Three-dimensional location of the imperatoxin A binding site on the ryanodine receptor

Journal of Cell Biology

Volumn 146, Issue 2, 1999, Pages 493-499

  Samsó, Montserrat ^a   Trujillo, Ramon ^a   Gurrola, Georgina B ^b   Valdivia, Hector H ^b   Wagenknecht, Terence ^a,c  

^a WADSWORTH CENTER   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

^c STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Cryo electron microscopy; Excitation contraction coupling; Imperatoxin A; Ryanodine receptor; Three dimensional reconstruction

Indexed keywords

BIOTIN; DIHYDROPYRIDINE; IMPERATOXIN A; MEMBRANE PROTEIN; RYANODINE RECEPTOR; SCORPION VENOM; STREPTAVIDIN; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; EXCITATION CONTRACTION COUPLING; IMAGE ANALYSIS; MOLECULAR MIMICRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; RABBIT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; THREE DIMENSIONAL IMAGING;

ALLOSTERIC REGULATION; ANIMALS; BINDING SITES; BIOTIN; CALCIUM CHANNELS; CALCIUM CHANNELS, L-TYPE; CRYOELECTRON MICROSCOPY; CYTOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; ION CHANNEL GATING; MODELS, MOLECULAR; MOLECULAR MIMICRY; MUSCLE CONTRACTION; RABBITS; RYANODINE; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; SCORPION VENOMS; STREPTAVIDIN;

ANIMALIA; ORYCTOLAGUS CUNICULUS; SCORPIONES;

EID: 0033606795     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.146.2.493     Document Type: Article

References (29)

