The crystal structure of human cleavage and polyadenylation specific factor-5 reveals a dimeric Nudix protein with a conserved catalytic site

Proteins: Structure, Function and Genetics

Volumn 73, Issue 4, 2008, Pages 1047-1052

  Trésaugues, Lionel ^a   Stenmark, Pål ^a,b   Schüler, Herwig ^a   Flodin, Susanne ^a   Welin, Martin ^a   Nyman, Tomas ^a   Hammarström, Martin ^a   Moche, Martin ^a   Gräslund, Susanne ^a   Nordlund, Pär ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

3 end cleavage; Endonuclease; Hydrolase; mRNA processing; Nudix motif; Protein protein interaction; RNA binding

Indexed keywords

CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 5; NUDIX HYDROLASE; UNCLASSIFIED DRUG; INORGANIC PYROPHOSPHATASE; NUDIX HYDROLASES;

AMINO TERMINAL SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVE SITE; ENZYME STRUCTURE; HUMAN; HYDROPHOBICITY; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; MOLECULAR GENETICS; PROTEIN MOTIF; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE; SEQUENCE ALIGNMENT; SURFACE PROPERTY; X RAY CRYSTALLOGRAPHY;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CATALYTIC DOMAIN; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PYROPHOSPHATASES; SEQUENCE ALIGNMENT; SURFACE PROPERTIES;

EID: 58149311440     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22198     Document Type: Article

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