORS; YOUNG ADULT;

EID: 58149340255     PISSN: 00223956     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2008.04.007     Document Type: Letter

References (25)

1. Altemus M., Pigott T., Kalogeras K.T., Demitrack M., Dubbert B., Murphy D.L., et al. Abnormalities in the regulation of vasopressin and corticotropin releasing factor secretion in obsessive-compulsive disorder. Archives of General Psychiatry 49 (1992) 9-20
2. Bailly D., Servant D., Dewailly D., Beuscart R., Racadot A., and Fossati P. Corticotropin releasing factor stimulation test in obsessive compulsive disorder. Biological Psychiatry 35 (1994) 143-146
3. Bernardi F., Casarosa E., Pluchino N., Palumbo M., Genazzani A.D., Luisi S., et al. Effect of dehydroepiandrosterone on central and peripheral levels of allopregnanolone and beta-endorphin. Fertility and Sterility 83 (2005) 1161-1168
4. Brambilla F., Mellado C., Alciati A., Pisu M.G., Purdy R.H., Zanone S., et al. Plasma concentrations of anxiolytic neuroactive steroids in men with panic disorder. Psychiatry Research 135 (2005) 185-190
5. Catapano F., Monteleone P., Fuschino A., Maj M., and Kemali D. Melatonin and cortisol secretion in patients with primary obsessive-compulsive disorder. Psychiatry Research 44 (1992) 217-225
6. Catapano F., Monteleone P., Maj M., and Kemali D. Dexamethasone suppression test in patients with primary obsessive-compulsive disorder and in healthy controls. Neuropsychobiology 23 (1990) 53-56
7. Compagnone N.A., and Mellon S.H. Neurosteroids: biosynthesis and function of these novel neuromodulators. Frontiers in Neuroendocrinology 21 (2000) 1-56
8. Cottraux J.A., Bouvard M., Claustrat B., and Juenet C. Abnormal dexamethasone suppression test in primary obsessive-compulsive patients: a confirmatory report. Psychiatry Research 13 (1984) 157-165
9. Eser D., Schüle C., Romeo E., Baghai T.C., di Michele F., Pasini A., et al. Neuropsychopharmacological properties of neuroactive steroids in depression and anxiety disorders. Psychopharmacology 186 (2006) 373-387
10. Fabian T.J., Dew M.A., Pollock B.G., Reynolds III C.F., Mulsant B.H., et al. Endogenous concentrations of DHEA and DHEA-S decrease with remission of depression in older adults. Biological Psychiatry 50 (2001) 767-774
11. First MB, Spitzer RL, Gibbon M, Williams JBW. Structured clinical interview for DSM-IV Axis I disorders - patient edition (SCID-I/P, Version 2.0). New York: Biometrics Research Department, 1995.
12. Guazzo E.P., Kirkpatrick P.J., Goodyer I.M., Shiers H.M., and Herbert J. Cortisol, dehydroepiandrosterone (DHEA), and DHEA sulfate in the cerebrospinal fluid of man: relation to blood levels and the effects of age. Journal of Clinical Endocrinology and Metabolism 81 (1996) 3951-3960
13. Heuser I., Deuschle M., Luppa P., Schweiger U., Standhardt H., and Weber B. Increased diurnal plasma concentrations of dehydroepiandrosterone in depressed patients. Journal of Clinical Endocrinology and Metabolism 83 (1998) 3130-3133
14. Hsiao C.-C. Positive correlation between anxiety severity and plasma levels of dehydroepiandrosterone sulfate in medication-free patients experiencing a major episode of depression. Psychiatry and Clinical Neurosciences 60 (2006) 746-750
15. Le Mellédo J.-M., and Baker G.B. Neuroactive steroids and anxiety disorders. Journal of Psychiatry Neuroscience 27 (2002) 161-165
16. Le Mellédo J.-M., and Baker G.B. Role of progesterone and other neuroactive steroids in anxiety disorders. Expert Review of Neurotherapeutics 4 (2004) 851-860
17. Leckman J.F., Goodman W.K., North W.G., Chappell P.B., Price L.H., Pauls D.L., et al. Elevated cerebrospinal fluid levels of oxytocin in obsessive-compulsive disorder. Comparison with Tourette's syndrome and healthy controls. Archives of General Psychiatry 51 (1994) 782-792
18. A receptor. Mechanism of action and physiological significance. Progress in Neurobiology 38 (1992) 379-395
19. A receptor. Brain Research 526 (1990) 143-146
20. 3H]norepianephrine release evoked by N-methyl-d-aspartate in the rat hippocampus. Proceedings of the National Academy of Sciences of the United States of America 92 (1995) 3774-3778
21. Monteleone P., Catapano F., Del Buono G., and Maj M. Circadian rhythms of melatonin, cortisol, and prolactin in patients with obsessive-compulsive disorder. Acta Psychiatrica Scandinavica 89 (1994) 411-415
22. Monteleone P., Luisi M., Colurgio B., Casarosa E., Ioime R., Genazzani A.R., et al. Plasma levels of neuroactive steroids are increased in untreated women with anorexia nervosa or bulimia nervosa. Psychosomatic Medicine 63 (2001) 62-68
23. Reddy D.S., and Kulkarni S.K. Differential anxiolytic effects of neurosteroids in the mirrored chamber behavior test in mice. Brain Research 752 (1997) 61-71
24. Rupprecht R. The neuropsychopharmacological potential of neuroactive steroids. Journal of Psychiatry Research 31 (1997) 297-314
25. Sullivan G.M., Coplan J.D., Kent J.M., and Gorman J.M. The noradrenergic system in pathological anxiety: a focus on panic with relevance to generalized anxiety and phobias. Biological Psychiatry 46 (1999) 1205-1218