Protein separation with magnetic adsorbents in micellar aqueous two-phase systems

Separation and Purification Technology

Volumn 65, Issue 1, 2009, Pages 46-53

  Becker, J S ^a   Thomas, O R T ^b   Franzreb, M ^a  

^a KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Adsorption; Affinity partitioning; Bioseparation; Cloud point extraction; Downstream processing; Magnetic separation

Indexed keywords

ADSORPTION; ANIMAL CELL CULTURE; ENZYMES; HYDROPHILICITY; MAGNETIC FIELD EFFECTS; MAGNETIC MATERIALS; MAGNETIC SEPARATION; MAGNETISM; NONIONIC SURFACTANTS; PROTEINS; SEPARATION; SOLVENT EXTRACTION; SUPRAMOLECULAR CHEMISTRY; SURFACE ACTIVE AGENTS; TWO PHASE FLOW;

AFFINITY PARTITIONING; AQUEOUS SOLUTIONS; BIOSEPARATION; CATION EXCHANGES; DOWNSTREAM PROCESSING; EXTRACTION SYSTEMS; FRACTIONATION PROCESSES; HEN EGGS; HYDROPHILIC PROTEINS; MAGNETIC ADSORBENTS; MODEL SOLUTIONS; NEW CONCEPTS; OVALBUMIN; PHASE SELECTIVITIES; PHASE SYSTEMS; PROTEIN SEPARATIONS; TARGET PROTEINS;

PHASE SEPARATION;

EID: 58149287924     PISSN: 13835866     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.seppur.2008.05.017     Document Type: Article

References (50)

