Age-related responses of the rat cerebral cortex: Influence of vitamin E and exercise on the cholinergic system

Biogerontology

Volumn 10, Issue 1, 2009, Pages 53-63

  Jolitha, A B ^a   Subramanyam, M V V ^a   Asha Devi, S ^a  

^a BANGALORE UNIVERSITY   (India)

Author keywords

Acetyl choline; Acetylcholine esterase; Cerebral cortex; Choline acetyltransferase; Cognition; Exercise; Oxidative stress; Vitamin E

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; ALPHA TOCOPHEROL; CHOLINE ACETYLTRANSFERASE;

AGE DETERMINATION; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CHOLINERGIC SYSTEM; COGNITION; CONTROLLED STUDY; ENZYME ACTIVITY; EXERCISE; FORCED SWIMMING TEST; MALE; MAZE TEST; MENTAL TASK; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SPATIAL MEMORY;

ACETYLCHOLINE; ACETYLCHOLINESTERASE; AGE FACTORS; AGING; ANIMALS; ANTIOXIDANTS; CEREBRAL CORTEX; CHOLINE O-ACETYLTRANSFERASE; CHOLINERGIC FIBERS; LEARNING; MALE; MENTAL RECALL; NOOTROPIC AGENTS; PHYSICAL EXERTION; RATS; RATS, WISTAR; SWIMMING; VITAMIN E;

EID: 58149301594     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-008-9154-6     Document Type: Article

References (34)

