Erythropoietin attenuates ischemia-reperfusion induced lung injury by inhibiting tumor necrosis factor-α and matrix metalloproteinase-9 expression

European Journal of Pharmacology

Volumn 602, Issue 2-3, 2009, Pages 406-412

  Wu, Haiwei ^a   Dong, Guohua ^a   Liu, Hao ^a   Xu, Biao ^a   Li, Demin ^a   Jing, Hua ^a  

^a JINLING HOSPITAL   (China)

Author keywords

Erythropoietin; Ischemia reperfusion; Lung injury; Matrix metalloproteinase 9; Tumor necrosis factor

Indexed keywords

GELATINASE B; MALONALDEHYDE; MYELOPEROXIDASE; RECOMBINANT ERYTHROPOIETIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS CELL; LUNG INJURY; MALE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY;

ANIMALS; APOPTOSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROPOIETIN; GENE EXPRESSION REGULATION; LUNG INJURY; MALE; MALONDIALDEHYDE; MATRIX METALLOPROTEINASE 9; PEROXIDASE; PULMONARY ALVEOLI; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 58149279262     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.11.037     Document Type: Article

References (31)

1. Buemi M., Cavallaro E., Floccari F., Sturiale A., Aloisi C., Trimarchi M., Corica F., and Frisina N. The pleiotropic effects of erythropoietin in the central nervous system. J. Neuropathol. Exp. Neurol. 62 (2003) 228-236
2. Cuzzocrea S., Mazzon E., Di Paola R., Patel N.S., Genovese T., Muia C., De Sarro A., and Thiemermann C. Erythropoietin reduces the development of experimental inflammatory bowel disease. J. Pharmacol. Exp. Ther. 311 (2004) 1272-1280
3. de Perrot M., Liu M., Waddell T.K., and Keshavjee S. Ischemia-reperfusion-induced lung injury. Am. J. Respir. Crit. Care Med. 167 (2003) 490-511
4. Di Santo E., Adami M., Bertorelli R., and Ghezzi P. Systemic interleukin 10 administration inhibits brain tumor necrosis factor production in mice. Eur. J. Pharmacol. 336 (1997) 197-202
5. Eid T., and Brines M. Recombinant human erythropoietin for neuroprotection: what is the evidence?. Clin. Breast Cancer 3 Suppl 3 (2002) S109-S115
6. Fandrey J., and Jelkmann W.E. Interleukin-1 and tumor necrosis factor-alpha inhibit erythropoietin production in vitro. Ann. N.Y. Acad. Sci. 628 (1991) 250-255
7. Grimm C., Wenzel A., Groszer M., Mayser H., Seeliger M., Samardzija M., Bauer C., Gassmann M., and Reme C.E. HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration. Nat. Med. 8 (2002) 718-724
8. Imamura R., Isaka Y., Ichimaru N., Takahara S., and Okuyama A. Carbamylated erythropoietin protects the kidneys from ischemia-reperfusion injury without stimulating erythropoiesis. Biochem. Biophys. Res. Commun. 353 (2007) 786-792
9. Jelkmann W., Wolff M., and Fandrey J. Modulation of the production of erythropoietin by cytokines: in vitro studies and their clinical implications. Contrib. Nephrol. 87 (1990) 68-77
10. Kadri Z., Petitfrere E., Boudot C., Freyssinier J.M., Fichelson S., Mayeux P., Emonard H., Hornebeck W., Haye B., and Billat C. Erythropoietin induction of tissue inhibitors of metalloproteinase-1 expression and secretion is mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways. Cell Growth Differ. 11 (2000) 573-580
11. Kamoshita N., Takeyoshi I., Ohwada S., Iino Y., and Morishita Y. The effects of FR167653 on pulmonary ischemia-reperfusion injury in dogs. J. Heart Lung Transplant. 16 (1997) 1062-1072
12. Lipsic E., Schoemaker R.G., van der Meer P., Voors A.A., van Veldhuisen D.J., and van Gilst W.H. Protective effects of erythropoietin in cardiac ischemia: from bench to bedside. J. Am. Coll. Cardiol. 48 (2006) 2161-2167
13. Leist M., P.G., Grasso G., Bianchi R., Villa P., Fratelli M., Savino C., Bianchi M., Nielsen J., Gerwien J., Kallunki P., Larsen A.K., Helboe L., Christensen S., Pedersen L.O., Nielsen M., Torup L., Sager T., Sfacteria A., Erbayraktar S., Erbayraktar Z., Gokmen N., Yilmaz O., Cerami-Hand C., Xie Q.W., Coleman T., and A. Derivatives of erythropoietin that are tissue protective but not erythropoietic. Science 305 (2004) 239-242
14. Maiese K., Li F., and Chong Z.Z. New avenues of exploration for erythropoietin. Jama 293 (2005) 90-95