1. Block, B.A., T. Imagawa, K.P. Campbell, and C. Franzini-Armstrong. 1988. Structural evidence for direct interaction between the molecular components of the transverse tubule/sarcoplasmic reticulum junction in skeletal muscle. J. Cell Biol. 107:2587-2600.
2. Boisset, N., P.A. Penczek, J.C. Taveau, V. You, F. Dehaas, and J. Lamy. 1998. Overabundant single-particle electron microscope views induce a three-dimensional reconstruction artifact. Ultramicroscopy. 74:201-207.
3. Catterall, W.A. 1991. Functional subunit structure of voltage-gated calcium channels. Science. 253:1499-1500.
4. 1 subunit required for activation of skeletal muscle-type excitation-contraction coupling. Biochemistry. 37:7015-7020.
5. El-Hayek, R., B. Antoniu, J. Wang, S.L. Hamilton, and N. Ikemoto. 1995a. Identification of calcium release-triggering and blocking regions of the II-III loop of the skeletal muscle dihydropyridine receptor. J. Biol. Chem. 270: 22116-22118.
6. El-Hayek, R., A.J. Lokuta, C. Arevalo, and H.H. Valdivia. 1995b. Peptide probe of ryanodine receptor function. Imperatoxin A, a peptide from the venom of the scorpion Pandinus imperator, selectively activates skeletal-type ryanodine receptor isoforms. J. Biol. Chem. 270:28696-28704.
7. Frank, J. 1996. Three-Dimensional Electron Microscopy of Macromolecular Assemblies. Academic Press, New York.
8. Frank, J., M. Radermacher, P. Penczek, J. Zhu, Y. Li, M. Ladjadj, and A. Leith. 1996. SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields. J. Struct. Biol. 116:190-199.
9. Franzini-Armstrong, C., and F. Protasi. 1997. Ryanodine receptors of striated muscles: a complex channel capable of multiple interactions. Physiol. Rev. 77:699-729.
10. Gurrola, G.B., C. Arevalo, R. Sreekumar, A.J. Lokuta, J.W. Walker, and H.H. Valdivia. 1999. Activation of ryanodine receptors by imperatoxin A and a peptide segment of the II-III loop of the dihydropyridine receptor. J. Biol. Chem. 274:7879-7886.
11. Leong, P., and D.H. MacLennan. 1998a. A 37-amino acid sequence in the skeletal muscle ryanodine receptor interacts with the cytoplasmic loop between domains II and III in the skeletal muscle dihydropyridine receptor. J. Biol. Chem. 273:7791-7794.
12. Leong, P., and D.H. MacLennan. 1998b. The cytoplasmic loops between domains II and III and domains III and IV in the skeletal muscle dihydropyridine receptor bind to a contiguous site in the skeletal muscle ryanodine receptor. J. Biol. Chem. 273:29958-29964.
13. Lu, X., L. Xu, and G. Meissner. 1994. Activation of the skeletal muscle calcium release channel by a cytoplasmic loop of the dihydropyridine receptor. J. Biol. Chem. 269:6511-6516.
14. 687. J. Biol. Chem. 270:18459-18464.
15. f and fitting of L1 protein. J. Mol. Biol. 280:103-116.
16. Nakai, J., T. Tanabe, T. Konno, B. Adams, and K.G. Beam. 1998. Localization in the II-III loop of the dihydropyridine receptor of a sequence critical for excitation-contraction coupling. J. Biol. Chem. 273:24983-24986.
17. Orlova, E.V., I.I. Serysheva, M van Heel, S.L. Hamilton, and W. Chiu. 1996. Two structural configurations of the skeletal muscle calcium release channel. Nature Struct. Biol. 3:547-552.
18. Penczek, P.A., R.A. Grassucci, and J. Frank. 1994. The ribosome at improved resolution: new techniques for merging and orientation refinement in 3D cryo-electron microscopy of biological particles. Ultramicroscopy. 53:251-270.
19. Radermacher, M., V. Rao, R. Grassucci, J. Frank, A.P. Timerman, S. Fleischer, and T. Wagenknecht. 1994. Cryo-electron microscopy and three-dimensional reconstruction of the calcium release channel ryanodine receptor from skeletal muscle. J. Cell Biol. 127:411-423.
20. Rios, E., and G. Pizarro. 1991. Voltage sensor of excitation-contraction coupling in skeletal muscle. Physiol. Rev. 71:849-908.
21. Samsó, M., and T. Wagenknecht. 1998. Contributions of electron microscopy and single-particle techniques to the determination of the ryanodine receptor three-dimensional structure. J. Struct. Biol. 121:172-180.
22. Schneider, M.F., and W.K. Chandler. 1973. Voltage dependent charge movement of skeletal muscle: a possible step in excitation-contraction coupling. Nature. 242:244-246.
23. Serysheva, I.I., E.V. Orlova, W. Chiu, M.B. Sherman, S.L. Hamilton, and M. van Heel. 1995. Electron cryomicroscopy and angular reconstitution used to visualize the skeletal muscle calcium release channel. Nature Struct. Biol. 2:18-24.
24. 2+ release events by imperatoxin A in frog skeletal muscle. Biophys. J. 76:A465.
25. Tanabe, T., K.G. Beam, B.A. Adams, T. Nicodome, and S. Numa. 1990. Regions of the skeletal muscle dihydropyridine receptor critical for excitation-contraction coupling. Nature. 346:567-569.
26. 2+ release channels (ryanodine receptors) of cardiac and skeletal muscle. J. Gen. Physiol. 111:679-690.
27. Wagenknecht, T., M. Radermacher, R. Grassucci, J. Berkowitz, H.-B. Xin, and S. Fleischer. 1997. Locations of calmodulin and FK506-binding protein on the three-dimensional architecture of the skeletal muscle ryanodine receptor. J. Biol. Chem. 272:32463-32471.
28. Yu, X., T. Shibata, and E.H. Egelman. 1998. Identification of a defined epitope on the surface of the active recA-DNA filament using a monoclonal antibody and three-dimensional reconstruction. J. Mol. Biol. 283:985-992.
29. 2+ release channels ryanodine receptors. FEBS (Fed. Eur. Biochem. Soc.) Lett. 405:385-389.