1. Asha DS, Kiran TR (2004) Regional responses in antioxidant system in exercise training and dietary vitamin E in aging rat brain. Neurobiol Aging 25:501-508. doi: 10.1016/S0197-4580(03)00112-X
2. Asha DS, Prathima S (2005) Synergistic effects of physical exercise and antioxidants in ageing mammalian brain. In: Thakur MK, Prasad S (eds) Molecular and cellular neurobiology. Narosa Publishing House, New Delhi, pp 123-134
3. Asha DS, Prathima S, Subramanyam MVV (2003) Dietary vitamin E and physical exercise: I. Altered endurance capacity and plasma lipid profile in ageing rats. Exp Gerontol 38:285-290. doi: 10.1016/ S0531-5565(02)00206-1
4. Asha DS, Jolitha AB, Ishii N (2006) Grape seed proanthocyanidin extract (GSPE) and antioxidant defense in the brain of adult rats. Med Sci Monit 124:BR124-BR129
5. Auld DS, Kornecook TJ, Bastianetto S, Quirion R (2002) Alzheimer's disease and the basal forebrain cholinergic system: Relations to beta-amyloid peptides, cognition, and treatment strategies. Prog Neurobiol 68:209-245. doi: 10.1016/S0301-0082(02)00079-5
6. Bartus RT (2000) On neurodegenerative diseases, models, and treatment strategies: Lessons learned and lessons forgotten a generation following the cholinergic hypothesis. Exp Neurol 163:495-529. doi: 10.1006/ exnr.2000.7397
7. Bernstein D, Olton DS, Ingram DK, Waller SB, Reynolds MA, London ED (1985) Radial maze performance in young and aged mice: Neurochemical correlates. Pharmacol Biochem Behav 22:301-307. doi: 10.1016/ 0091-3057(85)90395-8
8. Blusztajn JK, Wurtmen RJ (2000) Choline and cholinenergic neurons. Science 83:614-620
9. Bures J, Buresova O, Huston JH (1976) Techniques and basic experiments for the study of brain and behaviour. Elsevier, Amsterdam
10. Canal N, Imbimbo BP (1996) Relationship between pharmacodynamic activity and cognitive effects of eptastigmine in patients with Alzheimer's disease Eptastigmine study group. Clin Pharmacol Ther 60:218-228. doi: 10.1016/S0009-9236(96)90138-1
11. Cummings JL (2000) The role of cholinergic agents in the management of behavioural disturbances in Alzheimer's disease. Int J Neuropsychopharmacol 7:21-29. doi: 10.1017/S1461145700001917
12. Desai IJ (1984) Preparation of tissues for vitamin E analysis. Methods Enzymol 105:138-147. doi: 10.1016/S0076-6879(84)05019-9
13. Durkin TP (1994) Spatial working memory over long retention intervals: dependence on sustained cholinergic activation in the septohippocampal or nucleus basalis magnocellularis-cortical pathways? Neuroscience 62:681-693. doi: 10.1016/0306-4522(94)90469-3
14. Eidi A, Eidi M, Mahmoodi G, Oryan S (2005) Effect of vitamin E on memory retention in rats: Possible involvement of cholinergic system. Eur Neuropsychopharmacol 16:101-106. doi: 10.1016/j.euroneuro.2005.06.006
15. Giacobino E, Cuadra G (1994) Second and third generation cholinesterase inhibitors: From preclinical studies to clinical efficacy. In: Giacobini E, Becker R (eds) Alzheimer's disease: Therapeutic strategies. Birkhauser, Cambridge, pp 155-171
16. Hestrin S (1949) The reaction of acetylcholine and other carboxylic acid derivatives with hydroxylamine and its analytical applications. J Biol Chem 181:249-261
17. Jolitha AB, Subramanyam MVV, Asha DS (2006) Modification by vitamin E and exercise of oxidative stress in regions of aging rat brain: Studies on superoxide dismutase isoenzymes and protein oxidation status. Exp Gerontol 41:753-763. doi: 10.1016/j.exger.2006.04.007
18. Kan S, Asha DS, Kawashima S (1991) Effect of vitamin E on the accumulation of fluorescent material in cultured cerebral cortical cells of mice. Exp Gerontol 26:365-374. doi: 10.1016/0531-5565(91)90048-Q
19. Kar S, Issa AM, Seto D, Auld DS, Collien B, Quirion R (1998) Amyloid b-peptide inhibits high-affinity choline uptake and acetylcholine release in rat hippocampal slices. J Neurochem 70:2179-2187
20. Kasa P, Rakonczay Z, Gulya K (1997) The cholinergic system in Alzheimer's disease. Prog Neurobiol 52:511-535. doi: 10.1016/ S0301-0082(97)00028-2
21. Kayden HJ, Traber MG (1993) Absorption, lipoprotein transport and regulation of plasma concentrations of vitamin E in humans. J Lipid Res 34:343-358
22. Kiran RT, Subramanyam MVV, Asha DS (2004) Swim exercise training and adaptations in the antioxidant defense system of old rats: Relationship to swim intensity and duration. Comp Physiol Biochem (Part-B) Mol Biol 137:187-196
23. Law A, Gauthier S, Quirion R (2001) Say NO Alzheimer's disease: The putative links between nitric oxide and dementia of the Alzheimer's type. Brain Res Brain Res Rev 35:73-96. doi: 10.1016/ S0165-0173(00)00051-5
24. Lohninger S, Strasser A, Bubna-Littitz H (2001) The effect of L-carnitine on T maze learning ability in aged rats. Arch Gerontol Geriatr 32:245-253. doi: 10.1016/S0167-4943(01)00097-8
25. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-267
26. Nachmansohn D, Wilson TB (1955) Choline acetylase. In: Colowick SP, Kaplan NO (eds) Methods in enzymology, vol 104. Acad. Press, New York, pp 619-624
27. Nino-Cabrere HH, Colin-Barenque L, Avila-Costa MR, Espinosa-Villanueva J, Fortoul TI, Rivas-Arancibia S (2002) Differences between hippocampus and cerebral cortex in aged rats in an oxidative stress model. Int J Neurosci 112:373-382. doi: 10.1080/00207450290025536
28. Onodera K, Nao-Om O, Fukui K, Hayasaka T, Shinkai T, Suzuki K et al (2003) Oxidative damage of rat cerebral cortex and hippocampus, and changes in antioxidative defense systems caused by hyperoxia. Free Radic Res 37:367-372. doi: 10.1080/1071576031000090019
29. Perry EK, Lee MLW, Riuz CMM, Court JA, Wilson SG, Merit J et al (2001) Cholinergic activity in autism; abnormalities in the cerebral cortex and forebrain. Am J Physiol 158:1058-1060
30. Radak Z, Kaneko T, Tahara S, Nakamato H, Puesok J, Sasvari M et al (2001) Regular exercise improves cognitive function and decreases oxidative damage in rat brain. Neurochem Int 38:17-23. doi: 10.1016/ S0197-0186(00)00063-2
31. Sarter M, Bruno JP (1998) Age-related changes in rodent cortical acetyl choline and cognition: Main effects of age versus age as an intervening variable. Brain Res Brain Res Rev 27:143-156. doi: 10.1016/ S0165-0173(98)00003-4
32. Sherman KA, Friedman E (1990) Pre- and post-synaptic cholinergic dysfynction in aged rodent brain regions: New findings and an interpretative review. Int J Dev Neurosci 8:689-708. doi: 10.1016/ 0736-5748(90)90063-8
33. Tsakiris S, Angelogianni P, Schulpis KH, Stavridis JC (2000) Protective effect of L-phenylalanine on rat brain acetylcholine esterase inhibition induced by free radicals. Clin Biochem 33:103-106. doi: 10.1016/ S0009-9120(99)00090-9
34. Vatassery GT, Brin MF, Fahn S, Kayden HJ, Traber MG (1988) Effect of high doses of dietary vitamin E on the concentrations of vitamin E in several brain regions, plasma, liver and adipose tissue of rats. J Neurochem 51:621-623. doi: 10.1111/j.1471-4159.1988.tb01083.x