15. Maxey T.S., Enelow R.I., Gaston B., Kron I.L., Laubach V.E., and Doctor A. Tumor necrosis factor-alpha from resident lung cells is a key initiating factor in pulmonary ischemia-reperfusion injury. J. Thorac. Cardiovasc. Surg. 127 (2004) 541-547
16. Menger M.D., and Vollmar B. Pathomechanisms of ischemia-reperfusion injury as the basis for novel preventive strategies: is it time for the introduction of pleiotropic compounds?. Transplant. Proc. 39 (2007) 485-488
17. Ng C.S., Wan S., Arifi A.A., and Yim A.P. Inflammatory response to pulmonary ischemia-reperfusion injury. Surg. Today 36 (2006) 205-214
18. Ozer E.A., Kumral A., Ozer E., Yilmaz O., Duman N., Ozkal S., Koroglu T., and Ozkan H. Effects of erythropoietin on hyperoxic lung injury in neonatal rats. Pediatr. Res. 58 (2005) 38-41
19. Quadri S.M., Segall L., de Perrot M., Han B., Edwards V., Jones N., Waddell T.K., Liu M., and Keshavjee S. Caspase inhibition improves ischemia-reperfusion injury after lung transplantation. Am. J. Transplant. 5 (2005) 292-299
20. Sakanaka M., Wen T.C., Matsuda S., Masuda S., Morishita E., Nagao M., and Sasaki R. In vivo evidence that erythropoietin protects neurons from ischemic damage. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 4635-4640
21. Sepodes B., Maio R., Pinto R., Sharples E., Oliveira P., McDonald M., Yaqoob M., Thiemermann C., and Mota-Filipe H. Recombinant human erythropoietin protects the liver from hepatic ischemia-reperfusion injury in the rat. Transpl. Int. 19 (2006) 919-926
22. Solaroglu A., Dede F.S., Okutan E., Bayrak A., Haberal A., and Kilinc K. A single dose of erythropoietin attenuates lipid peroxidation in experimental liver ischemia-reperfusion injury in the rat fetus. J. Matern. Fetal Neonatal Med. 16 (2004) 231-234
23. Squadrito F., Altavilla D., Squadrito G., Campo G.M., Arlotta M., Quartarone C., Saitta A., and Caputi A.P. Recombinant human erythropoietin inhibits iNOS activity and reverts vascular dysfunction in splanchnic artery occlusion shock. Br. J. Pharmacol. 127 (1999) 482-488
24. Tascilar O., Cakmak G.K., Tekin I.O., Emre A.U., Ucan B.H., Bahadir B., Acikgoz S., Irkorucu O., Karakaya K., Balbaloglu H., Kertis G., Ankarali H., and Comert M. Protective effects of erythropoietin against acute lung injury in a rat model of acute necrotizing pancreatitis. World J. Gastroenterol. 13 (2007) 6172-6182
25. Vairano M., Dello Russo C., Pozzoli G., Battaglia A., Scambia G., Tringali G., Aloe-Spiriti M.A., Preziosi P., and Navarra P. Erythropoietin exerts anti-apoptotic effects on rat microglial cells in vitro. Eur. J. Neurosci. 16 (2002) 584-592
26. Villa P., Bigini P., Mennini T., Agnello D., Laragione T., Cagnotto A., Viviani B., Marinovich M., Cerami A., Coleman T.R., Brines M., and Ghezzi P. Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis. J. Exp. Med. 198 (2003) 971-975
27. Viviani B., Corsini E., Galli C.L., Padovani A., Ciusani E., and Marinovich M. Dying neural cells activate glia through the release of a protease product. Glia 32 (2000) 84-90
28. Wu H., Ren B., Zhu J., Dong G., Xu B., Wang C., Zheng X., and Jing H. Pretreatment with recombined human erythropoietin attenuates ischemia-reperfusion-induced lung injury in rats. Eur. J. Cardio-Thorac. Surg. 29 (2006) 902-907
29. Yano M., Omoto Y., Yamakawa Y., Nakashima Y., Kiriyama M., Saito Y., and Fujii Y. Increased matrix metalloproteinase 9 activity and mRNA expression in lung ischemia-reperfusion injury. J. Heart Lung Transplant. 20 (2001) 679-686
30. Yildirim E., Solaroglu I., Okutan O., Ozisik K., Kaptanoglu E., Sargon M.F., and Sakinci U. Ultrastructural changes in tracheobronchial epithelia following experimental traumatic brain injury in rats: protective effect of erythropoietin. J. Heart Lung Transplant. 23 (2004) 1423-1429
31. Yildirim E., Ozisik K., Solaroglu I., Kaptanoglu E., Beskonakli E., Sargon M.F., Kilinc K., and Sakinci U. Protective effect of erythropoietin on type II pneumocyte cells after traumatic brain injury in rats. J. Trauma 58 (2005) 1252-1258