The effect of vitamin C supplementation in healthy dogs on antioxidative capacity and immune parameters

Journal of Animal Physiology and Animal Nutrition

Volumn 93, Issue 1, 2009, Pages 26-34

  Hesta, M ^a   Ottermans, C ^a   Krammer Lukas, S ^b   Zentek, J ^c   Hellweg, P ^c   Buyse, J ^d   Janssens, G P J ^a  

^a GHENT UNIVERSITY   (Belgium)

^b DSM NUTRITIONAL PRODUCTS LTD   (Switzerland)

^c FREIE UNIVERSITÄT BERLIN   (Germany)

^d UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Antioxidants; Ascorbic acid; Dogs; Vitamin C

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; THIOBARBITURIC ACID REACTIVE SUBSTANCE; URIC ACID;

ANIMAL; ANIMAL FOOD; ANTIBODY PRODUCTION; ARTICLE; BIOSYNTHESIS; BLOOD; CELLULAR IMMUNITY; CROSSOVER PROCEDURE; DIET SUPPLEMENTATION; DOG; DOSE RESPONSE; DRUG EFFECT; FEMALE; IMMUNOLOGY; MALE; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY; RANDOMIZATION;

ANIMAL FEED; ANIMAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; ANIMALS; ANTIBODY FORMATION; ANTIOXIDANTS; ASCORBIC ACID; CROSS-OVER STUDIES; DIETARY SUPPLEMENTS; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; IMMUNITY, CELLULAR; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; MALE; OXIDATION-REDUCTION; RANDOM ALLOCATION; THIOBARBITURIC ACID REACTIVE SUBSTANCES; URIC ACID; VITAMIN E;

CANIS FAMILIARIS; PHYTOLACCACEAE;

EID: 58149327037     PISSN: 09312439     EISSN: 14390396     Source Type: Journal    
DOI: 10.1111/j.1439-0396.2007.00774.x     Document Type: Article

References (31)