1. Albertsson P.-A. Chromatography and Partition of Cells and Cell Fragments. Nature 177 (1956) 771-774
2. In: Walter H., Brooks D.E., and Fisher D. (Eds). Partitioning in Aqueous Two-Phase Systems (1985), Academic Press, London
3. Albertsson P.-A. Partition of Cell Particles and Macromolecules. third ed. (1986), John Wiley & Sons, New York
4. Zaslavsky B.Y. Aqueous Two-phase Partitioning: Physical Chemistry and Bioanalytical Applications (1995), Marcel Dekker Inc., New York
5. Raghavarao K.S.M.S., Rastogi N.K., Gowthaman M.K., and Karanth N.G. Aqueous two-phase extraction for downstream processing of enzymes/proteins. In: Neidleman S.L., and Laskin A.I. (Eds). Advances in Applied Microbiology (1995), Academic Press, San Diego 97-171
6. Kula M.-R., and Selber K. Protein purification, aqueous liquid extraction. In: Flickinger M.C., and Drew S.W. (Eds). Encyclopedia of Bioprocess Technology-Fermentation, Biocatalysis and Bioseparation (1999), Wiley, New York 2179-2191
7. Estela da Silva M., and Teixeira Franco T. Liquid-liquid extraction of biomolecules in downstream processing. Braz. J. Chem. Eng. 17 1 (2000) 1-17
8. Galaev I.Y., and Mattiasson B. Thermoreactive water-soluble polymers, nonionic surfactants, and hydrogels as reagents in biotechnology. Enzyme Microb. Tech. 15 5 (1993) 354-366
9. Sanchez-Ferrer A., Bru R., and Garcia-Carmona F. Phase separation of biomolecules in polyoxyethylene glycol nonionic detergents. Crit. Rev. Biochem. Mol. Biol. 29 4 (1994) 275-313
10. Liu C.-L., Nikas Y.J., and Blankschtein D. Partitioning of proteins using two-phase aqueous surfactant systems. AIChE J. 41 (1995) 991
11. Tani H., Kamidate T., and Watanabe H. Aqueous micellar two-phase systems for protein separation. Anal. Sci. 14 (1998) 875-888
12. Quina F.H., and Hinze W.L. Surfactant-mediated cloud point extractions: an enviromentally benign alternative separation approach. Ind. Eng. Chem. Res. 38 (1999) 4150-4168
13. Rangel-Yagui C.O., Pessoa Jr. A., and Blankschtein D. Two-phase aqueous micellar systems-an alternative method for protein purification. Braz. J. Chem. Eng. 21 4 (2004) 531-544
14. Flanagan S.D., and Barondes S.H. Affinity partitioning: a method for purification of proteins using polymer-ligands in aqueous polymer two-phase systems. J. Biol. Chem. 250 4 (1975) 1484-1489
15. Kopperschläger G., and Birkenmeier G. Affinity partitioning and extraction of proteins. Bioseparation 1 (1990) 235-254
16. Johansson G. Affinity separation|affinity partitioning in aqueous two-phase systems. In: Wilson I.D. (Ed). Encyclopedia of Separation Science (2000), Elsevier Science Ltd., Oxford 235-246
17. Xu Y., Souza M., Pontes M., Vitolo M., and Pessoa Jr. A. Liquid-Liquid extraction of enzymes by affinity aqueous two-phase systems. Braz. Arch. Biol. Techn. 46 4 (2003) 741-750
18. Xu Y., Vitolo M., Northfleet Albuquerque C., and Pessoa Jr. A. Affinity partitioning of glucose-6-phosphate dehydrogenase and hexokinase in aqueous two-phase systems with free triazine dye ligands. J. Chromatogr. B 780 1 (2002) 53-60
19. Teotia S., and Gupta M.N. Reversibly soluble macroaffinity ligand in aqueous two-phase separation of enzymes. J. Chromatogr. A 923 1-2 (2001) 275-280
20. Bordier C. Phase separation of integral membrane proteins in Triton X-114 solution. J. Biol. Chem. 256 (1981) 1604-1607
21. Saitoh T., and Hinze W.L. Use of surfactant-mediated phase separation (cloud point extraction) with affinity ligands for the extraction of hydrophilic proteins. Talanta 42 1 (1995) 119-127
22. Lee C.-K., and Su W.-D. Nonionic surfactant-mediated affinity cloud-point extraction of vancomycin. Sep. Sci. Technol. 34 16 (1999) 3267-3277
23. Lam H., Kavoosi M., Haynes C.A., Wang D.I.C., and Blankschtein D. Affinity-enhanced protein partitioning in decyl β-d-glucopyranoside two-phase micellar systems. Biotechnol. Bioeng. 89 4 (2005) 381-392
24. Lu J., Lin D.-Q., and Yao S.-J. Preparation and application of novel EOPO-IDA-metal polymer as recyclable metal affinity ligand in aqueous two-phase systems. Ind. Eng. Chem. Res. 45 5 (2006) 1774-1779
25. Hedman P.O., and Gustafsson J.-G. Protein adsorbents intended for use in aqueous two-phase systems. Anal. Biochem. 138 2 (1984) 411-415
26. Mattiasson B., and Ling T.G.I. Efforts to integrate affinity interactions with conventional separation technologies-affinity partition using biospecific chromatographic particles in aqueous two-phase systems. J. Chromatogr. B 376 (1986) 221-233
27. Ku C.-A., Henry Jr. J.D., and Blair J.B. Affinity-specific protein separations using ligand-coupled particles in aqueous two-phase systems: I. Process concept and enzyme binding studies for pyruvate kinase and alcohol dehydrogenase from Saccharomyces cerevisiae. Biotechnol. Bioeng. 33 9 (1989) 1081-1088
