A dihydropyridine receptor α1s loop region critical for skeletal muscle contraction is intrinsically unstructured and binds to a SPRY domain of the type 1 ryanodine receptor

International Journal of Biochemistry and Cell Biology

Volumn 41, Issue 3, 2009, Pages 677-686

  Cui, Yanfang ^a   Tae, Han Shen ^a   Norris, Nicole C ^a   Karunasekara, Yamuna ^a   Pouliquin, Pierre ^a   Board, Philip G ^a   Dulhunty, Angela F ^a   Casarotto, Marco G ^a  

^a Biology and Environment   (Australia)

Author keywords

DHPR; Intrinsically unstructured protein; NMR; Protein protein interaction; RyR

Indexed keywords

1,4 DIHYDROPYRIDINE RECEPTOR; 1,4 DIHYDROPYRIDINE RECEPTOR ALPHA 1S; CALCIUM ION; RYANODINE RECEPTOR 1; SPROUTY PROTEIN; UNCLASSIFIED DRUG; CALCIUM CHANNEL L TYPE; CHIMERIC PROTEIN; MEMBRANE PROTEIN; PHOSPHOPROTEIN; RYANODINE RECEPTOR; SPRY1 PROTEIN, HUMAN;

ACTION POTENTIAL; ALPHA HELIX; ARTICLE; BINDING SITE; CALCIUM TRANSPORT; IN VITRO STUDY; MUSCLE CONTRACTION; NITROGEN NUCLEAR MAGNETIC RESONANCE; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; WILD TYPE; ANIMAL; CHEMISTRY; CRYSTALLIZATION; GENETICS; HUMAN; METABOLISM; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSIOLOGY; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE; SITE DIRECTED MUTAGENESIS; SKELETAL MUSCLE;

ANIMALS; BINDING SITES; CALCIUM CHANNELS, L-TYPE; CRYSTALLIZATION; HUMANS; MAGNETIC RESONANCE IMAGING; MEMBRANE PROTEINS; MUSCLE CONTRACTION; MUSCLE, SKELETAL; MUTAGENESIS, SITE-DIRECTED; MUTANT CHIMERIC PROTEINS; PHOSPHOPROTEINS; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, SECONDARY; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL;

EID: 58149284005     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2008.08.004     Document Type: Article

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