1. Alessio, H. Goldfarb, A. Cutler, R., 1988 : MDA content increases in fast and slow twitch skeletal muscle with intensity of exercise in a rat. American Journal of Physiology - Cell Physiology 255, C874 C877.
2. Anderson, R. Smit, M. Joone, G. Van Staden, A., 1990 : Vitamin C and cellular immune functions. Protection against hypochlorous acid mediated inactivation of glyceraldehyde-3-phophate dehydrogenase and ATP generation in humane leucocytes as a possible mechanism of ascorbate-mediated immunostimulation. Annals of the New York Academy of Science 587, 34 48.
3. Baker, H. Schor, S. Murphy, B. Deangelis, B. Feingold, S. Frank, O., 1986 : Blood vitamin and choline concentration in healthy domestic cats, dogs and horses. American Journal of Veterinary Research 47, 1468 1471.
4. Bergmeyer, H., 1980 : IFCC methods for the measurement of catalytic concentrations of enzymes: Part 3. IFCC method for alanine aminotransferase (L-alanine: 2-oxoglutarate aminotransferase, EC 2.6.1.2). Clinica Chimica Acta 105, 147 154.
5. Burton, G. Wronska, U. Stone, L. Foster, D. Ingold, K., 1990 : Biokinetics of dietary RRR-alpha-tocopherol in the male guinea pig at 3 dietary levels of vitamin C and 2 levels of vitamin E evidence that vitamin C does not spare vitamin E in vivo. Lipids 25, 199 210.
6. Chatterjee, I. Majumder, A. Nandi, B. Subramanian, N., 1975 : Synthesis and some major functions of vitamin C in animals. Annals of the New York Academy of Science 258, 24 47.
7. Chen, L. Chang, H., 1978 : Effect of high dietary levels of vitamin C on tissue antioxidant status of guinea pigs. Federation Proceedings 37, 589 589.
8. Chen, L. Chang, H., 1979 : Effects of high level of vitamin C on tissue antioxidant status of guinea-pigs. International Journal for Vitamin and Nutrition Research 49, 87 91.
9. Donoghue, S. Kronfeld, D. Dunlap, H. Schryver, H., 1993 : Vitamin C supplementation of sled dogs affects responses to racing and stress. Recueil de Medecine Veterinaire 169, 773 777.
10. Eichenberger, B. Pfirter, H. Wenk, C. Gebert, S, 2004 : Influence of dietary vitamin E and C supplementation on vitamin E and C content and thiobarbituric acid reactive substances (TBARS) in different tissues of growing pigs. Archives of Animal Nutrition 58, 195 208.
11. Heaton, P. Reed, C. Mann, S. Ransley, R. Stevenson, J. Charlton, C. Smith, B. Harper, J. Rawlings, J., 2002 : Role of dietary antioxidants to protect against DNA damage in adult dogs. Journal of Nutrition 132, 1720S 1724S.
12. Jentzsch, A. Bachmann, H. Furst, P. Biesalski, H., 1996 : Improved analysis of malondialdehyde in human body fluids. Free Radical Biology and Medicine 20, 251 256.
13. Lapenna, D. Ciofani, G. Bruno, C. Pierdomenico, S. Cuccurollo, F., 2001 : Antioxidant activity of amiodarone on human lipoprotein oxidation. British Journal of Pharmacology 133, 739 745.
14. Leonhardt, M. Gebert, S. Wenk, C., 1996 : Stability of alpha-tocopherol, thiamin, riboflavine and retinol in pork muscle and liver during heating as affected by dietary supplementation. Journal of food Science 61, 1048.
15. Marshall, R. Scott, K. Hill, R. Lewis, D. Sundstrom, D. Jones, G. Harper, J., 2002 : Supplemental vitamin C appears to slow racing greyhounds. Journal of Nutrition 132, 1616S 1621S.
16. National Research Council of the National Acadamies, 2006a : Vitamins. Nutrient Requirements of Dogs and Cats, Animal Nutrition Series. National Academies Press, Washington, DC, pp. 234 235.
17. National Research Council of the National Acadamies, 2006b : Physical activity and environment. Nutrient Requirements of Dogs and Cats, Animal Nutrition Series. National Academies Press, Washington, DC, pp. 303.
18. National Research Council of the National Acadamies, 2006c : Nutrient requirements and dietary nutrient concentrations. Nutrient Requirements of Dogs and Cats, Animal Nutrition Series. National Academies Press, Washington, DC, pp. 360.
19. Packer, J. Slater, T. Willson, R., 1979 : Direct observation of a free radical interaction between vitamin E and vitamin C. Nature 278, 737 738.
20. Piercy, R. Hinchcliff, K. DiSilvestro, R. Reinhart, G. Baskin, C. Hayek, M. Burr, J. Swenson, R., 2000 : Effect of dietary supplements containing antioxidants on attenuation of muscle damage in exercising sled dogs. American Journal of Veterinary Research 61, 1438 1445.
21. Powers, S., 2004 : Dietary antioxidants and exercise. Journal of Sports Sciences 22, 81 94.
22. Scott, K. Hill, R. Lewis, D. Gronwall, R. Sundstorm, D. Jones, G. Harper, J., 2002 : Serum ascorbic acid concentrations in previously unsupplemented greyhounds after administration of a single dose of ascorbic acid intravenously or per os. Journal of Animal Physiology and Animal Nutrition 86, 222 228.
23. Sen, C., 1995 : Oxidants and antioxidants in exercise. Journal of Applied Physiology 79, 675 686.
24. Stowe, H. Lawler, D. Kealy, R., 2006 : Antioxidant status of pair-fed labradors retrievers is affected by diet restriction and aging. Journal of Nutrition 136, 1844 1848.
25. 13C] leucine breath test combined with indirect calorimetry of broiler chickens fed isocaloric diets with different protein: fat ratio. Journal of Animal Physiology and Animal Nutrition 91, 347 354.
26. Trinder, P., 1969 : Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor. Annals of Clinical Biochemistry 6, 24 28.
27. Vuilleumier, J. Keck, E., 1989 : Fluorimetric assay of vitamin C in biological materials using a centrifugal analyser with fluorescence attachment. Journal of Micronutrient Analysis 5, 25 34.
28. Vuilleumier, J. Keller, E. Gysel, D. Hunziker, F., 1983 : Clinical chemical methods for routine assessment of vitamin status in human populations, Part I: the fat soluble vitamin A and E and β-carotene. International Journal for Vitamin and Nutrition Research 53, 265 272.
29. Wang, S. Berge, G. Sund, R., 2001 : Plasma ascorbic acid concentrations in healthy dogs. Research in Veterinary Science 71, 33 35.
30. Wayner, D. Burton, G. Ingold, K. Barclay, L. Locke, S., 1987 : The relative contributions of vitamin E, urate, ascorbate and proteins to the total peroxyl radical-trapping antioxidant activity of human blood plasma. Biochimica et Biophysica Acta 924, 408 419.
31. Wenk, C. Leonhardt, M. Scheeder, M., 2000 : Monogastric nutrition and potential for improving muscle quality. In : E. Decker, C. Faustman, C. Lopez-Bote (eds Antioxidant in Muscle Foods, Nutritional Strategies to Improve Quality. John Wiley and Sons Inc., NY, pp. 211.