28. Ku C.-A., Henry Jr. J.D., and Blair J.B. Affinity-specific protein separations using ligand-coupled particles in aqueous two-phase systems: II. Recovery and purification of pyruvate kinase and alcohol dehydrogenase from Saccharomyces cerevisiae. Biotechnol. Bioeng. 33 9 (1989) 1089-1097
29. Kwon J.Y., and Hatti-Kaul R. Protein separation using metal ion-bound particles in aqueous two-phase system. Biotechnol. Tech. 13 2 (1999) 145-148
30. Kondo A., Kaneko T., and Higashitani K. Purification of fusion proteins using affinity microspheres in aqueous two-phase systems. Appl. Microbiol. Biot. 40 2-3 (1993) 365-369
31. Roobol-Boza M., Dolby V., Doverskog M., Barrefelt A., Lindqvist F., Oppermann U.C., Köhler Van Alstine K., and Tjerneld F. Membrane protein isolation by in situ solubilization, partitioning and affinity adsorption in aqueous two-phase systems. Purification pf the human type 1 11β-hydroxysteroid dehydrogenase. J. Chromatogr. A 1043 (2004) 217-223
32. Kula M.-R. Liquid-liquid extraction of biopolymers. In: Humphrey A., and Cooney C.L. (Eds). Comprehensive Biotechnology (1985), Pergamon Press, Oxford 451-471
33. Minuth T., Gieren H., Pape U., Raths H.C., Thömmes J., and Kula M.-R. Pilot scale processing of detergent-based aqueous two-phase systems. Biotechnol. Bioeng. 55 2 (1997) 339-347
34. Raghavarao K.S.M.S., Doddamane S.N., Sampangi C., and Todd P.W. Field-assisted extraction of cells, particles and macromolecules. Trends Biotechnol. 20 2 (2002) 72-78
35. Nagaraj N., Narayan A.V., Srinivas N.D., and Raghavarao K.S.M.S. Microwave-field-assisted enhanced demixing of aqueous two-phase systems. Anal. Biochem. 312 2 (2003) 134-140
36. Wikström P., Flygare S., Gröndalen A., and Larsson P.-O. Magnetic aqueous two-phase separation: a new technique to increase rate of phase-separation, using dextran-ferrofluid or larger iron oxide particles. Anal. Biochem. 167 (1987) 331-339
37. Wikström P., Flygare S., and Larsson P.-O. Magnetically enhanced aqueous two-phase separation. In: Fisher D., and Sutherland I.A. (Eds). Separations Using Aqueous Phase Systems (1989), Pienum Publishing Corporation 445-461
38. Flygare S., Wikström P., Johansson G., and Larsson P.-O. Magnetic aqueous two-phase separation in preparative applications. Enzyme Microb. Tech. 12 (1990) 95-103
39. Larsson P.-O. Magnetically enhanced phase separation. In: Walter H., and Johansson G. (Eds). Methods in Enzymology (1994), Academic Press 112-117
40. Suzuki M., Kamihira M., Shiraishi T., Takeuchi H., and Kobayashi T. Affinity partitioning of protein a using a magnetic aqueous two-phase system. J. Ferment. Bioeng. 80 1 (1995) 78-84
41. Franzreb M., Ebner N., Siemann-Herzberg M., Hobley T.J., and Thomas O.R.T. Product recovery by high-gradient magnetic fishing (HGMF). In: Etzel M., Shukla A., and Gadam S. (Eds). Process Scale Bioseparations for the Biopharmaceutical Industry (2006), CRC Press LLC
42. Franzreb M., Siemann-Herzberg M., Hobley T.J., and Thomas O.R.T. Protein purification using magnetic adsorbent particles. Appl. Microbiol. Biot. 70 5 (2006) 505-516
43. Heeboll-Nielsen A., Justesen S.F.L., Hobley T.J., and Thomas O.R.T. Superparamagnetic cation-exchange adsorbents for bioproduct recovery from crude process liquors by high-gradient magnetic fishing. Sep. Sci. Technol. 39 12 (2004) 2891-2914
44. Meyer A., Berensmeier S., and Franzreb M. Direct capture of lactoferrin from whey using magnetic micro-ion exchangers in combination with high-gradient magnetic separation. React. Funct. Polym. 67 (2007) 1577-1588
45. Brown G., Patel C., and Thomas O.R.T. Fimbriated magnetic cation exchangers for protein recovery by high-gradient magnetic fishing. Contribution to the 6th International Conference on the Scientific and Clinical Applications of Magnetic Carriers. Krems, Austria, May 17th-20th (2006)
46. Blankschtein D., Thurston G.M., and Benedek G.B. Phenomenological theory of equilibrium thermodynamic properties and phase separation of micellar solutions. J. Chem. Phys. 85 12 (1986) 7268-7288
47. Terstappen G.C., and Kula M.-R. Selective extraction quantitation of polyoxyethylene detergents and its application in protein determination. Anal. Lett. 23 12 (1990) 2175-2193
48. Terstappen G.C., Ramelmeier R.A., and Kula M.-R. Protein partitioning in detergent-based aqueous two-phase systems. J. Biotechnol. 28 2-3 (1993) 263-275
49. Desert C., Guerin-Dubiard C., Nau F., Jan G., Val F., and Mallard J. Comparison of different electrophoretic separations of hen egg white proteins. J. Agric. Food Chem. 49 10 (2001) 4553-4561
50. Nikas Y.J., Liu C.-L., Srivastava T., Abbott N.L., and Blankschtein D. Protein partitioning in two-phase aqueous nonionic micellar solutions. Macromolecules 25 (1992) 4797-4806